menulis systimatic review -...
TRANSCRIPT
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Menulis Systematic
reviewPUDJI LESTARI
DEPARTEMEN IKM-KP FAKULTAS KEDOKTERAN UNAIR
EMAIL: [email protected] HP 0818371734
mailto:[email protected]
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What is a systematic review?
SYSTEMATIC: Done or acting according to a fixed plan or system: methodical
REVIEW: A critical appraisal of a book, play or other work
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What is a systematic review?
“A systematic review is a review in which there is a comprehensive search for relevant studies on a specific topic, and those identified are then appraised and synthesized according to a predetermined and explicit method.”
(Klassen et al. Guides for reading and interpreting systematic reviews.
Arch Pediatr Adolesc Med 1998;152:700-704.)
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Literature review
Membahas satu
aspek/bagian bidang
ilmu, tanpa
pertanyaan.
Co : Penggunaan
methadone
replacement untuk
adiksi heroin pada
remaja
Systematic review
Berusaha menjawab
pertanyaan spesifik dalam satu
bidang ilmu
Co : Apakah methadone
replacement lebih efektif
dalam penanganan adiksi
heroin pada remaja
dibandingkan dengan tanpa
replacement ?
https://www.cochrane.org/CD
002209/ADDICTN_methadone-
maintenance-therapy-versus-
no-opioid-replacement-
therapy
https://www.cochrane.org/CD002209/ADDICTN_methadone-maintenance-therapy-versus-no-opioid-replacement-therapy
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Cara mencari jurnal
Jurnal /artikel dicari
dalam data based
tanpa metode
tertentu, yang penting
relevan dengan topic
yang sedang ditulis.
Mencari artikel dalam
data based secara
systematic dengan
metode tertentu sesuai
tujuan pertanyaan
Contoh: menggunakan
MeSH term yang sesuai,
hanya memasukkan RCT,
dalam lima tahun
terakhir.
Literature review Systematic review
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Cara menilai/meresume jurnal
Tidak spesifik, Dibaca
dan diresume sesuai
alur dan sudut
pandang penulis ,
Menggunakan tool tertentu dandikerjakan secarasubyektif (biasanyalebih dari satupeneliti).
Contoh Tool : MMAT2018;NOSGEN
Prisma; Cochran (membership)
Literature review Systematic review
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Jumlah jurnal (for decent one)
lebih dari 100 jurnal,
lebih banyak lebih
bagus
Biasanya kurang dari 30,
sering kali kurang dari
10 karena harus
memenuhi kriteria inklusi
Systematic reviewLiterature review
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Beda dengan Meta analisis
Bila analisis heterogenitas jurnal
dan resume jurnal menggunakan
statistik maka systematic review
disebut meta analisis.
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Lima langkah menulis Systematic
review
1. Menemukan pertanyaan
2. Menetapkan protocol pencarian jurnal yang
sesuai
3. Melakukan penilaian jurnal
4. Meresume Jurnal
5. Menarik kesimpulan
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Step 1 . Menemukan Pertanyaan
Yang biasanya merupakan kontroversi (dalam
pengobatan)
Contoh :
length of maintenance antipsychotic treatment in
schizophrenia;
The use of antidepressants in minor depression;
Hallucinogen psilocybin in magic mushroom
for depression, anxiety and addiction ;
Electroconvulsive therapy (ECT) for schizophrenia ;
Deep brain stimulation for OCD
https://www.livescience.com/19154-shock-therapy-depression-treatment.html
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The PICO’s
Source :
https://libguides.ul.ie/c.php?g=328865&p=2208907
https://libguides.ul.ie/c.php?g=328865&p=2208907
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Length of maintenance
antipsychotic treatment in
schizophrenia
P : schizophrenia patients (age ?/sex?)
I : anti psychotic treatment for how long ?
(10 year ? 15 year?)
C : compare to how long (1 year / 5
year?)
O: Quality of life ?, frekuensi gaduh
gelisah?, Koherensi ? Insight?
