literature of the chemical periphery i. cancer

Literature of the Chemical PeripheryI. Cancer'

By HAROLD OATFIELDDivision of Medical Sciences, NationalResearch Council, Washington, D. C.

HEMISTRY is a multifaceted science whose each face touches on a dif-ferent phase of human endeavor. From a trend which began with coining namesfor work areas called physical chemistry, and physiological chemistry (Prof.Miles Burkitt of Cambridge speaks of the recent hiving off of biochemistry as aseparate subject from its parent sciences) and hasprogressed through biophysicsto a supposed need for anomalously named periodicals such as Biochimica etBiophysica A cta, has come an era in which leading centers of learning have pro-fessors of Biophysical Chemistry, and perhaps eventually may tolerate eventitles like Paleobotanical Spectroscopy or Forensic Oncology. Hence it has be-come necessary to blaze paths (occasionally maze-like in themselves) for newworkers to find their way to the known results which they need to assimilate inorder to pursue their own research.As the frontiers of science gradually retreat before the continuous assault, a

common work area is reached. Crowther in his Thompson Memorial Lecture2in 1938 said "for further advances we must look to cooperation between biol-ogists and physicists and chemists." Of course, Dr. Crowther was speaking ofour understanding of the biological action of x-rays, but he might easily havebeen talking about any one of a dozen other such technical melanges. The inter-disciplinary study is prevalent today. As a result there is a need for the chemistto delve into much literature, to him relatively uncharted, although he con-tinues to benefit by a literature ably organized around outstanding abstractingsources in his own discipline.

Chemical Abstracts has kept in the forefront by revising its subclasses as con-ditions have warranted. Its Section 11 serves as a starting point in penetratingthe growing number of new mutual areas of interest arising from the mating ofChemistry with that polyandrous discipline called Biology. Too often, however,a chemist will stop there.

I propose here to indicate some of the basic literature sources, in addition to

1Presented before the Division of Chem. Education, 114th National Meeting A.C.S.in Portland, September 13, 1948. Part II will appear subsequently.

2Brit. J. Radiology, 11: 132, 1938.

9

HAROLD OATFIELD

Chemical Abstracts, which may aid chemists who wish to work in these intrigu-ing fields on the periphery of their fundamental science. Detailed classified listsare appended.

I. CANCER

A field attracting the efforts of many chemists today is cancer re-search. Greenstein3 has said that "cancer research or oncology is not a sciencein itself but the simultaneous and frequently coordinated activity of many in-dependent scientific disciplines, viz. clinical medicine, surgery, pathology, radia-tion physics, genetics, immunology, endocrinology, and biochemistry.... It isquite possible that the list of oncological sciences is not yet complete and thatsome new mode of approach not envisioned at the present time will be added inthe future." It is this complex intermingling of scientific activities necessitatedwhen life processes are under investigation that now makes the scientist's lotharder, and at the same time more enjoyable. Much time must be spent in un-ravelling what others have found out, and in building up a quasi-spatial picturethereby. To quote Greenstein4 again, "The bibliographer in the field of cancerresearch is confronted with a monstrous and amorphous literature, controver-sial, often hastily ambitious and frequently haunted by the ghosts of .. . oncehopeful and dazzling hypotheses." Every scientist is, or should be, his own bestbibliographer. No one can do for him a synthesis of knowledge encompassingjust those bits he lacked before, although the fragments can be uncovered andpresented to his view by others. He must make an effort himself to assimilate.In a discussion of abstracting in quite another sense, but which seems equallyappropriate when applied to abstract periodicals, Vogt5 says, "With our scienti-fic methods we have abstracted certain knowledge, but inevitably we left some-thing out. We cannot know all. Each person abstracting draws a different in-ference." I emphasize this point only because there seems to be a mountingtendency today to rely on the information in abstracts alone rather than to gotake down the original reference from the shelf and cope with its fuller detailpersonally. The latter step is important in preventing the introduction of fresherrors into our thinking, or the perpetuation of old ones. Abstracts are wonder-fully useful, but they are not, and do not claim to be, the basic scientific record.

ABSTRACTS AND INDEXES FOR CANCER LITERATURE

Whereas Greenstein4 spoke of the quality and survival value of cancer litera-ture, pathologists and cancer research workers have often complained that thereis no good cancer abstracting source. It is an attitude of mind engendered bythe need to supplement information from many different types of record. This

3Biochemistry of Cancer, N. Y., Academic Press, 1947, p. 1.4Loc. cit., p. 4.5"As Man Thinketh," . Heredity, 39: 166, 1948.

10

LITERATURE OF CHEMICAL PERIPHERY

situation obviously arises in large measure from the diversity of fields whichimpinge on cancer. The older zoological literature offers a counterpart. (Inpassing, reference should be made to an excellent synthesis in another interdis-ciplinary field, that by Hoff6 for submarine medicine.)Let us assume that the chemist has reaped the cancer harvest from Chemical

Abstracts and its current issues, with the primary site in Section 11 G, and scat-tered metastases through the remainder. Chemisches Zentralblatt will yield himlittle more. The first additional major abstract source is the Index AnalyticusCancerologiae. This French abstract quarterly usually will supply a wealth ofinformation or leads. Several new mimeographed abstract bulletins have beenstarted in the United States lately, of which Cancer Current Literature and Nleo-plastic Disease Abstracts have survived. They are quite helpful for locating re-cent literature, although the abstracts themselves are sometimes sketchy andresearch phases made subordinate. In time these bulletins may become evenmore helpful. The same may be said for Excerpta Medica struggling toget started. This splendidly conceived and executed, non-profit medical ab-stract journal deserves widespread support. It has not quite come abreast ofcurrent literature yet. In it the cancer literature not of a highly specializednature is concentrated in the "General Considerations" sub-division in SectionXIV, Radiology, although this journal, like Biological A bstracts, repeats ab-stracts in various sections rather than listing cross references at the end of sec-tions. The reason behind that practice is undoubtedly the sale of individualsections on a subscription basis.

