lipoprotein metabolism lecture for 2nd year mbbs by dr sadia haroon

8/14/2019 Lipoprotein Metabolism Lecture for 2nd year MBBS by Dr Sadia Haroon

1/99

Ck~g~tgxike lixmdgckql

D{

HT%QMHKM BMTGGEHI^MTXLIEX GJ DKGABILKQXT[


2/99

Ck~g~tgxikeq

~mtxkaciq jgyeh ke ~cmqlm xbmx xtmeq~gtxck~khq keacyhkef abgciqxitgc

ck~g~tgxike acmqqiq ab{cglkatgeq0 xmoi ck~khq jtgl qlmcc kexiqxkei

xbtgyfb c{l~b aiccq

zit{ cgv hieqkx{ ck~g~tgxikeq "ZCHC+

kexitlihkmxi hieqkx{ ck~g~tgxikeq "KHC+ cgv hieqkx{ ck~g~tgxikeq "CHC+

bkfb hieqkx{ ck~g~tgxikeq "BHC+


3/99

Ck~g~tgxikeacmqq

Hieqkx{"f'lC+

Hkmlixit "el+ ^tgxike ) gjht{ vx

^bgq~bgck~kh )

Xtkma{cfc{aitgc )gj ht{ vx

BHC =%>:1,=%4= 9 =9 11 4; 2

CHC =%>=; =%>:1 =2 42 49 4= 8

KHC =%>>:,=%>=; 49 , 9> =2 44 1=

ZCHC >%;9 =%>>: 1> , 2> => =2 9>

ab{cglkatgeq 3 >%;9 =>> , 9>> = , 4 6 28

Agl~gqkxkge meh ~tg~itxkiq gj bylme ck~g~tgxikeq

lgqx ~tgxikeq bmzi hieqkxkiq gj mdgyx =%1 =%8 f'lC meh ck~kh mfftifmxiq yqymcc{

bmzi hieqkxkiq gj mdgyx >%2 f'lC


4/99

Ck~g~tgxike qxtyaxyti


5/99

CHC lgciayci


6/99

Xbi m~gck~g~tgxikeq

lm`gt agl~geiexq gj ck~g~tgxikeq

gjxie tijittih xg mq m~tgxikeq

acmqqkjkih d{ mc~bmdixkamc hiqkfemxkge "M xbtyI+

xbi yqi gj tglme eylitmc qyjjkr hiqatkdiq xbigthit ke vbkab xbi m~gck~g~tgxike ilitfi jtgl

m abtglmxgftm~bka agcyle tiq~geqkdci jgt tiagfekxkge gj ~mtxkaci d{

tiai~xgtq


7/99

BICKAMC VBIIC ^TG@IAXKGE GJ M

^GTXKGE GJ M^GCK^G^TGXIKE M,K


8/99

CK^G^TGXIKEQ

q~bitkamc ~mtxkaciq vkxb m b{htg~bgdka

agti "XF meh iqxitkjkih abgciqxitgc+

m~gck~g~tgxikeq ge xbi qytjmai cmtfi0 m~gD "d,82 meh D,=>>+ mxbitgfieka

qlmccit0 m~gM,K# m~gA,KK# m~gI

acmqqkjkih ge xbi dmqkq gj hieqkx{ mehiciaxtg~bgtixka lgdkckx{ "ZCHC? CHC?

KHC?BHC? C~"m+


9/99

M~g~tgxikeq gj bylme

ck~g~tgxikeq M,K "42#1>>+, ~tkeak~mc ~tgxike ke BHC

;> =4> lf) ke ~cmqlm? maxkzmxiq CAMX

M,KK "2#6>>+ gaaytq mq hklit lmkec{ ke BHC 1> 9> lf )? iebmeaiq bi~mxka ck~mqi maxkzkx{

D,82 "48>#>>>+ jgyeh gec{ ke ab{cglkatge 39 lf )? hitkzih jtgl m~g,D,=>> fiei d{ TEM

ihkxkef? cmaoq xbi CHC tiai~xgt,dkehkef hglmke gjm~g,D,=>>

D,=>> "9>>#>>>+ ~tkeak~mc ~tgxike ke CHC 2> =>> lf )? dkehq xg CHC tiai~xgt


10/99

A,K "6#>>>+ jgyeh ke ab{cglkatge# ZCHC# BHC 8 6 lf )? lm{ mcqg maxkzmxi CAMX

A,KK "2#2>>+ , jgyeh ke ab{cglkatge# ZCHC# BHC 1 2 lf )? maxkzmxiq ck~g~tgxike ck~mqi

A,KKK "2#2>>+ , jgyeh ke ab{cglkatge# ZCHC# KHC# BHC 2 =9 lf )? kebkdkxq ck~g~tgxike ck~mqi

