【jama oncol. 3(2017)49-55】association … colitis with concomitant use of nsaids and proton pump...

NO 一般名文献名

1 ラベプラゾールナトリウム【Aliment Pharmacol Ther. 43(2016)1004-1013】High risk of drug-inducedmicroscopic colitis with concomitant use of NSAIDs and proton pump inhibitors

2 ジクロフェナクナトリウム【Dis Colon Rectum. 59(2016)1087-1097】Postoperative nonsteroidal anti-inflammatory drug use and intestinal anastomotic dehiscence: A systematic reviewand meta-analysis

3 ピタバスタチンカルシウム【Ther Clin Risk Manag. 12(2016)1533-1543】Impact of statins on risk of new onsetdiabetes mellitus: a population-based cohort study using the Korean National HealthInsurance claims database

4 乾燥スルホ化人免疫グロブリン【Vox Sang. 110(2016)27-35】Acute pulmonary embolism caused by highly aggregatedintravenous immunoglobulin

5 フェノバルビタールナトリウム【Indian J Pediatr. 82(2015)225-259】Bone mineral density in ambulatory children withepilepsy

6 エソメプラゾールマグネシウム水和物【Circulation. 134(2016)】Proton Pump Inhibitor Use Increases the Associated Risk ofFirst-Time Ischemic Stroke. A Nationwide Cohort Study

7 オメプラゾール【Circulation. 134(2016)】Proton Pump Inhibitor Use Increases the Associated Risk ofFirst-Time Ischemic Stroke. A Nationwide Cohort Study

8クロルフェニラミンマレイン酸塩含有一般用医薬品

【第69回日本酸化ストレス学会学術集会. (2016)】O－36胆管癌における酸化ストレスの病態への関与と抗酸化治療の可能性についての検討

9 アロプリノール【Allergy. 71(2016)205-206】HLA-B*58:01 and allopurinol high dose were associatedwith allopurinol induced cutaneous adverse drug reactions in Thai population

10タゾバクタムナトリウム・ピペラシリンナトリウム

【J Toxicol Sci. 41(2016)143-143】. ペニシリンベース抗生物質のアモキシシリン,アンピシリン,およびピペラシリンがヒト肝チトクロームP450の薬物代謝活性に及ぼす影響

11レジパスビル　アセトン付加物・ソホスブビル

【Am J Gastroenterol. 111(2016)398-399】Recurrence of Hepatocellular CarcinomaFollowing Eradication of Hepatitis C Infection

12 ソホスブビル【Am J Gastroenterol. 111(2016)398-399】Recurrence of Hepatocellular CarcinomaFollowing Eradication of Hepatitis C Infection

13 アセトアミノフェン【JAMA Pediatr. 170(2016)964-970】Association of Acetaminophen use duringpregnancy with behavioral problems in childhood: evidence against confounding

14 塩酸シプロフロキサシン【Clin Infect Dis. 15(2016)1251-1258】Shiga toxin-producing Escherichia coliinfection, antibiotics, and risk of developing hemolytic uremic syndrome: A meta-analysis

15 リュープロレリン酢酸塩【JAMA Oncol. 3(2017)49-55】Association Between Androgen Deprivation Therapyand Risk of Dementia

研究報告の報告状況（平成28年12月1日～平成29年3月31日）

資料2-4

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16 リュープロレリン酢酸塩【JAMA Oncol. 3(2017)49-55】Association Between Androgen Deprivation Therapyand Risk of Dementia

17ノルエチステロン・エチニルエストラジオール

【BJOG. 122(2015)1349-1361】Hormonal contraceptive use before and afterconception in relation to preterm birth and small for gestational age: an observationalcohort study

18 アセトアミノフェン含有一般用医薬品【J Am Geriatr Soc. 64(2016)e90-e93】Advanced age and female sex as risk factorsfor high anion gap metabolic acidosis after a drug interaction between paracetamoland flucloxacillin: a case series

19 ジクロフェナクナトリウム【J Gastrointest Surg. 20(2016)776-782】Risk of anastomotic leakage withnonsteroidal anti-inflammatory drugs within an enhanced recovery program

20 フルボキサミンマレイン酸塩【第22回日本薬剤疫学会学術総会. (2016)96-97】レセプトデータを用いた妊娠中の精神疾患とその治療薬が出生児に与える影響の解析

21 フルボキサミンマレイン酸塩【第22回日本薬剤疫学会学術総会. (2016)96-97】レセプトデータを用いた妊娠中の精神疾患とその治療薬が出生児に与える影響の解析

22 アスピリン・ランソプラゾール配合剤【ProgCardiovasc Dis. 58(2016)495-504】Which Aspirin Dose and Preparation Is Bestfor the Long-Term Prevention of Cardiovascular Disease and Cancer? EvidenceFrom a Systematic Review and Network Meta-Analysis

23 エスシタロプラムシュウ酸塩【J Mol Cell Cardiol. 98(2016)28-36】Early citalopram treatment increases mortalitydue to left ventricular rupture in mice after myocardial infarction

24フルチカゾンプロピオン酸エステル・ホルモテロールフマル酸塩水和物

【Respir Med. 120(2016)54-63】Incidence of oral thrush in patients with COPDprescribed inhaled corticosteroids: Effect of drug, dose, and device

25 ジクロフェナクナトリウム【Dis Colon Rectum. 59(2016)1087-1097】Postoperative nonsteroidal anti-inflammatory drug use and intestinal anastomotic dehiscence: A systematic reviewand meta-analysis

26 非ピリン系感冒剤（４）【JAMA Pediatr. 170(2016)964-970】Association of acetaminophen use duringpregnancy with behavioral problems in childhood: evidence against confounding

27 レボフロキサシン水和物【Gynecol Oncol. 143(2016)204】Antibiotic use negatively influences survival inepithelial ovarian cancer: A case for studying the microbiome

28 アトルバスタチンカルシウム水和物【Medicine. 95(2016)1-7】Risks of adverse events following coprescription of statinsand calcium channel blockers：a nationwide population-based study

29 パリペリドン【東邦医学会雑誌. 63(2016)233-234】非定型抗精神病薬paliperidoneの電気薬理学的作用－ハロセン麻酔犬での評価

30 フルボキサミンマレイン酸塩【J Intern Med. 280(2016)407-418】Preadmission use of selective serotonin reuptakeinhibitors and short-term mortality in diabetic patients hospitalized due to stroke

31 アセトアミノフェン【Pharmacoepidemiol Drug Saf. 25(2016)188-195】Association of prenatal exposureto acetaminophen and coffee with childhood asthma

32 フェノバルビタールナトリウム【CNS Drugs. 30(2016)1201-1207】Phenobarbital Versus Valproate for GeneralizedConvulsive Status Epilepticus in Adults: A Prospective Randomized Controlled Trialin China

2

33 メチルエルゴメトリンマレイン酸塩【日赤医学. 68(2016)212】分娩第3期オキシトシン投与患者の分娩時出血量に関連する因子の検討

34 乾燥弱毒生麻しん風しん混合ワクチン【Pediatr Infect Dis J. 35(2016)1232-1241】Randomized Trials Comparing InactivatedVaccine After Medium- or High-titer Measles Vaccine With Standard Titer MeaslesVaccine After Inactivated Vaccine: A Meta-analysis

35 ランソプラゾール【Circulation. 134(2016)】Proton Pump Inhibitor Use Increases the Associated Risk ofFirst-Time Ischemic Stroke. A Nationwide Cohort Study

36 インスリン　アスパルト（遺伝子組換え）【第58回日本消化器学会大会. (2016)】インスリン投与は大腸ACFの発生を促進し、大腸発癌リスクを増大する

37 インスリン　アスパルト（遺伝子組換え）【Lancet Diabetes Endocrinol. (2016)1-10】Association of insulin dosage withmortality or major adverse cardiovascular events：a retrospective cohort study

38 インスリン　アスパルト（遺伝子組換え）【Eur Heart J. 5(2016)455-462】Heart failure in patients with diabetes undergoingprimary percutaneous coronary intervention

39 ワルファリンカリウム【Ann Pharmacother. 50(2016)909-917】Evaluation of a Potential Interaction BetweenNew Regimens to Treat Hepatitis C and Warfarin

40 ロペラミド塩酸塩【MMWR Morb Mortal Wkly Rep. 65(2016)1276-1277】Notes from the Field: CardiacDysrhythmias After Loperamide Abuse -- New York, 2008-2016

41 モルヒネ塩酸塩水和物【Br J Clin Pharmacol. 82(2016)1343-1350】 Abciximab as a bridging strategy toovercome morphine-prasugrel interaction in STEMI patients

