international quality assurance programme (iqap ... · syvbym amfetamin t5xitx amphetamine t9w94q...

INTERNATIONAL QUALITY ASSURANCE PROGRAMME (IQAP)

INTERNATIONAL COLLABORATIVE EXERCISE (ICE)

Summary ReportSEIZED MATERIAL

2012/1

INTERNATIONAL QUALITY ASSURANCE PROGRAMME (IQAP)INTERNATIONAL COLLABORATIVE EXERCISE (ICE)

2012/1-SM Copyright (c) 2012 UNODC(2)

Table of contents

Introduction Page 4 Comments from the International Panel of Forensic Experts Page 4 Codes and Abbreviations Page 5 Sample 1 Analysis Page 6 Identified substances Page 6 Statement of findings Page 9 Identification methods Page 17 Summary 1 Z-Scores Page 22 Sample 2 Analysis Page 24 Identified substances Page 24 Statement of findings Page 27 Identification methods Page 35 Summary Page 39 Z-Scores Page 40 Sample 3 Analysis Page 42 Identified substances Page 42 Statement of findings Page 45 Identification methods Page 53 Summary Page 57 Z-Scores Page 58 Sample 4 Analysis Page 60 Identified substances Page 60 Statement of findings Page 63 Identification methods Page 71 Summary Page 75 Z-Scores Page 76

This report contains the data received from laboratories participating in the current exercise. The results compiled in this report are not intended to be an overview of the quality of work and cannot be interpreted as such. These comments do not reflect the general state of the art within the profession.

Participant results are reported using a randomly assigned "WebCode". This code maintains participant's anonymity, provides linking of the various report sections, and will change with every report.

Samples Substances Concentrations Comments on substances

Sample 1 Caffeine quantification not required

Amfetamine 25.3 %

Lactose quantification not required

Sample 2 N-Ethyl- methylenedioxyamphetamine (MDEA) 81.0 %

Sample 3 Cocaine 86.3 %

Sample 4 Heroin 74.7 %

Test Samples Information

Samples Comments on samples

Sample 1 SM1 was prepared from a seizure containing 25.3% w/w amfetamine base. The seizure also contained caffeine and lactose.

Sample 2 SM2 was prepared from a seizure containing 81.0% w/w N-ethyl-methylenedioxyamphetamine (MDEA) base.

Sample 3 SM3 was prepared from a seizure containing 86.3% w/w cocaine base.

Sample 4 SM4 was prepared from a seizure containing 74.7% w/w heroin base.The seizure also contained acetyl codeine.





Introduction An important element of the UNODC International Quality Assurance Programme (IQAP) is the implementation of the International Collaborative Exercises (ICE). The exercises allow laboratories, from both developing and developed countries, to continuously monitor their performance in drug testing on a truly global scale. This report provides information on analytical results of laboratories participating in the Seized Materials (SM) group. In order to maintain confidentiality, the participating laboratories have been assigned random “Web Codes”, which change every round. Two rounds are offered per year with each round presenting participants with four different test samples for analysis. The analytical results returned by laboratories participating in ICE are evaluated by UNODC and a confidential report is provided to each laboratory on its own performance. Analytical results are reviewed by the UNODC’s International Panel of Forensic Experts which oversees the implementation of these exercises, and offers guidance and support in addressing relevant quality issues. The exercises provide an overview of the performance and capacity of participating laboratories and enable UNODC to tailor technical support in the laboratory sector for greatest impact.

Comments from the International Panel of Forensic Experts Participation of Laboratories Samples within both the Seized materials (SM) and Biological Specimens (BS) test groups were sent to 143 laboratories in 53 countries. Within the SM test group, samples were sent to 119 laboratories in 43 countries and 112 laboratories (94%) submitted the results of their analysis in time for inclusion in the summary report, with 109 (97%) using the ICE portal for return of results. The almost universal usage of the ICE portal is a high endorsement of its utility. Some laboratories continue to have difficulty in obtaining import authorization and this resulted in an extension of the deadline for submission of results. Qualitative Analysis The results for the qualitative identification of the controlled substances were excellent for all test samples in the SM group with correct identification by 95% (SM-1), 95% (SM-2), 100% (SM-3) and 98% (SM-4) of participants. Over 86% of participants used GC-MS indicating the availability of a high level of technical expertise amongst the majority of participants. With regard to the false positives reported for controlled substances in the SM test group, there was one within SM-1 for heroin, seven within SM-2 ( three for MDMA and one each for MBDB, morphine, caffeine and lactose ). In the SM-3 sample containing cocaine, there were two false positives for procaine and one each for ketamine, lidocaine and lactose. Within the SM-4 test sample there were two false positives for cocaine, one for MDMA and eight for morphine. Within SM-3 there were also four false positives reported for some degradation products of cocaine. In addition, there were a total of nine false negative results throughout the four test samples (three for SM-1, five for SM-2 and one for SM-4). Quantitative Analysis A modified Z-score was used for the statistical examination of the quantitative results, as it is a robust method based on absolute deviations from the median of all participant values and is relatively insensitive to outliers. The proportion of participants who carried out quantitative analysis, 63 (59%) for SM-1, 59 (55%) for SM-2, 76 (72%) for SM-3 and 72 (68%) for SM-4 continues to be encouraging. Analysis of the Z-scores showed that 49 out of 65 (75%) of participants provided acceptable quantitative results with Z-scores within 3.5 for amfetamine in SM-1, 53 out of 61 (87%) for N-ethyl-methylenedioxyamphetamine in SM-2, 72 of 78 (92%) laboratories for cocaine in SM-3 and 70 of 77 (91%) for heroin in SM-4. Participants with Z-scores outside acceptable limits should review their quantification procedures. 52% of participants carried out quantitation of all 4 samples,(an increase from 46% in the previous round) and encouragement should be given for those who do carry out quantitative analysis to do so on all samples as this allows them to get a better measure of their performance over time. It is recognized that national legislative requirements might not require quantification of a particular substance and if this is the case, participants are requested to state this in their analytical results form. Participation in the ICE programme helps to monitor the effect of corrective actions and as such, laboratories reporting false positive or false negative results should investigate the reasons for this and corrective actions should be taken in order to continuously improve performance.

Codes and Abbreviations

Tech Code Name

140 Colorimetric reactions

141 Marquis reagent (sulphuric acid, formaldehyde)

142 Cobalt thiocyanate

150 Thin Layer Chromatography

160 High Performance Liquid Chromatography

161 High Performance Liquid Chromatography with diode array detection

170 Gas Chromatography NPD

171 Gas Chromatography FID

172 Gas Chromatography ECD

180 Gas Chromatography/Mass Spectrometry

190 Fourier Transform Infrared Spectrometry

200 Spectrophotometry (visible, UV)

210 Others (specify)

211 NMR

220 Microcrystal test

230 Liquid chromatography/mass spectrometry

231 Liquid chromatography/tandem mass spectrometry

(+) “positive”: Indicates that the analyte is identified; for presumptive tests (e.g. colour reactions), indicates that a positive reaction was obtained.

(-) “negative”: Indicates that the analyte is not identified.

(ANP): Analysis not performed.



Identified substances for Test Sample 1

Code Identified Substances0Y7HBU AMPHETAMINE SULFATE

10QT0O Caffeine

1729YE Amphetamine+caffeine

287652 amfetamine sulfate

2FY222 AMPHETAMINE

33H3YU Amphetamine

3LMDMT anfetamine

3Q8YUK amphetamine

3YYONN Amphetamine

487J4C amphetamine

4EHN4X amphetamine

4OETO4 Amphetamine

56IYQB AMFETAMINE

5SAAT0 Amphetamine

5TF2N6 Amphetamine

6MX93G Amphetamine

76B6K6 Amfetamine

7GNQOF amfetamine

8LWMCT Caffeine and Diacetylmorphine

9D3999 amphetamine

9NDDDB Amfetamine sulfate

9YYQQI Amphetamine

9ZNJWK amphetamine

AMMIVW Amphetamine Type Stimulants

B9SDXL caffeine

BLGDJW AMPHETAMINE

BMV3KQ Amphetamine, Caffeine

BT5WJX Amphetamine

BYUZ0H Anfetamine

C5XU5X AMFETAMINE

CEPS1E DL AMPHETAMINE

CIGGAP Amphetamine

DIOTPE amphetamine

DY420G amphetamine

EHRGGR Amphetamine

EI7DDZ Anfetamina

EIF4MO Amfetamine

FAOZDF Amphetamine

G5IBEP Amphetamine, Caffeine, Lactose

GDHGAG amfetamine

Sample 1 Analysis



Code Identified SubstancesGUZZDS Amphetamine

GXPWHS Amfetamine

GXQAKQ amfetamine

H55Z5A amfetamine

H6WRRU amphetamine and caffeine

HRTBKL Anfetamina

I2C2BM AMPHETAMINE

IHH7HR Anphetamyne

IIC5K4 AMFETAMINE

IJKRMP amphetamine

JGFHRC Amphetamine

JLBJ8O amphetamine

JR3DGD Amphetamine

JYYTTY Amphetamine

KLKFHY Amfetamine

KVO5HO amphetamine

L74777 aphetamine sulphate

LEJ7QJ Amfetamine

MATAQL Amfetamine

MLWNWW Amphetamine

MMMPMM amfetamine

MNFL3F amphetamine

MPPEJ7 Amphetamine sulphate

MRH2G7 Amphetamine

MY0BD3 Amphetamine

N0P040 Amphetamine

N0ZSF0 Caffeine

NGF9MX amphetamine

NPNSN2 Amphetamine

NTTJYT AMFETAMINE

NYZBVC AMPHETAMINE

OJYJGP AMFETAMINE

OOOGUO Anfetamine

OOOOO1 Amfetamine

PX5TNY Amphetamine

Q3B6KA Amfetamine HCL

Q4C44J amphetamine

Q9HXQ7 amfetamine

QQH5ON amfetamine

QUCPV7 Amfetamine

RERKNB Amphetamine sulphate

RTRRR2 AMPHETAMINE

RYY1YY amphetamine

S891BK amfetamine suphate



Code Identified SubstancesSYVBYM amfetamin

T5XITX Amphetamine

T9W94Q Cafeine, Amphetamine

TELWRV AMPHETAMINE

TFPG8V AMFETAMINE

TU20KV Amphetamine

U6QDT8 Amphétamine et caféïne

UBSPCY Amphetamine

UGXJWP Amphetamine

UHUDYY Amfetamine and caffeine

VBUZYV amfetamine

VIRIMT amfetamine

VK03HM amfetamine and caffeine

VQVALL AMPHETAMINE

VVVBIB anfetamina sulfato y cafeína

WE8VVH Amphétamine sulfate

WVSKJZ AMPHETAMINE

XQZEK2 amphetamine sulphate

XV7PGB Amphetamine sulphate

XXPYXA AMFETAMINE

Y36JS6 amphetamine sulfate

YHWTR3 Amfetamine

YJXI8U Amphetamine

YOBRRG Amphetamine+caffeine

YR9KQ9 Amfetamine

ZQMXAZ Amfetamine



Code Amfetamine Caffeine Lactose

0Y7HBU + + +

10QT0O - + -

The test sample 2012/1/SM-1 was analysed by Thin Layer Chromatography Techniques (TLC) and found to contain Caffeine.

1729YE + + ANPsample 2012/1/SM1 contain amphetamine

287652 + + +

This sample contains amfetamine sulfate (25.9 % as base) cut with caffeine (12.1 %) and lactose.

2FY222 + + +

THE SAMPLE CONTAINS A MIXTURE OF AMPHETAMINE, CAFFEINE AND LACTOSE

33H3YU + + +

The sample and several reference standards were subjected to colorimetric reactions, obtaining preliminary positive result for amphetamine. With regard to instrumental analysis it was determined that the sample contains lactose, caffeine and amphetamine, the above using FTIR technique and confirmed the presence of caffeine and amphetamine by GC-MS technique. We compared the results of the sample with the information obtained from the instrumental analysis of reference standards

3LMDMT + + -

The sample also contain caffeine.