H "14#9>>+ , jgyeh ke BHC 2 => lf )? mcqg amccih abgciqxitgc iqxit xtmeqjit ~tgxike "AIX^+

I "18#=>>+ , jgyeh ke ab{cglkatge# ZCHC# KHC BHC 1 : lf )? dkehq xg CHC tiai~xgt

B "9>#>>>+ jgyeh ke ab{cglkatge? mcqg oegve mq ,4,fc{ag~tgxikeK "kezgczih ke XF lixmdgckql+

M~g~tgxikeq gj bylme

ck~g~tgxikeq


11/99

Lm`gt ck~g~tgxike acmqqiq

Ab{cglkatgeq "hitkzih jtgl hkix+

hieqkx{ 33=%>>:

hkmlixit 2> , 9>> el

hkixmt{ xtkfc{aitkhiq

m~gD,82# m~gM,K# m~gM,KK# m~gM,KZ# m~gA,

KK'A,KKK# m~gItilmkeq mx gtkfke ke iciaxtg~bgtixka jkich


12/99

Ab{cglkatge

jgtlih xbtgyfb irxtyqkge gj tiq{exbiqkpihxtkfc{aitkhiq jtgl xbi lyagqmc aiccq kexg xbikexiqxkemc cmaximcq

jcgv xbtgyfb xbi xbgtmaka hyaxq kexg xbiqyacmzkme zikeq

hiftmhih xg tilemexq d{ xbi maxkge gjck~g~tgxike ck~mqi "C~C+ vbkab kq cgamxih ge

am~kccmt{ iehgxbickmc aicc qytjmai tilemexq mti xmoie y~ d{ ckzit ~mtieab{lmc

aiccq hyi xg m~gI,KKK meh m~gI,KZ kqgjgtltiagfekxkge qkxiq


13/99

A

b{

cgl

katge

lixm

dg

c kql


14/99


ZCHC

hieqkx{ 5=%>>:

hkmlixit 1> , 2>eliehgfiegyq xtkfc{aitkhiq

m~gD,=>># m~gI# m~gA,KK'A,KKK

~tidixm ke iciaxtg~bgtiqkq

jgtlih ke xbi ckzit mq emqaiex ZCHC "agexmkeq gec{

xtkfc{aitkhiq# m~gI meh m~gD+


15/99

ZCHC

emqaiex ZCHCq xbie kexitmax vkxb BHCxg fieitmxi lmxyti ZCHCq "vkxb mhhih

abgciqxitgc# m~gA,KK meh m~gA,KKK+ lmxyti ZCHCq mti maxih y~ge d{ C~C xg

fieitmxi ZCHC tilemexq "KHC+

KHC mti jytxbit hiftmhih d{ bi~mxkaxtkfc{aitkhi ck~mqi "BXFC+ xg fieitmxiCHCq

Z


16/99

ZCHCl

ixmdgckq l


17/99


KHC "kexitlihkmxi hieqkx{ ck~g~tgxikeq+

hieqkx{0 =%>>: , =%>=;

hkmlixit0 49 , 19el

abgciqxit{c iqxitq meh xtkfc{aitkhiq

m~gD,=>># m~gI# m~gA,KK'A,KKK

qcgv ~ti,dixm


18/99


CHC "cgv hieqkx{ ck~g~tgxikeq+

hieqkx{0 =%>=; , =%>:1

hkmlixit0 =2,49el

abgciqxit{c iqxitq

m~gD,=>>

dixm "iciaxtg~bgtiqkq+

3 =1> CHC abgciqxitgc kq hiqktmdci# =1>,=9;

kq dgthitckei bkfb meh 5=:> kq bkfb


19/99


BHC "bkfb hieqkx{ ck~g~tgxikeq+

hieqkx{0 =%>:1,=%4=>

hkmlixit0 9,=4el

abgciqxit{c iqxitq meh ~bgq~bgck~khq

m~gM,K# m~gM,KK# m~gA,KK'A,KKK meh m~gI

mc~bm "iciaxtg~bgtiqkq+


20/99

BHCq

Qizitmc qydjmlkckiq irkqx

Hkqagkhmc BHC 0

agexmkeq abgciqxitgc# ~bgq~bgck~kh# m~gM,K# m~gM,KK# m~gI meh kq hkqa qbm~ih?