42 パロキセチン塩酸塩水和物【BJOG. 123(2016)1929-1936】Antidepressant use in late gestation and risk ofpostpartum haemorrhage: a retrospective cohort study

43 パロキセチン塩酸塩水和物【J Clin Psychiatry. 77(2016)e1124-e1129】Selective serotonin reuptake inhibitorsdecrease pancreatic insulin secretion in older adults and increase the risk of insulindependence in type 2 diabetes patients

44 ラベプラゾールナトリウム【Exp Clin Transplant. 14(2016)503-510】Effect of the Prophylactic Use of Proton-Pump Inhibitors on the Pattern of Gastrointestinal Symptoms in Patients Late AfterKidney Transplant

45 ラベプラゾールナトリウム【Clin Gastroenterol Hepatol. 14(2016)1706-1719】Use of Proton Pump Inhibitors andRisks of Fundic Gland Polyps and Gastric Cancer: Systematic Review and Meta-analysis

46 エストラジオール吉草酸エステル【J Clin Endocrinol Metab. 100(2015)4012-4020】Oral vs Transdermal EstrogenTherapy and Vascular Events: A Systematic Review and Meta-Analysis


【J Clin Endocrinol Metab. 100(2015)4012-4020】Oral vs Transdermal EstrogenTherapy and Vascular Events: A Systematic Review and Meta-Analysis

48 プレドニゾロン【J Gastroenterol. 51(2016)999-1010】Nationwide prospective and retrospectivesurveys for hepatitis B virus reactivation during immunosuppressive therapies

49 ジクロフェナクナトリウム【医療薬学. 42(2016)717-726】国内自発報告データベースを用いたデフェラシロクスと他剤の併用による急性腎不全リスクのシグナル検出とケースコントロール研究による評価

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50 インフリキシマブ（遺伝子組換え）【J Eur Acad Dermatol Venereol. 30(2016)1942-1950】Survival of classic andbiological systemic drugs in psoriasis: results of the BIOBADADERM registry andcritical analysis

51 抑肝散【第37回日本臨床薬理学会学術総会. (2016)】低アルブミン血症は抑肝散製剤による低カリウム血症のリスク因子である

52メチルプレドニゾロンコハク酸エステルナトリウム

【第86回日本感染症学会西日本地方会学術集会，第59回日本感染症学会中日本地方会学術集会，第64回日本化学療法学会西日本支部総会. (2016)】マイコプラズマ肺炎に対する高用量メチルプレドニゾロン（ステロイドパルス）併用の効果

53 ザナミビル水和物【医薬品情報学. 18(2016)38-45】有害事象自発報告データベース（JADER）によるインフルエンザ治療薬と精神神経症状の関連についての検討

54 デフェラシロクス【医療薬学. 42(2016)717-726】国内自発報告データベースを用いたデフェラシロクスと他剤の併用による急性腎不全リスクのシグナル検出とケースコントロール研究による評価

55 ボリコナゾール【Clin Infect Dis. 58(2014)997-1002】Voriconazole-Associated Cutaneous Malignancy:A Literature Review on Photocarcinogenesis in Organ Transplant Recipients

56 クロピドグレル硫酸塩【Eur Neurol. 76(2016)161-166】Potentially serious drug-drug interactions in olderpatients hospitalized for acute ischemic and hemorrhagic stroke

57 オメプラゾール【Eur Heart J. 37(2016)1205-1206】Dose-response relationship between proton pumpinhibitor use and associated risk of myocardial infarction: a nationwide cohort study

58 アロプリノール【J Invest Dermatol. 136(2016)1373-1381】Impact of the HLA-B*58:01 Allele andRenal Impairment on Allopurinol-Induced Cutaneous Adverse Reactions

59 エスシタロプラムシュウ酸塩【J R Soc Med. 109(2016)381-392】Precursors to suicidality and violence onantidepressants: systematic review of trials in adult healthy volunteers

60リルピビリン塩酸塩・エムトリシタビン・テノホビル　ジソプロキシルフマル酸塩

【PLOS One. 11(2016)e0162320】Risk of Chronic Kidney Disease among PatientsDeveloping Mild Renal Impairment during Tenofovir-Containing AntiretroviralTreatment

61 エスフルルビプロフェン・ハッカ油【Int J Clin Pharmacol Ther. 54(2016)782-794】Prediction of fetal ductus arteriosusconstriction by systemic and local dermatological formulations of NSAIDs based onPK/PD analysis

62 リスペリドン【Alzheimer's and Dementia. 12(2016)823-830】Mortality risk in current and newantipsychotic Alzheimer's disease users: Large scale Japanese study

63 フェニトイン【Brain and Behavior. 6(2016)e00554】Association between antiepileptic drugs andhepatocellular carcinoma in patients with epilepsy: a population-based case-controlstudy

64 フェニトイン・フェノバルビタール【Brain and Behavior. 6(2016)e00554】Association between antiepileptic drugs andhepatocellular carcinoma in patients with epilepsy: a population-based case-controlstudy

65 ハロペリドールデカン酸エステル【Alzheimer's and Dementia. 12(2016)823-830】Mortality risk in current and newantipsychotic Alzheimer's disease users: Large scale Japanese study

66 アロプリノール【J Invest Dermatol. 136(2016)1373-1381】Impact of the HLA-B*58:01 Allele andRenal Impairment on Allopurinol-Induced Cutaneous Adverse Reactions

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67 パクリタキセル（アルブミン懸濁型）【Biomedical Reports. 5(2016)141-145】Potential drug interaction between paclitaxeland clopidogrel

68 アドレナリン【Heart Surg Forum. 18(2015)E6-E10】Renal Failure after Coronary Bypass Surgeryand the Associated Risk Factors

69 ソホスブビル【Hepatology. 64(2016)447A】Does successful viral eradication translate intobeneficial long-term clinical outcome of patients with advanced liver disease due tohepatitis C after DAA therapy?


【Hepatology. 64(2016)447A】Does successful viral eradication translate intobeneficial long-term clinical outcome of patients with advanced liver disease due tohepatitis C after DAA therapy?

71 塩酸セルトラリン【Basic Clin Pharmacol Toxicol. 119(2016)38-39】Differential effects of SSRI andother antidepressant drugs on the risk of hip fracture: a case control study　股関節部骨折リスクに対するSSRIと他の抗うつ薬の異なる影響：症例対照研究

72 ゲムシタビン塩酸塩【Radiother Oncol. 118(2016)424-429】Risk factors for vertebral compressionfractures in preoperative chemoradiotherapy with gemcitabine for pancreatic cancer

73 オメプラゾール【Eur Heart J. 37(2016)1205-1206】Dose-response relationship between proton pumpinhibitor use and associated risk of myocardial infarction: a nationwide cohort study

74 エソメプラゾールマグネシウム水和物【Eur Heart J. 37(2016)1205-1206】Dose-response relationship between proton pumpinhibitor use and associated risk of myocardial infarction: a nationwide cohort study

75 ドルテグラビルナトリウム【HIV Med. 18(2017)56-63】Higher rates of neuropsychiatric adverse events leadingto dolutegravir discontinuation in women and older patients

76 チカグレロル【Eur Heart J. 37(2016)1158】Comparison of the new oral P2Y12 inhibitor(prasugrel/ticagrelor) to clopidogrel in type 2 diabetes mellitus patients with AMI.

77 パロキセチン塩酸塩水和物【BJOG. 123(2016)1900-1907】Selective serotonin reuptake inhibitor (SSRI) useduring pregnancy and risk of preterm birth: a systematic review and meta-analysis

78 オランザピン【J Am Geriatr Soc. 64(2016)1203-1209】Antipsychotic drugs and risk of hip fracturein people aged 60 and older in Norway

79 ハロペリドールデカン酸エステル【JAMA Internal Medicine. (2016)E1-E9】Efficacy of Oral Risperidone, Haloperidol, orPlacebo for Symptoms of Delirium Among Patients in Palliative Care

80 リスペリドン【JAMA Internal Medicine. (2016)E1-E9】Efficacy of Oral Risperidone, Haloperidol, orPlacebo for Symptoms of Delirium Among Patients in Palliative Care

81 ハロペリドールデカン酸エステル【Alzheimer's and Dementia. 12(2016)823-830】Mortality risk in current and newantipsychotic Alzheimer's disease users: Large scale Japanese study

82 ドキソルビシン塩酸塩【Oncology. 91(2016)274-282】Incidence and predictors of febrile neutropenia amongearly-stage breast cancer patients receiving anthracycline-based chemotherapy inKorea

83 ペリンドプリルエルブミン【Br J Clin Pharmacol. 82(2016)1647-1659】Determinants of angiotensin-convertingenzyme inhibitor (ACEI) intolerance and angioedema in the UK Clinical PracticeResearch Datalink

