International Conference on Host-Pathogen Interactions (ICHPI)

Organized by

An Autonomous Institute of Department of Biotechnology,Ministry of Science and Technology,

Government of India

July 12-15, 2014

Venue: Auditorium, School of Life Sciences, South Campus, University of Hyderabad, Hyderabad, India

Conference Program

July 12, 2014 (Saturday)

3:30 PM - 4:30 PM : Conference registrations & Hi Tea

4:30 PM - 6:30 PM : ICHPI Inauguration Ceremony

Guests of Honor

Dr. Purvi Mehta, Head-Asia, International Livestock Research Institute

Dr. T S Rao, Scientist H, Department of Biotechnology, Government of India

Inaugural Address:

Dr. Lalji Singh, Vice-Chancellor, Banaras Hindu University

Keynote Address:

Prof. Lothar Weiler, Managing Director, Institute of Microbiology and Epizootics, Freie University, Germany

on ‘Phylogenetic Molecular Typing: basis and framework to understand host-pathogen interactions’

Inauguration Dinner

July 13, 2014 (Sunday)Session on Host-Pathogen Interactions

& Poster Session I

Sessions Time Speakers TitleChairperson : Prof. Channa Reddy, Distinguished Professor Emeritus, The Pennsylvania State UniversityVenue: AuditoriumKey note presentation

9:00 AM to 9:30 AM

David HumeUniversity of Edinburgh, UK

Functional Genomics of Macrophages (002)

Presentations by invited speakers

9:30 AM to 9:50 AM

Carmen Molina Paris University of Leeds, UK

IL-7 in T cell homeostasis: modelling at the molecular, cellular and population levels (003)

9:50 AM to 10:10 AM

Suresh Kuchipudi University of Nottingham, UK

Role of skeletal muscle in avian influenza virus pathogenesis and spread (004)

10:10AM to 10:30 AM

Gordon Langsley Universite Paris Descartes, France

Autocrine and chemokine loops combine to super-activate PI3K to virulence levels promoting Theileria-transformed macrophage hyper-invasiveness (010)

Oral Presentations

10:30 AM to 10:40 AM

A S YadavCentral Avian Research Institute, India

Study of gene expression analysis of thermo-tolerant genes in Salmonella typhimurium and Salmonella enteritidis (ICHPI_OP001)

10:40 AM to 10:50 AM

Bhalchandra MirlekarNational Centre for Cell Science, India

Nuclear Matrix Protein Smar1 Control Regulatory T cell fate during Inflammatory Bowel Disease (ICHPI_OP002)

10:50 AM to 11:00 AM

Mrinal SamantaCentral Institute of Freshwater Aquaculture, India

Toll-Like Receptors Signaling In Fish: Essential role in Host- Pathogen Interaction and Immunity (ICHPI_OP003)

July 13, 2014

Sessions Time Speakers Title 11:00 am to 1:00 pm Tea and Poster Session I ICHPI_PP001 to ICHPI_PP056

1:00 PM to 2:00 PM Lunch

Sessions Time Speakers TitleChairperson : Prof. David Hume, Director, Roslin Institute, University of Edinburgh, UKVenue: AuditoriumPresentations by invited speakers

2:00 PM to 2:20 PM

Suman Kumar Dhar Jawaharlal Nehru University, India

Unique features of DNA replication and cell cycle regulation in human malaria parasite Plasmodium falciparum (011)

2:20 PM to 2:40 PM

Mrinal Kanti BhattacharyyaUniversity of Hyderabad, India

Targeting DNA double strand break repair pathways of malaria parasites (012)

2:40 PM to 3:00 PM

Elankumaran Subbiah Virginia Polytechnic Institute and State University, USA

Virulence Determinants of Influenza A virus (013)

3:00 PM to 3:20 PM

Geraldine TaylorPirbright Institute, UK

Role of the SH protein in the pathogenesis of bovine respiratory syncytial virus (014)