Cancer information is scattered about in Biological Abstracts, so that on thewhole it is not an attractive source for current literature. Its annual indexes alsolag deplorably. The abstract section of Zeitschriftfiir Krebsforschung just resur-rected post-war with volume 56, number 1, April, 1948, can be most useful. Theold Zentralblatt der Krebskrankheiten is used only in a comprehensive historicalstudy or long-haul approach to cancer problems. Certainly the Q.C.I.M. is ofmuch more service in this connection. Because of the time lag in its appear-ance, however, it is of little value for current material and the Current List islikewise nearly useless because of its arrangement and its sporadic issuance ofindexes. These latter factors may be resolved in the near future.

Nutrition Abstracts is of some aid for literature on gastric cancer, diet in rela-tion to tumors, and on cell metabolism. Unless the problem at hand has a radia-tion aspect, the NVuclear Science Abstracts, issued by the Atomic Energy Com-mission's Oak Ridge National Laboratory (T.I.D.) with assistance from CrerarLibrary, is not helpful. This bulletin is otherwise recommended for its abstractsof M.D.D.C. and A.E.C.D. declassified reports.The abstract sections of several research periodicals such as the endocrino-

6E. B. Hoff, A Bibliographic Source Book of Compressed Air, Diving and Submarine Medicine.Washington, Bur. Med. and Surgery, Navy Dept., 1948.

11

HAROLD OATFIELD

logical and radiological journals should not be neglected for cancer data. Theyare particularly of value for the latest clinical procedures. Journals devoted ex-clusively to the primary subject naturally must be scanned.

REVIEWS AND ADVANCES

Among the various review sources I have listed, the Annual Review of Bio-chemistry has proved consistently beneficial. These concentrates, aside fromany critical function they may exercise, are unquestioned time-savers. A re-viewer has pointed out that the current volume (16) of the Annual Review ofBiochemistry reviews the work of over 4000 investigators. The A.A.A.S. con-ference monographs have an uneven quality, but are nonetheless stimulating.The usefulness of these various items obviously is modified by the nature of one'sown research interests. Those review sources listed under Subdivision 3. Reportsare less rewarding on the whole, but are not necessarily to be neglected, sincethey may indicate trends in research thinking. The Syllabus put out by ColonelAsh7 was planned for medical students and specialists, but it appears to offersome advantage also to cancer investigators not having a medical background.

PERIODICALS

It is a simple matter to mention good periodicals specializing in cancer. Pub-lished in English there are Cancer, Cancer Research, the Journal of the NationalCancer Institute and the British Journal of Cancer. Prewar German: Zeitschriftfiur Krebsforschung and Monatschrift fur Krebsbekampfung. Postwar: Krebsarzt.Others of note: Gann, Tumori, Voprosy Onkologie, Oncologia.When one progresses to journals which sometimes publish articles on cancer,

the flood-gates are opened to the 30,000 odd scientific periodicals of the WorldList, with all their variations in merit. All the biochemical, clinical, pathological,and surgical journals lie within the direct scope. Ewing8 prefixed to his classicbook a key of personal abbreviations for about 40 journals which he cited withgreat frequency, and his bibliographies further contain a wide range of othertitles as well. The lists of periodicals offered here have been drastically pruneddown. Perhaps, nevertheless, it would be well to mention the merits of Growth,Blood, Endocrinology, Experimental Medicine and Surgery, and the New EnglandJournal of Medicine to chemists seeking pertinent new browsing. Among foreignjournals the various Acta, but especially, Acta Physiologica Scandinavica andActa Radiologica, Arkiv for Kemi, Mineral och Geologi, Zeitschrift fur Zellfor-schung, the Comptes rendues des travaux de laboratoires de Carlsberg, both Serieschimique and Series Physiologique, and Chromosoma are suggested.

7J. E. Ash, Syllabus of Dermopatizology; Nevi and Neoplasnis. Course No. 3. Washington,Govt. Printing office, 1948.

8James Ewing, Neoplastic Diseases 4th ed. Phila., Saunders, 1940.

12

LITERATURE OF CHEEMICAL PERIPHERY

HANDBOOKS AND REFERENCE WORKS

In building up a personal background of modern cancer art, the chemistshould begin with Greenstein's book, progress to Ewing8 and perhaps dip intoWolff's treatise.9 Then he might approach one of the special sections on cancerin a "Handbook" selected for its relation to his individual research project, e.g.Heffter and Huebner10 if he is interested in carcinogenesis and chemotherapy.Henke-Lubarsch'1 can be recommended generally.The robust investigator can chart his own way through the book lists ap-

pended to this paper. Works of exceptional merit and broad interest have beenstarred.