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84 バルプロ酸ナトリウム【第39回日本分子生物学会年会. (2016)】胎児期抗てんかん薬曝露マウスの生体でのけいれん感受性増加

85 バルプロ酸ナトリウム【American academy of Neurology. 87(2016)1943-1953】Cognition in school-agechildren exposed to levetiracetam,topiramate,or sodium valproate

86 ロキソプロフェンナトリウム水和物【医療薬学. 42(2016)717-726】国内自発報告データベースを用いたデフェラシロクスと他剤の併用による急性腎不全リスクのシグナル検出とケースコントロール研究による評価

87 リスペリドン【J Am Geriatr Soc. 64(2016)1203-1209】Antipsychotic drugs and risk of hip fracturein people aged 60 and older in Norway


【Fudan University Journal of Medical Sciences. 42(2015)743-748】Comparison of theincidence of vancomycin-induced nephrotoxicity in hospitalized children with orwithout concomitant piperacillin-tazobactam

89 ジゴキシン【Eur Heart J. 37(2016)202-203】Differential impacts of digoxin modulated by volumestatus on one-year mortality in patients with acute heart failure

90 ジゴキシン【Eur Heart J. 37(2016)795】Mortality and morbidity in heart failure patients exposedto digoxin: comprehensive data according to ejection fraction and atrial fibrillation in41881 patients

91 リツキシマブ（遺伝子組換え）【Am J Hematol. 91(2016)1002-1007】Impact of sarcopenia on treatment tolerance inUnited States veterans with diffuse large B-cell lymphoma treated with CHOP-based chemotherapy

92 プレドニゾロン【日本大腸肛門病会誌第69巻抄録号. 69(2016)A131】回腸嚢肛門管吻合術を施行した潰瘍性大腸炎症例におけるSSI（surgical site infection）発生因子の検討

93 テストステロンエナント酸エステル【BMJ. 355(2016)i5968】Testosterone treatment and risk of venousthromboembolism: population based case-control study

94 ピオグリタゾン塩酸塩・メトホルミン塩酸塩【Prostate Cancer Prostatic Dis. 19(2016)367-373】Tumor features and survival afterradical prostatectomy among antidiabetic drug users

95アログリプチン安息香酸塩・メトホルミン塩酸塩

【Prostate Cancer Prostatic Dis. 19(2016)367-373】Tumor features and survival afterradical prostatectomy among antidiabetic drug users

96 アスピリン・ランソプラゾール配合剤【Therap Adv Gastroenterol. 9(2016)806-814】Prediagnosis aspirin use and outcomesin a prospective cohort of esophageal cancer patients

97 アスピリン・ランソプラゾール配合剤【J Arthroplasty. 31(2016)2447-2451】Rate of Transfusions After Total KneeArthroplasty in Patients Receiving Lovenox or High-Dose Aspirin

98 アスピリン・ランソプラゾール配合剤【J Am Coll Cardiol. 68(2016)1116-1139】Duration of Dual Antiplatelet Therapy: ASystematic Review for the 2016 ACC/AHA Guideline Focused Update on Durationof Dual Antiplatelet Therapy in Patients With Coronary Artery Disease

99 アスピリン【Am J Gastroenterol. 111(2016)S418-S419】Higher mortality in patients withcoronary artery disease and gastrointestinal bleeding while on dual antiplatelettherapy with oral anticoagulants

100 ビソプロロールフマル酸塩【Fertil Steril. 106(2016)e75】Special research presentation: the association betweenantihypertensives and male infertility using insurance claims data

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101 クロピドグレル硫酸塩【Eur Heart J. 37(2016)1164】Determinants of high platelet reactivity in rapidmetabolizers with acute coronary syndrome

102 スコポラミン臭化水素酸塩水和物【Brain Res Bull. 127(2016)234-247】Scopolamine-induced greater alterations inneurochemical profile and increased oxidative stress demonstrated a better model ofdementia: A comparative study

103 ハロペリドールデカン酸エステル【JAMA Internal Medicine. (2016)E1-E9】Efficacy of Oral Risperidone, Haloperidol, orPlacebo for Symptoms of Delirium Among Patients in Palliative Care


【67th Annual Meeting of the American Association for the Study of Liver Diseases.63(2016)663A】Unusually high HCC rates among patients with HCV cirrhosis aftertreatment with direct acting antivirals

105 ソホスブビル【67th Annual Meeting of the American Association for the Study of Liver Diseases.63(2016)663A】Unusually high HCC rates among patients with HCV cirrhosis aftertreatment with direct acting antivirals

106 リドカイン【J Drugatol Drugs. 13(2014)1118-1122】Risk of Systemic Toxicity With TopicalLidocaine/Prilocaine: A Review

107 ジクロフェナクナトリウム【J Gastrointest Surg. 20(2016)776-782】Risk of anastomotic leakage withnonsteroidal anti-inflammatory drugs within an enhanced recovery program

108 アスピリン・ランソプラゾール配合剤【J Diabetes Res. (2016)1-8】Mean Daily Dosage of Aspirin and the Risk of IncidentAlzheimer's Dementia in Patients with Type 2 Diabetes Mellitus: A NationwideRetrospective Cohort Study in Taiwan

109 タムスロシン塩酸塩【Mil Med. 180(2015)355-360】Effects of alpha-blocker therapy on active dutymilitary and military retirees for benign prostatic hypertrophy on diabeticcomplications


111 ジゴキシン【Eur Heart J. 37(2016)300】Digoxin-amiodarone combination is associated withexcess all-cause mortality in patients with atrial fibrillation


113 インフリキシマブ（遺伝子組換え）【Ann Rheum Dis. 71(2012)869-874】The influence of anti-TNF therapy uponincidence of keratinocyte skin cancer in patients with rheumatoid arthritis:longitudinal results from the British Society for Rheumatology Biologics Register

114 イストラデフィリン【社内資料】レボドパ含有製剤で治療中の患者のうち、ウェアリングオフ現象を併発している中等度から重度のパーキンソン病患者を対象としたイストラデフィリン第3相無作為化二重盲検試験

115 クロピドグレル硫酸塩【Eur Heart J. 37(2016)1161】Preadmission platelet inhibitor use and short-termmortality from stroke: A nationwide cohort study

116 ラベプラゾールナトリウム【Infect Control Hosp Epidemiol. 36(2015)452-460】Risk Factors for RecurrentClostridium difficile Infection: A Systematic Review and Meta-Analysis

117 ラベプラゾールナトリウム【Expert Opin Drug Saf. 15(2016)1589-1595】Proton pump inhibitors and risk ofClostridium difficile infection: a multi-country study using sequence symmetryanalysis

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118 ジゴキシン【Eur Heart J. 37(2016)300】Digoxin-amiodarone combination is associated withexcess all-cause mortality in patients with atrial fibrillation



121 アスピリン・ランソプラゾール配合剤【Anesthesiology. 125(2016)1121-1129】Perioperative Aspirin for Prevention ofVenous Thromboembolism: The PeriOperative ISchemia Evaluation-2 Trial and aPooled Analysis of the Randomized Trials

122 乾燥弱毒生麻しんワクチン【Medicine. 95(2016)e4738】Waning of vaccine-induced immunity to measles in kidneytransplanted children

123ダビガトランエテキシラートメタンスルホン酸塩

【CMAJ. (2016)1-8】Association between statin use and ischemic stroke or majorhemorrhage in patients taking dabigatran for atrial fibrillation

124 アザチオプリン【Ann Rheum Dis. 71(2012)869-874】The influence of anti-TNF therapy uponincidence of keratinocyte skin cancer in patients with rheumatoid arthritis:longitudinal results from the British Society for Rheumatology Biologics Register

125 乾燥人血液凝固因子抗体迂回活性複合体【Blood. 128(2016)4952】Synergistic Effects of a Procoagulant Bispecific Antibodyand Rescue Therapies on Thrombin Generation- a Potential Safety Risk

126 エスシタロプラムシュウ酸塩【Pediatrics. 138(2016)1-10】Neonatal Morbidity After Maternal Use ofAntidepressant Drugs During Pregnancy

127 イミダプリル塩酸塩【Br J Clin Pharmacol. 82(2016)1647-1659】Determinants of angiotensin-convertingenzyme inhibitor (ACEI) intolerance and angioedema in the UK Clinical PracticeResearch Datalink

128 アスピリン・ランソプラゾール配合剤【PLOS One. 12(2015)1-10】Aspirin compared to low intensity anticoagulation inpatients with non-valvular atrial fibrillation. a systematic review and meta-analysis

129 ピオグリタゾン塩酸塩・メトホルミン塩酸塩【Agence nationale de securite du medicament et des produits de sante. (2016)1-58】Exposition aux incretinomimetiques et risque de cancer du pancreas chez lespatients atteints de diabete de type 2