3:20 PM to 3:40 PM

Girish Kirimanjeswara The Penn State University, USA

Implications of Route of Infection in Tularemia Pathogenesis (015)

July 13, 2014

Sessions Time Speakers TitleBrain Storming Session

- by invitation only

2:00 PM to 3:30 PM

Recent FMD Outbreaks and Challenges to control FMD in India

Chair: KML Pathak, ICAR, India

Coordinator: Satya Parida, Visiting Faculty, NIAB, India

Venue: Seminar Hall

3:40 PM to 4:00 PM Tea Break

Brain Storming Session

4:00 PM to 5:30 PM

Onehealth / Ecohealth: Concepts, Implications and Applications

Chair: Dr. Purvi Mehta, Head-Asia, International Livestock Research InstitutePanel Members: Dr. Dan Schar, Regional Emerging Infectious Diseases Advisor USAID-Thailand, Dr. Gaya Prasad, ADG, Indian Council for Agriculture Sciences, Dr. Manish Kakkar, Public Health Foundation of India, Dr. Girish Sohni, President- BAIF, Dr. Ramadevi, BHUVenue: Auditorium

Chairperson : Prof. Geeta K Vemuganti, Dean, School of Medical Sciences, University of HyderabadVenue: AuditoriumPresentations by invited speakers

5:30 PM to 5:50 PM

R.N.K. BamezaiJawaharlal Nehru University, India

Genomic Heterogeneity and Host Response - Leprosy as a Model (005)

5:50 PM to 6:10 PM

Satya DandekarUC Davis, USA

HIV Pathogenesis: Gut immune interactions with the virus and microbiota (008)

July 13, 2014

Sessions Time Speakers Title6:10 PM to

6:30 PMSunit SinghBanaras Hindu University, India

HIV- Tat Protein Harnesses MicroRNAs to compromise the Integrity of Human Brain Microvascular Endothelial Cells (016)

Oral Presentations

6:30 PM to6:40 PM

Santosh HaunshiDirectorate of Poultry Research, India

Role of PRR pathway genes in genetic resistance to Marek’s Disease in chicken (ICHPI_OP004)

Sessions Time Speakers TitleChairperson : Dr. Nagendra Hegde, Associate Director, Ella FoundationVenue: Seminar HallPresentations by invited speakers

5:30 PM to 5:50 PM

Bernd LepeniesMax Planck Institute of Colloids and Interfaces, Germany

The role of C-type lectin receptors in pathogen recognition – from glycan arrays to murine studies (006)

5:50 PM to 6:10 PM

Sandeep PrabhuThe Penn State University, USA

The role of macrophage selenoproteins in host-pathogen interaction (009)

6:10 PM to 6:30 PM

Niyaz AhmedUniversity of Hyderabad, India

Interaction of chronic pathogen with host immune system (007)

Oral Presentation

6:30 PM to6:40 PM

Madhusudan HosamaniIndian Veterinary Research Institute (IVRI), Bangalore, India

Optimized expression of processed capsid proteins of FMD virus to enhance the yields of Virus Like Particles (VLPs) using Baculovirus System (ICHPI_OP005)

July 13, 2014

July 14, 2014 (Monday)Session on Translational Research

& Poster Session IISessions Time Speakers Title

Chairperson : Dr. V. A. Srinivasan, Advisor, National Dairy Development BoardVenue: AuditoriumKey note presentation

9:00 AM to 9:30 AM

Rakesh Bhatnagar Jawaharlal Nehru University, India

Recombinant vaccine against anthrax: From Clone to clinical trials (017)

Presentations by invited speakers

9:30 AM to 9:50 AM

Dhinakar RajTranslational Research Platform for Veterinary Biologicals, India

The Sojourn from the Investigator to the Investor – the limited experience of the Translational Research Platform for Veterinary Biologicals (018)