3Q8YUK + + ANP

3YYONN + + ANP

With caffeine as adulterant

487J4C + + ANP

amphetamine

4EHN4X + + +

seized material contains 25.0 % of amphetamine base

4OETO4 + + ANP

On analysis the powder was found to contain amphetamine and caffeine. Amphetamine is a controlled drug under National Drug acts. Caffeine is not a controlled drug.

56IYQB + + ANP

WHITE POWDER CONTAINING 25.1% w/w OF AMFETAMINE. THE SAMPLE WAS ALSO FOUND TO CONTAIN CAFFEINE.

5SAAT0 + + ANP

White, odourless powder, orange to brown colour change with marquis reagent. The GC-MS chromatogram revealed peaks for Amphetamine

Statement of findings for Test Sample 1




5TF2N6 + + -

The powder contained 24% AMPHETAMINE together with caffeine.AMPHETAMINE is a Class B controlled drug under the provisions of National Drug acts (as amended).

6MX93G + + -

Test sample 2012/1/SM-1 contains amphetamine and caffeine

76B6K6 + + -

7GNQOF + + ANP

The sample also contained caffeine.

8LWMCT - + ANP

Test sample 2012/1/SM-1 was found to contain Caffeine and Diacetylmorphine/Heroine

9D3999 + + +

This sample is amphetamine.

9NDDDB + + +

9YYQQI + + +

The sample contains amphetamine, caffeine and lactose.

9ZNJWK + + -

AMMIVW + ANP ANP

Colorimetric test, Thin Layer chromatography for cocaine, heroin and its derivatives. Colorimetric test (Marquis Reagent) it was found that the sample in question reacted to derived from Amphetamine Type Stimulants, while in search of TLC for heroin, cocaine and its derivatives were not detected any vestiges.

B9SDXL - + ANP

1-representative sample2-colour test as screening test3-disolving the sample in solvent and introduce it into instrumentation techniques for identification , confirmation and quantification

BLGDJW + + ANP

Sample 2012/1/SM-1, an off-white, odourless powder, was found to contain Amphetamine, a controlled substance under the National Drugs Codex.

BMV3KQ + + ANP

amphetamine type stimulants

BT5WJX + + -

The powder contained 25% AMPHETAMINE together with caffeine.AMPHETAMINE is a Class B controlled drug under the provisions of National Drug acts (as amended).




BYUZ0H + + -

We found in that sample Anfetamine in a 18,45% purity (expressed as base), and caffeine as adulterant.

C5XU5X + + ANP

FOUND AMFETAMINE WITH 20.8% w/w AND CAFFEINE.

CEPS1E + + +

WE FOUND AMPHETAMINE AND IN ADDITION CAFFEINE AND LACTOSE

CIGGAP + - ANP

Analysis of the powder revealed the presence of amphetamine

DIOTPE + + -

DY420G + + ANP

we found amphetamine in SM-1 as controlled drugs

EHRGGR + ANP ANP

The powder was analysed when it was found to contain Amphetamine.

EI7DDZ + + ANP

La muestra contiene anfetamina y cafeina

EIF4MO + + ANP

The sample containes amfetamine and caffeine

FAOZDF + + ANP

Coffeine as mastrix.

G5IBEP + + +

GDHGAG + + -

amfetamine mixture with caffeine and insoluble residuum in water and ethanol

GUZZDS + + -

GC/MS, HPLC methods were used for performed analysis

GXPWHS + + +

Sample 2012/1/SM-1 consists of white powder. Amfetamine, a prohibited substance included in the National Law for Narcotics, is found to be present in this sample.

GXQAKQ + + ANP

H55Z5A + + -

amfetamine with caffeine

H6WRRU + + ANP

color test:marquis= orange turning to brown, simon= pink to cherry-redTLC: TA and TE= amphetamine and caffeineGC : amphetamine base 12.07% and caffeine 10.55%




HRTBKL + + ANP

I2C2BM + + -

Positive presumptive colorimetric results to amphetamine confirmed by gas chromatography

IHH7HR ANP ANP ANP

unquantified

IIC5K4 + + +

/

IJKRMP + ANP ANP

The sample was found to contain amphetamine

JGFHRC + + +

1) Amphetamine in 2012/1/SM-1 sample was identified by TLC and GC/MS analysis.2) Caffeine and Lactose were identified by both TLC and GC/MS

JLBJ8O + + -

The sample contains a micture of amphetamine and caffeine

JR3DGD + ANP ANP

The sample 2012/1/SM-1 gave the positive results with Marquis test it indicate present of Amphetamine type stimulants, TLC from Rf Value of two solvent system, Rf value of the sample 2012/1/SM-1 the same as Amphetamine

JYYTTY + + +

Sample 2012/1/SM-1 contains: 28.76 % m/m amphetamine, 10.98 % m/m caffeine and 43.6 % m/m lactose.

KLKFHY + + +

2012/1/sm-1 found to contaion 3% Amfetamine

KV8NYN + + +

KVO5HO + ANP ANP

First, the sample was orange with marquis reagent.Then, we identified the retention time in the chromatogram.It was amphetamine

L74777 + + +

the sample contains aphetamine sulphate, coffeine, lactose

LEJ7QJ + + -

The sample contains amfetamine wich is listed as a controlled drug,according to National Drug acts

MATAQL + + -

Amphetamine existed in base from. Besides, Caffeine was found in the sample.

MLWNWW + + ANP




MMMPMM + + ANP

amfetamine

MNFL3F + + +

The sample was found to contain amphetamine.

MPPEJ7 + + +

amphetamine sulphate, caffeine and Lactose base amphetamine 25,8%

MRH2G7 + + ANP

One glass bottle containing 0.22 grammes of a powder containing 0.06 grammes of amphetamine

MY0BD3 + + ANP

The powder was analysed and found to contain amphetamine.

N0P040 + + -

On analysis, i found the sample '2012/1/SM-1' to contains Amphetamine and Caffeine.

N0ZSF0 ANP + ANP

caffeine detected in Sample SM1

NGF9MX + + ANP

caffeine and DPIA was also detected

NPNSN2 + + ANP

Sample 2012/1/SM-1 was found to contain controlled substance AMPHETAMINE included in Table I XXXXXX (XXXX Law on psycotropic substances).Sample 2012/1/SM-1 was also found to contain CAFFEINE (not controlled).

NTTJYT + - ANP

TWO SOLVENT SYSTEM TLC CONFIRMED THE PRESENCE OF AMFETAMINE IN THIS SAMPLE AFTER THE COLOUR TEST

NYZBVC + + ANP

WHITE POWDER CONTAINING AMPHETAMINE. ALSO DETECTED CAFFEINE

OJYJGP + + +

The sample contains AMFETAMINE (base),CAFFEIN and LACTOSE

OOOGUO + + ANP

Applied chemical tests and instrumental chemical analysis, we conclude that sample 2012/1/SM-1 contains Anfetamine.

OOOOO1 + ANP ANP

PPPGPP ANP + ANP

Sample contain caffeine

PX5TNY + + ANPSample contained 25.8% ampetamine and additionally caffeine.




Q3B6KA + + +

Amfetamine HCL is mixed with Lactose and Caffeine

Q4C44J + + +

CR, GC/FID, TLC, FTIR, also contains caffeine and lactose

Q9HXQ7 + + +

the sample contains amfetamine which is scheduled as illicit drug in this country

QQH5ON + ANP ANP

QUCPV7 + + -

In the test sample 2012/1/SM-1 were detected amfetamine and caffeine.

RERKNB + + +

SM-1 contain a mixture of Amphetamine sulphate, Coffeine and Lactose with 25% Amphetamine (as Base)

RTRRR2 + + +

AMPHETAMINE SULFATE (26% as base) - CAFFEINE - LACTOSE

RYY1YY + + ANP

caffeine, DPIA

S891BK + + +

white powder, mixture of the amfetamine, caffeine and lactose

SYVBYM + + -

T5XITX + + +

The sample SM1 contained 25,8% amphetamine calculated as a base. In the sample was identified caffeine and lactose.

T9W94Q + + ANP

TELWRV + + +

Amphetamine sulfate, caffeine and lactose

TFPG8V + + -

The result of the tests of the SM1(22) received confirms that the mentioned sample contains anfetamine with 24.5 percentage by weight (24.5%) and cafeine (as not controlled drug).

TU20KV + + -

The sample is containing 15% amphetamine with adulterant caffeine

U6QDT8 + + -

après analyse, l'échantillon 2012/1/SM-1 contient de l'amphétamine et de la caféïne

UBSPCY + + -

on analysis, i found the substance to contain 25.27% of amphetamine




UGXJWP + + ANP

Amphetamine was found with purity of 25.76%. Caffeine was also present in SM-1.

UHUDYY + + -

VBUZYV + + -

VIRIMT + + ANP

the powder SM1 contains 23.5% of amfetamine (expressed in mafetamine free base)

VK03HM + + ANP

the sample contains amfetamine and caffeine and was performed by GCMS and HPTLC

VQVALL + + ANP

THE SAMPLE CONTAINS AMPHETAMINE AND CAFFEINE

VVVBIB + + ANP

se realizó pruebas de Marquis, Scott, Simon, Lieberman´s, Espectrofotometría UV, HPLC-DAD, FT-IR

WE8VVH + + -

L'échantillon contient de l'amphétamine en mélange avec de la caféine. L'amphétamine est une substance stupéfiante reprise de l'arrêté nationale.

WVSKJZ + + -

In this sample we have detected amphetamine and caffeine.We have used colorimetric reactions (marquis reagent, cobalt thiocyanate) for screening. For identificaction/confirmation we have used GC/FID and GC/MS. For amphetamine cuantification as base we have used GC/FID. For this compound (amphetamine) the percentage by weight is 25,51 %.

XQZEK2 + + +

caffeine, lactose

XV7PGB + + ANP

The off-white powder contained an average of 34% of amphetamine sulphate and caffeine.

XXPYXA + + ANP

SAMPLE WAS DISSOLVED INTO A CERTAIN AMOUNT OF MeOH/CHCl3 SOLUTION. SOLUTION WAS ANALYZED BY GC-MS AND ITS MASS SPECTRA WAS COMPARED TO THE ONE COLLECTED ON A 1 ppm FRESH PREPARED SOLUTION OF D,L-AMFETAMINE

Y36JS6 + + +

Amphetamine is present and identified by GC-MS analysis. It was quantified by HPLC-DAD analysis upon a calibration curve performed with a certified reference material. This sample contains caffeine and lactose as adulterants.