Guided by these fresh blaze-marks, I hope that chemists can proceed to fighta speedier and happier battle through the forest of cancer literature to theirobjectives.

I. CancerA. ABSTRACTS AND INDEXES FOR LOCATING CANCER LITERATURE

1. Cancer Only1. Cancer Current Literature, a periodical annotated list (1947) +. Published by

the National Office of American Cancer Society, N.Y. Supplied gratis to physi-cians and qualified research workers. Attempts complete world coverage ofpublished research and clinical observations on cancer and closely relatedfields of investigation. Weaker on research side. Abstracts are classified by asystem based on the record system of Memorial Hospital, N.Y. and the subjectheading of the Q.C.I.M. Not quite up to date yet. Miss Hester A. Bradbury,ed. with cooperation of N. Y. Acad. of Medicine library.

2. Neoplastic Disease Abstracts, v. 1, No. 1, Nov. 11, 1946. Issued by LouisianaDivision Am. Cancer Society, New Orleans 13, La. (Miss Virginia Parker,Compiler, with cooperation of the Rudolph Matas Medical Library, TulaneUniversity). Has also issued Index to Current Periodical Literature in Neo-plastic Disease, Jan.-June 1947-n.d. no pagination.

3. Index Analyticus Cancerologiae (Paris) 1 (1927) +. Published quarterly byLigue Frangaise contre le cancer. Continuation of Rev. analytique de trav. surle cancer, which formed a part of the Bull. Assoc. Franc. pour l'Etude du cancerfrom 1922-1927. Abstracts of periodical lit. only.

gJacob Wolff, Die Lehre von der Krebskrankheit, Jena, Fischer, 1907-1928, 4 vols.10Heffter and Huebner, Handbuch der expermentalle Phzarmakologie. Berlin, Springer, 1923-

1934. (e.g. Section on Aromatische Kohlenwasserstuffe, Blei, usw.)"1F. Henke and 0. Lubarsch, Handbuchz der spezidllen pathologische Anatomie und Histologie.

12 v. in 27 parts. Berlin, Springer, 1925-1939. Various chapters, e. g.v. 1. pt. 2, Leukemia

4, pt. 1, Geschwulst der Magen und Magenveratzungen (Merkal)4, pt. 2, Entzuindlung des Magens4, pt. 3, Geschwulst des Darms5, pt. 1, Hyperplasie der Leber. Leber Parasiten6, pt. 2, Blasengeschwulste

10, Pathologische Ana tomie

13

HAROLD OATFIELD

4. Zentralblatt der Krebskrankheiten (Leipzig) 1-6 (1902-1910). v. 1-5 called"Karzinomalitteratur".

5. Cancer Review; a journal of abstracts (Bristol, Eng.), v. 1-7 (1926-1932). Classi-fied abstracts of the lit. on cancer research.

6. Index to the literature of experimental cancer research. Part I, 1900-1935, Mil-dred W. Schramm, Compiler. 334 pp. Baltimore, Lord Baltimore Press, 1936.An author index prepared for the International Cancer Research Foundation.

7. Review of Tumor Therapy, 1, Nos. 1-4 (1937), (Charleston, S. C.). Merged withSouthern Surgery.

8. The Pith of Recent Cancer Literature 1 (1943), Rochester, N. Y. (Issued by Am.Soc. for Control of Cancer).

2. Including Cancer9. Excerpta Medica, 1 (1947) + Section XIV Radiology. General Consideration,

contains cancer abstracts; Radiological Diagnosis; Radiotherapeutics; ab-stracts on clinical cancer.See also Section V. Gen. Path. and Path. Anat. III. Endocrinology II. Physi-ology, Biochemistry and Pharmacology I. Anatomy.

10. Quarterly Cumulative Index Medicus. (Chicago) 1 (1927) +11. Chemical Abstracts (Columbus, 0.) 1 (1906) +12. Biological Abstracts 1 (1926) +13. Physiological Abstracts 1-22 (1916-1937).14. Nutrition Abstracts 1 (1931) +15. Industrial Arts Index, 1 (1913) +16. Bibliographic Index, 1 (1938) +17. Zentralblatt fur Chirurgie, 1 (1874) Index v. 1-50 (resumed publication 1947)18. Zentralbl. f. allgem. Path. u. Path. Anat. 1890-(resumed publication 1947)19. Zentralbl. f. Gewerbehyg. (Berlin) 1-10 (1910-1922) n.s. 1 (1924)20. Zentralblatt f. Bakt., Parasitenk. Abt. I. Referate 1 (1887) +21. Abstracts of World Medicine, 1 (1947) +22. Exp. Sta. Record-Animal tumors, genetics. 1 (1889) +

3. A bstract Sections of Specialized Periodicals

23. Cancer, 1, No. 1 (July 1948) +24. Cancer Research (and predecessor Am. J. Cancer). 1 (1941) + Research Reports;

Clin. & Pathological Reports. Classed by body location.25. Zeit. f. Krebsforschung (Berlin) 1 (1903) +26. American Journal of Roentgenology. 1-5, 1906-13; ns v 1 (1913) +27. Radiology 1 (1923) +

Abstracts of current literature.I. Roentgen Diagnoses. Classified by systems

II. RadiotherapyIII. Radiation Effects

B. REVIEWS AND ADVANCES

1. Serial Reviews

Annual Review of BiochemistryAnnual Review of PhysiologyAdvances in Protein Chemistry

14


Advances in Biological and Medical PhysicsAdvances in EnzymologyCancer Review (see under A. Abstracts and Indexes)Nutrition ReviewsOmnia MedicaRecent Progress in Hormone ResearchRevue des Maladies Cancereuses (1895-1901), clinical, experimental and bibliog-

raphies.