9:50 AM to10:10 AM

Sriranganathan NCenter for Molecular Medicine & Infectious Diseases, USA

Development and Preliminary Evaluation of a Modified-Live Immunocontraceptive Brucellosis Vaccine (019)

10:10 AM to 10:30 AM

Srinivas RaoNational Institute of Health, USA

Translation of Novel Vaccine Platforms to Veterinary Vaccinology (020)

10:30 AM to 10:40 AM

Elisabeth M. OttoFreie University, Germany

Brief Presentation on The Berlin-Hyderabad Research Training Group on Infectious Diseases and Genetic Functional Epidemiology (BRIDGE) (021)

Oral Presentations

10:40 AM to 10:50 AM

Sagar A. KhulapeIVRI, Izatnagar, India

Evaluation of Fusion gene based DNA Prime-Protein boost vaccinations against Newcastle Disease Virus ((ICHPI_OP006)

July 14, 2014

Sessions Time Speakers Title10:50 AM to

11:00 AMShukra Madhaha Indian Immunologicals Limited, India

Antibody fragment against Glycoprotein of Rabies challenge virus strain (ICHPI_OP007)

11:00 AM to 11:20 AM Tea Break

Sessions Time Speakers TitleChairperson : Dr. R. N. Chatterjee, Director, DPR, Hyderabad

Venue: AuditoriumPresentations by invited speakers

11:20 AM to 11:40 AM

Bhaskar SharmaIVRI, Izatnagar, India

Broad range detection of viruses: Methods, validation and issues (022)

11:40 AM to 12:00 PM

Keun Seuk SeoMississippi State University, USA

Inflammatory and immunoregulatory roles of microbial superantigens in bovine mastitis (027)

12:00 PM to 12:20 PM

Mana Mahapatra The Pirbright Institute UK

New insights into Foot-and-Mouth Disease virus epitopes (029)

Oral Presentations

12:20 PM to 12:30 PM

Borse Tushar Vidya Pratishthan’s School of Biotechnology, India

Protein profiling of Tick (Boophilus microplus) salivary glands as a potential candidate for vaccine development (ICHPI_OP008)

12:30 PM to 12:40 PM

Krishna JyothiVeterinary Biologicals Research Institute, India

Control of PPR by Vaccination in Andhra Pradesh state of India (ICHPI_OP009)

12:40 PM to 12:50 PM

Nigel TempertonUniversity of Kent, UK

Multiplex evaluation of Influenza neutralizing antibodies with potential applicability to in-field serological studies (ICHPI_OP010)

July 14, 2014

Sessions Time Speakers Title12:50 PM to

1:00 PMSimon ScottUniversity of Kent, UK

Use of pseudotyped viruses for investigations into vaccine efficacy, antigenic drift and vaccine breakdown for Equine Influenza (ICHPI_OP011)

Sessions Time Speakers TitleChairperson: Dr. H. Rahman, Director, National Institute of Veterinary Epidemiology & Disease Informatics (NIVEDI)Venue: Seminar HallPresentations by invited speakers

11:20 AM to 11:40 AM

Utpal TatuIndian Institute of Sciences, India

Diagnosis and treatment of animal trypanosomosis (025)

11:40 AM to 12:00 PM

Srikanta GhoshIVRI, Izatnagar, India

Progress in Development of cross-protective tick vaccine - Indian perspectives (026)

12:00 PM to 12:20 PM

Madhan MohanIVRI, Izatnagar, India

Generation of recombinant Newcastle disease virus strain R2B by reverse genetics (023)

12:20 PM to 12:40 PM

Kumanan Kathiperumal Tamil Nadu Veterinary and Animal Sciences University, India

Pathotyping and genotyping of Indian isolates of Newcastle disease virus-Do we have definite conclusion? (028)

12:40 PM to 1:00 PM

Sohini DeyIVRI, Izatnagar, India

Virus like particles: a promising vaccine platform for poultry viral diseases (024)