【Agence nationale de securite du medicament et des produits de sante. (2016)1-58】Exposition aux incretinomimetiques et risque de cancer du pancreas chez lespatients atteints de diabete de type 2

131 プレドニゾロン

【40th World Congress of the International College of Surgeons 62nd AnnualCongress of the International College of Surgeons Japan Section Japan SectionProgram　and Abstracts 2016. (2016)452】Risk factors associated with postoperativeinfectious complications in patients with ulcerative colitis


【Allergy Asthma Proc. 37(2016)9-17】Adrenal suppression by inhaled corticosteroidsin patients with asthma: A systematic review and quantitative analysis

133 沈降ジフテリア破傷風混合トキソイド【Trans R Soc Trop Med Hyg. 110(2016)570-581】Is diphtheria-tetanus-pertussis(DTP) associated with increased female mortality? A meta-analysis testing thehypotheses of sex-differential non-specific effects of DTP vaccine

134 ピオグリタゾン塩酸塩・メトホルミン塩酸塩【Expert Opin Pharmacother. 16(2015)2719-2725】Effects of metformin on clinicaloutcome in diabetic patients with advanced HCC receiving sorafenib

8


【Expert Opin Pharmacother. 16(2015)2719-2725】Effects of metformin on clinicaloutcome in diabetic patients with advanced HCC receiving sorafenib

136 カペシタビン【JAMA Oncol. (2016)】Association of Proton Pump Inhibitors and CapecitabineEfficacy in Advanced Gastroesophageal Cancer Secondary Analysis of the TRIO-013/LOGiC Randomized Clinical Trial

137 アスピリン・ランソプラゾール配合剤【Fertil Steril. 105(2016)1241-1246】 Subchorionic hematomas are increased in earlypregnancy in women taking low-dose aspirin

138 ラベプラゾールナトリウム【肺癌. 56(2016)627】原発性肺腺癌におけるMCT4発現とスタチンとプロトンポンプ阻害剤との関連性

139 ラベプラゾールナトリウム【日本消化器病学会大会. (2015)A849】胃底腺ポリープに及ぼすPPIの影響

140 リツキシマブ（遺伝子組換え）【Cochrane Database Syst Rev. 11(2012)】Rituximab, ofatumumab and othermonoclonal anti-CD20 antibodies for chronic lymphocytic leukaemia

141 ハロペリドールデカン酸エステル【Eur Neuropsychopharmacol. 26(2016)1390-1400】Comparative risk of death in olderadults treated with antipsychotics: A population-based cohort study

142 クロピドグレル硫酸塩

【Acta Biomed. 86(2015)162-169】Prevalence, main determinants, and early outcomeof patients with atrial fibrillation hospitalized with ischemic stroke: evaluation of thevalue of risk assessment scores for predicting risk of stroke or major bleedingfollowing

143 ラコサミド【Ther Drug Monit. 36(2014)494-498】 Lacosamide serum concentrations in adultpatients with epilepsy: The influence of gender, age, dose, and concomitantantiepileptic drugs

144 ラコサミド【Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 159(2015)394-399】Theeffect of lacosamide on bone tissue in orchidectomised male albino Wistar rats

145 プレドニゾロン【J Pharmacol Sci. 132(2016)187-191】Dentin hypersensitivity-like tooth pain seen inpatients receiving steroid therapy: An exploratory study

146 エスシタロプラムシュウ酸塩【JAMA Neurology. (2016)E1-E8】Association of Selective Serotonin ReuptakeInhibitors With the Risk for Spontaneous Intracranial Hemorrhage.

147 クリゾチニブ【社内資料】OPHTHALMOLOGY AND SAFETY ANALYSES IN PATIENTS WITHADVANCED NSCLC

148 ペニシラミン【Rheumatology. 55(2016)1594-1600】Disease-modifying anti-rheumatic drugs andnon-melanoma skin cancer in inflammatory arthritis patients: a retrospective cohortstudy

149 エソメプラゾールマグネシウム水和物【Fertil Steril. 106(2016)1666-1672】Are proton-pump inhibitors harmful for thesemen quality of men in couples who are planning pregnancy?

150 オメプラゾール【Fertil Steril. 106(2016)1666-1672】Are proton-pump inhibitors harmful for thesemen quality of men in couples who are planning pregnancy?

151 オメプラゾール【Ann Pharmacother. 51(2017)66-71】Proton Pump Inhibitors: Risk for Myopathy?

9

152 ハロペリドール【Eur Neuropsychopharmacol. 26(2016)1390-1400】Comparative risk of death in olderadults treated with antipsychotics: A population-based cohort study

153 プロゲステロン【Arch Med Res. 47(2016)419-426】Intracellular Progesterone Receptor Mediates theIncrease in Glioblastoma Growth Induced by Progesterone in the Rat Brain

154 非ピリン系感冒剤（４）【Br J Clin Pharmacol. 83(2017)180-191】Systematic review and meta-analysis ofclinical outcomes of early caffeine therapy in preterm neonates

155 ハロペリドールデカン酸エステル【Eur Neuropsychopharmacol. 26(2016)1390-1400】Comparative risk of death in olderadults treated with antipsychotics: A population-based cohort study

156 ラベプラゾールナトリウム【Infect Control Hosp Epidemiol. 37(2016)1408-1417】Assessing the Risk of Hospital-Acquired Clostridium Difficile Infection With Proton Pump Inhibitor Use: A Meta-Analysis

157 トラネキサム酸【N Engl J Med. 376(2017)136-148】Tranexamic Acid in Patients UndergoingCoronary-Artery Surgery

158 トラネキサム酸【Seizure. 36(2016)70-73】Tranexamic acid-associated seisure: A meta-analysis

159 デキストロメトルファン含有一般用医薬品【Pharmacoepidemiol Drug Saf. 25(2016)590-591】The risk of depression, euphoricmood and sedation with the use of dextromethorphan in different indications. Resultsfrom a systematic review and meta-analysis of randomised clinical trials

160 オキシブチニン塩酸塩【Menopause. 23(2016)1214-1221】 Extended-release oxybutynin therapy forvasomotor symptoms in women: A randomized clinical trial

161 非ピリン系感冒剤（４）【Br J Clin Pharmacol. 83(2017)180-191】Systematic review and meta-analysis ofclinical outcomes of early caffeine therapy in preterm neonates

162 アロプリノール【Eur J Cancer Prev. 25(2016)216-223】Allopurinol and the incidence of bladdercancer: a Taiwan national retrospective cohort study

163 ジクロフェナクナトリウム【BMC Musculoskelet Disord. 17(2016)201】Non-steroidal anti-inflammatory drugsand the risk of a second hip fracture: a propensity-score matching study

164 インフリキシマブ（遺伝子組換え）【Arthritis and Rheumatology. 68(2016)2155-2156】Ustekinumab, apremilast, TNFi andthe risk for hospitalized infection in patients with psoriasis and psoriatic arthritis

165 ピオグリタゾン塩酸塩【BMJ Open. 7(2017)e013927】Pioglitazone and cardiovascular outcomes in patientswith insulin resistance, pre-diabetes and type 2 diabetes: a systematic review andmeta-analysis

166 プラバスタチンナトリウム【Drug Metab Pharmacokinet. 31(2016)467-470】A possible role for HLA-DRB1*04:06in statin-related myopathy in Japanese patients

167 ラベプラゾールナトリウム【J Gen Intern Med. 31(2016)364-371】Defining Appropriate Use of Proton-PumpInhibitors Among Medical Inpatients

168 ハロペリドール【Pharmacoepidemiology and Drug Safety. 25(2016)588-589.】Use of antipsychoticsand risk of recurrent stroke events: A population-based retrospective cohort studyin Taiwan

10

169 無水カフェイン【Int J Gynaecol Obstet. 130(2015)116-122】A meta-analysis of risk of pregnancyloss and caffeine and coffee consumption during pregnancy


【Pharmacotherapy. 36(2016)1217-1228】Is the Combination of Piperacillin-Tazobactam and Vancomycin Associated with Development of Acute Kidney Injury?A Meta-analysis

171 インスリン　アスパルト（遺伝子組換え）【Diabetes Res Clin Pract. 123(2017)165-172】QT prolongation caused by insulin-induced hypoglycaemia - An interventional study in 119 individuals

172 リスペリドン【Eur J Clin Pharmacol. 73(2017)233-239】Real-world risk of diabetes withantipsychotic use in older New Zealanders: a case-crossover study

173 バルプロ酸ナトリウム【Pharmacoepidemiol Drug Saf. 25(2016)585】Is use of antiepileptic drugs associatedwith an increased cataract risk? A case-control analysis

174 クロナゼパム【Pharmacoepidemiol Drug Saf. 25(2016)585】Is use of antiepileptic drugs associatedwith an increased cataract risk? A case-control analysis

175 オセルタミビルリン酸塩【平成28年度第33回日本薬学会九州支部大会. (2016)48】オセルタミビル及びその代謝物投与によるマウスの行動について（第5報）.

