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Acta Biochim Biophys Sin (Shanghai) 2011; 43:103-9.

Introduction of Management of Prostate Cancer: a

Multidisciplinary Approach

Hong-jun Li

Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical

Sciences & Peking Union Medical College, Beijing 100730, China

Management of Prostate Cancer:

a Multidisciplinary Approach published

by Springer provides an exhaustive

review of the state of the art in the

management of prostate cancer, from

screening to treatment. The authors

are all experts in their fields, and the

editors are members of the European

Organization for Research on Treatment

of Cancer (EORTC), who have coordinated phase III EORTC

trials and enjoy international reputation. A particualr feature

of the monograph is the emphasis on the value of a

multidisciplinary approach. The opening chapters address

basic aspects including epidemiology, biology, and chemopre-

vention of prostate cancer. The role of individual and mass

screening is carefully appraised, and diagnosis, clinical

work-up, and the role of active surveillance are discussed in

detail. Subsequent chapters are devot to the therapies that

may be employed. Up to date data from clinical trials are

included. In addition, the European Association of Urology

(EAU) guidelines are presented and advice is given on the

interpretation of results.

The book consists of 23 chapters, covering the

following topics: epidemiology of prostate cancer in Europe;

chemoprevention of prostate cancer; individual and mass

screening; anatomical pathology; biomarkers of prostate

cancer; diagnosis, clinical work-up, TNM classification,

markers; active surveillance for risk of prostate cancer:

background, patient selection, triggers for intervention,

and outcomes; open radical prostatectomy; robot-assisted

radical prostatectomy; permanent prostate brachytherapy;

indications, technique, and results of high-dose-rate

brachytherapy; intensity-modulated radiotherapy for

prostate cancer; combination of androgen deprivation

therapy and radiation therapy for locally advanced and

localized prostate cancer; immediate or early delayed

postoperative irradiation; high-intensity focused ultrasound

for prostate cancer; cryotherapy; follow-up after radical

treatments and relapse; first-line hormonal manipulation

of prostate cancer; resistance to chemical castration and

second-line hormonal treatment; targeted therapies and

vaccination; how to interpret results; management of

prostate cancer, EAU guidelines on screening, diagnosis,

and treatment; better patients’ perspective.