lect 1 descending motor improved pathways

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    Descending motorpathways / tracts:1) PYRAMIDAL / CORTICO-SPINAL.

    2) EXTRA-PYRAMIDAL / EXTRA CORTICO-

    SPINAL. (All the descending motorpathways, other than pyramidal are calledextrapyramidal).

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    PYRAMIDAL TRACTS: Consist of 1 million fibers.

    Mostly myelinated fibers, but slow conducting.

    Tract originates from cerebral cortex.

    30% of fibers originate from primary motor area.

    Another 30% from pre-motor area & supplementarymotor area.

    40% from somatic sensory area of cerebral cortex.

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    All these fibers converge through corona-radiata

    towards internal capsule.

    In internal capsule, the tract occupies the genu (thebent portion) & anterior 2/3 ofposterior limb.

    Then tract passes into midbrain, where it occupiesmiddle 3/5 of cerebral peduncle / crus cerebri.

    When tract passes through the internal capsule, fibersfor cervical parts of body are in genu & fibers for lowerparts of body are in posterior limb of internal capsule.

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    Corona radiata

    Genu ofint. capsule

    has fibers for cervical

    parts of body

    Ant. 2/3 ofpost. Limb

    ofint. cap has fib for

    Lower parts of body

    Transverse ponto-

    cerebellar fibers break thetract into small bundles

    In cerebral peduncle,

    fibers for cervical parts

    are medial

    In cerebral peduncle,

    fibers for lower parts

    are lateral

    Fibers converge through

    towards internal capsule

    PONS

    MID BRAIN

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    In cerebral peduncle, fibers for cervical parts of bodyare medial & fibers for lower parts are lateral.

    From midbrain, tract enters the pons, where tract isbroken into small bundles by transverse ponto-cerebellar fibers.

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    When these bundles enter medulla,

    these gather / unite along the anteriorborder of medulla to form the pyramid (aswelling).

    The tract is named pyramidal because ofpyramid formation along anterior borderof medulla.

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    PONS

    MEDULLA

    PYRAMID

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    In lower part of medulla, 80% of fibers

    cross over to opposite side, to form

    MOTOR DECUSSATION.

    (Sensory decussation: fibers from

    nucleus gracilus & cuneatus).

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    LOWER MEDULLA

    SPINAL CORD

    80% fibers cross

    MOTOR DECUSSATION

    Lat cortico-spinal tract

    Ant cortico-spinal tract

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    Fig 55-4, Guyton

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    After motor decussation, crossed fibers enter lateralwhite columns of spinal cord to form lateral cortico-spinal tract.

    Fibers of tract which remain uncrossed, enter anteriorwhite column of spinal cord to form anterior cortico-spinal tract.

    Fibers ofanterior cortico-spinal tract terminate inventral horn of cervical & upper thoracic segments ofspinal cord.

    These fibers terminate onto motor neurons ( aplha &

    gamma).

    It is thought that these fibers are from supplementarymotor area, for control of attitudinal or positionalmovements,e-g, in climbing posture.

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    Fig 55-4, Guyton

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    Fibers oflateral cortico-spinal tract

    terminate onto the motor neurons in

    ventral horn of spinal cord at variouslevels.

    From cortico-spinal tract as a whole,

    45% fibers terminate in cervicalsegments,

    35% in lumbar

    20% in thoracic segments of spinalcord.

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    Alpha / gamma

    motor neuron

    3% fibers,

    no inter-neurons

    BETZ CELLS

    SPINAL CORD

    Other fibers,

    inter-neurons

    CERVICAL

    THORACIC

    LUMBAR

    45%

    20%

    35%

    SPINAL CORD

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    Most of cortico-spinal fibers for their

    termination first synapse with inter-neurons which in turn synapse with motor

    neurons (alpha & gamma).

    Only fibers which arise from Betz cells

    (Giant pyramidal cells), which form only

    3% fibers, terminate directly into motor

    neurons.

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    CORTICO SPINAL TRACTCORTICO BULBAR

    FIBERS

    BRAIN STEM

    CRANIAL NERVE NUCLEI

    CORTEX

    SPINAL CORD

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    Certain branches of cortico-spinal tract go todifferent brain parts:

    To caudate & lentiform nuclei.

    To red nucleus.

    To olivary nuclei & reticular formation.

    There are also cortico-bulbar fibers whichcome along cortico-spinal tract. In the brainstem these fibers cross over to opposite side toterminate with motor neurons in nuclei ofcranial nerves.

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