YHWTR3 + - -

YJXI8U + + -

Caffeine




YOBRRG + + -

YR9KQ9 + + +

Lactose, identification by IRFT, Cafeine identification by GC-MS, amfetamien quantification by gravimetric method and total percentage on GC-MS trace

ZQMXAZ + + -



Identification methods for Test Sample 1

Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

0Y7HBU S S S I I

10QT0O S S I I Ehrlich Test

1729YE I S ionscan

287652 I I I I

2FY222 S I I

33H3YU S S I I

3LMDMT SI SI I

3Q8YUK S S S I

3YYONN I SI

487J4C I SI

4EHN4X I I S ion mobility spectrometry

4OETO4 I I

56IYQB I SI

5SAAT0 I SI SI I SI IR hazmat ID

5TF2N6 S S I I

6MX93G SI S S I I

76B6K6 SI S I I I I

7GNQOF SI SI

8LWMCT SI

9D3999 S I I I

9NDDDB I SI

9YYQQI S I SI SI

9ZNJWK S I I

AMMIVW S S I

B9SDXL S S SI I I I

BLGDJW S S I I

BMV3KQ I SI

BT5WJX S S I I

BYUZ0H S I I

C5XU5X SI

CEPS1E I I SI

CIGGAP SI SI I I

DIOTPE S I I

DY420G S I I

Analytical Technique Codes

Legend: S ... used for Screening I ... used for Identification SI ... used for both



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

EHRGGR S I

EI7DDZ S I

EIF4MO S I I

FAOZDF SI

G5IBEP S S S I I I I

GDHGAG S I I

GUZZDS I SI I

GXPWHS S S I I I I

GXQAKQ I SI

H55Z5A SI SI SI S I I

H6WRRU S S I I

HRTBKL SI I I SI

I2C2BM S S I I I

IHH7HR I S S I S duquenois

IIC5K4 I SI SI

IJKRMP S I SI

JGFHRC S S S I I

JLBJ8O S S S I I

JR3DGD S S S I

JYYTTY I I S

KLKFHY S S S SI I

KV8NYN SI I

KVO5HO I S S I

L74777 SI I I

LEJ7QJ I I

MATAQL S I I

MLWNWW

S S I S duquenois-levine

MMMPMM

I S SI

MNFL3F SI I HPLC/ELSD

MPPEJ7 S S S I I I I XRD

MRH2G7 S S I I SI I

MY0BD3 S S I I

N0P040 S S I I I S Dequenois-Levine Test

N0ZSF0 S S I I

NGF9MX S SI I

NPNSN2 S I S

NTTJYT S I

NYZBVC S SI I SI



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

OJYJGP S S I

OOOGUO S S S I

OOOOO1 I

PPPGPP SI UPLC-Q-TOF

PX5TNY I SI

Q3B6KA SI S S I I I S Ehrlich's Modified

Q4C44J SI S S SI I I

Q9HXQ7 S I I I

QQH5ON I SI

QUCPV7 I I

RERKNB I S I I

RTRRR2 S S S I I

RYY1YY S I S Fast Blue reagent

S891BK SI I

SYVBYM SI

T5XITX I I

T9W94Q S S I I

TELWRV SI

TFPG8V S S I I

TU20KV I S S SI I SI I

U6QDT8 S I

UBSPCY S S S I

UGXJWP S I

UHUDYY SI SI SI I

VBUZYV SI

VIRIMT S S I SI I SI

VK03HM SI I

VQVALL S I

VVVBIB S S S I I I I I

WE8VVH SI SI I

WVSKJZ S I I I

XQZEK2 S S I I XRD, ATR

XV7PGB S S I I

XXPYXA I SI

Y36JS6 I I I SI S HPLC-RI

YHWTR3 I I S FPIA

YJXI8U S I SI

YOBRRG S S S SI I I I

YR9KQ9 SI SI



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

ZQMXAZ S S S I I





Amfetamine: 106

Caffeine: 101

Lactose: 31

False positives for SM-1:

Code Name Technique8LWMCT Heroin 180

Summary for SM-1

The response summary of all 112 participating laboratories for the identification of SM-1, frequency of use of screening and identification techniques and false postitives and negatives:

False negatives for SM-1:

Frequency of use of screening and identification techniques:

Identification of SM-1:

Code: 10QT0O, 8LWMCT, B9SDXL

Section 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

Screening 39 51 40 19 0 1 2 0 33 7 0 0 0 0 10

34.8% 45.5% 35.7% 17.0% 0.0% 0.9% 1.8% 0.0% 29.5% 6.3% 0.0% 0.0% 0.0% 0.0% 8.9%

Identification 12 5 4 35 8 15 2 34 97 30 3 1 2 4 6

10.7% 4.5% 3.6% 31.3% 7.1% 13.4% 1.8% 30.4% 86.6% 26.8% 2.7% 0.9% 1.8% 3.6% 5.4%

# labs using this technique

44 52 41 42 8 15 3 34 97 32 3 1 2 4 14

39.3% 46.4% 36.6% 37.5% 7.1% 13.4% 2.7% 30.4% 86.6% 28.6% 2.7% 0.9% 1.8% 3.6% 12.5%

Response Summary Participants: 112

Z-Scores for Test Sample 1

CODEAmfetamineMAD: 1.0

Conc. * AbsDev ZScore

0Y7HBU 30.4 5.4 3.7

287652 25.9 0.9 0.6

3Q8YUK 25.6 0.6 0.4

3YYONN 25.0 0.0 0.0

487J4C 25.0 0.0 0.0

4EHN4X 25.0 0.0 0.0

4OETO4 24.0 1.0 0.7

56IYQB 25.1 0.1 0.1

5TF2N6 24.0 1.0 0.7

76B6K6 14.2 10.8 7.3

9D3999 25.7 0.7 0.5

9YYQQI 25.8 0.8 0.5

BLGDJW 12.0 13.0 8.8

BT5WJX 25.0 0.0 0.0

BYUZ0H 18.5 6.6 4.4

C5XU5X 20.8 4.2 2.8

CEPS1E 18.7 6.3 4.2

DY420G 24.7 0.3 0.2

FAOZDF 19.7 5.3 3.6

G5IBEP 25.3 0.3 0.2

GDHGAG 45.1 20.1 13.5

GUZZDS 23.3 1.7 1.1

GXQAKQ 25.8 0.8 0.5

H55Z5A 24.0 1.0 0.7

H6WRRU 12.1 12.9 8.7

I2C2BM 14.6 10.4 7.0

IIC5K4 25.4 0.4 0.3

JGFHRC 26.5 1.5 1.0

JYYTTY 28.8 3.8 2.5

KLKFHY 3.0 22.0 14.9

KV8NYN 21.9 3.1 2.1

KVO5HO 25.4 0.4 0.3

LEJ7QJ 25.0 0.0 0.0

MATAQL 14.2 10.8 7.3

MLWNWW 20.8 4.2 2.8

MMMPMM 23.0 2.0 1.4

MPPEJ7 25.8 0.8 0.5

MRH2G7 25.2 0.2 0.1

NPNSN2 16.8 8.2 5.5

PX5TNY 25.8 0.8 0.5

Q4C44J 21.0 4.0 2.7



CODEAmfetamineMAD: 1.0


Q9HXQ7 25.0 0.0 0.0

QQH5ON 37.0 12.0 8.1

QUCPV7 25.0 0.0 0.0

RERKNB 25.0 0.0 0.0

RTRRR2 26.0 1.0 0.7

S891BK 25.8 0.8 0.5

SYVBYM 23.5 1.5 1.0

T5XITX 25.8 0.8 0.5

TELWRV 25.0 0.1 0.0

TFPG8V 23.2 1.8 1.2

TU20KV 15.0 10.0 6.8

UBSPCY 25.3 0.3 0.2

UGXJWP 25.8 0.8 0.5

UHUDYY 21.4 3.6 2.5

VBUZYV 25.4 0.4 0.3

VIRIMT 23.5 1.5 1.0

WVSKJZ 25.5 0.5 0.3

XQZEK2 25.0 0.0 0.0

XV7PGB 25.0 0.0 0.0

XXPYXA 18.9 6.1 4.1

Y36JS6 23.6 1.4 0.9

YJXI8U 27.5 2.5 1.7

YR9KQ9 34.0 9.0 6.1

ZQMXAZ 22.7 2.3 1.5

*) Concentration: w/w %

Z-Score has been calculated as modified Z-Score as it is a robust method and therefore relatively insensitive to outliers.Modified Z-Score = 0.6745 * AbsDev/MADAbsDev = Absolute value of the difference between a laboratory valueand the median of all the laboratory values for the given drug;MAD = median absolute deviation about the median.Modified Z-scores with an absolute value of greater than 3.5 should be considered as potential outliers.Reference:Iglewicz, B. and Hoaglin, D. C.: 1993 How to Detect and Handle Outliers, American Society for Quality Control, Milwaukee, WI

Substance: SM-1/Amfetamine 1.00MAD =Median = 25

Round: 2012/1

Page 1 of 4

generated at: 10/4/2012 1:24:35 PM

Z-Score has been calculated as modified Z-Score as it is a robust method and therefore relatively insensitive to outliers.Modified Z-Score = 0.6745 * AbsDev/MADAbsDev = Absolute value of the difference between a laboratory value and the median of all the laboratory values for the given drug;MAD = median absolute deviation about the median.Modified Z-scores with an absolute value of greater than 3.5 should be considered as potential outliers.Reference:Iglewicz, B. and Hoaglin, D. C.: 1993 How to Detect and Handle Outliers, American Society for Quality Control, Milwaukee, WI

Z-Score Report per Sample per Substanceinclude results submitted after deadline: No

(23)


Code Identified Substances0Y7HBU MDEA

10QT0O MDEA

1729YE MDEA

287652 MDEA hydrochloride

2FY222 MDEA

33H3YU MDEA

3LMDMT MDEA

3Q8YUK MDEA

3YYONN MDEA

487J4C MDEA

4EHN4X MDEA

4OETO4 Methylenedioxyethylamphetamine (MDEA)

56IYQB MDEA

5SAAT0 MDEA

5TF2N6 MDEA

6MX93G MDEA (N-ethyl methylenedioxy-amphetamine

76B6K6 MDEA

7GNQOF MDEA

8LWMCT 3,4-Methylenedioxy-N-Methylamphetamine

9D3999 MDEA

9NDDDB MDEA

9YYQQI MDEA

9ZNJWK MDEA

AMMIVW Morphine;3,4-methylenedioxy-metamfetamine (MDMA);N-ethyl methylenedioxy-amfetamine (MDEA);N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine (MBDB)

B9SDXL nothing

BLGDJW MDEA

BMV3KQ MDEA

BT5WJX MDEA

BYUZ0H MDEA (methylenedioxyethylamphetamine)

C5XU5X MDEA

CEPS1E MDEA

CIGGAP MDEA

DIOTPE MDEA

DY420G MDEA

EHRGGR Methylenedioxyethylamphetamine (MDEA)

EI7DDZ MDEA

EIF4MO MDEA

FAOZDF MDEA

G5IBEP MDEA

GDHGAG MDEA

Sample 2 Analysis



Code Identified SubstancesGUZZDS MDEA

GXPWHS MDEA

GXQAKQ MDEA

H55Z5A MDEA

H6WRRU MDEA

HRTBKL MDEA

I2C2BM MDEA

IHH7HR MDEA

IIC5K4 MDEA

IJKRMP MDEA

JGFHRC MDEA

JLBJ8O 3,4-methylenedioxyethylamphetamine

JR3DGD N-ethyl methylenedioxy-amfetamine (MDEA)

JYYTTY MDEA

KLKFHY MDEA

KVO5HO amphetamine derivate

L74777 MDEA

LEJ7QJ MDEA

MATAQL MDEA

MLWNWW MDEA

MMMPMM MDEA

MNFL3F MDEA

MPPEJ7 MDEA hcl

MRH2G7 MDEA

MY0BD3 MDEA

N0P040 MDEA

N0ZSF0 MDEA

NGF9MX MDEA

NPNSN2 Methylenedioxyethylamphetamine

NTTJYT N-ethyl methylenedioxy-amfetamine(MDEA)

NYZBVC MDEA

OJYJGP MDEA

OOOGUO MDEA

OOOOO1 MDMA

PPPGPP MDEA

PX5TNY MDEA

Q3B6KA MDEA

Q4C44J MDEA x HCl

Q9HXQ7 MDEA

QQH5ON MDEA

QUCPV7 N-ethylmethylenedioxy-amfetamine (MDEA)

RERKNB MDEA

RTRRR2 MDEA

RYY1YY MDEA



Code Identified SubstancesS891BK MDEA hydrochloride

SYVBYM mdea

T5XITX MDEA

T9W94Q MDEA

TELWRV MDEA

TFPG8V MDEA

TU20KV MDEA

U6QDT8 MDEA

UBSPCY MDEA-N-Ethyl Methylenedioxy - Amphetamine

UGXJWP 3, 4Methylenedioxyethylamphetamine

UHUDYY MDEA

VBUZYV MDEA

VIRIMT MDEA

VK03HM MDEA

VQVALL MDEA

VVVBIB 3,4-metilendioxetileanfetamina

WE8VVH MDEA,HCl

WVSKJZ MDEA

XQZEK2 MDEA HCl

XV7PGB MDEA HCl

XXPYXA MDEA

Y36JS6 MDEA

YHWTR3 MDEA

YJXI8U MDEA

YOBRRG MDEA

YR9KQ9 MDEA

ZQMXAZ N-ethyl- methylenedioxyamphetamine (MDEA)



Code N-ethyl- methylenedioxyamphetamine (MDEA)

0Y7HBU +

10QT0O +

The test sample 2012/1/SM-2 was analysed by Colour Tests and Thin Layer Chromatography Techniques (TLC) and found to contain MDEA.