176 リトドリン塩酸塩【第10回日本早産予防研究会学術集会. (2016）】双胎妊娠における肺水腫は、塩酸リトドリンの総投与量に依存して発症率が高まる

177 ブロナンセリン【Br J Clin Pharmacol. 81(2016)773-738】Antidepressants and antipsychoticsclassified with torsades de pointes arrhythmia risk and mortality in older adults - aSwedish nationwide study

178 ブロナンセリン【Pharmacoepidemiol Drug Saf. 25(2016)363】Risk of mortality associated withantipsychotic monotherapy and polypharmacy among community-dwelling personswith alzheimer's disease

179 Ａ型ボツリヌス毒素【Neurourol Urodyn. 36(2017)142-147】Predictive factors of adverse events afterintravesical suburothelial onabotulinumtoxina injections for overactive bladdersyndrome-A real-life practice of 290 cases in a single center

180 ペルゴリドメシル酸塩【Eur J Clin Pharmacol. 73(2017)99-103】Ergot and non-ergot dopamine agonists andheart failure in patients with Parkinson's disease

181 プロゲステロン【Thromb Res. 139(2016)29-37】factors for incident venous thromboembolism inactive cancer patients: A population based case-control study

182 アミオダロン塩酸塩【Acta Histochem. 118(2016)271-277】Effects of chronic amiodarone treatment onrat testis

183 リドカイン【Paediatr Anaesth. 26(2016)337-344】Lignocaine topicalization of the pediatricairway

184 ハロペリドール【Pharmacoepidemiol Drug Saf. 25(2016)262】Comparative safety of antipsychoticmedications in hospitalized myocardial infarction patients(Abstract Number: 447)

185 アスピリン【J Clin Gastroenterol. 50(2016)134-140】Impact of diagnostic delay and other riskfactors on eosinophilic esophagitis phenotype and esophageal diameter

11

186 ハロペリドール【Pharmacoepidemiol Drug Saf. 25(2016)363】Risk of mortality associated withantipsychotic monotherapy and polypharmacy among community-dwelling personswith alzheimer's disease

187 ラベプラゾールナトリウム【Clin Infect Dis. (2016)】Use of proton pump inhibitors and the risk of listeriosis. Anationwide registry-based case-control study


【Journal of Diabetes. 8(2016)279-285】Risk of overall mortality and cardiovascularevents in patients with type 2 diabetes on dual drug therapy including metformin: Alarge database study from the Cleveland Clinic

189 エソメプラゾールマグネシウム水和物【Gastroenterology. 152(2017)134-141】Proton Pump Inhibitors Increase Risk forHepatic Encephalopathy in Patients With Cirrhosis in A Population Study

190 オメプラゾール【Gastroenterology. 152(2017)134-141】Proton Pump Inhibitors Increase Risk forHepatic Encephalopathy in Patients With Cirrhosis in A Population Study

191 クロピドグレル硫酸塩【J Stroke Cerebrovasc Dis. 25(2016)2610-2618】Aspirin and Clopidogrel InhibitAneurysm Healing after HydroCoil Implantation in External Carotid Artery AneurysmModel

192 デキサメタゾン【第69回日本薬理学会西南部会. (2016)】デキサメタゾンの局所投与は放射線誘発口腔粘膜炎を増悪させる

193 トレチノイン【Naunyn-Schmiedeberg's archives of pharmacology 389(2016)327-337】All-transretinoiu acid potentiates cisplatin- induced kidney injury in rats: impact of retinoicacid signaling pathway

194 カベルゴリン【Eur J Clin Pharmacol. 73(2017)99-103】Ergot and non-ergot dopamine agonists andheart failure in patients with Parkinson's disease

195 アセトアミノフェン【J Toxicol Sci. 150(2016)178-189】V.Intrauterine Exposure to Paracetamol andAniline Impairs Female Reproductive Development by Reducing Follicle Reserves andFertility

196 オメプラゾール【Gastroenterology. 152(2017)134-141】Proton Pump Inhibitors Increase Risk forHepatic Encephalopathy in Patients With Cirrhosis in A Population Study

197 アロプリノール【Oncotarget. 7(2016)81870-81879】Impact of HLA-B*58:01 allele and allopurinol-induced cutaneous adverse drug reactions: evidence from 21 pharmacogeneticstudies

198 ボルテゾミブ【Anticancer Resarch. 36(2016)6655-6662】High Risk of Tumor Lysis Syndrome inSymptomatic Patient with Multiple Myeloma with Renal Dysfunction Treated withBortezomib

199 コリスチンメタンスルホン酸ナトリウム【Wien Klin Wochenschr. 128(2016)614-619】Variables determining the developmentof colistin-associated renal impairment

200 オセルタミビルリン酸塩【Epigenetics. 20(2009)619-621】.Oseltamivir and abnormal behaviors: true or　not?.

201 オセルタミビルリン酸塩【Epigenetics. 21(2010)915-916】Oseltamivir and abnormal behavior

202 ヒト絨毛性性腺刺激ホルモン【Mol Carcinog. 56(2017)359-370】Gonadotropin and Tumorigenesis: Direct andIndirect Effects on Inflammatory and Immunosuppressive Mediators and Invasion

12

203 ペメトレキセドナトリウム水和物【J Clin Oncol. 34(2016)2969-2979】Nivolumab in combination with platinum-baseddoublet chemotherapy for first-line treatment of advanced non-small-cell lungcancer

204 オセルタミビルリン酸塩【Cardiovasc Toxicol. 13(2013)234-243】Cardiohemodynamic and　electrophysiologicaleffects of anti-influenza drug oseltamivir in vivo and in　vitro

205 オセルタミビルリン酸塩【Drug Metab Dispos. 36(2008)427-434】P-glycoprotein restricts the penetration ofoseltamivir across the blood-brain barrier

206 オセルタミビルリン酸塩【Neurosci Lett. 495(2011)187-191】Determination of radioactivity in infant, juvenileand adult rat brains after injection of anti-influenza drug [11C]oseltamivir using PETand autoradiography

207 オセルタミビルリン酸塩【Biol Pharm Bull. 36(2013)1650-1652】Electrophysiological effects of an anti-influenza drug oseltamivir on the guinea-pig atrium:　comparison with those ofpilsicainide

208 ラベプラゾールナトリウム【第70回国立病院総合医学会抄録集. (2016)613】メタロ-β-ラクタマーゼ産生腸内細菌科細菌保菌のリスク因子解析

209 アスピリン・ランソプラゾール配合剤【Vascul Pharmacol, 87(2016)66-69】Dipyrone comedication in aspirin treated strokepatients impairs outcome

210 無水カフェイン【Public Health Nutr. 19(2016)1233-1244】 Maternal caffeine intake during pregnancyand risk of pregnancy loss: a categorical and dose-response meta-analysis ofprospective studies

211 メチルジゴキシン【J Investig Med. 64(2016)924】Digitalis increases the 30-day readmission rate inpatients with heart failure and reduced ejection fraction

212 ジゴキシン【J Investig Med. 64(2016)924】Digitalis increases the 30-day readmission rate inpatients with heart failure and reduced ejection fraction

213 バンコマイシン塩酸塩【Ophthalmology. 122(2015)1438-1451】Vancomycin-Associated HemorrhagicOcclusive Retinal Vasculitis

214 フルボキサミンマレイン酸塩【第22回日本薬剤疫学会学術総会　プログラム・抄録集. (2016)96-97】レセプトデータを用いた妊娠中の精神疾患とその治療薬が出生児に与える影響の解析

215 ハロペリドールデカン酸エステル【Chest. 150(2016)1233-1241】Antipsychotic Use and Risk of Hospitalization orDeath Due to Pneumonia in Persons With and Those Without Alzheimer Disease

216 リスペリドン【Chest. 150(2016)1233-1241】Antipsychotic Use and Risk of Hospitalization orDeath Due to Pneumonia in Persons With and Those Without Alzheimer Disease

217 フルチカゾンプロピオン酸エステル【Eur Respir J. 48(2016)PA4223】Is treatment with inhaled corticosteroids in asthmaassociated with hospitalisations because of pneumonia?