kx kq jgtlih ke ckzit meh kexiqxkei

Kx kexitmaxq vkxb ab{cglkatm tilemexq meh

ciakxbke,abgciqxitgc ma{c xtmeqjitmqi "CAMX+ xgjgtl BHC1


21/99

BHCq

BHC1

agl~gqih gj abgciqxitgc# abgciqxitgc iqxit# ~bgq~bgck~kh

meh m~gM meh m~gI

kexitmaxq vkxb xbi aicc ~cmqlm lildtmeiq xg tilgzi jtiiabgciqxitgc

timaxkge vkxb CAMX agezitxq BHC1xg BHC

4m"me BHC vkxb

m bkfb m~gI meh abgciqxitgc iqxit agexiex+

abgciqxitgc iqxit,tkab BHC4m

kq xbie agezitxih xg

xtkfc{aitkhi,tkab BHC4dd{ ageaglkxmex xtmeqjit gj BHC

abgciqxitgc iqxitq xg ZCHC meh ZCHC xtkfc{aitkhiq xg

BHC


22/99

BHC

lix

md

gckql


23/99

Jyeaxkgeq gj BHC

xtmeqjitq ~tgxikeq xg gxbit ck~g~tgxikeq

~kaoq y~ ck~khq jtgl gxbit ck~g~tgxikeq

~kaoq y~ abgciqxitgc jtgl aicc lildtmeiq

agezitxq abgciqxitgc xg abgciqxitgc iqxitq zkm xbi

CAMX timaxkge

xtmeqjitq abgciqxitgc iqxitq xg gxbitck~g~tgxikeq# vbkab xtmeq~gtx xbil xg xbi ckzit

"tijittih xg mq tizitqi abgciqxitgc xtmeq~gtx+


24/99

Ck~g~tgxikeq "m+, C~"m+

megxbit mxbitgfieka jmlkc{ gj ck~g~tgxikeq"mxcimqx =; hkjjitiex mcciciq+

xbi{ ageqkqx gj CHC meh m ~tgxike hiqkfemxih mq

"m+ xbi m~gM kq agzmciexc{ ckeoih xg m~gD,=>> d{ m

hkqycjkhi ckeomfi yeyqymc ke xbmx kx agexmkeq m otkefci ~tgxike

lgxkj'hglmke "xtk,cgg~ih qxtyaxyti vkxb 1

kextmlgciaycmt hkqycjkhi dgehq tiqildckef mHmekqb ~tixpic+

bkfb tkqo mqqgakmxkge vkxb ~tilmxyti agtgemt{mtxit{ hkqimqi meh qxtgoi


25/99

Abgciqxitgc meh ck~kh xtmeq~gtx d{

ck~g~tgxikeq


26/99

Abgciqxitgc meh ck~kh xtmeq~gtx d{

ck~g~tgxikeq


27/99


28/99


29/99

Xbi CHC tiai~xgt

abmtmaxitkpih d{ Lkabmic Dtgve meh @gqi~bFgchqxike "Egdic ~tkpi vkeeitq ke =;29+

dmqih ge vgto ge jmlkckmc b{~itabgciqxitgcilkm

tiai~xgt mcqg amccih D'I tiai~xgt diamyqi gj kxqmdkckx{ xg tiagfekpi ~mtxkaciq agexmkekef dgxb m~gqD meh I