1729YE +

sample 2012/1/SM2 contain MDEA

287652 +

This sample only contains pure MDEA (methylenedioxy methamfetamine) hydrochloride (85.0 % as base).

2FY222 +

THE SAMPLE CONTAIN 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE

33H3YU +

The sample was subjected to colorimetric tests being obtained preliminary result for methamphetamine. Subsequently the sample was analyzed by FT-IR and compared with different reference standards resulting MDEA. Finally, the sample was analyzed by GC-MS confirmed that it is MDEA.

3LMDMT +

3Q8YUK +

3YYONN +

487J4C +

MDEA

4EHN4X +

seized material contains 86.6 % of MDEA base

4OETO4 +

On analysis the powder was found to contain methylenedioxyethylamphetamine (MDEA).

Methylenedioxyethylamphetamine (MDEA) is a controlled drug under National Drug acts,This is because methylenedioxyethylamphetamine is structurally derived from an N-alkyl-alpha-methylphenethylamine by substitution in the ring with an alkylenedioxy substituent.(See paragraph 1(c) of the Schedule to National Drug acts

The methylenedioxyethylamphetamine (MDEA) content of the powder was not determined.

56IYQB +

WHITE POWDER CONTAINING MDEA.





5SAAT0 +

white, odourless powder, easily soluble in water and methanol, stained with marquis reagent turned dark blue slowly turning black. GC-MS peaks for MDEA detected

5TF2N6 +

The powder contained 87% METHYLENEDIOXYETHYLAMPHETAMINE (MDEA).METHYLENEDIOXYETHYLAMPHETAMINE (MDEA) is a Class A controlled drug under the provisions of the National Drug acts.

6MX93G +

Test sample 2012/1/SM-2 contains MDEA (N-ethyl methylenedioxy-amphetamine)

76B6K6 +

7GNQOF +

8LWMCT -

Test sample 2012/1/SM-2 was found to contain 3,4-Methylenedioxy-N-Methylamphetamine

9D3999 +

This sample is MDEA.

9NDDDB +

9YYQQI +The sample is pure MDEA.HCl

9ZNJWK +

AMMIVW +

Colorimetric test, Thin Layer chromatography for cocaine, heroin and its derivatives. Colorimetric test (Nitric Acid Reagent) it was found that the sample in question reacted to amphetamines derivatives (MDMA, MDEA or MBDB) and opium Alkaloids morphina type, whereas in TLC for cocaine, heroin and its derivatives was possible verify morphina, MBDB and MDEA.

B9SDXL -

1-representative sample2-colour test as screening test3-disolving the sample in solvent and introduce it into instrumentation techniques for confirmation

BLGDJW +

Sample 2012/1/SM-2, a white, sticky, odourless powder, was found to contain MDEA, a controlled substance under the National Drugs Codex.

BMV3KQ +

amphetamine type stimulants




BT5WJX +

The powder contained 87% METHYLENEDIOXYETHYLAMPHETAMINE (MDEA).METHYLENEDIOXYETHYLAMPHETAMINE (MDEA) is a Class A controlled drug under the provisions of the National Drug acts.

BYUZ0H +

We found in that sample MDEA in a 82,71% purity (expressed as base)

C5XU5X +

FOUND MDEA WITH 81.1% w/w.

CEPS1E +

CIGGAP +

Analysis of the powder revealed the presence of MDEA

DIOTPE +

DY420G +we found N-ethyl methylenedioxyamphetamine (MDEA) in SM-2 as controlled drugs

EHRGGR +

The powder was analysed when it was found to contain Methylenedioxyethylamphetamine (MDEA).

EI7DDZ +

La muestra contiene MDEA

EIF4MO +

The sample containes N-ethyl- methylenedioxyamphetamine (MDEA)

FAOZDF +

-

G5IBEP +

GDHGAG +

GUZZDS +

GC/MS, UPLC-DAD methods were used for performed analysis

GXPWHS +

Sample 2012/1/SM-2 consists of white powder. N-ethyl-methylenedioxyamphetamine (MDEA), a prohibited substance included in the National Law for Narcotics, is found to be present in this sample.

GXQAKQ +




H55Z5A +

MDEA

H6WRRU +

color test:marquis= black, simon= deep purpleTLC: TA and TE= MDEAGC : MDEA base 82.26%

HRTBKL +

I2C2BM +

Positive presumptive colorimetric results to amphetamine derivatives and also positive to small amounts of other compounds. By gas chromatography it was demostrated the abscense of any other compound. There was a doubt between MDEA and MDE, but finally was identified MDEA through retention time and other parameters

IHH7HR ANP

unquantified

IIC5K4 +

/

IJKRMP +

The sample was found to contain MDEA

JGFHRC +

MDEA in 201/1/SM-2 sample was identified by TLC and GC/MS analysis

JLBJ8O +The sample contains MDEA

JR3DGD +

The sample 2012/1/SM-2 gave the positive results with Marquis test it indicate present of MDEA, TLC from Rf Value of two solvent system, Rf value of the sample 2012/1/SM-2 the same as MDEA

JYYTTY +

Sample 2012/1/SM-2 contains 82.98 % m/m MDEA probably as chloride.

KLKFHY +

2012/1/sm-2 found to contaion 73% MDEA

KV8NYN +

KVO5HO -

First, the sample was black wiyth marquis reagent and it was blue with simon reagent, like MDMA. We thought the sample would be MDMA. Then, the retention time was different to MDMA. Because of that, the sample is an amphetamine derivate with ring-substituted, but we do not know what it is because we do not have the pattern of this drug.

L74777 +

The saple contains MDEA




LEJ7QJ +

The sample contains MDEA wich is listed as a controlled drug,according to National Drug acts

MATAQL +

MDEA existed in base form.

MLWNWW +

MMMPMM +

MDEA

MNFL3F +

The sample was found to contain 84.3% of MDEA (as base).

MPPEJ7 +

MDEA hcl

MRH2G7 +One glass bottle containing 0.22 grammes of a powder containing 0.17 grammes of 3,4-methylenedioxyethylamphetamine, being a compound structurally derived from N-alkyl-a-methylphenethylamine by substitution in the ring with an alkyl-enedioxy substituent

MY0BD3 +

The powder was analysed and found to contain methylenedioxyethylamphetamine (MDEA).

N0P040 +On analysis, i found the sample '2012/1/SM-2' to contains MDEA.

N0ZSF0 +

MDEA detected in sample SM2

NGF9MX +

NPNSN2 +

Sample 2012/1/SM-2 was found to contain controlled substance Methylenedioxyethylamphetamine (MDEA) included in Table I of XXXXXX (XXXX Law on psycotropic substances).

NTTJYT +

tWO SOLVENT SYSTEM TLC CONFIRMED THE PRESENCE OF N-ethyl methylenedioxy-amfetamine(MDEA) IN THIS SAMPLE AFTER THE COLOUR TEST

NYZBVC +

WHITE POWDER CONTAINING MDEA.

OJYJGP +

The sample contains MDEA (chlorhydrate)




OOOGUO +

Applied chemical tests and instrumental chemical analysis, we conclude that sample 2012/1/SM-2 contains MDEA.

OOOOO1 -

PPPGPP +

Sample contain an illegal drug methylenedioxy-N-ethylamphetamine

PX5TNY +

Sample contained 59.0% MDEA

Q3B6KA +

MDEA is mixed with Lactose

Q4C44J +

CR, TLC, FTIR, GC/FID,

Q9HXQ7 + the sample contains MDEA which is scheduled as illicit drug in this country

QQH5ON +

QUCPV7 +

In the test sample 2012/1/SM-2 was detected N-ethylmethylenedioxy-amfetamine (MDEA)

RERKNB +

SM-2 contain MDEA in HCl form (83.3% MDEA Base)

RTRRR2 +

MDEA CHLORHYDRATE (84% as base)

RYY1YY +

S891BK +

white powder, only MDEA

SYVBYM +

T5XITX +

The sample SM2 contained 84,5 % MDEA calculated as a base.

T9W94Q +

TELWRV +

MDEA HCl




TFPG8V +

The result of the tests of the received SM2(42) confirms that the mentioned sample contains MDEA (3,4-methylenedioxy-N-ethylamphetamine) with 85.1 percentage by weight (85.1%) and cafeine (as not controlled drug).

TU20KV +

The sample is containing 48% MDEA

U6QDT8 +

après analyse, l'échantillon 2012/1/SM-2 ne contient du MDEA

UBSPCY +

on analysis, i found the substance to contain MDEA-N-ethylMethylenedioxy-amphetamine

UGXJWP +

3, 4-MDEA was found with purity of 94.51%.

UHUDYY -

VBUZYV +

VIRIMT +

The powder SM2 contains MDEA accordings to current protocols in the laboratory, this molecule is not quantified

VK03HM +THE SAMPLE CONTAINS MDEA AND WAS PERFORMED BY GC MS AND HPTLC

VQVALL +

THE SAMPLE CONTAINS N-ethyl- methylenedioxyamphetamine (MDEA)

VVVBIB +

se le realizó pruebas de Marquis, Scott, Simon, Cromatografía de Capa Fina, HPLC-DAD, FT-IR Y UV

WE8VVH +

L'échantillon contient majoritairement du chlorhydrate de MDEA.Le MDEA (N-ethylténamphétamine) est une substance reprise de l'arrêté nationale.

WVSKJZ +

In this sample we have detected N-ethyl- methylenedioxyamphetamine (MDEA).We have used colorimetric reactions (marquis reagent, cobalt thiocyanate) for screening. For identificaction/confirmation we have used GC/FID and GC/MS. For cuantification as base we have used GC/FID. For this compound the percentage by weight is 85,23 %.

XQZEK2 +

XV7PGB +

The white powder contained an average of >95% of methylenedioxyethylamphetamine hydrochloride (MDEA HCl)




XXPYXA +

SAME OF SAMPLE SM-1 BUT USING A 1 ppm FRESH SOLUTION OF D,L-MDEA FOR COMPARISON.

Y36JS6 +

MDEA is present and identified by GC-MS analysis. It was quantified by HPLC-DAD analysis upon a calibration curve performed with a certified reference material.