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the use of Corticosteroid on DHF
P :penderita DHF dewasa muda di
Surabaya
I : corticosteroid dosis tinggi
C : tanpa corticosteroid
O : kadar trombosit/ tensi/nadi
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Step 2 : Set up protocol for
searching the journal
Tetapkan kata kunci
Tetapkan rentang waktu
Tetapkan data base
Tetapkan bahasa
Gunakan MeSH term
Gunakan Boolean logic
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Boolean Logic: AND
this is AND zone, covering common area
between two ellipses
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Boolean Logic OR
this is boolean OR, covering the two
ellipses
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Contoh :
Electronic searches were performed using the PubMed (1 January
1990–1 July 2015), LILACS (1 January 1990–1 July 2015) and SciELO (1 January 1990–1 July 2015) databases.
The following key words were used: ayahuasca OR psilocybin OR
lysergic acid diethylamide AND anxiety OR depression OR
dependence. References were retrieved through searching
electronic databases and manual searches through reference lists
of identified literature. All studies published in English, Spanish, and
Portuguese up to 1 July 2015 were included.
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Set up protocol for searching the
journal
Contoh :
https://www.cochranelibrary.com/cdsr/doi/10.1002/1465
1858.CD002209.pub2/full
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910400
/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241490
/
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD002209.pub2/fullhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910400/https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241490/
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Trick : How to use the MeSH term
https://www.youtube.com/watch?v=0GGhgbwU9Cs
https://www.youtube.com/watch?v=0GGhgbwU9Cs
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Step 2. Mengidentifikasi Jurnal2
yang relevan
RCT’s
Perlakuan yang spesifik
Symptom yang diinginkan
Alat ukur yang diinginkan
Ketersediaan
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Contoh :
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Step 3. Menilai kualitas Jurnal
http://mixedmethodsappraisaltoolpublic.pbworks.com/w/file/fetch/
127916259/MMAT_2018_criteria-manual_2018-08-01_ENG.pdf
https://guides.mclibrary.duke.edu/c.php?g=158178&p=1035917
http://www.ohri.ca/programs/clinical_epidemiology/nosgen.pdf
CONSORT (keseluruhan Jurnal)
http://www.consort-statement.org/checklists/view/32--consort-
2010/66-title
http://mixedmethodsappraisaltoolpublic.pbworks.com/w/file/fetch/127916259/MMAT_2018_criteria-manual_2018-08-01_ENG.pdfhttps://guides.mclibrary.duke.edu/c.php?g=158178&p=1035917http://www.ohri.ca/programs/clinical_epidemiology/nosgen.pdfhttp://www.consort-statement.org/checklists/view/32--consort-2010/66-title
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Step 4. Meresume
Tanpa statistic : systematic review
Dengan statistic : Forest plot, Funnel plot
(meta analisis )
Author/studi n (jumlah sample) Intervensi Comparasi Outcome
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Diskusi
https://www.researchgate.net/figure/Narrative-synthesis-framework-Modifi-ed-from-14-41_fig2_232612227
https://www.researchgate.net/figure/Narrative-synthesis-framework-Modifi-ed-from-14-41_fig2_232612227
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Step 5 Menarik kesimpulan
Menjawab PICO, dengan spectrum dan konteks
Methadone is an effective maintenance therapy
intervention for the treatment of heroin dependence as
it retains patients in treatment and decreases heroin use
better than treatments that do not utilize opioid
replacement therapy. It does not show a statistically
significant superior effect on criminal activity or mortality.
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Futher reading
http://dal.ca.libguides.com/systematicreviews/appraisal
https://www.ccace.ed.ac.uk/research/software-
resources/systematic-reviews-and-meta-analyses
https://lib.guides.umd.edu/SR/steps
http://dal.ca.libguides.com/systematicreviews/appraisalhttps://www.ccace.ed.ac.uk/research/software-resources/systematic-reviews-and-meta-analyseshttps://lib.guides.umd.edu/SR/steps