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Mechanical Engineering Dr. Neal Murphy 12 th November 2013

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Page 1: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mechanical Engineering

Dr. Neal Murphy

12th November 2013

Page 2: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Power generation

What do mechanical engineers do...?

Page 3: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Transport

What do mechanical engineers do...?

Page 4: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Biomedical

What do mechanical engineers do...?

Page 5: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Manufacturing

What do mechanical engineers do...?

Page 6: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

What do mechanical engineers do...?

Management

Page 7: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

What will you study..? Thermodynamics

Page 8: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

What will you study..? Dynamics

Page 9: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

What will you study..? Control

Page 10: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

What will you study..? Electrical and electronic engineering

Page 11: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

What will you study..? Materials

Page 12: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

What will you study..? Mechanics of Materials

Page 13: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

What will you study..? Fluid Mechanics and Heat Transfer

Page 14: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

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Stage 1 (60 Credit)

Stage 2 (60 Credit)

Stage 3 (60 Credit)

Single-Stage ME (2-years, 120 Credit) !+,&*#-!'.!/(0%(##-%(0!1+/89!&I#$%,4%&%(0!%(NNN!!

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Stage 4 BE (60 Credit)

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Stage 1 (60 Credit)

Engineering and Architecture Programme Office/Dr David Timoney, October 2011

Page 15: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical
Page 16: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

School of Mechanical and Materials Engineering College of Engineering and Architecture University College Dublin

Mechanical Engineering

John Adams BE, PhD

Page 17: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Introduction

•  Why am I here speaking to you? –  First hand experience –  Example of typical career path

•  Plan for today’s presentation –  Example careers from my classmates –  My own research –  My time in industry –  Overview of the possible options with a Mechanical Eng. Degree

Page 18: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

My Class •  Graduated 2005

Page 19: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

My Education and Work to Date!!

•  BE Mechanical Engineering from

•  PhD from

•  Research and Development Engineer in

•  Product Development Engineer in

Page 20: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

My Education and Work to Date!!

•  BE Mechanical Engineering from

•  PhD from

•  Research and Development Engineer in

•  Product Development Engineer in

Page 21: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Research: Mitral Heart Valve

Page 22: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Ischaemic Mitral Regurgitation

•  Retrograde flow of blood through MV

•  IMR arises as a consequence of reduced blood flow to myocardium

•  7.9 Million Americans suffer Myocardial Infarction

•  19% of these suffer IMR

Page 23: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Treatment Strategies

•  A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical trials

•  Retrospective studies have shown valve repair to be optimal treatment with lower perioperative mortality and long-term morbidity, increased survival and preservation of LV function

•  Novel Treatment Strategies – Percutaneous delivery of repair element

Page 24: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

To Pump

Compliance and resistance

Aortic Head Tank

Left Atrial Tank

Prosthetic Aortic Valve

Papillary Muscle Support

arms

Mitral annulus plate

Mitral Model – Flow Loop

Page 25: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Model - Pulse Duplicator

Page 26: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Coaptation – Dynamic

Page 27: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Force Measurement •  3 axis force sensor

•  Chordae tendinae tension sensor

•  Coaptation Probe

Page 28: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Coaptation – Static

Page 29: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Coaptation – Static

Page 30: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Model - Annulus Plate

Page 31: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Model - Annulus Plate

Page 32: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Coaptation – Dynamic

Page 33: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Coaptation Forces

Page 34: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Coaptation Forces

Page 35: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Mitral Coaptation Forces

Page 36: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

PhD Complete

Page 37: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Product Development Engineer: Nypro

•  Location: Bray

•  Work force: 320

•  Designs, Develops and Manufactures Injection Moulded Medical Devices

Page 38: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Device Development Centre

Page 39: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

•  Clean Room Facilities

•  High Volume Manufacture –  60,000,000 Devices per year

•  High Volume Assembly

Page 40: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

•  Core Business is Plastic Injection Moulding

Page 41: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

•  Specialises in Drug Delivery Devices

Page 42: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

•  DDS Group uses Predictive Mechanical Design

Page 43: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

•  DDS Group caries out design for manufacture and manages tool design

Page 44: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

•  Medical Device Packaging / Cartridges

Page 45: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

•  Operations Group control/optimise processes

Page 46: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

How has a Mechanical Engineering Degree Helped me?

•  Core Engineering Skills: Understand fundamentals

•  Problem Solving Ability

•  Flexibility to adapt to roles

•  Speed of learning

Page 47: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

My Class •  Graduated 2005

Page 48: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

My Class

•  Materials Science

•  Failure Analysis

•  Thermodynamics

•  Energy Conversion Systems

•  Fluid Dynamics

•  Control Systems

•  Electronic and Electrical

Page 49: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

My Class

•  Materials Science

•  Thermodynamics

•  Fluid Dynamics

•  Control Systems

•  Continuum Mechanics

Page 50: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

My Class

•  Process optimisation

•  Resource Management

•  Manufacturing

Page 51: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

My Class

•  Project Management

•  Accounting

•  Logical Problem Solving

•  Flexible learning

•  Operational sales

Page 52: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Do What Interests You!

•  Go for opportunities that interest you.

•  Enter competitions

•  Overseas learning

•  Scholarships

•  Research Projects

Page 53: Mechanical Engineering Dr. Neal Murphy Engineering Nov 2013.pdf · • A comprehensive evaluation of the efficacy of MV treatment has been hindered by the lack of randomized clinical

Thank you