YHWTR3 +

YJXI8U +

YOBRRG +

YR9KQ9 +

identification by IRFT and GC_MS, MDEA quantification by gravimetric method and total percentage on GC-MS trace

ZQMXAZ +




Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

0Y7HBU S S S I I


1729YE I S ionscan

287652 I I I I

2FY222 S I I

33H3YU S S I I

3LMDMT SI SI I

3Q8YUK S S S I

3YYONN I SI

487J4C I SI


4OETO4 I I

56IYQB I SI


5TF2N6 S S I I

6MX93G SI S S I I

76B6K6 SI S I I I I

7GNQOF SI SI

8LWMCT SI

9D3999 S I I I

9NDDDB I SI

9YYQQI S I SI SI

9ZNJWK S I I

AMMIVW S S I

B9SDXL S S SI I I I

BLGDJW S S I I

BMV3KQ I SI

BT5WJX S S I I

BYUZ0H S I I

C5XU5X SI

CEPS1E I I SI

CIGGAP SI SI I I

DIOTPE S I I

DY420G S I I





Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

EHRGGR S I

EI7DDZ S I

EIF4MO S I I

FAOZDF SI


GDHGAG S I I

GUZZDS I SI I

GXPWHS S S I I I I

GXQAKQ I SI


H6WRRU S S I I

HRTBKL SI I I SI

I2C2BM S S I I I


IIC5K4 I SI SI

IJKRMP S I SI

JGFHRC S S S I I

JLBJ8O S S S I I

JR3DGD S S S I

JYYTTY I I S

KLKFHY S S S SI I

KV8NYN SI I

KVO5HO I S S I

L74777 SI I I

LEJ7QJ I I

MATAQL S I I

MLWNWW


MMMPMM

I S SI



MRH2G7 S S I I SI I

MY0BD3 S S I I


N0ZSF0 S S I I

NGF9MX S SI I

NPNSN2 S I S

NTTJYT S I

NYZBVC S SI I SI



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

OJYJGP S S I

OOOGUO S S S I

OOOOO1 I


PX5TNY I SI



Q9HXQ7 S I I I

QQH5ON I SI

QUCPV7 I I

RERKNB I S I I

RTRRR2 S S S I I


S891BK SI I

SYVBYM SI

T5XITX I I

T9W94Q S S I I

TELWRV SI

TFPG8V S S I I


U6QDT8 S I

UBSPCY S S S I

UGXJWP S I

UHUDYY SI SI SI I

VBUZYV SI


VK03HM SI I

VQVALL S I


WE8VVH SI SI I

WVSKJZ S I I I


XV7PGB S S I I

XXPYXA I SI


YHWTR3 I I S FPIA

YJXI8U S I SI


YR9KQ9 SI SI



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

ZQMXAZ S S S I I







Code: UHUDYY, KVO5HO, B9SDXL, 8LWMCT, 000001




Summary for SM-2

N-Ethyl-methylenedioxyamphetamine 106

Code Name Technique8LWMCT 3,4-Methylenedioxymetamfetamine (MDMA) 180

AMMIVW Morphine, MBDB 150

3,4-Methylenedioxymetamfetamine (MDMA) 150

OOOOO1 3,4-Methylenedioxymetamfetamine (MDMA) 231

Q3B6KA Lactose 140/150

TFPG8V Caffeine 180

Section 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

Screening 39 51 40 19 0 1 2 0 33 7 0 0 0 0 10

34.8% 45.5% 35.7% 17.0% 0.0% 0.9% 1.8% 0.0% 29.5% 6.3% 0.0% 0.0% 0.0% 0.0% 8.9%

Identification 12 5 4 35 8 15 2 34 97 30 3 1 2 4 6

10.7% 4.5% 3.6% 31.3% 7.1% 13.4% 1.8% 30.4% 86.6% 26.8% 2.7% 0.9% 1.8% 3.6% 5.4%


44 52 41 42 8 15 3 34 97 32 3 1 2 4 14

39.3% 46.4% 36.6% 37.5% 7.1% 13.4% 2.7% 30.4% 86.6% 28.6% 2.7% 0.9% 1.8% 3.6% 12.5%



CODE

N-ethyl- methylenedioxyamphetamine (MDEA) MAD: 2.2


0Y7HBU 71.2 12.8 3.9

287652 85.0 1.0 0.3

3Q8YUK 85.0 1.0 0.3

3YYONN 83.7 0.3 0.1

487J4C 81.0 3.0 0.9

4EHN4X 86.6 2.6 0.8

5TF2N6 87.0 3.0 0.9

76B6K6 78.4 5.6 1.7

9D3999 81.1 2.9 0.9

9YYQQI 84.5 0.5 0.2

BLGDJW 86.6 2.6 0.8

BT5WJX 87.0 3.0 0.9

BYUZ0H 82.7 1.3 0.4

C5XU5X 81.1 2.9 0.9

CEPS1E 83.7 0.3 0.1

DY420G 94.3 10.3 3.2

FAOZDF 90.1 6.1 1.9

G5IBEP 77.9 6.1 1.9

GDHGAG 85.0 1.0 0.3

GUZZDS 85.8 1.8 0.5

GXQAKQ 81.7 2.3 0.7

H55Z5A 99.0 15.0 4.6

H6WRRU 82.3 1.7 0.5

I2C2BM 95.2 11.2 3.4

IIC5K4 84.3 0.3 0.1

JGFHRC 54.3 29.7 9.1

JYYTTY 83.0 1.0 0.3

KLKFHY 73.0 11.0 3.4

KV8NYN 84.8 0.8 0.2

LEJ7QJ 80.0 4.0 1.2

MATAQL 50.3 33.7 10.3

MLWNWW 80.4 3.6 1.1

MMMPMM 82.5 1.5 0.5

MNFL3F 84.3 0.3 0.1

MRH2G7 80.3 3.7 1.1

NPNSN2 79.4 4.6 1.4

PPPGPP 47.7 36.3 11.1

PX5TNY 59.0 25.0 7.7

Q4C44J 86.0 2.0 0.6



CODE

N-ethyl- methylenedioxyamphetamine (MDEA) MAD: 2.2


Q9HXQ7 86.0 2.0 0.6

QQH5ON 55.0 29.0 8.9

QUCPV7 84.0 0.0 0.0

RERKNB 83.3 0.7 0.2

RTRRR2 84.0 0.0 0.0

S891BK 84.8 0.8 0.2

SYVBYM 82.5 1.5 0.5

T5XITX 84.5 0.5 0.2

TELWRV 83.7 0.3 0.1

TFPG8V 84.9 0.9 0.3

TU20KV 48.0 36.0 11.0

UGXJWP 94.5 10.5 3.2

UHUDYY 93.0 9.0 2.7

VBUZYV 78.9 5.1 1.6

WE8VVH 84.0 0.0 0.0

WVSKJZ 85.2 1.2 0.4

XQZEK2 85.0 1.0 0.3

XV7PGB 87.0 3.0 0.9

XXPYXA 86.1 2.1 0.6

Y36JS6 83.6 0.4 0.1

YR9KQ9 85.0 1.0 0.3

ZQMXAZ 77.1 6.9 2.1


Z-Score has been calculated as modified Z-Score as it is a robust method and therefore relatively insensitive to outliers.Modified Z-Score = 0.6745 * AbsDev/MADAbsDev = Absolute value of the difference between a laboratory valueand the median of all the laboratory values for the given drug;MAD = median absolute deviation about the median.Modified Z-scores with an absolute value of greater than 3.5 should be considered as potential outliers.Reference:Iglewicz, B. and Hoaglin, D. C.: 1993 How to Detect and Handle Outliers, American Society for Quality Control, Milwaukee, WI

Substance: SM-2/N-ethyl- methylenedioxyamphetamine (MDEA) 2.20MAD =Median = 84

Round: 2012/1

Page 2 of 4

generated at: 10/4/2012 1:24:38 PM



(41)


Code Identified Substances0Y7HBU COCAINE

10QT0O Cocaine

1729YE cocaine+anhydroecgonine methyl ester

287652 Cocaine (base)

2FY222 COCAINE

33H3YU Cocaine

3LMDMT COCAINE

3Q8YUK cocaine

3YYONN Cocaine

487J4C Cocaine

4EHN4X cocaine

4OETO4 Cocaine

56IYQB COCAINE

5SAAT0 Cocaine

5TF2N6 Cocaine

6MX93G Cocaine

76B6K6 Cocaine

7GNQOF cocaine

8LWMCT Cocaine and Ecgonidine,methyl ester

9D3999 cocaine

9NDDDB Cocaïne base

9YYQQI Cocaine

9ZNJWK cocaine

AMMIVW Cocaine; Procaine; ketamine and Lidocaine

B9SDXL cocain

BLGDJW Cocaine

BMV3KQ Cocaine

BT5WJX Cocaine

BYUZ0H Cocaine

C5XU5X COCAINE

CEPS1E COCAINE

CIGGAP Cocaine

DIOTPE cocaine

DY420G cocaine

EHRGGR Cocaine

EI7DDZ Cocaina

EIF4MO Cocaine

FAOZDF Cocaine

G5IBEP Cocaine

GDHGAG cocaine

Sample 3 Analysis



Code Identified SubstancesGUZZDS Cocaine

GXPWHS Cocaine

GXQAKQ cocaine

H55Z5A cocaine

H6WRRU cocaine

HRTBKL Cocaina

I2C2BM COCAINE

IHH7HR COCAINE

IIC5K4 COCAÏNE

IJKRMP cocaine

JGFHRC Cocaine

JLBJ8O cocaine

JR3DGD Cocaine

JYYTTY Cocaine

KLKFHY Cocaine

KVO5HO cocaine

L74777 cocaine

LEJ7QJ cocaine

MATAQL Cocaine

MLWNWW cocaine

MMMPMM cocaine

MNFL3F cocaine

MPPEJ7 Base Cocaine

MRH2G7 Cocaine

MY0BD3 Cocaine

N0P040 Cocaine

N0ZSF0 Cocaine

NGF9MX cocaine

NPNSN2 COCAINE

NTTJYT COCAINE

NYZBVC COCAINE

OJYJGP COCAINE

OOOGUO Cocaine

OOOOO1 Cocaine

PPPGPP Cocaine

PX5TNY Cocaine

Q3B6KA Cocaine

Q4C44J Cocaine

Q9HXQ7 cocaine

QQH5ON cocaine

QUCPV7 cocaine

RERKNB COCAINE

RTRRR2 COCAINE

RYY1YY cocaine



Code Identified SubstancesS891BK cocaine base

SYVBYM cocaine

T5XITX Cocaine

T9W94Q Cocaine

TELWRV Cocaine

TFPG8V COCAINE

TU20KV Cocaine

U6QDT8 Cocaïne

UBSPCY Cocaine

UGXJWP Cocaine

UHUDYY Cocaine

VBUZYV cocaine

VIRIMT Cocaïne

VK03HM COCAINE

VQVALL COCAINE

VVVBIB COCAÍNA

WE8VVH Cocaine base

WVSKJZ COCAINE

XQZEK2 cocaine base

XV7PGB cocaine

XXPYXA COCAINE

Y36JS6 Cocaine base

YHWTR3 Cocaine

YJXI8U Cocaine

YOBRRG Cocaine

YR9KQ9 cocaine

ZQMXAZ Cocaine



Code Cocaine

0Y7HBU +

10QT0O +

The test sample 2012/1/SM-3 was analysed by Colour Tests and Thin Layer Chromatography Techniques (TLC) and found to contain Cocaine.

1729YE +

sample 2012/1/SM3 contain cocaine

287652 +

This sample only contains base cocaine (94.7 %), with cocaine impurities.

2FY222 +THE SAMPLE CONTAINS A 93.3% ± 1,0% OF COCAINE

33H3YU +

The sample was subjected to colorimetric tests being obtained result for alkaloids (tanred reaction) and cocaine (scott reaction). Subsequently the sample was analyzed by FT-IR and compared with the reference standard of Cocaine. Finally, the sample was analyzed by GC-MS confirmed that it is Cocaine.

3LMDMT +

3Q8YUK +

3YYONN +

487J4C +

Cocaine

4EHN4X +

seized material contains 87.3 % of cocaine base




Code Cocaine

4OETO4 +

On analysis the powder was found to contain cocaine.

Cocaine is a controlled drug under National Drug acts.

The cocaine in this case is not exempt from control under subsection (1) of Section 3 of National Drug acts.

56IYQB +

WHITE POWDER CONTAINING 89,8% w/w OF COCAINE.

5SAAT0 +

white, odourless powder, partially soluble in methanol, turned intense blue with Scott's reagent, IR spectrometer, HAZMAT ID: Cocaine base, GC-MS peaks detected for cocaine

5TF2N6 +

The powder contained 95% COCAINE. COCAINE is a Class A controlled drug under the provisions of National Drug acts.

6MX93G +

Test sample 2012/1/SM-3 contains cocaine

76B6K6 +

7GNQOF +

8LWMCT +

Test sample 2012/1/SM-2 was found to contain Cocaine and Ecgonidine,methyl ester

9D3999 +

This sample is cocaine.

9NDDDB +

9YYQQI +

The sample is pure cocaine base.

9ZNJWK +

AMMIVW +

Colorimetric test, Thin Layer chromatography for cocaine, heroin and its derivatives. Colorimetric test (Cocaine/Crack identification Identa) it was found that the sample in question reacted to derived from cocaine, while in search of TLC for heroin, cocaine and its derivatives were identified cocaina, procaina, ketamine and lidocaine.



Code Cocaine

B9SDXL +


BLGDJW +

Sample 2012/1/SM-3, a white, sticky powder with an acrid odour, was found to contain Cocaine, a controlled substance under the National Drugs Codex.

BMV3KQ +

BT5WJX +

The powder contained 95% COCAINE. COCAINE is a Class A controlled drug under the provisions of National Drug acts.

