LIQUID ORALS

PRESENTED BY-

ANWAR MUNJEWAR

M.PHARM(QUALITY ASSURANCE TECHNIQUES)

ALLANA COLLEGE OF PHARMACY, PUNE-01

CONTENTS:

INTRODUCTION METHOD OF PREPARATION PROCESSING FLOW CHART FACILITY DESIGN DESIGN ASPECTS MAN POWER REQUIRMENT LAYOUT

INTRODUCTION

Preparation in Liquid forms either clear solutions, suspension or emulsions.

Sugar Syrup – Base or Vehicle in Medicament.

Ingredients Used – Colours, Flavours, Preservatives etc.

GENERAL METHOD OF PREPARATION

Preparation of Sugar Syrup with preservatives.

Addition of other ingredients and dissolving; medicinal substance and colour.

Cooled up to 35° C. Addition of Flavour. Volume make as per the design. Flittered and finished product is stored

PROCESSING FLOW CHART

Day StoreLiquid

Preparation

Bottle Washing

Bottle Filling and

SealingInspectionLabelling

Packaging In-process Storage

FACILITY DESIGN

FOR SMALL SCALE : 3000Lit/shift or 30,000 bottles/shift

1500kg sugar + other material per shift

1 Batch of 3000Lit/shift

Equipment Details Weighing Balance

Sifter

Mfg. Vessels for syrup

Storage vessels

Bottle washing, sealing and labelling machine

Conveyor belts

DESIGN ASPECTSSTANDARD LAYOUT FOR LIQUID ORALS

MAN POWER REQUIRMENTS

Sr. No.

Name of Work Station

Large Scale

Small Scale

1. Day Store 2 1

2. Liquid preparation room

4 1

3. Bottle Cleaning 4(2x2) 2

4. Bottle filling & sealing

4(2x2) 2

5. Bottle Inspection 4(2x2) 1

6. Bottle Recovery 2(1x2) 1

7. Bottle Labelling 2(1x2) 1

8. Online Packaging 20(10x2) 6

Total 44 15

No. Of Persons

LAYOUT TYPICAL LAYOUT FOR SINGLE LINE LIQUID ORALS

DEPARTMENT

THANK YOU !