FOLIC ACIDFolate

FOLIC ACID

Folic acid is a water-soluble vitamin B9. It is also known as vitamin B9, vitamin

Bc or folacin and folate (the naturally occurring form)

SOURCES OF FOLIC ACID Folate is found naturally in some foods,

including leafy vegetables, citrus fruits, beans (legumes), liver and whole grains

Folic Acid is found in various products as a food supplement.

"Folic acid" is the term used for the man-made or synthetic form of the vitamin.

DAILY REQUIREMENTS

RDI= Refrence Daily Intake, UL=tolerable upper intake levels

BIOLOGICAL ROLES Folic Acid is essential to

numerous bodily functions. The human body needs folate to

synthesize DNA and repair DNA, as well as to act as a cofactor in biological reactions involving folate.

FOLIC ACID Folic Acid is especially important in

aiding rapid cell division and growth, such as in infancy and pregnancy.

Children and adults both require folic acid to produce healthy red blood cells and prevent anemia. Since folate deficiency limits cell division, erythropoiesis is hindered and leads to megaloblastic anemia

FOLIC ACID

FOLIC ACID DEFICIENCY

A lack (deficiency) of folate in the human body can be caused by certain diseases, by taking certain medications, or by not getting enough folate in your diet

FOLIC ACID DEFICIENCY Deficiency can result in many health

problems, the most notable one being neural tube defects in developing embryos which includes NTDs( Neural Tube Defects) i.e. Anencephaly Spina Bifida

FOLIC ACID DEFICIENCYCommon symptoms of folate deficiency include: diarrhea, macrocytic anemia with weakness or shortness of breath, nerve damage with weakness and limb numbness (peripheral

neuropathy), pregnancy complications such as NTDs, recurrent

pregnancy loss, low birth weight mental confusion, forgetfulness or other cognitive declines, mental depression, sore or swollen tongue, peptic or mouth ulcers, headaches, heart palpitations, Irritability, and behavioral disorders

Anencephaly is the absence of a large part of

the brain and the skull

Anencephaly is a neural tube defect that occurs when the cephalic (head) end of the neural tube fails to close, usually between the 23rd and 26th day of pregnancy, resulting in the absence of a major portion of the brain, skull, and scalp

ANENCEPHALY

ANENCEPHALY Infants born with anencephaly are

usually blind, deaf, unconscious, and unable to feel pain

There is no cure or standard treatment for anencephaly

Most anencephalic babies do not survive birth. If the infant is not stillborn, then he or she will usually die within a few hours or days after birth.

ANENCEPHALY

SPINA BIFIDA Spina bifida literally means ‘split

spine’ A fault in the development of the spinal

cord and surrounding bones (vertebrae) leaves a gap or split in the spine. The spinal cord has not formed properly, and may also be damaged. 

SPINA BIFIDA

SPINA BIFIDA Spina bifida is a developmental

disorder caused by the incomplete closing of the embryonic neural tube

Complications of spina bifida can range from minor physical problems to severe physical and mental disabilities

It can lead to varying degree of loss of muscle function and sensation

Surgery has made it possible to treat mild cases by closure of the defect and orthopedic procedures can be applied to balance muscle power

SPINA BIFIDA PREVENTION At present causation is unknown and

research continues. However, we do know that taking folic acid supplements can reduce the risk of spina bifida in unborn babies.

For families with no history of spina bifida it is recmomended that women take an ‘over the counter’ dose of 400mcg daily.

For families where there is a history of spina bifida, a prescription dose (5mg) of folic acid is needed

THE PRODUCT

Contains contains L-Methylfolate 400mcg

L-Methylfolate is the biologically active form of folic acid

L-Methylfolate is the natural, active form of folic acid used at the cellular level

It bypasses several metabolic steps in the body as it is already present in the absorbable form

is an orally administered prescription medical food for the management of low folate levels

Folic Acid

Dihydrofolate(Dietary Folate)

Tetrahydrofolate

5,10 Methylene THF

DHF Reductase Enzyme

L METHYLFOLAT

E

L METHYLFOLAT

E

MTHFR

MTHFR= Methylene-tetra-hydrofolate

DHF = Di-hydrofolate

ADVANTAGES OF L-METHYLFOLATE

L-methylfolate is a Novel form of Folate More effective than folic acid L-methylfolate is a high absorbable form of folic acid L-methylfolate is the bioactive form of folic acid

ready to use at cellular level. Unlike regular folic acid, L-methylfolate does not

require enzymatic conversion to L-methylfolate in the body

L-methylfolate is 7 times more bioavailable than folic acid

L-methylfolate is less likely to mask a vitamin B deficiency compared to folic acid

L-methylfolate increases RBC folate better than folic acid

PRESENTATION Hifol Tablets 2×15’s Price is Rs.200.00/pack

DETAILING STORY Hifol Detailing Story