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Draft Agenda

JRC Summer School on Alternative Approaches for Risk

Assessment

16. – 19. May 2017

Day 1 Tuesday, 16th May

(building 58c/Auditorium)

12:00–13:30 Registration and Welcome lunch 13:30–13:50 Welcome and presentation of directorate F and unit F3 activity Elke Anklam

SESSION 1: Risk Assessment - Perspectives across Regulations 1 13:50-14:10 Risk assessment overview Annika Hanberg 14.10-14:30 International acceptance of alternative methods and

approaches Valerie Zuang 14.30-14:50 Industrial perspective Catherine Mahony 14:50-15:10 Regulatory perspective ECHA (chemicals)

George Fotakis (tbc) 15:10–15:40 Coffee Break

SESSION 2: Risk Assessment - Perspectives across Regulations 2 15:40-16:10 Regulatory perspective EFSA (food and pesticides)

Andrea Terron 16:10-16:30 Regulatory perspective EMA (medicinal products)

Jean-Marc Vidal 16:30-17:30 Plenary discussion

all speakers

17:30-20:00 Aperitivo (building 101) 20:00 Bus departure to hotels

Day 2 Wednesday, 17th May

(building 58c/Auditorium)

SESSION 3: Hazard identification and in vitro models for organ toxicities

09:00-09:20 Hazard identification

Federica Madia 09:20-09:35 In vitro models for organ toxicities – brain

Francesca Pistolatto 09:35-09:50 In vitro models for organ toxicities – liver

Ian Cotgreave 09:50-10:05 In vitro models for organ toxicities – heart

Jochem Louisse 10:05-10:20 In vitro models for organ toxicities – lung Lena Palmberg 10:20-10:35 In vitro models for organ toxicities – kidney

Anja Wilmes 10:35–11:00 Coffee Break

SESSION 4: Current Concepts and New Approaches

11:00-11:20 In silico, computational models David Asturiol

11:20-11:40 Exposure assessment, Aggregate Exposure Pathway (AEP) Alicia Paini

11:40-12:00 ADME, toxicokinetics Alfonso Lostia

12:00-12:20 Adverse Outcome Pathways (AOPs) Brigitte Landesmann

12:20-12:40 Integrated Approaches to Testing and Assessment (IATA) Silvia Casati

12:40–14:00 Lunch break

THE PATH FROM SCIENCE TO PROTECTION OF HUMAN HEALTH AND THE ENVIRONMENT

THE PATH FROM SCIENCE TO PROTECTION OF HUMAN HEALTH AND THE ENVIRONMENT

Day 2 Wednesday, 17th May

14:00 – 15:30 POSTER SESSION I 14:00-14:30 10 flash poster presentations 15:30–16:00 Coffee Break

16:00 – 17:30 POSTER SESSION II

16:00-16:30 10 flash poster presentations 20:00 Bus departure to hotels

Day 3 Thursday, 18th May (building 58c/Auditorium and building 101)

SESSION 5 Validation of Alternative Methods

09:00-09:20 3Rs and environmental toxicity Marlies Halder 09:20-09:40 Principles of good in vitro method practice

Sandra Coecke

09:40-10:00 Validation process Joao Barroso

10:00-10:20 Uncertainty analysis Andrea Richarz

10:20-10:50 Coffee Break

SESSION 6: Hot Topics 10:50-11:10 Mixtures Sander Van Der Linden 11:10-11:30 Endocrine disruptors Elise Grignard 11:30-11:50 Virtual Physiological Human (VPH) Liesbet Geris 11:50-12:10 Is children's health protected by current regulations? Example of DNT Anna Price 12:10-12:30 Nanomaterials – differences to chemicals in Risk Assessment

Juan Riego Sintes

12:30-13:45 Lunch break

SESSION 7 Tools and DBs; Visit to laboratories

13:44 -14:00 Overview of afternoon activities Brigitte Landesmann 14:00-16:00 Marketplace: various databases: AOP KB, DB ALM, IPCheM, Cosmos

DB and KNIME, QSAR Toolbox, Genotox & Carcinogenicity DB; visit of laboratories and the "Cage" Coffee

SESSION 8: World café

16:00-17:30 World Café 17:30-18:00 table hosts report back to the plenary 18:00-18:30 AOP game 19:00 Departure for Social Dinner at La Quassa

Day 4 Friday, 19th May (Visitors Centre;)

SESSION 9: life-cycle assessment and virtual tours

09:00 -10:30

09:15 – 09:45 Life-cycle Assessment (LCA) (2x) 10:00 – 10:30 Erwan Saouter In parallel Virtual Tours 10:30 – 11:00 Coffee Break

SESSION 10: 11:00 - 12:30

• Quiz

• Marketplace: Career opportunities:, Collaborative Doctoral Partnerships (CDP)

• Poster price award and concluding remarks Elisabet Berggren

12:30 – 14:00 Farewell Lunch 14:00 Bus departure to airport/ train station/ hotels

THE PATH FROM SCIENCE TO PROTECTION OF HUMAN HEALTH AND THE ENVIRONMENT