218 パロキセチン塩酸塩水和物【JAMA Psychiatry. 73(2016)1163-1170】Association of Selective SerotoninReuptake Inhibitor Exposure During Pregnancy With Speech, Scholastic, and MotorDisorders in Offspring

219 ドセタキセル【第54回日本癌治療学会学術集会. (2016)】当院における過去5年間の去勢抵抗性前立腺癌に対するドセタキセル療法の治療成績

13


【Cancer Epidemiol Biomarkers Prev. 25(2016)1464-1473】Postmenopausal HormoneTherapy and Breast Cancer Prognostic Characteristics: A Linkage betweenNationwide Registries

221 カルバゾクロム・アスコルビン酸配合剤【Free Radic Biol Med. 91(2016)204-214】Antioxidant supplementation acceleratescachexia development by promoting tumor growth in C26 tumor-bearing mice

222 エストラジオール吉草酸エステル【Cancer Epidemiol Biomarkers Prev. 25(2016)1464-1473】Postmenopausal HormoneTherapy and Breast Cancer Prognostic Characteristics: A Linkage betweenNationwide Registries

223 ハロペリドールデカン酸エステル【Chest. 150(2016)1233-1241】Antipsychotic Use and Risk of Hospitalization orDeath Due to Pneumonia in Persons With and Those Without Alzheimer Disease

224 クエチアピンフマル酸塩【Am J Psychiatry. (2016)1-13】Morbidity and Mortality Associated With MedicationsUsed in the Treatment of Depression: An Analysis of Cases Reported to U.S. PoisonControl Centers, 2000-2014

225 メトトレキサート【Arthritis and Rheumatology. 68(2016)4167-4168】Risk of infections in juvenileidiopathic arthritis patients treated with biologic agents and/or methotrexate: resultsfrom pharmachild registry

226 フェンタニルクエン酸塩【Crit Care Med. 45(2017)e7-e15】Patient, process, and system predictors ofiatrogenic withdrawal syndrome in critically ill children

227 アルプロスタジル　アルファデクス【J Perinat Neonatal Nurs. 30(2016)73-79】Complications of Long-TermProstaglandin E1 Use in Newborns With Ductal-Dependent Critical Congenital HeartDisease

228 Ｂ型ボツリヌス毒素【第22回日本薬剤疫学会学術総会　プログラム・抄録集. (2016)108-109】JADERを用いた薬剤性嚥下障害の発症時期に及ぼす要因の探索

229 フロセミド【Medical Practice. 34(2017)109-112】知っておくべき心不全の最新治療　利尿薬の正しい使いかたと注意点

230 ガンシクロビル【Pediatr Drugs. 19(2017)59-67】Identifying High-Risk Medications Associated withAcute Kidney Injury in Critically Ill Patients: A Pharmacoepidemiologic Evaluation

231 Ａ型ボツリヌス毒素【Dev Med Child Neurol. 59(2017)329-334】Adverse drug reactions of botulinumneurotoxin type A in children with cerebral palsy: a pharmaco-epidemiological studyin VigiBase

232 リスペリドン【Prog Neuropsychopharmacol Biol Psychiatry. 75(2017)35-44】In utero exposure toatypical antipsychotic drug, risperidone: Effects on fetal neurotoxicity in hippocampalregion and cognitive impairment in rat offspring

233 ドキソルビシン塩酸塩

【Breast Cancer Res Treat. 161(2017)363-373】Risk of acute myeloid leukemia andmyelodysplastic syndrome among older women receiving anthracyclme-basedadjuvant chemotherapy for breast cancer on Modern Cooperative GroupTrials(Alliance A151511)

234インフルエンザＨＡワクチン細胞培養インフルエンザワクチン（Ｈ５Ｎ１株）

【Vaccine. 35(2017)687-693】Negative impact of prior influenza vaccination oncurrent influenza vaccination among people infected and not infected in priorseason:A test-negative case-control study in Japan

235 テストステロンエナント酸エステル【Clinical and applied thrombosis/hemostasis. 22(2016)548-553】Thrombophilia in 67Patients With Thrombotic Events After Starting Testosterone Therapy

236 炭酸リチウム【J Clin Psychiatry. 304(2013)F300-F307】Chronic interstitial fibrosis in the ratkidney induced by long-term (6-mo) exposure to lithium

14

237 エソメプラゾールマグネシウム水和物【FARMACIA. 64(2016)262-267】PROLONGED USE OF PROTON POMP INHIBITORSAND COGNITIVE FUNCTION IN OLDER ADULTS

238 オメプラゾール【FARMACIA. 64(2016)262-267】PROLONGED USE OF PROTON POMP INHIBITORSAND COGNITIVE FUNCTION IN OLDER ADULTS

239 オメプラゾール【J Gastroenterol Hepatol. (2017)】Dementia, cognitive impairment and proton pumpinhibitor therapy - a systematic review

240 エソメプラゾールマグネシウム水和物【J Gastroenterol Hepatol. (2017)】Dementia, cognitive impairment and proton pumpinhibitor therapy - a systematic review

241 ボセンタン水和物【Eur J Clin Pharmacol. 73(2017)267-278】Association of oral endothelin receptorantagonists with risks of cardiovascular events and mortality: meta-analysis ofrandomized controlled trials


【PLOS One. 11(2016)e0167934】DAAs Rapidly Reduce Inflammation but IncreaseSerum VEGF Lelel: A Rationale for Tumor Risk during Anti-HCV Treatment

243 ソホスブビル【PLOS One. 11(2016)e0167934】DAAs Rapidly Reduce Inflammation but IncreaseSerum VEGF Lelel: A Rationale for Tumor Risk during Anti-HCV Treatment

244 テストステロン含有一般用医薬品【Clin Endocrinol (Oxf). 85(2016)436-443】Testosterone therapy, association with age,initiation and mode of therapy with cardiovascular events: a systematic review

245 エスシタロプラムシュウ酸塩【Ann Pharmacother. 51(2017)226-231】Risk of Bleeding in Patients on Full-DoseEnoxaparin With Venous Thromboembolism and Selective Serotonin ReuptakeInhibitors


【Eur Respir J. 48(2016)PA4223】Is treatment with inhaled corticosteroids in asthmaassociated with hospitalisations because of pneumonia?

247 レボフロキサシン水和物【Eur Respir J. 48(2016)PA3639】 Early life antibiotic exposure is associated with anincreased risk of allergy

248 ジクロフェナクナトリウム【Eur Respir J. 48(2016)OA3330】Non-steroidal anti-inflammatory drugs may worsenthe course of community-acquired pneumonia : A cohort study

249 沈降ジフテリア破傷風混合トキソイド【Pharmacoepidemiol Drug Saf. 26(2017)17-25】Vaccination and unexplained suddendeath risk in Taiwanese infants

250 クロピドグレル硫酸塩【J Am Coll Cardiol. (2015)8100】A Meta-analysis of 43,432 patients: ConcomitantUse of Proton pump inhibitor With Clopidogrel is Associated with Increased Deathand Myocardial infarction in patients receiving percutaneous coronary intervention

251 インフリキシマブ（遺伝子組換え）【J Invest Dermatol. 137(2017)313-321】Infections in Moderate to Severe PsoriasisPatients Treated with Biological Drugs Compared to Classic Systemic Drugs:Findings from the BIOBADADERM Registry

252 ジゴキシン【Int J Cardiol. 228(2017)214-218】The impact of digoxin on mortality in patients withchronic systolic heart failure: A propensity-matched cohort study

253 チカグレロル【Am J Med. (2017)1-2】Excess Ticagrelor Mortality in the Food and DrugAdministration Adverse Event Reporting System: Time to Recount PLATO TrialDeaths.

15

254 ワルファリンカリウム【Circ J. 81(2017)158-164】Clinical Significance of Hematuria in Atrial Fibrillation WithOral Anticoagulation Therapy.

255 パゾパニブ塩酸塩【Circulation. 135(2017)815-817】Association Between Aortic Dissection andSystemic Exposure of Vascular Endothelial Growth Factor Pathway Inhibitors in theJapanese Adverse Drug Event Report Database


257 ラベプラゾールナトリウム

【BMC Cardiovasc Disord. 17(2017)】Is the concomitant use of clopidogrel and ProtonPump Inhibitors still associated with increased adverse cardiovascular outcomesfollowing coronary angioplasty?: a systematic review and meta-analysis of recentlypublished studies (2012 - 2016)

258 ラベプラゾールナトリウム【Medicine. 95(2016)e4089】Association between gastroesophageal reflux disease andcoronary heart disease: A nationwide population-based analysis

259 エスシタロプラムシュウ酸塩【J Head Trauma Rehabil. 32(2017)E42-E49】Risk of Stroke Among Older MedicareAntidepressant Users With Traumatic Brain Injury.