2. SymposiaAAAS Monographs-"Research Conference on Cancer", Wash., D.C. AAAS Press,

1945; "Mammary Tumors in Mice". 1945; "Approaches to Tumor Chemotherapy".1947.

Cold Spring Harbor Symposia on Quantitative BiologySymposia of the Society for Experimental Biology

I "Nucleic Acid" edited by J. F. Danielli and R. Brown, Cambridge U. Press 1947.II. Growth in Relation to Differentiation and Morphogenesis (in press)

N. Y. Acad. of Science "Nutrition in Relation to Cancer", Ann. N. Y. Acad. Sci.,49, 1-140 (1941); "Biology of Melanomas", 1948; "Effect of Folic Acid Derivativeson Certain Types of Neoplastic Disease". Tr. N. Y. Acad. Sci. 10, 68-103 (1948)No. 3

3. ReportsAnnual Report British Empire Cancer Campaign 1907 +Annual Report British Cancer Research Fund (Sometimes referred to as Sci. Repts.

Imp. Cancer Research Fund, London). 43rd ed. (1945-1946).Report of the International Cancer Research Fund 1939 +Report of the International Conference on Cancer held in London 1928, Wright:

BristolReports and Transactions of the International Congresses Against Cancer (sponsoredby Union Internationals contre le Cancer)

3rd 1939, Atlantic City4th International Cancer Research Congress, St. Louis 1948

Annual Report of State Institute for Study of Malignant Diseases, New York Dept.Health.

Selected Papers from the Royal Cancer Hospital and the Chester Beatty ResearchInstitute. 2 vol., London 1939-1940.

4. Special TopicsJ. E. Ash, Syllabus of Dermopathology; Nevi and Neoplasms. Course No. 3. Complete

with slides. May be borrowed from Army Institute of Pathology for use in con-tinental U.S.A. The Institute also maintains 16 registries for various types oftumors.

British Medical Bulletin, 4, No 5./6 (1947) entire issue devoted to "Chemical Car-cinogenesis".

I. Cervini, Omnia Med., 26, 1-111 (1948)"Alimentazione e Tumori"

H. Holthusen and A. Vonessen, "Therapy of Malignant Cancer" FIAT Review ofGerman Science 1939-1946. Radiology volume, Section 12. Dieterich 'sch Verlag:Wiesbaden 1948.

is

16 HAROLD OATFIELD

D. A. Karnovsky, N. England J. Med., 239, 226-230, 260-270, 305 (1948) "Chemo-therapy of Neoplastic Disease".

I. T. Nathanson, Recent Progress in Hormone Res., 1 (1947) "Endocrine Aspects ofHuman Cancer".

Gilbert W. Beebe, "Expected Incidence of Certain Neoplastic Disease in Veterans".Committee on Vet. Med. Problems, N.R.C., Washington 1947.

Am. Med. Assn.-Am. Cancer Soc. Series on aid in early cancer diagnosis during 1948.No. 14. H. Martin, J. Am. Med. Assn. 137, 1306-1315 (1948) Aug. 7. "Cancer ofthe Head and Neck".

5. Selected Cancer BibliographiesPrescriber (Edinburgh) 30, 9 (1936) "Cancer". Annual bibliography for 1935Arq. pat. 8, 105-120 (1936) "Catalogo do Museo de oncologia" CXXX-CXXXVIIIndex analyt. cancer. 12, 459-487 (1938) "Histologie; physiologie; pathologie experi-

mentale et comparee".Ostertag, Med. Klin. (Berlin) 38, 278-281 (1942) "Krebsbekampfung; krebsbehand-

lung. Recent bibliog.H. Tecoz, Prasas (Bern) 33, 277-282 (1944) "Travaux recent en cancerologie".I. T. Nathanson, N. England J. Med., 227, 830-839 (1942) "Cancer" (recent bibliog.)Index to Current Periodical Lit. on Neoplastic Diseases and List of Current Books,

Jan.-June 1947, n.d. Louisiana State Div., American Cancer Society 1430 TulaneAvenue, New Orleans 13, La.

D. A. Karnovsky, N. England J. Med., 239, 226-230, 260-270, 305 (1948) "Chemo-therapy of Neoplastic Diseases".

C. PERIODICALS1. Journals Devoted to Cancer

Acta Cancrologica (Budapest) 1 (1934) suspended with 3, No. 1 (1937)Acta Cancerologica Jugoslav. 1 (1939)Acta Radiologica et Cancerologica Bohemoslovenica, (Prague) 1 (1938) No. 1/2Acta Unio Internat. Contra Cancer (Paris) 1 (1936) (Contrib. in English, Fr., Ger.

Ital., and Russian)American J. Cancer, 1940, v. 1-40; 1916-1940 discontinued with v. 40. No. 4, Dec.