BYUZ0H +We found in that sample Cocaine in a 91,31% purity (expressed as base)

C5XU5X +

WE FOUND COCAINE WITH 107,1+/- 8,1 % w/w UPON A CALIBRATION CURVE PERFORMED WITH UNODC STANDARD.WE FOUND COCAINE WITH 103.6 +/- 7.8 % w/w UPON A CALIBRATION CURVE PERFORMED WITH A CERTIFICATED STANDARD SOLUTION 1mg/ml).

CEPS1E +

CIGGAP +

The powder was identified as cocaine 77% purity

DIOTPE +

DY420G +

we found cocaine in SM-3 as controlled drugs

EHRGGR +

The powder was analysed when it was found to contain Cocaine.

EI7DDZ +

La muestra contiene Cocaina

EIF4MO +

The sample contains cocaine.

FAOZDF +

-



Code Cocaine

G5IBEP +

GDHGAG +

GUZZDS +

GC/MS, GC-FID methods were used for performed analysis

GXPWHS +

Sample 2012/1/SM-3 consists of white powder. Cocaine, a prohibited substance included in the National Law for Narcotics, is found to be present in this sample.

GXQAKQ +

H55Z5A +

cocaine

H6WRRU +

color test:cobalt thiocyanate = blueTLC: TA and TE= cocaineGC : cocaine base = 95.07%

HRTBKL +

I2C2BM +

Positive presumptive colorimetric results to Cocaine confirmed by gas chromatography

IHH7HR +

cocaine base

IIC5K4 +

/

IJKRMP +

The sample was found to contain cocaine.

JGFHRC +

Cocaine in 201/1/SM-3 sample was identified by TLC and GC/MS analysis

JLBJ8O +The sample contains free base cocaine, 92%

JR3DGD +

The sample 2012/1/SM-3 gave the positive results with Cobalt thiocyanate test it indicate present of Cocaine,the TLC from Rf Value of two solvent system, Rf value of the sample 2012/1/SM-3 the same as Cocaine

JYYTTY +

Sample 2012/1/SM-3 contains 90.38 % m/m cocaine as base.



Code Cocaine

KLKFHY +2012/1/sm-2 found to contaion 58% Cocaine

KV8NYN +

KVO5HO +

First, the sample was blue with Scott reagent. Then, we identified the retention time of the sample in the chromatogram. It was cocaine

L74777 +

The sample contains cocaine base.

LEJ7QJ +

The sample contains cocaine wich is listed as a controlled drug,according to National Drug acts

MATAQL +

Cocaine existed in salt form

MLWNWW +

MMMPMM +

cocaine

MNFL3F +

The sample was found to contain 88.9% of cocaine (as base).

MPPEJ7 +

base cocaine 93%

MRH2G7 +

One glass bottle containing 0.17 grammes of a solid containing 0.15 grammes of cocaine

MY0BD3 +

The powder was analysed and found to contain cocaine base.

N0P040 +

On analysis, i found the sample '2012/1/SM-3' to contains Cocaine.

N0ZSF0 +Cocaine detected in sample SM-3

NGF9MX +

NPNSN2 +

Sample 2012/1/SM-3 was found to contain controlled substance COCAINE included in Table I of XXXXXX (XXXX Law on psycotropic substances).



Code Cocaine

NTTJYT +

TLC CONFIRMED THE PRESENCE OF COCAINE IN THIS SAMPLE AFTER THE COLOUR TEST

NYZBVC +

WHITE POWDER CONTAINING COCAINE. ALSO DETECTED ECGONIDINE METHYL ESTER AND ETHYL BENZOYL ECGONINE

OJYJGP +The sample contains 93.7 % of COCAINE (base)

OOOGUO +

Applied chemical tests and instrumental chemical analysis, we conclude that sample 2012/1/SM-3 contains Cocaine.

OOOOO1 +

PPPGPP +

Sample contain controlled drug cocaine

PX5TNY +

Sample contained 82.6% cocaine

Q3B6KA +

Cocaine is mixed with Lactose

Q4C44J +

CR, TLC, FTIR, GC/FID

Q9HXQ7 +

the sample contains cocaïne which is scheduled as illicit drug in this country

QQH5ON +

QUCPV7 +

In the test sample 2012/1/SM-3 was detected cocaine

RERKNB +

SM-3 contain 89% Cocaine Base

RTRRR2 +COCAINE BASE 92%

RYY1YY +

S891BK +

white powder, cocaine base with natural impurities

SYVBYM +



Code Cocaine

T5XITX +The sample SM3 contained 96,5 % cocaine calculated as a base.

T9W94Q +

TELWRV +

COCAINE

TFPG8V +

The result of the tests of the received SM3(117) confirms that the mentioned sample contains cocaíne with 80.9 percentage by weight (80.9%).

TU20KV +

The sample is containing 89% cocaine

U6QDT8 +

l'analyse de l'échantillon 2012/1/SM-3 révèle la présence de la cocaïne

UBSPCY +

on analysis, i found the substance to contain 88.86% of cocaine

UGXJWP +

Cocaine was found with purity of 55.59%.

UHUDYY +

VBUZYV +

VIRIMT +

The powder SMQ contains cocaïne. There is not enough powder to quantify the cocaIne content

VK03HM +THE SAMPLE CONTAINS COCAINE 81% AS BASE COCAINE QUANTYFIED BY GC FID and confirmed by hptlc and gc ms

VQVALL +

THE SAMPLE CONTAINS COCAINE

VVVBIB +se le realizó marquis, scott, microcristales con HCl 0.5N /AuCl3, solubilidad y se cuantifico por HPLC-DAD, UV y se identificó con FT-IR

WE8VVH +

L'échantillon contient majoritairement de la cocaïne base.La cocaine est une substance stupéfiante reprise de l'arrêté nationale

WVSKJZ +In this sample we have detected cocaine. We have used colorimetric reactions (marquis reagent, cobalt thiocyanate) for screening. For identificaction/confirmation we have used GC/FID and GC/MS. For cuantification as base we have used GC/FID. For this compound the percentage by weight is 86,07%.



Code Cocaine

XQZEK2 +

XV7PGB +

The white powder contained an average of 88% of cocaine.

XXPYXA +

SAME OF SAMPLE SM-1 BUT USING A 1 ppm FRESH SOLUTION OF COCAINE FOR COMPARISON.

Y36JS6 +

Cocaine is present and identified by GC-MS analysis. It was quantified by GC-FID analysis upon a calibration curve performed with a certified reference material and a n-alkane as internal standard.

YHWTR3 +

YJXI8U +

YOBRRG +

YR9KQ9 +

identification by IRFT and GC_MS, Cocainequantification by gravimetric method and total percentage on GC-MS trace

ZQMXAZ +




Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

0Y7HBU S S S I I


1729YE I S ionscan

287652 I I I I

2FY222 S I I

33H3YU S S I I

3LMDMT SI SI I

3Q8YUK S S S I

3YYONN I SI

487J4C I SI


4OETO4 I I

56IYQB I SI


5TF2N6 S S I I

6MX93G SI S S I I

76B6K6 SI S I I I I

7GNQOF SI SI

8LWMCT SI

9D3999 S I I I

9NDDDB I SI

9YYQQI S I SI SI

9ZNJWK S I I

AMMIVW S S I

B9SDXL S S SI I I I

BLGDJW S S I I

BMV3KQ I SI

BT5WJX S S I I

BYUZ0H S I I

C5XU5X SI

CEPS1E I I SI

CIGGAP SI SI I I

DIOTPE S I I

DY420G S I I





Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

EHRGGR S I

EI7DDZ S I

EIF4MO S I I

FAOZDF SI


GDHGAG S I I

GUZZDS I SI I

GXPWHS S S I I I I

GXQAKQ I SI


H6WRRU S S I I

HRTBKL SI I I SI

I2C2BM S S I I I


IIC5K4 I SI SI

IJKRMP S I SI

JGFHRC S S S I I

JLBJ8O S S S I I

JR3DGD S S S I

JYYTTY I I S

KLKFHY S S S SI I

KV8NYN SI I

KVO5HO I S S I

L74777 SI I I

LEJ7QJ I I

MATAQL S I I

MLWNWW


MMMPMM

I S SI



MRH2G7 S S I I SI I

MY0BD3 S S I I


N0ZSF0 S S I I

NGF9MX S SI I

NPNSN2 S I S

NTTJYT S I

NYZBVC S SI I SI



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

OJYJGP S S I

OOOGUO S S S I

OOOOO1 I


PX5TNY I SI



Q9HXQ7 S I I I

QQH5ON I SI

QUCPV7 I I

RERKNB I S I I

RTRRR2 S S S I I


S891BK SI I

SYVBYM SI

T5XITX I I

T9W94Q S S I I

TELWRV SI

TFPG8V S S I I


U6QDT8 S I

UBSPCY S S S I

UGXJWP S I

UHUDYY SI SI SI I

VBUZYV SI


VK03HM SI I

VQVALL S I


WE8VVH SI SI I

WVSKJZ S I I I


XV7PGB S S I I

XXPYXA I SI


YHWTR3 I I S FPIA

YJXI8U S I SI


YR9KQ9 SI SI



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

ZQMXAZ S S S I I






None




Summary for SM-3

Cocaine: 112

Code Name TechniqueAMMIVW Ketamine 150

Procaine 150

Lidocaine (Lignocaine) 150

NTTJYT Procaine 150



Section 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

Screening 39 51 40 19 0 1 2 0 33 7 0 0 0 0 10

34.8% 45.5% 35.7% 17.0% 0.0% 0.9% 1.8% 0.0% 29.5% 6.3% 0.0% 0.0% 0.0% 0.0% 8.9%

Identification 12 5 4 35 8 15 2 34 97 30 3 1 2 4 6

10.7% 4.5% 3.6% 31.3% 7.1% 13.4% 1.8% 30.4% 86.6% 26.8% 2.7% 0.9% 1.8% 3.6% 5.4%


44 52 41 42 8 15 3 34 97 32 3 1 2 4 14

39.3% 46.4% 36.6% 37.5% 7.1% 13.4% 2.7% 30.4% 86.6% 28.6% 2.7% 0.9% 1.8% 3.6% 12.5%