260インスリン　グラルギン（遺伝子組換え）［後続１］

【Acta Oncol. 55(2016)851-858】Insulin glargine use and breast cancer risk:Associations with cumulative exposure

261 ゲメプロスト【Am J Obstet Gynecol. 216(2017)165.e1-165.e8】Risk factors for complete uterinerupture

262 パロキセチン塩酸塩水和物【JAMA Psychiatry. 73(2016)1163-1170】Association of selective serotonin reuptakeinhibitor exposure during pregnancy with speech, scholastic, and motor disorders inoffspring


264 レベチラセタム【Rev Neurol. 173(2017)62-66】Newer anti-epileptic drugs, vitamin status andneuropathy: A cross-sectional analysis

265 レベチラセタム【Rev Neurol. 173(2017)62-66】Newer anti-epileptic drugs, vitamin status andneuropathy: A cross-sectional analysis

266 イブルチニブ【Blood. (2017)】Ventricular Arrhythmias and Sudden Death in Patients TakingIbrutinib

267 ダルナビル　エタノール付加物【The Conference on Retroviruses and Opportunistic Infections. (2017)】Associationbetween cardiovascular disease contemporarily used protease inhibitors.

268 ダルナビル　エタノール付加物・コビシスタ【The Conference on Retroviruses and Opportunistic Infections. (2017)】Associationbetween cardiovascular disease contemporarily used protease inhibitors.

269 ソホスブビル【EASL Liver Conference. (2017)】Recurrence of Hepatocellular Carcinoma (HCC)Following Direct-Acting Antiviral (DAA) Therapy for Hepatitis C from the HCV-TARGET Study


【EASL Liver Conference. (2017)】Recurrence of Hepatocellular Carcinoma (HCC)Following Direct-Acting Antiviral (DAA) Therapy for Hepatitis C from the HCV-TARGET Study

16

271 イブプロフェン【Stroke. 47(2016)1045-1052】Paracetamol, ibuprofen, and recurrent majorcardiovascular and major bleeding events in 19 120 patients with recent ischemicstroke

272 パロキセチン塩酸塩水和物【JAMA Neurology. 74(2017)173-180】Association of selective serotonin reuptakeinhibitors with the risk for spontaneous intracranial hemorrhage

273 非ピリン系感冒剤（４）【Stroke. 47(2016)1045-1052】Paracetamol, ibuprofen, and recurrent majorcardiovascular and major bleeding events in 19 120 patients with recent ischemicstroke

274 アスピリン【J Am Coll Cardiol. 69(2017)603-612】Enteric Coating and AspirinNonresponsiveness in Patients With Type 2 Diabetes Mellitus

275 ラベプラゾールナトリウム【第13回日本消化管学会総会学術集会プログラム・抄録集. (2017)238】PPI長期内服者患者の高ガストリン血症における性差

276 ラベプラゾールナトリウム【Pharmacogenet Genomics. 27(2017)83-88】Common single nucleotidepolymorphisms in transient receptor potential melastatin type 6 increase the risk forproton pump inhibitor-induced hypomagnesemia: a case-control study

277 塩酸セルトラリン【Inflamm Bowel Dis. 19(2013)411-417】Epidemiological risk factors in microscopiccolitis: a prospective case-control study

278 ランソプラゾール【J Allergy Clin Immunol. 16(2016)】Acid-suppressive medications during pregnancyand risk of asthma and allergy in children: A systematic review and meta-analysis

279 ピオグリタゾン塩酸塩【Medicine. 95(2016)1-5】Long-term effects of pioglitazone on first attack ofischemic cerebrovascular disease in older people with type 2 diabetes A case-control study in Taiwan

280 ドキソルビシン塩酸塩【Clin Cancer Res. 23(2017)43-51】Genome-Wide Association Study forAnthracyciine-induced Congestive Heart Faiiure

281 アトルバスタチンカルシウム水和物【Br J Dermatol. 175(2016)1183-1194】Statin use and the risk of herpes zoster: anested case-control study using primary care data from the U.K. Clinical ResearchPractice Datalink

282 ラミブジン【WHO Pharmaceuticals Newsletter. 1(2017)23-28】 Lamivudine and hearingdecreased

283 ロスバスタチンカルシウム【Br J Dermatol. 175(2016)1183-1194】Statin use and the risk of herpes zoster: anested case-control study using primary care data from the U.K. Clinical ResearchPractice Datalink

284 カンデサルタン　シレキセチル【Stroke. 45(2014)3440-3442】Blood pressure-lowering treatment with candesartan inpatients with acute hemorrhagic stroke

285 ピオグリタゾン塩酸塩【DTB Select. 3(2017)27】Pioglitazone and cardiovascular outcomes

286 イリノテカン塩酸塩水和物【Invest New Drugs. 35(2017)68-78】A phase 1 study combining the HER3 antibodyseribantumab (MM-121) and cetuximab with and without irinotecan

287 パロキセチン塩酸塩水和物【Am J Kidney Dis. 69(2017)87-96】Second‐Generation Antidepressants andHyponatremia Risk：A Population‐Based Cohort Study of Older Adults

17

288 トラネキサム酸【N Engl J Med. 376(2017)136-148】Tranexamic Acid in Patients UndergoingCoronary-Artery Surgery

289 クエチアピンフマル酸塩【Eur J Clin Pharmacol. 73(2017)233-239】Real-world risk of diabetes withantipsychotic use in older New Zealanders: a case-crossover study

290 クラリスロマイシン【BMJ Open. 7(2017)e013398】Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibioticsprescribed for respiratory tract infections: A retrospective cohort study

291 シルデナフィルクエン酸塩【Tissue Cell. (2017)】Effect of chronic administration of sildenafil citrate (Viagra) onthe histology of the retina and optic nerve of adult male rat

292 ゾルピデム酒石酸塩【J Clin Pharmacol. 57(2017)376-381】Use of Zolpidem and Risk of AcutePyelonephritis in Women: A Population-Based Case-Control Study in Taiwan

293 クロピドグレル硫酸塩【Int J Cardiol. 227(2017)305-311】Can TAVI patients receive aspirin monotherapy aspatients after surgical aortic bioprosthesis implantation? Data from the PolishRegistry-POL-TAVI

294 クロピドグレル硫酸塩【Circulation. 135(2017)21-33】Genetic polymorphisms and clopidogrel efficacy foracute ischemic stroke or transient ischemic attack: A systematic review and meta-analysis

295スルバクタムナトリウム・アンピシリンナトリウム

【J Pediatr. 181(2017)289-293】Antibiotic exposure and risk for death orbronchopulmonary dysplasia in very low birth weight infants

296 バルプロ酸ナトリウム【Epilepsia. 58(2017)274-281】Malformation risk of antiepileptic drug exposure duringpregnancy in women with epilepsy: Results from a pregnancy registry in South India

297 エソメプラゾールマグネシウム水和物【Circulation. 8(2015)】Proton Pump Inhibitors, Platelet Reactivity, and CardiovascularOutcomes After Drug-Eluting Stents in Clopidogrel-Treated Patients The ADAPT-DES Study

298 オメプラゾール【Circulation. 8(2015)】Proton Pump Inhibitors, Platelet Reactivity, and CardiovascularOutcomes After Drug-Eluting Stents in Clopidogrel-Treated Patients The ADAPT-DES Study

299 フェニトイン【European Journal of Hospital Pharmacy. 22(2015)A92】Should patients of thai, hanchinese and hong kong chinese origin be tested for the HLA-B*1502 allele prior tophenytoin treatment?

300 フェニトイン・フェノバルビタール【European Journal of Hospital Pharmacy. 22(2015)A92】Should patients of thai, hanchinese and hong kong chinese origin be tested for the HLA-B*1502 allele prior tophenytoin treatment?