maxkzkx{ gaaytq lmkec{ ke xbi ckzit

tiai~xgt tiagfekpiq m~g I lgti timhkc{ xbme m~gD,=>>


30/99

Ti~tiqiexmxkge gj xbiCHC tiai~xgt "21; mm+

irxtmaiccycmt hglmke kq

tiq~geqkdci jgt m~g,D,

=>>'m~g,I dkehkef

kextmaiccycmt hglmke kq

tiq~geqkdci jgt

acyqxitkef gj CHCtiai~xgtq kexg agmxih

~kx tifkge gj ~cmqlm

lildtmei


31/99


32/99

Abgciqxitgc qgytaiq# dkgq{exbiqkq

meh hiftmhmxkge hkix

gec{ jgyeh ke meklmc jmx

dkgq{exbiqkq ~tklmtkc{ q{exbiqkpih ke xbi ckzit jtgl maix{c AgM

dkgq{exbiqkq kq kebkdkxih d{ CHC y~xmoi d{ xbi ckzit

hiftmhmxkge

gec{ gaaytq ke xbi ckzit

abgciqxitgc kq agezitxih xg dkci makhq


33/99

Dkgq{exbiqkq gj abgciqxitgc


34/99


, q{exbiqkq gj lizmcgemxi

tmxi,cklkxkef qxi~

meh qxi~ qyd`iax xgkebkdkxkge d{ qxmxkeq



35/99


,q{exbiqkq gj kqg~iexie{c,~{tg~bgq~bmxi

M lgegxit~iei


36/99

Q{e

xbiqkqg

jjm

teiq{c

~{tg~

gq~b

mxi



37/99


, q{exbiqkq gj q}ymciei

m qiq}ykxit~iei

m xtkxit~iei


38/99

Q{e xb

iqkqgj

q}y

mci

ei



39/99


, q{exbiqkq gj cmegqxitgc

xbi mcc{cmlkei mexkjyefmcq

kexitjiti vkxb xbi i~grkhmxkge

qxi~ "emjxkhkei# xitjkemdkei+

l


40/99

Jgtlmxk

gegj

xbi

qxit

gctk e

fq{qxil



41/99


Xbi hilixb{cmxkge

gj cmegqxitgc kq mcqg

m yqijyc qxi~ jgt htyf

hiqkfe k%i% mpgci mexkjyefmcq

MAMX kebkdkxgtq maxbiti


42/99


43/99

Dkgq{exbiqkq qyllmt{


44/99

Dkci makhq jtgl abgciqxitgc

jgtlih jtgl abgciqxitgc ke xbi ckzit

qxgtih ke xbi fmcc dcmhhit ke dkci mq dkci

qmcxq "qghkyl meh ~gxmqqkyl+ yxkckpih hytkef hkfiqxkge gj jmxq meh gxbit

ck~kh qydqxmeaiq "max mq hixitfiexq+

tmxi cklkxkef qxi~ kq xbi agezitqkge gjabgciqxitgc xg 6,mc~bm abgciqxitgc d{ 6, ,b{htgr{cmqi


45/99

BG BG GB6m,b{htgr{cmqi

EMH^B / B / EMH^

abgciqxitgc 6m,b{htgr{abgciqxitgc

BG GB

GB

A Q

G

AgM

B

BG GB

A Q

G

AgM

Babieghigr{abgc{c, AgM

abgc{c,AgM

=4m,b{htgr{cmqiG4? EMH^B / B

/

4 AgM,QBG4

EMH^B / B/

4 AgM,QB


46/99

BG

A Q

G

A gM

B

abgc{c,AgM

B G

A

G

B

E A B4 A G G B

fc{akeiAgM,QB

Agezitqkge gj abgc{c,AgM xg

fc{agabgcka makh

fc{agabgcka makh


47/99

BG

A Q

G

AgM

B

abgc{c,AgM

BG

A

G

B

AB4 AB4 QG1B

B

xmytgabgcka makh "~tklmt{ dkci makh+

xmytkei

AgM,QB

Agezitqkge gj

abgc{c AgM xg

xmytgabgcka makh


48/99

Xmytkei

Xmytkei kq jgtlih d{ xbi hiamtdgr{cmxkge

gj a{qxika makh# vbkab ke xyte kq lmhi d{

grkhmxkge gj a{qxikei

A

AGG

BB1E

AB4

QB

A

AGG

BB1E

AB4

QG4

a{qxikei a{qxikei qycjkemxi

AB4B1E

AB4

QG1

xmytkei

/ G4 / G4 , AG4


49/99

BG GB

A Q

G

AgM

B

abieghigr{abgc{c, AgM

xmytg, meh fc{ag,abieghigr{abgcka ma"~tklmt{ dkci makhq+

BGB

AGGB

ckxbgabgcka makh "qiagehmt{ dkci makh+

hiage`yfmxkge /

6m,hib{htr{cmxkge

"amxmc{pih d{ lkatgdkmc

iep{liq+


50/99

BG

A

G

B

E AB4 AGGB

fc{agabgcka makh "~tklmt{ dkci makh+

BG

B

AGGB

hiage`yfmxkge /6,hib{htgr{cmxkge

"amxmc{pih d{ lkatgdkmc

iep{liq+

Higr{abgcka makh "qiagehmt{ dkci makh

Agezitqkge gj fc{agabgcka

makh xg higr{abgcka makh


51/99

Dkci makhq

abgcka makh kq xbi dkci makh jgyeh ke xbicmtfiqx mlgyex ke dkci

abgcka makh meh abieghigr{abgcka makh mtitijittih xg mq ~tklmt{ dkci makhq

dkci makhq mti agezitxih xg ikxbit fc{akei gtxmytkei age`yfmxiq "ke bylmeq xbi tmxkg gj

fc{akei xg xmytkei age`yfmxiq kq 10=+


52/99

M~~tgrklmxi agl~gqkxkge gj dkci qmcxq

Fc{agabgcmxi 48)

Fc{agabieghigr{abgcmxi 48)

Xmytgabgcmxi =4) Xmytgabieghigr{abgcmxi =4)

Fc{aghigr{abgcmxi, =:)

Xmytghigr{abgcmxi 2) Zmtkgyq ckxbgabgcmxi 8)