CODECocaineMAD: 3.1


0Y7HBU 90.9 0.8 0.2

287652 94.7 4.7 1.0

2FY222 93.3 3.3 0.7

3Q8YUK 88.1 2.0 0.4

3YYONN 91.3 1.3 0.3

487J4C 89.3 0.8 0.2

4EHN4X 87.3 2.8 0.6

4OETO4 97.0 7.0 1.5

56IYQB 89.8 0.3 0.1

5TF2N6 95.0 5.0 1.1

76B6K6 97.2 7.2 1.6

9D3999 87.6 2.5 0.5

9YYQQI 89.4 0.6 0.1

B9SDXL 1.0 89.1 19.7

BLGDJW 97.8 7.8 1.7

BT5WJX 95.0 5.0 1.1

BYUZ0H 91.1 1.1 0.2

C5XU5X 103.6 13.6 3.0

CEPS1E 97.5 7.5 1.6

CIGGAP 77.0 13.1 2.9

DY420G 96.5 6.5 1.4

EHRGGR 83.0 7.1 1.6

EI7DDZ 90.5 0.4 0.1

FAOZDF 90.4 0.3 0.1

G5IBEP 92.9 2.9 0.6

GDHGAG 81.0 9.1 2.0

GUZZDS 89.3 0.8 0.2

GXQAKQ 86.8 3.3 0.7

H55Z5A 94.0 4.0 0.9

H6WRRU 95.1 5.0 1.1

I2C2BM 95.4 5.4 1.2

IHH7HR 96.7 6.7 1.5

IIC5K4 90.1 0.0 0.0

JGFHRC 85.5 4.6 1.0

JLBJ8O 92.0 2.0 0.4

JYYTTY 90.4 0.3 0.1

KLKFHY 58.0 32.1 7.1

KV8NYN 87.4 2.6 0.6

KVO5HO 92.9 2.9 0.6

LEJ7QJ 83.0 7.1 1.6

MATAQL 6.4 83.7 18.5



CODECocaineMAD: 3.1


MLWNWW 88.6 1.5 0.3

MMMPMM 87.3 2.8 0.6

MNFL3F 88.9 1.1 0.3

MPPEJ7 93.0 3.0 0.7

MRH2G7 87.1 3.0 0.7

NPNSN2 97.7 7.7 1.7

NYZBVC 92.8 2.8 0.6

OJYJGP 93.7 3.7 0.8

PPPGPP 17.1 73.0 16.1

PX5TNY 82.6 7.5 1.6

Q4C44J 92.0 2.0 0.4

Q9HXQ7 90.0 0.0 0.0

QQH5ON 74.0 16.1 3.6

QUCPV7 89.0 1.1 0.2

RERKNB 89.0 1.1 0.2

RTRRR2 92.0 2.0 0.4

S891BK 93.2 3.2 0.7

SYVBYM 97.3 7.3 1.6

T5XITX 96.2 6.2 1.4

TELWRV 94.8 4.7 1.0

TFPG8V 80.9 9.1 2.0

TU20KV 89.0 1.1 0.2

UBSPCY 88.9 1.2 0.3

UGXJWP 55.6 34.5 7.6

UHUDYY 92.7 2.7 0.6

VBUZYV 82.8 7.3 1.6

VK03HM 81.0 9.1 2.0

VVVBIB 97.5 7.5 1.6

WE8VVH 88.0 2.1 0.5

WVSKJZ 86.1 4.0 0.9

XQZEK2 92.0 2.0 0.4

XV7PGB 88.0 2.1 0.5

XXPYXA 88.2 1.8 0.4

Y36JS6 89.1 1.0 0.2

YJXI8U 93.5 3.5 0.8

YR9KQ9 89.0 1.1 0.2

ZQMXAZ 88.6 1.5 0.3


Substance: SM-3/Cocaine 3.05MAD =Median = 90.05

Round: 2012/1

Page 3 of 4

generated at: 10/4/2012 1:24:42 PM




Code Identified Substances0Y7HBU HEROINE

10QT0O Heroin

1729YE Heroine+acetylcodeine

287652 heroin hydrochloride

2FY222 HEROIN

33H3YU Heroine

3LMDMT HEROINE

3Q8YUK heroin

3YYONN Heroin

487J4C Heroine

4EHN4X heroin

4OETO4 Diamorphine

56IYQB HEROIN

5SAAT0 Heroin, 6-MAM, morphine, codeine, acetyl codeine

5TF2N6 Diamorphine

6MX93G heroine,acetyl codeine and 6 monoacetyl morphine

76B6K6 Heroine

7GNQOF heroin

8LWMCT Acetylcodein and Morphine

9D3999 heroin

9NDDDB Heroine HCl

9YYQQI Heroine

9ZNJWK heroin

AMMIVW Heroine and Cocaine

B9SDXL heroin

BLGDJW Heroin

BMV3KQ Acetylocodeine, Heroine

BT5WJX Diamorphine

BYUZ0H Heroine

C5XU5X HEROIN

CEPS1E HEROIN

CIGGAP Heroin and Morphine

DIOTPE heroine

DY420G Heroin

EHRGGR Diamorphine

EI7DDZ Heroina

EIF4MO Heroin

FAOZDF Heroine

G5IBEP Heroin,Acetylcodeine

GDHGAG heroin

Sample 4 Analysis



Code Identified SubstancesGUZZDS Heroine

GXPWHS Heroin

GXQAKQ heroin

H55Z5A heroine

H6WRRU Heroin, acetylcodeine and 6-monoacetylmorphine

HRTBKL Diacetilmorfina (heroina)

I2C2BM HEROIN

IHH7HR HEROINE

IIC5K4 HEROIN

IJKRMP heroin

JGFHRC Heroin and Morphine

JLBJ8O heroin

JR3DGD Heroin

JYYTTY Heroin

KLKFHY 6 Acetyl Morphine

KVO5HO heeroin

L74777 heroine hydrochloride

LEJ7QJ heroin

MATAQL Heroin

MLWNWW heroine

MMMPMM heroine

MNFL3F diamorphine

MPPEJ7 heroine hcl

MRH2G7 Heroin

MY0BD3 Diamorphine.

N0P040 Heroin

N0ZSF0 Heroin

NGF9MX heroine

NPNSN2 HEROIN

NTTJYT HEROIN

NYZBVC HEROIN

OJYJGP HEROIN

OOOGUO Heroin

OOOOO1 Heroin

PPPGPP Heroin

PX5TNY Heroin

Q3B6KA Heroin

Q4C44J Heroine

Q9HXQ7 heroin

QQH5ON heroin

QUCPV7 Heroin

RERKNB HEROINE

RTRRR2 HEROIN

RYY1YY heroin



Code Identified SubstancesS891BK heroin hydrochlorid

SYVBYM heroin

T5XITX Heroine

T9W94Q Heroine, 6-MAM, Acetyl Codeine, Codeine

TELWRV HEROINE

TFPG8V HEROINE

TU20KV Heroine

U6QDT8 MDMA et l'héroïne

UBSPCY Heroin

UGXJWP Heroin

UHUDYY Heroine

VBUZYV heroin

VIRIMT Heroïn

VK03HM HEROIN

VQVALL HEROIN

VVVBIB HEROÍNA Y ACETILCODEÍNA

WE8VVH Heroine ,HCl

WVSKJZ HEROIN

XQZEK2 heroin HCl

XV7PGB Diamorphine hydrochloride

XXPYXA HEROIN

Y36JS6 Heroin hydrochloride

YHWTR3 Heroin

YJXI8U Heroine

YOBRRG Heroine and 6-Acethyl Morphine and Acethyl Codeine

YR9KQ9 Heroine

ZQMXAZ Heroin



Code Heroin

0Y7HBU +

10QT0O +

The test sample 2012/1/SM-4 was analysed by Colour Tests and Thin Layer Chromatography Techniques (TLC) and found to contain Heroin.

1729YE +sample 2012/1/SM4 contain Heroine

287652 +

This sample only contains heroin hydrochloride and heroin impurities (acetylcodein and 6-monoacetyl morphine)

2FY222 +THE SAMPLE CONTAIN HEROIN

33H3YU +

The sample was subjected to colorimetric tests being obtained result for alkaloids (tanred reaction) and heroin (marquis reaction). Subsequently the sample was analyzed by FT-IR and compared with the heroine reference standard. Finally, the sample was analyzed by GC-MS confirmed that it is Heroin.

3LMDMT +The sample also contain acetil-codeine.

3Q8YUK +

3YYONN +

487J4C +

Heroine

4EHN4X +

seized material contains 81.1 % of heroin base

4OETO4 +

On analysis the powder was found to contain diamorphine.

Diamorphine is a controlled drug under National Drug acts.

56IYQB +

WHITE POWDER CONTAINING 76,5% w/w OF HEROIN

5SAAT0 +

white, odourless powder, easily soluble in water and methanol stained purple with marquis reagent, GC-MS chromatogram revealed peaks characteristic of codeine, morphine, acetylcodeine, 6-MAM and 3-MAM, diacetyl morphine




Code Heroin

5TF2N6 +

The powder contained 76% DIAMORPHINE (heroin).DIAMORPHINE (heroin) is a Class A controlled drug under the provisions of the National Drug acts.

6MX93G +

Test sample 2012/1/SM-4 contains heroine,acetyl codeine and 6 monoacetyl morphine

76B6K6 +

7GNQOF +

The sample also contained acethyl-codeine.

8LWMCT -

Test sample 2012/1/SM-4 was found to contain Acetylcodein and Morphine

9D3999 +

This sample is heroin.

9NDDDB +

9YYQQI +

The main component of the sample is heroin.

9ZNJWK +

AMMIVW +

Colorimetric test, Thin Layer chromatography for cocaine, heroin and its derivatives. Colorimetric test (Nitric Acid Reagent) it was found that the sample in question responded Alkaloids of opium to heroin type, while in search of TLC for heroin, cocaine and its derivatives were identified heroin and cocaine or its derivatives.

B9SDXL +


BLGDJW +

Sample 2012/1/SM-4, a white, sticky powder with a slightyly acidic odour, was found to contain Heroin, a controlled substance under the National Drugs Codex.

BMV3KQ +

BT5WJX +

The powder contained 83% DIAMORPHINE (heroin).DIAMORPHINE (heroin) is a Class A controlled drug under the provisions of the National Drug acts.



Code Heroin

BYUZ0H +

We found in that sample Heroin in a 80,5% purity (expressed as base).

C5XU5X +

FOUND HEROIN WITH 82.2 +/- 13.7 % w/w . IDENTIFIED ALSO 6-MONOACETYLMORFINE AND 6-ACETYLCODEINE

CEPS1E +

WE FOUND HEROIN AND IN ADDITION MONO ACETHYL MORPHINE (MAM)

CIGGAP +

The powder was identied as be illicit Heroin, 80 % purity

DIOTPE +

DY420G +

we found Diacethylmorphine (Heroin) in SM-4 as controlled drugs

EHRGGR +

The powder was analysed when it was found to contain Diamorphine.

EI7DDZ +

La muestra contiene Heroina

EIF4MO +

The sample contains heroin.

FAOZDF +-

G5IBEP +

GDHGAG +

find also 6MAM and AC

GUZZDS +

GC/MS, GC-FID methods were used for performed analysis

GXPWHS +

Sample 2012/1/SM-4 consists of white powder. Heroin, a prohibited substance included in the National Law for Narcotics, is found to be present in this sample.

GXQAKQ +

H55Z5A +

heroine with acethylcodeine and monoacethylmorphine



Code Heroin

H6WRRU +

color test:marquis= purple, mecke= deep green, Frohde = purple becoming grey/purpleTLC: TA and TE= heroinGC : heroin base 78.01% GC/MS: heroin, acetylcodeine and 6-monoacetylmorphine

HRTBKL +

I2C2BM +

Positive presumptive colorimetric results to Opiates (heroin) confirmed lately by gas chromatography

IHH7HR +

heroine base

IIC5K4 +

/

IJKRMP +

The sample was found to contain heroin

JGFHRC +

Heroin and Morphine in 201/1/SM-2 sample was identified by TLC and GC/MS analysis

JLBJ8O +

the sample contains heroine HCL, (85% reported as base)

JR3DGD +

The sample 2012/1/SM-4 gave the positive results with Marquis test it indicate present of Heroin, TLC from Rf Value of two solvent system, Rf value of the sample 2012/1/SM-4 the same as Heroin

JYYTTY +

Sample 2012/1/SM-4 contains 87.26 % m/m heroin probably as chloride.

KLKFHY +

2012/1/sm-4 found to contaion 3% Acetyl Morphine. Also Acetyl Codeine was detected.

KV8NYN +

KVO5HO +

First, the sample was purple with marquis reagent, like heroin. The sample could be heroin. Then, we identified the retention time in the chromatogram. It was heroin.

L74777 +

The sample contains heroine hydrochloride and traces of morphine.

LEJ7QJ +

The sample contains heroin wich is listed as a controlled drug,according to National Drug acts

MATAQL +

Heroin existed in salt form. We found Acetylcodeine, MAM-6 in the sample.



Code Heroin

MLWNWW +

We found heroine and also 6MAM, acetylcodeine, codeine, morphine

MMMPMM +

heroine

MNFL3F +

The sample was found to contain 78.4% of diamorphine (as base).

MPPEJ7 -

heroine hcl and acetylcodeineBase heroine 75,2%

MRH2G7 +

One glass bottle containing 0.22 grammes of a mixture containing 0.18 grammes of heroin hydrochloride, a salt of heroin

MY0BD3 +

The powder was analysed and found to contain diamorphine.

N0P040 +

On analysis, i found the sample '2012/1/SM-4' to contains Heroin.

N0ZSF0 +

Heroin detected in sample SM-4, the percentage is 75.34% and MU value is 8.28

NGF9MX +

acetil-codeine was also detected

NPNSN2 +

Sample 2012/1/SM-4 was found to contain controlled substance HEROIN included in Table I of XXXXXX (XXXX Law on psycotropic substances).Sample 2012/1/SM-4 was also found to contain Acetylcodeine.