301 アナストロゾール【Br J Clin Pharmacol. 83(2017)562-571】Polymorphisms in ABCB1 and CYPJ9AJgenes affect anastrozole plasma concentrations and clinical outcomes inpostmenopausal breast cancer patients

302 ゾルピデム酒石酸塩【J Clin Pharmacol. 57(2017)376-381】Use of zolpidem and risk of acutepyelonephritis in women: A population-based case-control study in Taiwan

303ランソプラゾール・アモキシシリン水和物・クラリスロマイシン

【BMJ Open. 7(2017)e013398】Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibioticsprescribed for respiratory tract infections: A retrospective cohort study

304ボノプラザンフマル酸塩・アモキシシリン水和物・クラリスロマイシン

【BMJ Open. 7(2017)e013398】Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibioticsprescribed for respiratory tract infections: A retrospective cohort study

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305コンドロイチン硫酸エステルナトリウム含有一般用医薬品

【Arthritis and Rheumatology. 69(2017)77-85】Combined treatment with chondroitinsulfate and glucosamine sulfate shows no superiority over placebo for reduction ofjoint pain and functional impairment in patients with knee osteoarthritis: A six-monthmulticenter, randomized, double-blind, placebo-controlled clinical trial

306 インスリン　ヒト（遺伝子組換え）【Cardiovasc Diabetol. 15(2016)1-10】Correlation between insulin-induced estrogenreceptor methylation and atherosclerosis

307 ハロペリドール【JAMA Internal Medicine. 177(2017)34-42】Efficacy of oral risperidone, haloperidol,or placebo for symptoms of delirium among patients in palliative care: A randomizedclinical trial

308 フロセミド【日本産科婦人科学会雑誌. 69(2017)869】フロセミドの妊娠への影響についての検討

309 ニボルマブ（遺伝子組換え）【社内資料】ONO-4578及びニボルマブのカニクイザルにおける併用投与による4週間反復投与毒性試験及び4週間回復性試験

310 ソホスブビル【APASL. 11(2017)page S1043】Comparison of SVR and Incidence of HCC betweenDAA with and without IFN in HCV Related Liver Diseases


【APASL. 11(2017)page S1043】Comparison of SVR and Incidence of HCC betweenDAA with and without IFN in HCV Related Liver Diseases

312 メトホルミン塩酸塩【Hepatol Int. 11(2017)S68】Metformin effects on clinical outcome in advanced HCCpatients receiving sorafenib: validation study

313 ラベプラゾールナトリウム【第13回日本消化管学会総会学術集会プログラム・抄録集. (2017)143】胃酸分泌抑制薬の薬物間相互作用―Clopidogrelとの相互作用を中心に―

314 ラベプラゾールナトリウム【日本静脈経腸栄養学会雑誌. 32(2017)400】プロトンポンプ阻害剤の使用に伴う下痢の発症に関する調査

315 ラベプラゾールナトリウム【第13回日本消化管学会総会学術集会プログラム・抄録集. (2017)144】プロトンポンプ阻害剤服用による胃粘膜変化の検討

316 ワルファリンカリウム【Am Heart J. 184(2017)150-155】Incidence of severe renal dysfunction amongindividuals taking warfarin and implications for non-vitamin K oral anticoagulants

317 メチルジゴキシン【第81回日本循環器学会学術集会. (2017)】PJ－259　Long－Term　Prognosis　andCause　of　Death　in　Patients　Who　Had　Implantable　Cardioverter　Defibrillatoror　Cardiac　Resynchronization　Therapy　with　Defibrillator

318 ジゴキシン【第81回日本循環器学会学術集会. (2017)】PJ－259　Long－Term　Prognosis　andCause　of　Death　in　Patients　Who　Had　Implantable　Cardioverter　Defibrillatoror　Cardiac　Resynchronization　Therapy　with　Defibrillator

319 オメプラゾール【Gastroenterology. 152(2017)821-829】Proton Pump Inhibitor and Histamine-2Receptor Antagonist Use and Iron Deficiency

320 クロピドグレル硫酸塩・アスピリン【Thromb Haemost. 109(2013)825-833】High on treatment platelet reactivity againstaspirin by non-steroidal anti-inflammatory drugs . pharmacological mechanisms andclinical relevance

321 アドレナリン【社内資料】Signal Validation and Assessment report　Epinephrine and Stresscardiomyopathy

19

322 リツキシマブ（遺伝子組換え）【ISRN Transplantation. 2013(2013)】Effects of Rituximab on the Development of Viraland Fungal Infections in Renal Transplant Recipients

323 ゾルピデム酒石酸塩【J Clin Pharmacol. 57(2017)376-381】Use of Zolpidem and Risk of AcutePyelonephritis in Women: A Population-Based Case-Control Study in Taiwan

324 ワルファリンカリウム【JAMA. 317(2017)836-846】Association of Antithrombotic Drug Use With SubduralHematoma Risk

325 ボセンタン水和物【Heart Lung Circ. 26(2016)433-441】Pilot Study of Endothelin Receptor Blockade inHeart Failure with Diastolic Dysfunction and Pulmonary Hypertension(BADDHY-Trial)

326 オクスカルバゼピン【The Cochrane database of systematic reviews. (2016)1-8】Oxcarbazepine add-onfor drug-resistant partial epilepsy

327 オクスカルバゼピン【Neurology 88(2017)1-9】Risk and association of HLA with oxcarbazepine-inducedcutaneous adverse reactions in Asians

328 クリーム【Environmental Science and Pollution Research. 23(2016)5179-5188】Effects ofrealistic concentrations of TiO2 and ZnO nanoparticles in Prochilodus lineatusjuvenile fish

329 美白化粧品（医薬部外品）【第46回日本皮膚アレルギー・接触皮膚炎学会総会学術大会. (2016)】ロドデノール誘発性脱色素斑のモデルマウスによる解析　治療の試み

330 美白化粧品（医薬部外品）【第27回日本色素細胞学会学術大会. (2016)】ロドデノールユーメラニンは強い酸化促進作用をもつ

331 美白化粧品（医薬部外品）【第27回日本色素細胞学会学術大会. (2016)】N-acetylcysteine（NAC）は紫外線によるロドデノールの色素細胞障害性増強効果を軽滅する

332 美白化粧品（医薬部外品）【第27回日本色素細胞学会学術大会. (2016)】ロドデノール誘発性脱色素斑の病態

333 美白化粧品（医薬部外品）【第27回日本色素細胞学会学術大会. (2016)】白斑におけるメラノサイト、樹状細胞動態の検討

334 美白化粧品（医薬部外品）【第27回日本色素細胞学会学術大会. (2016)】ロドデノール白斑発症機構の解析

335 美白化粧品（医薬部外品）【第27回日本色素細胞学会学術大会. (2016)】グルタチオンの維持はロドデノールに曝露されたメラノサイトの生存に重要である

336 美白化粧品（医薬部外品）【Pigment Cell and Melanoma Research. (2016)】The Potent Pro-oxidant Activity ofRhododendrol-Eumelanin Induces Cysteine Depletion in B16 Melanoma Cells

337 美白化粧品（医薬部外品）【第41回日本研究皮膚科学会学術大会. (2016)】白斑と化学物質による脱色素症の重症度評価のための新規イメージング定量法

338 美白化粧品（医薬部外品）【第41回日本研究皮膚科学会学術大会. (2016)】白斑およびロドデノール誘発脱色素斑患者の免疫学的解析

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339 美白化粧品（医薬部外品）【第41回日本研究皮膚科学会学術大会. (2016)】白斑およびロドデノール誘発脱色素斑患者の樹状細胞の動態可視化

340 美白化粧品（医薬部外品）【第41回日本研究皮膚科学会学術大会. (2016)】肥満細胞活性化がロドデノール白斑周縁部の一時的な色素産生増強を亢進させる可能性

341 クリーム【Toxicol Sci. 150(2016)454-472】Zinc-Oxide Nanoparticles ExhibitGenotoxicClastogenicCytotoxic and Actin Depolymerization Effects by InducingOxidative Stress Responses in Macrophages and Adult Mice

342 美白化粧品（医薬部外品）【Visual Dermatology. 16(2017)150-153】自己免疫疾患としての尋常性白斑

343 美白化粧品（医薬部外品）【Journal of Dermatology. (2016)1-6】Clinical and epidemiological analysis in 149cases of rhododendrol-induced leukoderma

344 美白化粧品（医薬部外品）【Journal of the Physical Society of Japan. （2017）】Density functional theory-basedfirst principles calculations of rhododendrol-quinone reactions: Preference to thiolbinding over cyclization

345 美白化粧品（医薬部外品）【日本香粧品学会誌. 40(2016)259-261】Effect of Layered Application of DifferentCosmeceutical Formulations Containing Rhododendrol

346 美白化粧品（医薬部外品）【日本皮膚科学会誌. 127(2017)137-144】新・皮膚科セミナリウム　白斑：ロドデノール誘発性脱色素斑up to date 1疫学調査その1　ロドデノール誘発性脱色素斑の臨床症状と検査結果

347 美白化粧品（医薬部外品）【日本皮膚科学会誌. 127(2017)145-153】新・皮膚科セミナリウム　白斑：ロドデノール誘発性脱色素斑up to date 2疫学調査その２　ロドデノール誘発性脱色素斑の臨床経過と治療

348 美白化粧品（医薬部外品）【日本皮膚科学会誌. 127(2017)155-160】新・皮膚科セミナリウム　白斑：ロドデノール誘発性脱色素斑up to date 3メラニン産生細胞におけるロドデノールの毒性機序

349 美白化粧品（医薬部外品）【西日本皮膚科学会誌. 79(2017)86-89】ロドデノール誘発脱色素斑に対するターゲット型エキシマライトによる紫外線治療の有用性

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【jama oncol. 3(2017)49-55】association … colitis with concomitant use of nsaids and proton pump...

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