lect 2 descending motor improved pathways

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  • 7/29/2019 Lect 2 Descending Motor IMPROVED Pathways

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    Descending motorpathways / tracts:1) PYRAMIDAL / CORTICO-SPINAL.

    2) EXTRA-PYRAMIDAL / EXTRA CORTICO-

    SPINAL. (All the descending motorpathways, other than pyramidal are calledextrapyramidal).

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    PYRAMIDAL TRACTS: Consist of 1 million fibers.

    Mostly myelinated fibers, but slow conducting.

    Tract originates from cerebral cortex.

    30% of fibers originate from primary motor area.

    Another 30% from pre-motor area & supplementary motorarea.

    40% from somatic sensory area of cerebral cortex.

    All these fibers converge through corona-radiata towardsinternal capsule.

    In internal capsule, the tract occupies the genu (the bentportion) & anterior 2/3 ofposterior limb.

    Then tract passes into midbrain, where it occupies middle 3/5of cerebral peduncle / crus cerebri.

    When tract passes through the internal capsule, fibers forcervical parts of body are in genu & fibers for lower parts ofbody are in posterior limb of internal capsule.

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    Corona radiata

    Genu ofint. capsule

    has fibers for cervical

    parts of body

    Ant. 2/3 ofpost. Limb

    ofint. cap has fib for

    Lower parts of body

    Transverse ponto-

    cerebellar fibers break thetract into small bundles

    In cerebral peduncle,

    fibers for cervical parts

    are medial

    In cerebral peduncle,

    fibers for lower parts

    are lateral

    Fibers converge through

    towards internal capsule

    PONS

    MID BRAIN

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    PONS

    MEDULLA

    PYRAMID

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    LOWER MEDULLA

    SPINAL CORD

    80% fibers cross

    MOTOR DECUSSATION

    Lat cortico-spinal tract

    Ant cortico-spinal tract

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    Alpha / gamma

    motor neuron

    3% fibers,

    no inter-neurons

    BETZ CELLS

    SPINAL CORD

    Other fibers,

    inter-neurons

    CERVICAL

    THORACIC

    LUMBAR

    45%

    20%

    35%

    SPINAL CORD

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    CORTICO SPINAL TRACTCORTICO BULBAR

    FIBERS

    BRAIN STEM

    CRANIAL NERVE NUCLEI

    CORTEX

    SPINAL CORD

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    In cerebral peduncle, fibers for cervical parts of bodyare medial & fibers for lower parts are lateral.

    From midbrain, tract enters the pons, where tract isbroken into small bundles by transverse ponto-cerebellar fibers.

    When these bundles enter medulla, these gather /unite along the anterior border of medulla to form thepyramid (a swelling). The tract is named pyramidalbecause of pyramid formation along anterior border of

    medulla. In lower part of medulla, 80% of fibers cross over to

    opposite side, to form MOTOR DECUSSATION.(Sensory decussation: fibers from nucleus gracilus &cuneatus).

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    Fig 55-4, Guyton

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    After motor decussation, crossed fibers enter lateralwhite columns of spinal cord to form lateral cortico-spinal tract.

    Fibers of tract which remain uncrossed, enter anteriorwhite column of spinal cord to form anterior cortico-spinal tract.

    Fibers ofanterior cortico-spinal tract terminate inventral horn of cervical & upper thoracic segments ofspinal cord. These fibers terminate onto motor neurons

    ( aplha & gamma). It is thought that these fibers arefrom supplementary motor area, for control ofattitudinal or positional movements,e-g, in climbingposture.

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    Fig 55-4, Guyton

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    Fibers oflateral cortico-spinal tract

    terminate onto the motor neurons in

    ventral horn of spinal cord at variouslevels.

    From cortico-spinal tract as a whole, 45%

    fibers terminate in cervical segments,35% in lumbar& 20% in thoracic

    segments of spinal cord.

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    Most of cortico-spinal fibers for their

    termination first synapse with inter-

    neurons which in turn synapse with motorneurons (alpha & gamma).

    Only fibers which arise from Betz cells

    (Giant pyramidal cells), which form only3% fibers, terminate directly into motor

    neurons.

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    Certain branches of cortico-spinal tract go todifferent brain parts:

    To caudate & lentiform nuclei.

    To red nucleus. To olivary nuclei & reticular formation.

    There are also cortico-bulbar fibers whichcome along cortico-spinal tract. In the brain

    stem these fibers cross over to opposite side toterminate with motor neurons in nuclei ofcranial nerves.

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    Fig 55-5, Guyton

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