mammary gland by : erma safitri, m.si., drh. faculty of veterinary medcine airlangga university...
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MAMMAry gland
By :Erma Safitri, M.Si., Drh.
Faculty of Veterinary MedcineAirlangga University
Surabaya
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ANATOMY OF MAMMARY GLANDModificated : Skin Gland + Nepple + Water Milk
Homologue : Sweat Gland
Based of Location :
1. Inguinale : Cow, Ewe, Goat, Buffalo, Mare
2. Pectoralis : Elephant & Primate
3. Abdominalis : Sow, Dog, Cat
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Mammary Gland : Σ, Form, Measurrement & Located : Different
Base Structure : Same
Consist of :
1. Sekretion Tissue/Parenchima: Epithel Sekretion Cell
(ALVEOLI)
2. Binding Tissue (STROMA)
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In 1 Kuartir consist of 1 Teat Sisterna & 1 Streak Canal (Teat Meatus)
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In 1 Kuartir consist 2 Teat Sisterna & 2 streak canal
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In 1 Kuartir consist of Many Teat Sisterna & Many Streak Canal
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Milk Product ↗ Average Milk Product Milk Product ↓
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With TRUNKFor suckling With Mouth
For suckling
Process PencarianPutting Susu
With Botle milk
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Adhesion of Mammary Gland by :1. Skin2. Lig. Suspensorium medialis : Yellow, Elastis
Tissue, Lamellae Formed/ Lempengan3. Lig suspensorium lateralis: Fibrous Tissue, Terminate on Tendon from os Ischium & Pubis
ALVEOLI : like Grappes FruitLike Lung TissueDiameter : 0,1 – 0,3 mmConsist : Stratum of Epitel Secretori Cell
Function : (Side of Produce/ Milk Syntesis)1.Take of Nutrient from Blood2. Change of nutrient from Blood3. Flow of Nutrient to the Lumen
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Each of Kuartir separated in :Blood Suplai , Nervous Suplai & Ligamentum (Lateralis & Medialis)
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Each of Mammary separated in :1.Suplai Darah2. Suplai Syaraf3. Aparatus Suspensorius: Lig. Susp. Lat & Med
SIRKULATION1. PUDICUM EXTERNA Artery MAMMARICA EXTERNA Artery CAPILER System in the ALVEOLUS2. VENA : Anastomose - 2 track = CAVA Vein PUDICUM EXTERNA Vein SUBCUTANEUS ABDOMINALIS Vein (Milk Vein)
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INERVATION/ STIMULATION :1. HORMONE MECHANISME2. NEURAL MECHANISME : A. AUTONOMIC : INTERNAL (Induk) B. SOMATIS : EKSTERNAL (Suckling, Habitualis)
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PROCCES OF MILK
SYNTESIS
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PROLIFERATION & FUNCTION OF MAMMARY GLAND:
1. MAMMOGENESIS Proliferation of Mammary Gland to indicated with Proliferation of Cell
2. LACTOGENESIS Sintesys to Produce/ Milk Sekretion
3. GALACTOPOIESIS Maintenance of Milk Suplai (Laktation)
4. MILK EJECTION Milk go out in large number from ALVEOLI Ejection from Mammary Gland b/ Suckling
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1. MAMMOGENESIS : Proliferation control of Mammary Gland E2 : Proliferation of Ductus system (in Every Estrous & Pregnant) P4 : Proliferation of Mammary Alveolar
HORMONE MECHANISME HIPOTALAMUS
GH PRL HIPOFISA ANTERIOR
DUCTUS OVARIUM ALVEOLI E2
P4
PLACENTA PLACENTALACTOGEN
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PLASENTAL LACTOGEN = SOMATOMAMMOTROPHINE Structure & Biology Aktivity Like GH & PRL Produced by Placenta
2. LACTOGENESIS : At GRAVID Phase: E2 + P4 ↗↗ PRL↙ Stopped At PARTUS/ OVARIECTOMY/ INVOLUTIO CL Become
MECHANISME :PARTUS P4↙↙↙ & E2↙
HIPOFISA ANTERIOR
PROLAKTIN
MILK SECRETION
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3. GALACTOPOIESIS : Hipofisa Gland : Important for Laktation maintenance PRL : shock for milk secretion
HORMONES THE ROLE OF GLAND PROLIFERATION FSH
LHLTH/ PRLACTHTSHE2P4PLASENTA LACTOGEN
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SUCKLING
IMPULS SYARAF
N. PARAVENTR. HIPOTHALAMUS
OXITOCYN
HIPOFISA POST.
BLOOD VESSEL
CONTRACTION OF MYOEPITHEL CELLS
MILK EJECTION
Trac. Hipothalamico- Hipofiseal
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LAKTASI TDD 2 FASE: SEKRESI & PELEPASAN AS
MEKANISME SEKRESI:
HIPOFISA ANTERIOR
FSH & LH
OVARIUM
PERTUMB. DUCT P4↗↗
E2↗ PERTUMB. ALVEOLI
PARTUS
E2↙, P4↙ & Suckling
H.A. LTH
INISIASI LAKTASI
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1. There isn’t Suckling2. Disturb of Milk Ejection : Worry, Afraid,
Bashful, Sad & High Emotion3. Tx/ EPINEPPRIN: Stimulate inhibiting of
nervous to Neurohypofisis so that didn’t out of oxytocin
4. Cutting of Pituitary stalk5. Demaging of Hipothalamus region
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STOPPED LAKTATION RATHER QUICKLYIf Mammary Gland full filled b/ :
there isn’t Suckling/ Disturb milk ejection
ALVEOLI produced continuesly & full filed
Raising of mammary gland tension
b/ There isn’t Suckling/ Distrubed
Tension will grow up reached Max point
MILK SEKRETION DELAYED
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1. Time must constant squezing 2. Sound of bucket3. There is a Calf
4. Washing of Mammary5. Look at food (Habitualis)6. Genital Manipulation7. Matting8. R/ Oxytocin eksogen9. Electrical Stimulate for Tractus
Supraoptico-Hipofisialis
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= Basket, Arround of AlveoliIt’s. Efector contractile tissueIt’s Cells with stuck out, branch off &
not Arranged Can Contraction with R/ : Local Oksitocyn/ Vasopresin,
Histamin, Asetilcholine & Philocarpine
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