1940. Succeeded by Cancer Research.Archives of Clinical Cancer Research (N. Y.), v. 1-5 (1925-1930)Arch. Cubanos de Cancerologia (Inst. of Radium, Havana) 1 (1942) +Bol. del Inst. de med. exper. para el estudie y trat. del cancer (Buenos Aires) v. 1

(1924) +Bol. de. Inst. radiol. cancer (Montevideo) Instituto de radiologia y Centro de estudioy lucha contra el cancer. Boletu v. 1 (1931)+

Bol. de la Liga contra Lutte Cancer (Havana) (Edicion Cientifica, 1 (1926) +(Edicion Social

Bo!l. Lega Ital. Cancero, 1936, no vol.-Rassegna di Oncologia v. 1 (1927) +British Journal of Cancer, 1 (1947) +Bull. Am. Cancer SocietyBull. Am. Soc. for Control of Cancer-No. 1-5, 1917; n. 6. v 1 (1918)+Bull. de l'Asso. francaise pour l'Etude du Cancer (Paris) irr. 33 (1946) 37th year

26 (1937), 28 (1939), 29 (1940-1941).-v. 1 (1908)+Bull. Koch Cancer Clinic (Detroit) v. 1-5 (1926-1932). Of very dubious merit in

view of Koch's career. v. 4 appears as Journal of Cancer and Allied Diseases. Allin one no.


Bull. Soc. belge de cancerol (Brussels). Q. Published in association with "Le Cancer".Suspended with v. 13, No. 1, Jan. 1937.

Cancer (Philadelphia) v. 1-5 1923-1928 (Am. Assn. for study and cure of Cancer).Cancer (Santiago de Chile) v. 1 (1930) +Cancer (Edinburgh) v. 1 (1934) + (Cancer Control Org. for S.E. Scotland)Cancer; international monatsschrift (Berlin) v. 1-6, No. & (1908-1914)(Le) Cancer, v. 1 (1923-1937), (Revue international d'etudes cancerologiques).Suspended with 13, No. 1 (Jan. 1937).

Cancer (Toronto) 1 (1939) + (Canadian Soc. for Control of Cancer).Cancer, 1 (1948) No. 1, July (Am. Cancer Society: N.Y.)Cancer Digest of America (Indianapolis) v. 1-37 (1898-1934). This title began 1915,

earlier volumes published as Med. and Surgical Monitor.Cancerforingen (Stockholm) (1913-1938)Cancer Research (Am. Assoc. for Cancer Research) v. 1 (1941) +Cancro, 2 (1931) (Turin)-1-5, 1930-1934.Carcinomologische Studien (Berne) 1 (1937) +Columbia U. Studies in Cancer, v. 1-4, (George Crocker special research fund.) v.

1-4, 1912-13.Gann (Japanese J. Cancer Research (Tokyo) 1 (1907) bi-m. 35 (1941) (Text in English,German and Japanese).

Journal of Cancer (London) (1913-1922). Volumes for 1913-1919 appeared as J.Soc. for Prevention of Cancer.

Journal of Cancer (Dublin) 1-3 (1924-1926)Journal of Cancer and Allied Diseases. See Bull. Koch Cancer ClinicJournal of Cancer Research, 1 (1917) Name changed with v. 15, No. 1 (Jan. 1931) toAm. J. Cancer

Journal Cancer Research Comm. Univ. Sydney (New South Wales) ceased publica-tion with v. 8, No. 3/4, Oct. 1938.-1-8, 1929-1938

Journal of the National Cancer Inst., v. 1 (1940)+Krebsartzt, v. 1 (1946) +Monatsschrift fur Krebsbekampfung (Munich) 1 (1933), 9 (1941).Neoplasmes, v. 1 (1922). Discontinued with 14, No. 6 (Nov.-Dec. 1935).Nowatwory (Warsaw) 1 (1923) (English tr. of title: Neoplasms)Oncologia (Basel) 1 (1948)Rev. Liga puertorriq. contra el Cancer (Puerto Rico) 1 (1941)Rev. med. y cancerologia (Santa Fe) 1 (1927) +Revista Mexicana de Cirugia Ginecologia y cancer, Mexico, 1 (1933) +Tumori (Rome) 1 (1911) new series 1 (1923)Unio Internationalis Contra Cancrum Acta, (Belgium) 3 (1938), 4 (1939). Probablysame as Acta Unio Internat. Contra Cancer-v. 1 (1946) +

Voprosy Onkologie (Kharkov) 1-10 (1926-1936) (Engl. tr. of title: Problems of On-cology).

Ztschr. fur Krebsforschung (Berlin) 1 (1903)

2. American Journals Frequently Carrying Articles on Cancer

American J. Med. Sci. 1-26, 1927-40; nsv 1 (1941) +American J. Ophthalmology 1-34, 1884-1917; 53 v. 1,(1918) +American J. Pathology 1 (1925) +American J. Physiology 1 (1898) +American J. Public Health I (1911) +American J. Roentgenology 1-5, 1906-13; Iisv 1, 1913+

