iotaderma #226

1
IOTADERMA #226 What are caterpillar bodies and in what diseases do they occur? Robert I. Rudolph, MD, FACP Answer will appear in the JAAD Online section of the December issue of the Journal. OCTOBER IOTADERMA (#225) We dermatologists delight in arcane names, and one such term is ‘‘farcy buds.’’ What are these, and in what disease are they found? Answer: ‘‘Farcy buds’’ is one of the cutaneous manifestations of chronic glanders and consists of deep nodules, which sometimes ulcerate, and oftentimes occur in a sporotrichoid pattern on a limb. Glanders is an infection afflicting both animals and humans, and is caused by the bacillus Burkholderia mallei (formerly called Pseudomonas mallei). The clue to the diagnosis in people (along with pathology, rising antibody titers, and culture) is a history of close contact with mules or horses. Treatments of choice are the antibiotics ceftazidime, meropenem, or imipenem, although other antibiotics can be used. REFERENCES Dvorak GD, Spickler AR. Glanders. J Am Vet Med Assoc 2008;233:570-7. Estes DM, Dow SW, Schweizer HP, Torres AG. Present and future therapeutic strategies for melioidosis and glanders. Exp Rev Anti Infect Ther 2010;8:325-38. Robert I. Rudolph, MD, FACP e243

Upload: robert-i

Post on 27-Nov-2016

212 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Iotaderma #226

IOTADERMA #226

What are caterpillar bodies and in what diseases do they occur?

Robert I. Rudolph, MD, FACP

Answerwill appear in the JAADOnline section of theDecember issue of the Journal.

OCTOBER IOTADERMA (#225)

We dermatologists delight in arcane names, and one such term is ‘‘farcybuds.’’ What are these, and in what disease are they found?

Answer: ‘‘Farcy buds’’ is one of the cutaneous manifestations of chronicglanders and consists of deep nodules, which sometimes ulcerate, andoftentimes occur in a sporotrichoid pattern on a limb. Glanders is aninfection afflicting both animals and humans, and is caused by the bacillusBurkholderia mallei (formerly called Pseudomonas mallei). The clue to thediagnosis in people (along with pathology, rising antibody titers, andculture) is a history of close contact with mules or horses. Treatments ofchoice are the antibiotics ceftazidime, meropenem, or imipenem, althoughother antibiotics can be used.

REFERENCES

Dvorak GD, Spickler AR. Glanders. J Am Vet Med Assoc 2008;233:570-7.

Estes DM, Dow SW, Schweizer HP, Torres AG. Present and future therapeutic strategiesfor melioidosis and glanders. Exp Rev Anti Infect Ther 2010;8:325-38.

Robert I. Rudolph, MD, FACP

e243