53/99

Dkci makhq

jmx hkfiqxkge ~tghyaxq mti mdqgtdih ke xbi jktqx=>> al gj qlmcc kexiqxkei

xbi ~tklmt{ meh qiagehmt{ dkci makhq mtitimdqgtdih mclgqx iracyqkzic{ ke xbi kciyltixytekef xg xbi ckzit d{ vm{ gj xbi ~gtxmcaktaycmxkge ";2 xg ;;)+

xbkq kq oegve mq xbi iexitgbi~mxka aktaycmxkge

ciqq xbme 9>> lf m hm{ iqam~iq timdqgt~xkgemeh kq iratixih ke xbi jiaiq


54/99

Dkci qmcxq

hixitfiex abmtmaxit gj dkci qmcxq kq hyi xgxbi b{htg~bgdka,b{htg~bkcka emxyti gj

xbi lgciayciq xbi ~tiqieai gj b{htgr{c "gt qycjmxi+ meh

xbi xitlkemc amtdgr{c ftgy~ ge xbi xmkcfkziq xbi lgciayci kxq b{htg~bkcka jmai

xbi qxitgkh tkef vkxb kxq ~yaoitih ~cmei~tgzkhiq xbi b{htg~bgdka jmai


55/99

Jyeaxkge gj dkci qmcxq

ilycqkjkamxkge gj jmxq hyi xg hixitfiex maxkzkx{

mkh ke xbi mdqgt~xkge gj jmx,qgcydci zkxmlkeq

"iq~iakmcc{ zkxmlke O+ maaicitmxi xbi maxkge gj ~meatimxka ck~mqi

bmzi abgcitixka maxkge qxklycmxi xbi ckzit xg

qiatixi dkci

qxklycmxi kexiqxkemc lgxkckx{

oii~ abgciqxitgc ke qgcyxkge "mq lkaicciq+


56/99

Lkrih lkaicci jgtlih d{ dkci qmcxq# xtkma{cfc{aitgcq mehj ~meatimxka

ck~mqi

DKCI MAKHQ


57/99

AB1

AB1

AB1

AGGB

B

B

B

B

ABGCMEKA MAKH

AB1

AB1

AB1

AGGB

B

B

B

B

BG GB

BG

AB1

AB1

AB1

AGGB

B

B

B

B

BG GB

AB1

AB1

AB1

AGGB

B

B

B

B

BG GB

ABGCKA MAKH

ABIEGHIGR[ABGCKA MAKH "ABIEGHKGC+YTQGHIGR[ABGCKA MAKH "YTQGHKGC+

"MAXKFMCC+"ABIEKR+

1 6

=4


58/99

FMCCQXGEI XBITM^IYXKA MFIEXQ

abieghigr{abgcka makh "abieghkgc? Abiekr+

ytqghigr{abgcka makh "ytqghkgc? Maxkfmcc+

LMG0

tihyai bi~mxka qiatixkge gj abgciqxitgc kexgdkci

kebkdkxkge gj BLFAgM tihyaxmqi0 kebkdkxabgciqxitgc dkgq{exbiqkq

keatimqi abgciqxitgc qgcydkckx{


59/99

Abieghkgc meh ytqghkgc

dgxb mti ijjiaxkzi ke hkqqgczkefabgciqxitgc qxgeiq ke qgli ~mxkiexq

ytqghkgc kq xbi 6,dixm i~klit gj abieghkgc lgqx ijjiaxkzi ke hkqqgczkef qlmcc "39

ll+ jcgmxkef qxgeiq ke m jyeaxkgekeffmccdcmhhit

ameegx hkqqgczi qxgeiq xbmx mti lgti xbme8) amcakyl d{ vikfbx


60/99

Mxbitgqacitgqkq

bmthiekef gj xbi mtxitkiq hyi xg xbi

hi~gqkxkge gj mxbitglmq

bimtx hkqimqi kq xbi cimhkef amyqi gj himxb

amyqih d{ xbi hi~gqkxkge gj abgciqxit{c

iqxitq ge xbi vmccq gj mtxitkiq

mxbitgqacitgqkq kq agtticmxih vkxb bkfbCHC meh cgv BHC


61/99


62/99

Jtihitkaoqge ,VBG acmqqkjkamxkge

X{~i KX{~i K0 keat% ab{cglkatgeq# tihyaih BHC# mdqieai gjck~g~tgxike ck~mqi? hijkakiea{ gj m~g AKK

"b{~itab{cglktgeilkm+

X{~i KK,MX{~i KK,M0 tmkqih CHC? hiatimqih amxmdgckql gj CHC

"tiai~xgt hijkakiea{ gt ~gc{fieka+X{~i KK,DX{~i KK,D0 tmkqih ZCHC / CHC? gjxie tihyaih BHC?

keatimqih ~tghyaxkge gj ZCHC / kl~mktih CHC

amxmdgckql

X{~i KKKX{~i KKK0 tmkqih KHC "h{qdixmck~g~tgxikeilkm+? mdegtlmcm~gck~g~tgxike I? kl~mktih amxmdgckql gj KHC? icizmxih

abgciqxitgc meh xtkfc{aitkhiq "jgtlitc{ oegve mq dtgmh

dixm hkqimqi+


63/99

Jtihitkaoqge ,VBG acmqqkjkamxkge

X{~i KZX{~i KZ0 tmkqih ZCHC? gjxie tihyaih BHC?