17

HAROLD OATFIELD

Anatomical Record 1 (1906) +Annals of Internal Medicine 1 (1927) +Annals of the N. Y. Acad. Sci. 1 (1877) +Archives of Biochemistry 1 (1942) +Arch. Derm. and Syphilology 1 (1920) +Arch. Path. 1 (1926)+Blood 1 (1946) +Bull. Hosp. Joint Diseases 1 (1940) +Bull. Johns Hopkins Hosp. 1 (1889) +Bull. N. Y. Acad. Med. 1-4, 1860-71; 52 v. 1, (1925)+Endocrinology 1 (1917) +Federation Proceedings 1 (1942) +Growth 1 (1937) +Journal Am. Med. Association 1 (1883) +Journal of Clinical Investigation 1 (1924) +Journal of Experimental Medicine 1 (1896) +Journal of General Physiology 1 (1918) +Journal of Heredity 1 (1910) +Journal of Heredity 1 (1910) +Journal of Laboratory and Clinical Med. 1 (1915) +Med. Woman's Journal 1 (1893) +New England Journal of Med. 1 (1828) +Proc. Soc. Experimental Biol. & Med. 1 (1903-04) +Proc. Staff Meeting Mayo Clinic 1 (1926) +Radiology 1 (1923) +Science 1-23, 1883-1894; nsv 1, 1895+Southern Surgeon 1 (1932) +Surgery 1 (1937) +Surgery, Gynecology and Obstetrics 1 (1905) +Urologic and Cutaneous Rev. 1 (1897) +Yale Journal Biol. & Med. 1 (1928) +

3. Foreign Journals Frequently Carrying Articles on CancerActa Medica (Rio de Janeiro) 1 (1938) +Acta Med. U.R.S.S. 1 (1938)+Acta Path. et Microbiol. Scand. 1 (1924) +Acta Radiologica (Stockholm) 1 (1921) +Ann. d'anat. path. 1 (1924) +Arch. di Radiologia (Naples) 1 (1925) +Arch. f. Gynaek. 1 (1870)+Arch. f. Path.Arch. Path. Anat. Virchows 1 (1847)Arch. Klin. Med. Deutsches 1 (1865)Arch. Sci. Biol. U.S.S.R.-Arkhiv biol. nauk 1 (1892) +Ark. Kemi Minerol o. Geol. 1 (1903/04) +Biochemical Journal 1 (1906) +Biochemische Zeitschrift 1 (1906) +Brit. J. Exptl. Path. 1 (1920) +Brit. J. Radiology 1 (1928) +Brit. J. Surgery (Bristol) 1 (1913) +Brit. Med. Bull 1 (1943) +Brit. Med. J. (London) 1 (1857) +

18


Casop. lek cesk (Prague) 1 (1862) +Compt. rend. soc. biol. 1 (1849) +Dia Med. (Buenos Aires) 1 (1928) +Edinburgh Med. J. 1-42, 1855-96; nsv 1-23, 1897-1908; nss 3 r 1, 1908 +Folia clin. et biol. (Sao Paulo) 1 (1929) +Journal of Hygiene (Cambridge, England) 1 (1901) +Journal Obstet. & Gyn. Br. Empire (Manches.) 1 (1902) +Journal Path. and Bact. 1 (1892) +Miinchen Med. Wchnschr. 1 (1854) +New Zealand Med. Journal 1-9, 1887-96; nsv 1, 1900+Pasteur (Mexico) 1 (1928) +Pathologica 1 (1908) +Praxis (Berne) 1-23, 1909-23; nsv 12, 1923 +Prensa Med. MexicoPresse Med. 1 (1893) +Proc. Royal Soc. Med. 1 (1907) +Rev. med. de Chile (Santiago) 1 (1872) +Rev. radiol. y fisioterap. 1 (1934) +Roentgenpraxis (Leipsig) 1 (1929) +Schweiz. Med. Wchnschr. (Basel) 1 (1870) +Semana Med. (Buenos Aires) 1 (1894) +Soviet klin. 1-21, 1924-35Soviet vrach zhur. (Leningrad) 1894-1935Strahlentherapie-Originale, 1 (1912) +Trans. Jap. Path. Soc. 1 (1911) +Wien. Klin. Wchnschr. 1 (1888) +Z. f. d. ges. exp. Med. 1 (1913) +Z. Physiol. Chem. 1 (1887) +Z. f. Zellforschung 1 (1924) +

D. HANDBOOKS AND MONOGRAPHS

1. Handbooks and Reference Works on CancerJACOB WOLFF, "Die Lehre von der Krebskrankheit, Jena: G. Fischer 1907-1928, 4

volumes. Exhaustive study for the time.JAMES EWING, "Neoplastic Diseases" 4th ed 1940, Phila: Saunders. Classic mono-

graph.JESSE P. GREENSTEIN, "Biochemistry of Cancer". Academic Press 1947. Excellent

critical review written principally for the chemist and biologist rather than theclinician. Particularly stimulating discussion of chemotherapy and biochemistryaspects and insights into research problems.

G. T. PACK AND E. M. LIVINGSTON, "Treatment of Cancer and Allied Diseases". 3vol. Harper 1940. Sound.

C. ADAm AND H. AULER, "Neuere Ergebnisse auf dem Gebiete der Krebskrankheiten".Hirzel: Leipzig 1937.

M. BORST, "Die Lehre von dem Geschwulsten". 2 v. Wiesbaden 1902. Historical.ROBT. BEHLA, "Die Carcinomalitteratur", Berlin 1901. A compilation of early cancer

journals.

2. Specific Sections on Cancer in General HandbooksH. BETHE, "Handbuch der norm. u. path. Physiol.", section by B. Fischer-Wasels

v. 14, p. 1941. Springer: Berlin 1927.

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HAROLD OATFIELD

0. BUMKE AND 0. ROERSTER, "Handbuch der Neurologie", 1936. Section by 0. Mar-burg, v. 11, Spezielb. Neurologie III, pt. 1 Hirngeschwulste.