NTTJYT +

TLC CONFIRMED THE PRESENCE OF HEROIN IN THIS SAMPLE AFTER THE COLOUR TEST

NYZBVC +

OFF-WHITE POWDER CONTAINING HEROIN. ALSO DETECTED ACETYL CODEINE AND 6-MONOACETYLMORPHINE AS BYPRODUCTS.

OJYJGP +

The sample contains 86 % of HEROIN (Chlorhydrate), ACETYLCODEIN and O6 mono ACETYLMORPHINE.

OOOGUO +

Applied chemical tests and instrumental chemical analysis, we conclude that sample 2012/1/SM-4 contains Heroin.

OOOOO1 +

PPPGPP +

Sample contain an illegal drug heroin



Code Heroin

PX5TNY +

Sample contained 81.6% heroin

Q3B6KA +

Heroin is mixed with Lactose

Q4C44J +

CR, TLC, FTIR, GC/FID, also contains Acetil Codeine and O6 Monoacetyl morphine

Q9HXQ7 +

the sample contains heroin which is scheduled as illicit drug in this country

QQH5ON +

QUCPV7 +

In the test sample 2012/1/SM-1 were detected heroin, acetylcodeine and 6-monoacetylmorphine

RERKNB +

SM-4 contain Heroine HCl form (82% Heroine Base)

RTRRR2 +

HEROIN CHLORHYDRATE (75% as base)

RYY1YY +

acetyl-codeine

S891BK +white powder, heroin and 6-monoacetylmorphine and acetylcodeine

SYVBYM +

T5XITX +

The sample SM4 contained 72,5 % heroine calculated as a base

T9W94Q +

TELWRV +

DIACETILMORPHINE AND ACETILCODEINE

TFPG8V +

The result of the tests of the received SM4(55) confirms that the mentioned sample contains heroíne with 74.5 percentage by weight (74.5%).

TU20KV +

The sample is containing 72% cocaine

U6QDT8 +

l'analyse de l'échantillon 2012/1/SM-4 révèle la présence du MDMA et de l'héroïne



Code Heroin

UBSPCY +

on analysis, i found the substance to contain 81.00% of heroin

UGXJWP +

Heroin was found with purity of 89.79%.

UHUDYY +

VBUZYV +

VIRIMT +

The powder SM4 contains 80.2 % of heroïn (expressed in heroïn free base)

VK03HM +

THE SAMPLE CONTAINS HEROIN, AND SOME METABOLITES (6-MAM and acetylcodeine)

VQVALL +

THE SAMPLE CONTAINS HEROIN

VVVBIB +

para heroína se realizaron las pruebas 140, 141, también 150, 161, 190, 200, 220

WE8VVH +

L'échantillon contient de l'héroine en mélange avec de l'acétylcodéine et de la monoacetylmorphine.

WVSKJZ +

In this sample we have detected heroin. We have used colorimetric reactions (marquis reagent, cobalt thiocyanate) for screening. For identificaction/confirmation we have used GC/FID and GC/MS. For cuantification as base we have used GC/FID. For this compound the percentage by weight is 73,46%.

XQZEK2 +

XV7PGB +The white powder contained an average of 84% of diamorphine hydrochloride.

XXPYXA +

SAME OF SAMPLE SM-1 BUT USING A 1 ppm FRESH SOLUTION OF HEROIN FOR COMPARISON.SAMPLE SM-4 WAS FOUND TO CONTAIN ALSO 6-ACETYLMORPHINE.

Y36JS6 +Heroin is present and identified by GC-MS analysis. It was quantified by GC-FID analysis upon a calibration curve performed with a certified reference material and a n-alkane as internal standard.

YHWTR3 +

YJXI8U +



Code Heroin

YOBRRG +

YR9KQ9 +

with acetylcodeine, identification by IRFT and GC_MS, quantification by gravimetric method and total percentage on GC-MS trace

ZQMXAZ +




Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

0Y7HBU S S S I I


1729YE I S ionscan

287652 I I I I

2FY222 S I I

33H3YU S S I I

3LMDMT SI SI I

3Q8YUK S S S I

3YYONN I SI

487J4C I SI


4OETO4 I I

56IYQB I SI


5TF2N6 S S I I

6MX93G SI S S I I

76B6K6 SI S I I I I

7GNQOF SI SI

8LWMCT SI

9D3999 S I I I

9NDDDB I SI

9YYQQI S I SI SI

9ZNJWK S I I

AMMIVW S S I

B9SDXL S S SI I I I

BLGDJW S S I I

BMV3KQ I SI

BT5WJX S S I I

BYUZ0H S I I

C5XU5X SI

CEPS1E I I SI

CIGGAP SI SI I I

DIOTPE S I I

DY420G S I I





Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

EHRGGR S I

EI7DDZ S I

EIF4MO S I I

FAOZDF SI


GDHGAG S I I

GUZZDS I SI I

GXPWHS S S I I I I

GXQAKQ I SI


H6WRRU S S I I

HRTBKL SI I I SI

I2C2BM S S I I I


IIC5K4 I SI SI

IJKRMP S I SI

JGFHRC S S S I I

JLBJ8O S S S I I

JR3DGD S S S I

JYYTTY I I S

KLKFHY S S S SI I

KV8NYN SI I

KVO5HO I S S I

L74777 SI I I

LEJ7QJ I I

MATAQL S I I

MLWNWW


MMMPMM

I S SI



MRH2G7 S S I I SI I

MY0BD3 S S I I


N0ZSF0 S S I I

NGF9MX S SI I

NPNSN2 S I S

NTTJYT S I

NYZBVC S SI I SI



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

OJYJGP S S I

OOOGUO S S S I

OOOOO1 I


PX5TNY I SI



Q9HXQ7 S I I I

QQH5ON I SI

QUCPV7 I I

RERKNB I S I I

RTRRR2 S S S I I


S891BK SI I

SYVBYM SI

T5XITX I I

T9W94Q S S I I

TELWRV SI

TFPG8V S S I I


U6QDT8 S I

UBSPCY S S S I

UGXJWP S I

UHUDYY SI SI SI I

VBUZYV SI


VK03HM SI I

VQVALL S I


WE8VVH SI SI I

WVSKJZ S I I I


XV7PGB S S I I

XXPYXA I SI


YHWTR3 I I S FPIA

YJXI8U S I SI


YR9KQ9 SI SI



Code 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

ZQMXAZ S S S I I



Code Name Technique5SAAT0 Morphine 180

8LWMCT Morphine 180

9D3999 Morphine 180

AMMIVW Cocaine 150

CIGGAP Morphine 171/180

JGFHRC Morphine 150/180

L74777 Morphine 150

MLWNWW Morphine 180


SYVBYM Morphine 180

U6QDT8 3,4-Methylenedioxymetamfetamine 150

VVVBIB Cocaine 161/190




Heroin: 110

Summary for SM-4The response summary of all 112 participating laboratories for the identification of SM-4, frequency of use of screening andidentification techniques and false positives and negatives:


False positives for Test Sample 4

False negatives for SM-4: Code - 8LWMCT,

Section 140 141 142 150 160 161 170 171 180 190 200 220 230 231 210

Screening 39 51 40 19 0 1 2 0 33 7 0 0 0 0 10

34.8% 45.5% 35.7% 17.0% 0.0% 0.9% 1.8% 0.0% 29.5% 6.3% 0.0% 0.0% 0.0% 0.0% 8.9%

Identification 12 5 4 35 8 15 2 34 97 30 3 1 2 4 6

10.7% 4.5% 3.6% 31.3% 7.1% 13.4% 1.8% 30.4% 86.6% 26.8% 2.7% 0.9% 1.8% 3.6% 5.4%


44 52 41 42 8 15 3 34 97 32 3 1 2 4 14

39.3% 46.4% 36.6% 37.5% 7.1% 13.4% 2.7% 30.4% 86.6% 28.6% 2.7% 0.9% 1.8% 3.6% 12.5%



CODEHeroinMAD: 3.1


0Y7HBU 78.3 2.3 0.5

287652 79.8 3.8 0.8

3Q8YUK 78.3 2.3 0.5

3YYONN 87.5 11.5 2.5

487J4C 79.1 3.1 0.7

4EHN4X 81.1 5.1 1.1

4OETO4 71.0 5.1 1.1

56IYQB 76.5 0.5 0.1

5SAAT0 58.0 18.1 3.9

5TF2N6 76.0 0.0 0.0

76B6K6 96.0 20.0 4.3

9D3999 77.5 1.5 0.3

9YYQQI 75.4 0.6 0.1

B9SDXL 0.1 75.9 16.5

BLGDJW 42.0 34.1 7.4

BT5WJX 83.0 7.0 1.5

BYUZ0H 80.5 4.5 1.0

C5XU5X 82.2 6.2 1.3

CEPS1E 75.0 1.1 0.2

DY420G 87.6 11.5 2.5

FAOZDF 83.6 7.6 1.6

G5IBEP 76.1 0.0 0.0

GDHGAG 75.6 0.5 0.1

GUZZDS 74.0 2.1 0.4

GXQAKQ 74.5 1.6 0.3

H55Z5A 78.0 2.0 0.4

H6WRRU 78.0 2.0 0.4

I2C2BM 80.4 4.3 0.9

IHH7HR 64.5 11.6 2.5

IIC5K4 75.2 0.8 0.2

IJKRMP 74.6 1.5 0.3

JGFHRC 75.6 0.5 0.1

JLBJ8O 85.0 9.0 1.9

JYYTTY 87.3 11.2 2.4

KLKFHY 3.0 73.1 15.9

KV8NYN 76.2 0.2 0.0

KVO5HO 66.0 10.1 2.2

LEJ7QJ 75.0 1.1 0.2

MATAQL 64.9 11.2 2.4

MLWNWW 85.9 9.9 2.1

MMMPMM 76.0 0.0 0.0



CODEHeroinMAD: 3.1


MNFL3F 78.4 2.4 0.5

MPPEJ7 75.2 0.8 0.2

MRH2G7 76.3 0.3 0.1

N0ZSF0 75.3 0.7 0.2

NPNSN2 67.2 8.8 1.9

NYZBVC 77.8 1.8 0.4

OJYJGP 74.0 2.1 0.4

PPPGPP 22.7 53.4 11.6

PX5TNY 81.6 5.6 1.2

Q4C44J 65.0 11.1 2.4

Q9HXQ7 73.0 3.1 0.7

QQH5ON 70.0 6.1 1.3

QUCPV7 72.0 4.1 0.9

RERKNB 82.0 6.0 1.3

RTRRR2 75.0 1.1 0.2

S891BK 75.0 1.1 0.2

SYVBYM 99.2 23.2 5.0

T5XITX 72.9 3.1 0.7

TELWRV 78.5 2.5 0.5

TFPG8V 72.3 3.8 0.8

TU20KV 72.0 4.1 0.9

UBSPCY 81.0 5.0 1.1

UGXJWP 89.8 13.7 3.0

UHUDYY 73.4 2.6 0.6

VBUZYV 78.0 2.0 0.4

VIRIMT 80.2 4.2 0.9

VVVBIB 92.1 16.0 3.5

WE8VVH 75.0 1.1 0.2

WVSKJZ 73.5 2.6 0.6

XQZEK2 75.0 1.1 0.2

XV7PGB 73.0 3.1 0.7

XXPYXA 70.4 5.6 1.2

Y36JS6 79.4 3.4 0.7

YJXI8U 77.0 1.0 0.2

YR9KQ9 86.0 10.0 2.2

ZQMXAZ 76.4 0.3 0.1


Substance: SM-4/Heroin 3.10MAD =Median = 76.05

Round: 2012/1

Page 4 of 4

generated at: 10/4/2012 1:24:44 PM



(77)

The Laboratory and Scientific SectionUNODC, International CentreWagramer Strasse 5, P.O. Box 500A-1400, Vienna, AUSTRIAEmail: [email protected]



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