kl~mktih ZCHC amxmdgckql? hkixmt{

kehkqatixkge " jgtlitc{ oegve mq

b{~it~tidixmck~g~tgxikeilkm+

X{~i ZX{~i Z0 tmkqih ab{cglkatgeq / ZCHC? tihyaih

BHC? tihyaih ck~g~tgxike ck~mqi / ZCHCb{~itqiatixkge "jgtlitc{ oegve mq lkrih

ck~ilkm+


64/99

Jmaxgtq ~tglgxkef icizmxih dcggh

ck~khq mfi

lie 589 {imtq gj mfi? vglie 5 99 {imtq gj mfi

jmlkc{ bkqxgt{ gj AMH

qlgokef b{~itxieqkge 5=8>';> ll Bf

cgv BHC abgciqxitgc

gdiqkx{ 51>) gzitvikfbx

hkmdixiq licckxyq kemaxkzkx{' cmao gj iritakqi


65/99

Liabmekqlq gj maxkge gj htyfq

dkeh xg dkci makhq'abgciqxitgckebkdkx mdqgt~xkge'timdqgt~xkge

keatimqi ~itgrkqglmc JM grkhmxkge qxklycmxi ck~g~tgxike ck~mqi

kebkdkx xtkfc{aitkhi ck~mqi

kebkdkx BLF AgM tihyaxmqi qxklycmxiq lkatgqglmc 6,mc~bm

b{htgr{cmqi


66/99

Htyf Acmqqkjkamxkge

q{qxilka'ege,q{xilka

abgciqxitgc cgvitkef mfiexq

dkci makh qi}yiqxtmexq

qkxgqxitgcq*

~tgdyagc*

h,xb{tgrke*BLF Ag,M tihyaxmqi kebkdkxgtq

* Eg cgefit mzmkcmdci agllitakmcc{ ke xbi Y%Q


67/99


68/99

Dkci qi}yiqxitkef tiqkeq

BA

B4A

BA

B4A

ABB4A

E"AB1+1

e

ABGCIQX[TMLKEI

B4E

BE

BE

BE

"AB4+:E"AB1+1

BE

"AB4+;,AB1

GB

BE

"AB4+:E"AB

1+1

BE

"AB4+;AB1

B4E% e BAc

% e BAc

% e BAc

% e BAc % e BAc % e BAc

% e BAc% e BAc

AGCIQIZICML


69/99


AB4BE

AB4

AB4 E AB4 AB4 E

AB4 AB4

AB4

AGB AGB AGBB

AB4

AB4 E AB4

AB4

AGB

AB4

B B

AB4

E

AB4

B

E EAB4 AB4,AB4AB4 E

AB4 EB

AB4

AGB

AB4

EB AB4 AB4 B AB4,AB4,

e

AGCIQXK^GC "AGCIQXKH+


70/99

Dkci makh qi}yiqxtmexq

~g# qmjiqx# ege q{qxilka dkeh xg dkci makhq meh kebkdkx timdqgt~xkge keatimqi 6,mc~bm b{htgr{cmqi maxkzkx{ cimhkef xg

