• Introduction to the three research groups- What we do- What methods we use- General research topics- Possible Bakk-Arbeit Projects

• What you should expect from us

• What we expect from you

KFU – Analytische Chemie

Analytical Chemistry for Health and EnvironmentWalter Gössler, Christoph Kurta

Three Research Groups

Elektroanalysis and SensorsKurt Kalcher, Herbert Greschonig

Trace Element MetabolomicsKevin Francesconi, Doris Kuehnelt, Georg Raber, Florian Geyer

Analytical Chemistry for Health and Environment (ACHE)

Dr Walter Gösslerhttp://www.uni-graz.at/achwww/achwww_research/achwww_ache.htm

walter.goessler@uni-graz.at3805302

• Read the ACHE homepage for projects

• Provides information for students during his courses

• Pleased to talk to students about projects at any time

Electroanalytik und Sensorik (EAS)

Dr Kurt Kalcherhttp://www.uni-graz.at/achwww/achwww_research/achwww_eas.htm

Kurt.kalcher@uni-graz.at3805310

Themen• Elektroanalytik• Automatisierung und Datenmanagement• Schul-orientierte Themen

Electroanalytik und Sensorik: Themen

Elektroanalytik• elektrochemische Sensoren und Biosensoren

– Kohlepasteelektroden– Screen Printed Elektroden– Inkjet-gedruckte Elektroden– Mediatoren (Metalloxide)– „Nanosized materials“ für Sensoren

» Nanopartikel» Carbon Nanotubes

• Schwerpunkte– Enzym-Biosensoren

» Aminoxidasen und andere Oxidasen– Sensoren für Totale Antioxidative Kapazität

Electroanalytik und Sensorik: Themen

Automatisierung und Datenmanagement

• Mikroprozessor-gesteuerte Anwendungen– Programmierung von Mikroprozessoren

– Anbindung von Mikroprozessoren an Personal Computers

– Datenaufnahme und -handling

– Windows-Programme mit Visual Basic

Schul-orientierte Themen– für Lehramtskandidaten

– mit besonderen Bezugspunkten für Unterrichtsgestaltung

Trace Element Metabolomics

• Chemical processes in biological systems

• Investigating metabolic profiles of organisms

• Environmental & nutritional metabolomics

• Our main techniques are HPLC/MS and GC/MS.

http://www.uni-graz.at/achwww/achwww_research/achwww_tem.htm

kevin.francesconi@uni-graz.at

Some current projects

• Heart disease & arsenic exposure (Johns Hopkins University & ACHE)

• Arsenic in food: toxicity & metabolism (Uni Münster)

• Are small selenium species anti-cancer agents? (Roswell Park Cancer Clinic)

• Is arsenic essential? (Woods Hole Oceanographic Institute & Uni Canberra)

• Trace elements in oil (Chevron Energy Technology, Texas)

Bestimmung von Selenverbindungen in

• Nahrungsmitteln • Urin• Blut

Selenmetabolismus/Selenspeziesanalytik

• Selen und Selenverbindungen in Nahrungsmitteln und Nahrungsergänzungsmitteln

• Menschlicher Selenmetabolismus• Biomarker für den Selenstatus?

• Probenvorbereitung (Extraktion)

• Bestimmung der Selenspezies

doris.kuehnelt@uni-graz.at

Arsenic instead of phosphorus?

• Arsenic lipids are natural compounds in algae

• Are arsenolipids used in place of phospholipids?

• Oceanography & speciation

As

CH3

CH3

O OH

O

georg.raber@uni-graz.at

What you should expect from us

• Instruction in an analytical process

• Supervision in planning and carrying out experiments as part of a small project

• Advice on the analysis of data

• Guidance on the preparation of the written report (in English if you wish. Why English?)

What we expect from you

• Background reading on the topic

• Plan your experiments (maximise your time)

• Interact with the research group

• An early outline of what you will write

• A concise report of your project (20 pages)- why?- how?- what?

Blaise Pascal: 1623-1662

French mathematician and philosopher

• The heart has its reasons which the mind knows nothing of

• I would have written a shorter letter, but I did not have the time