H. DOWNEY, "Handbook of Hematology", 4 v. Hoeber: N. Y. 1938. e.g. Polycythemia;Action of Radiation on Blood-forming Tissues, etc.

HEFFTER AND HUEBNER, "Handbuch der exp. Pharmakologie", Springer: Berlin1923-1934, e.g. Section on Aromatische Kohlenwasserstuffe, Blei, usw.

F. HENKE AND O. LUBARSCH, "Handbuch der spez. path. Anatomie u. Histologie".12 v. in 27 parts. Springer: Berlin, 1925-1939. Various chapters. e.g.

v. 1, pt. 2, Leukemia4, pt. 1, Geschwulst der Magen u. Magenveratzungen (Merkal)4, pt. 2, Entziindung des Magens4, pt. 3, Geschwulst des Darms5, pt. 1, Hyperplasie der Leber. Leber Parasiten6, pt. 2, Blasengeschwulste10 Path. Anatomie

JADASSOHN, "Handbuch der Haut u. Geschlechtskrankheiten". Springer, Berlin1928-1932. Various phases.

H. LINIGER, R. WEICHBROD AND A. W. FISCHER, "Handbuch der Artzlichen Begut-achtung". Barth: Leipzig 1931. e.g. v. 1 Tumoren (by B. Fischer-Wasels). Krank-heiten der Blutes.

Loose Leaf Medicine SeriesA. Oxford MedicineB. Tice, "Practice of Medicine". Prior (Hagerstown)C. Nelson Loose Leaf Medicine

OSLER, "Modern Medicine". Lea 1940 Chapter by Harvey Cushing "IntracranialTumors".

H. A. REnuAN, "Treatment in General Practice". Davis, 1946, Chapter on "Cancer"by S. P. Reimann

3. American Books on Cancer

*LAUREN V. ACKERMAN AND JUAN A. DEL REGATO, "Cancer; Diagnosis, Treatmentand Prognosis". Mosby 1947.

MARIAN E. ANDERSON, "Study of Cancer of the Breast and Uterus". FranklinPress 1938.

ANGERINE AND ASH, "Atlas of Orthopedic Surgery". S.G.O. Army Medical Museum:(Washington) 1943.

P. BALEY AND H. CUSHING, "Tumors of the Glioma Group". Lippincott 1926G. BARZILAI, "Atlas of Ovarian Tumors". Grune and Stratton 1943R. J. BEHAN, "Cancer, with special reference to cancer of the breast". Mosby 1938

ibid, "Relation of Trauma to New Growth". Williams & Wilkins 1939A. BRAUNSTEIN, "Problem of Prophylaxis of Cancer from the Immuno-biological

Standpoint".ALEX. BRUNSCHWIG, "Surgery of Pancreatic Tumors". Mosby 1942

*S. CADE, "Malignant Disease and Its Treatment by Radium". Wood 1940FLOYD E. CHIDESTER, "Nutrition and Glands in Relation to Cancer". Lee Foundation

for Nutrition Research 1944.

* Especially important.

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H. W. CUSHING AND L. EISENHARDT, "Meningiomas, Their Classification, RegionalBehavior, Life History and Surgical End Results". Thomas 1938

*VILRAY P. BLAIR, S. MOORE AND L. T. BYERS, "Cancer of the Face and Mouth:Diagnosis, Treatment, Surgical Repair". Mosby 1947

*HAROLD W. DARGEON (ed.) "Cancer in Childhood". Mosby 1940Louis I. DUBLIN AND A. J. LOTKA, "Mortality from Cancer". Metropolitan Life

Ins. Co.: (N. Y.) 1938*JAMES EWING, "Neoplastic Diseases", 4th ed. Saunders 1940L. E. FIESER, "Cause and Growth of Cancer". U. Penn. Press 1940*NATHAN FOOT, "Identification of Tumors". Lippincott 1948*C. E. FORKNER, "Leukemia and Allied Diseases". Macmillan 1938CHAS. F. GESCHICKTER, "Diseases of the Breast". 2nd ed. Lippincott 1945CHAS. F. GESCHICKTER AND M. M. COPELAND, "Tumors of Bone". Am. J. Cancer

Press: N. Y. 1936 (o.p.)T. J. GLOVER, et al, "Studies in Malignancy". Murdock Foundation 1940ibid "Treatment of Cancer in Man". Murdock Foundation 1938*JESSE P. GREENSTEIN, "Biochemistry of Cancer". Academic Press 1947*J. L. HARTWELL, "Survey of Compounds which have been Tested for Carcinogenic

Activity" U.S.P.H.S. Bull. 1941F. L. HOFFMAN, "Cancer and Diet". Williams & Wilkins 1937*W. C. HUEPER, "Occupational Tumors and Allied Diseases". Thomas 1942*CHEV. AND CHEV. L. JACKSON, "Cancer of the Larynx". Saunders 1939HELEN T. KONJIAS (ed.), "Manual of the M.D. Anderson Hospital for Cancer Re-

search". (Houston) 1945ERIC LILJENKRANTZ, "Cancer Handbook of theTumor Clinic". Stanford U. Press 1939EDW. M. LIVINGSTON AND G. T. PACK, "End Results in the Treatment of Gastric

Cancer". Hoeber 1939PERRY NICHOLS, "The Value of Escharotics". 1944GEO. T. PACK, "Tumors of the Hands and Feet". Mosby 1940*G. T. PACK AND E. M. LIVINGSTON, "Treatment of Cancer and Allied Diseases".