abgciqxitgc hiftmhmxkge hiatimqiq ~cmqlm CHC ~tgdcilq0

mdhglkemc hkqagljgtx# dcgmxkef# ageqxk~mxkge

hiatimqiq htyf mdqgt~xkge? vmkx 8 btq mjxitmhlkekqxtmxkge gj DMQ xg fkzi htyfq


71/99

Agciqizicml "VicAbgc+

~gc{mco{cmlkei b{htgabcgtkhi+ atgqq ckeoih

vkxb i~kabcgtgb{htke meh mco{cmxih vkxb =,

dtglghiamei meh ":,dtglgbir{c+

xtklixb{cmllgekyl dtglkhi

mzmkcmdci mq m :49 lf xmdcix

qmli liabmekql gj maxkge mq agciqxk~gc meh

abgciqx{tmlkei


72/99


htyf kexitmaxkgeq"hiatimqih qitylcizic+

mq~ktke ackehml{ake

acgjkdtmxi

jytgqilkhi

fck~pkhi

xgcdyxmlkhi

~bie{xgke

klk~tmlkei

lixb{chg~m

ekagxkeka makh

~iekakccke F

~tg~tmegcgc

xixtma{ackei

xbkmpkhi hkytixkaq

hkfgrke

b{htgagtxkqgei

~bgq~bmxi qy~~ciliexq


73/99

AB1

AB1

B1A

AB4AB1

AB1

AB1

BG

QXKFLMQXMEGC

AB1

AB1

B1A

AB4AB1

AB1

AB1

BG

DIXM QKXGQXITGC

^CMEX QXITGCQ

B1A

AB1

A

AB1


74/99

AB1

AB1

B1A

AB4AB1

AB1

BG

QXKFLMQXITGC

AB1

AB1

B1A

AB1

BG

AB1

AML^IQXTGC

AB1

AB1

B1A

AB1

AB1

BG

AB1

AB1

MC^BM=,QKXGQXITGC

Lgti ~cmex qxitgcq


75/99


76/99

BLF AgM tihyaxmqi

1 hkjjitiex tifycmxgt{ liabmekqlq mtikezgczih0

agzmciex lghkjkamxkge0 ~bgq~bgt{cmxkge d{aML^,hi~iehiex ~tgxike okemqiq kemaxkzmxi xbitihyaxmqi% Xbkq kemaxkzmxkge ame di tizitqih d{ 4q~iakjka ~bgq~bmxmqiq

hiftmhmxkge gj xbi iep{li bmcj ckji gj 1 bgytq

meh xbi bmcj,ckji hi~iehq ge abgciqxitgc cizicq fiei ir~tiqqkge0 abgciqxitgc cizicq agextgc xbi

mlgyex gj lTEM


77/99


78/99

G

AGGB

AB1

GB

QAgM

GB

AGGB

AB1

GB

B B

4 EMH^B 4 EMH^

, AgMQB

GB

AGGB

AB1

GB

B

QAgM

G

AGGB

AB1

GB

B

EMH^B EMH^B

G GBG


79/99

G

AB1

B1A

G

B1A

B

B B

G

AB1

B1A

AB1

B

AB1

E

^

G

AGGB

^b

G,

BG

Ix

J

G

G

B

BG

Ac

AcBG

Ok < =>,=>

Ok < =>,==

Ok < =>,=>

Cgzmqxmxke

BG G


80/99

AB1

BG

G

BB1A

G

LIZMQXMXKE

AB1

B

G

G

BG G

BB1A

B1A

G

CGZMQXMXKE "LIZMAGT+

AB1

BG

G

BG G

AB1B1A

G

QKLZMQXMXKE "PGAGT+

AB1

BG

AGGB

BG

BB1A

G

BG

GB

^TMZMQXMXKE "^TMZMABGC+


81/99

E

GB

AG4Em

BG

J

AB"AB1+4

JCYZMQXMXKE

E

B1AG

"B1A+4BA AB"AB1+4

J

AG4Em

GB GB

AITKZMQXMXKE

Q{exbixka qxmxkeq


82/99

BLF AgM tihyaxmqi kebkdkxgtq

^tiamyxkge0 lkch icizmxkge gj qityl mlkegxtmeqjitmqi

"qbgych di limqytih mx 4 xg 8 lgexb kexitzmcq+

lkegt keatimqiq ke atimxkei okemqi "l{g~mxb{#

lyqaci ~mke meh xiehiteiqq+

hg egx fkzi hytkef ~tifemea{


83/99

Qiciaxih b{~gck~khilka ~tghyaxq


84/99

JKDTKA MAKH HITKZMXKZIQ

AB1

B1A

G "AB4+1 A

AB1

AB1

AGGB

FILJKDTGQKC "CG^KH+

Ac G A

AB1

AB1

AGGIx

ACGJKDTMXI "MXTGLKH,Q+

Ac

GA

AB1

AB1

k^tG4A

G

JIEGJKDTMXI "XTKAGT+


85/99

Acgjkdtmxi "Mxtglkh,Q+

^tiamyxkgeq

iebmeaiq agylmtke maxkzkx{

tiemc'bi~mxka ke`yt{ agextmkehkamxkge

~tifemea{'eytqkef

abgcickxbkmqkq

lgqx agllgec{ ti~gtxih MHT mti FK ticmxih

ckzit lmckfemeakiq "egx zit{ agllge? dyx bmq cih xgqamex yqmfi+


86/99

ACGJKDTMXI

^tklmt{ maxkzkx{ ge xtkfc{aitkhiq

LGM0 keatimqiq ck~g~tgxike ck~mqi

cgvitq ZCHC

keatimqiq ~itgrkqglmc JJM grkhmxkge

kebkdkxq abgciqxitgc dkgq{exbiqkq

keatimqiq dkckmt{ qiatixkge gj abgciqxitgc

meakccmt{0 hiatimqiq ~cmxicix mhbiqkzieiqq'jkdtkegfie

Filjkdtgqkc "Cg~kh+


87/99

Filjkdtgqkc "Cg~kh+

LGM qxklycmxiq ck~g~tgxike ck~mqi kexitmax vkxb ^^MT "~itgrkqgli ~tgckjitmxgt,maxkzmxih