3 vols. Harper 1940*GEO. N. PAPANICOLAOU, H. F. TRAUT AND A. A. MARCHETTI, "Epithelioma of

Woman's Reproductive Tract". Commonwealth Fund: N. Y. 1948E. PODOLSKY, "The War on Cancer". Reinhold 1943FRED W. RANKIN AND A. E. GRAHAm, "Cancer of the Colon and Rectum". Thomas

1940*PEYTON Rous, "Virus Tumors and The Tumor Problem". Harvey Lectures, 31 (1935)GREG. SCHWARTZMAN, "The Pheomenon of Local Tissue Reactivity and Its Im-

munological, Pathological and Clinical Significance". Hoeber 1937D. W. SMITHERS, "X-Ray Treatment of Accessible Cancer". Williams & Wilkins 1946KUTRT STERN AND R. WILLHEIM, "Biochemistry of Malignant Tumors". Chem.

Publishing Co. 1943T. A. F. STONE, "Cancer" (New Zealand) 1940A. STOUT, "Human Cancer; Etiological Factors; Precancerous Lesions". Lea 1932*G. W. TAYLOR AND I. T. NATHANSON, "Lymph Node Metastases; Incidence and

Surgical Treatment in Neoplastic Disease". Oxford 1942*TWOMBLEY AND PACK (See under Symposia)*W. WALTERS, HOWARD K. GRAY AND JAMES T. PRIESTLEY, "Carcinoma and Other

Malignant Lesions of the Stomach". Saunders 1942

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HAROLD OATFIELD

4. European Books on CancerJ. BAIO AND B. KORPASSY, "Warzen, Papillome u. Krebs". Barth: Leipzig 1936W. G. BARN AND A. H. T. ROBB-SMITH, "Kettle's Pathology of Tumors", 3rd ed.

Lewis: London 1945J. BATORY, "Novi progledi na problematiku carcinoma (Jugoslavia 1940)A. E. BLACKBURN, "Cancer; causation, prevention and treatment". Lewis 1939D. BROWNLIE, "Cause of Cancer". Chapman 1938T. CASPERSSON AND L. SANTESSIN, "Studies on Protein Metabolism in the Cells of

Epithelial Tumors". (Stockholm) 1942W. CASPARI, "Nutrition et Cancer", Hermann: Paris 1938PIERRE DELBERT, "Critique preventive du Cancer". 1944H. v. EULER AND B. SKARZYNSKI, "Biochemie des Tumores". Enke: Stuttgart 1942

(Italian ed. "Einardi": Turin (1945). Reference citations inadequate.E. FENSTER, "Tumor u. Unfalle Vortrage aus der prakt. Chirurgie". 14th ed. Enke:

Stuttgart 1947.C. FERNANDEZ-RuIz, "El Cancer de la Mujer". Madrid 19430. C. GRUNER, "Study of Blood in Cancer", Renouf 1942

*S. A. HENRY, "Cancer of the Scrotum in Relation to Occupation". Oxford 1946ELIz. Hurdon, "Cancer of the Uterus". Oxford 1942LEON IMBERT, "Cancerologie et pratique". 1943A. KLINGBACHER, "Ueber Entstehung, Entwickelung u. Heilungmoeglichkeit der

Krebsleiden". Bargezzi: Berne 1943FR. KOENIG AND E. SEIFFERT, "Wesen, Erkennung u. Behandlung der Krebs Krank-

heit". Enke: Stuttgart 1937J. KORBLER, "Klinische Krebsprobleme". Lehmann 1940*A. LACASSAGNE, "Actualities scientifiques et industrielles".

4. "Les cancer products par les rayonnements electromaquetic. Comprehensiveshort review of clinical and experimental data concerning carcinogenic actionof radiation, but of necessity ignores work of previous 5 years. Hermann: Paris1945

ibid "Radiophysiologie experimental Cancer et Hormones".5. Les cancer produits par les substances chimique exogenes". Masson: Paris 1946

ibid6. Etude de la cancerization par les substances chimiques exogenes". Hermann:

Paris 1947C. OBERLING, "The Riddle of Cancer". tr. by Wm. H. Woglom, Yale U. Press 1944OLIVER (ed.) "Cancer research memoirs; cancer control organization for Scotland".Edinburgh 1944

RALSTON PATERSON, "Treatment of Malignant Disease by Radium and X-Rays".London 1948

WM. RIENHOFF, "Principles and Foibles of Cancer Research". Waverly Press 1936(Ger. ed. "Aesculap Verlag": Wien 1936)

BROR SYLVEN, "Ester Sulfuric Acids of High Molecular Weight and Mast Cells inMesenchymal Tumors". (Stockholm) 1945

J. C. TIHomPSON, "New Approach to Cancer". Thorsons 1938H. TRUTTWEIN, "Medizin, Chemie and Krebs". Maudrich 1942*O. WARBURG, "Ueber der Stoffwechsel der Tumoren". Springer: Berlin 1926 (Eng-

lish ed. Constable: London 1930)*RUPERT A. WILLIS, "Spread of Tumors in the Human Body". Mosby 1934*R. A. WILLIS, "Pathology of Tumors". Mosby 1948

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literature of the chemical periphery i. cancer

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