tiai~xgtq+

kebkdkxq xtkfc{aitkhi ck~gc{qkq ke mhk~gqi xkqqyi hiatimqiq JJM y~xmoi d{ xbi ckzit

hiatimqiq bi~mxka ZCHC'XF q{exbiqkq

qckfbx abgciqxitgc cgvitkef ijjiax

~tiamyxkgeq qklkcmt xg acgjkdtmxi l{gqkxkq "zgcyexmt{ lyqaci kejcmllmxkge+ FK "kehkfiqxkge# mdhglkemc ~mke# hkmttbim+ abgcickxbkmqkq "keatimqih abgciqxitgc dkckmt{ qiatixkge+

bmcj ckji0 =%= bgytq


88/99

Jiegjkdtmxi "Xtkagt+

m ticmxkzic{ eiv jkdtka makh hitkzmxkzi"lkatgekpih jgtl gj xbi htyf+

cgvitq ~cmqlm XF

kebkdkxq XF q{exbiqkq qxklycmxiq amxmdgckql gj ZCHC

kehkamxih ~tklmtkc{ jgt b{~itxtkfc{aitkhilkm

qmli qkhi ijjiaxq meh ~tiamyxkge mq ke gxbit

jkdtka makh agl~gyehq bmcj,ckji0 4> bgytq

Hgqi0 :6,4>= lf'hm{ vkxb limcq


89/99

Egv mcqg mzmkcmdci mq m 4>> lf xmdcix


90/99

EKAGXKEKA MAKH "Ekmake+

E

AGGB

EKAGXKEKA MAKH "EKMAKE+

M vmxit qgcydci zkxmlke gj xbi D jmlkc{?

ekagxkemlkhi kq egx maxkzi

Geai agezitxih xg xbi mlkhi# kx kq

keagt~gtmxih kexg EMH

Ke gthit xg di ijjiaxkzi# kx bmq xg di hgqih mx xbi tmxi gj =%9 xg 1%9

fl hmkc{%

M qyqxmkeih ticimqi hgqmfi jgtl kq mzmkcmdci

mhzitqi ijjiaxq0 FK hkqxytdmeaiq "itgqkge meh ycaitmxkge+

tih jcyqb iq~iakmcc{ ke xbi jmai meh eiao mtim

amyqih d{ zmqghkcmxkge gj am~kccmtkiq


91/99


92/99


93/99

Tgqyzmqxmxke "Atiqxgt+

Eiv qxmxkeq0 tgqyzmqxmxke "PH8944+

E

k^t

AGGB

B

Q

AB1

GG

GBGB

J

ekaoemlih qy~itqxmqxke' fgtkccm qxmxke diamyqi gj kxq ~gvitjyc

ijjiax ge CHC abgciqxitgc


94/99

Ipixklkdi "Pixkm+

E

GB

G

J

GB

J

IPIXKLKDI

Xbkq htyf dcgaoq xbi kexiqxkemc mdqgt~xkge gj abgciqxitgc% M hgqi gj => lf }h cimhq xg

m =;) tihyaxkge gj CHC? qbgvq timc ~tglkqi ke agldg ~tghyax vkxb qxmxkeq "Qabitkef,

^cgyfb meh Litao+


95/99

Keziqxkfmxkgemc htyfq

ma{cAgM0 abgciqxitgc ma{cxtmeqjitmqi

kebkdkxgtq

Gt~bme eyacimt tiai~xgtq0 CRT gr{abgciqxitgc tiai~xgt ,,, iebmeaih

abgciqxitgc ijjcyr

JRT dkci makh tiai~xgt ,,,, hiatimqih

abgciqxitgc agezitqkge xg dkci qmcxq


96/99

MAMX Kebkdkxgtq

Q

E

AJ1

G G

AJ1

AJ1

X>;>=1=6 ,, CRT mfgekqx

AG4B

GB

CF4:2 ,, TRT mfgekqx


97/99

MAMX Kebkdkxgtq

G

AB

AB1B1A

AB

AB1

AB1

Q

E

A

B4

A

G

B

G

AB

ABAB

B1A AB1

AB1

AB1AB1

B1A

G

MZMQILKDI "AK,=>==+


98/99

Q}ymciei q{exbmqi kebkdkxgtq

q}ymciqxke =# m jitliexmxkge ~tghyaxhitkzih jtgl ^bcglm q~iakiq"Agicgl{aixiq+

m ~gxiex kebkdkxgt gj q}ymciei q{exbmqi

~tghyaiq m lmtoih hiatimqi ke qitylabgciqxitgc meh m~gD cizicq

lm{ ti~tiqiex me mcxitemxkzi ackekamcxbitm~{ xg b{~itabgciqxitgcilkm


99/99

lipoprotein metabolism lecture for 2nd year mbbs by dr sadia haroon

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