1:00 PM - 2:00 PM Lunch

2:00 PM to 4:00 PM Poster Session II; ICHPI_PP057 to ICHPI_PP112

July 14, 2014

Sessions Time Speakers TitleBrain Storming Session

Venue: Auditorium

4:00 PM to 5:30 PM

Antimicrobial Resistance

Chair: Dr. Gowrishankar, CDFD, India

Panel Members:

Dr. S S Sinha, DBT;

Dr. Rajesh Kapur, DBT;

Prof Weiler, Freie University, Germany;

Dr. Satya Dandekar, UC Davis, USA;

Prof Gagandeep Kang, Christian Medical College;

Dr. J P S Gill, GADVASU;

Dr. D.V. Singh, ILS Bhuvaneswar;

Dr. Radha Rangarajan, Vitas pharma;

Dr. Ashima Bhardwaj, IIAR;

Dr. Kamini Walia, ICMR

July 14, 2014

Sessions Time Speakers TitleChairperson : Prof.Sudhakar Reddy Keshireddy, Associate Dean College of Veterinary Science , Sri Venkateswara Veterinary University , RajendranagarVenue: AuditoriumPresentations by invited speakers

5:30 PM to 5:50 PM

Bindu NanduriMississippi State University, USA

Developing Host-Pathogen Interaction resources for agricultural species (031)

5:50 PM to 6:10 PM

Jagadeesh BayryINSERM, France

Targeting regulatory T cells in vaccination (032)

Oral Presentations

6:10 PM to 6:20 PM

Kalle M. ArunasreeUniversity of Hyderabad, India

Identification and characterization of mecC positive Staphylococcus aureus in clinical isolates of human and bubaline mastitis samples in India (ICHPI_OP012)

6:20 PM to 6:30 PM

Cristopher Segovia, University Mayor, Chile

Inflammatory effects of Edwardsiella ictaluri lipopolysaccharide modifications in catfish gut (ICHPI_OP013)

July 14, 2014

July 15, 2014 (Tuesday)Session on Infection and Immunity

Sessions Time Speakers TitleChairperson : Prof. Dayananda S, Dept. of Animal Sciences, University of HyderabadVenue: AuditoriumKey note presentations

9:00 AM to 9:30 AM

Dwight D. Bowman Cornell University, USA

The zoonotic potential of the parasitic protozoa and helminths of ruminants and means of control and prevention (033)

Presentations by invited speakers

9:30 AM to 9:50 AM

Hartmut Kühn Charité - Universitätsmedizin Berlin, Germany

Eicosanoid signalling in host-pathogen interactions (035)

9:50 AM to 10:10 AM

Arun Kumar Kota University of Hyderabad, India

Genetic evidence for the role of Plasmodium berghei Ubc13 kinase as a malaria transmission blocking candidate (034)

10:10 AM to 10:30 AM

Benedikt KauferInstitut für Virologie, Berlin, Germany

Marek’s disease virus (MDV) with mutations in the template region of vTR is avirulent and protects chickens from lethal challenge infection (036)

10:30 AM to 11:00 AM Tea Break

July 15, 2014

Sessions Time Speakers TitleChairperson : Prof. Manjula Sritharan, Dept. of Animal Sciences, University of HyderabadVenue: AuditoriumPresentations by invited speakers

11:00 AM to 11:20 AM

Satya ParidaThe Pirbright Institute, UK

Emergence of PPRV and Molecular evolution (037)

11:20 AM to 11:40 AM

Nanda NanthakumarVirginia Polytechnic Institute and State University, USA

Novel mouse models to elucidate the role of gut microbiome and the mechanism of enteric pathogenic infection and pathogen-induced inflammatory response (038)

Oral Presentations

11:40 AM to 11:50 AM

Megha Kadam BedekarCentral Institute of Fisheries Education, India

Co-Expression of GAPDH gene of Edwardsiella tarda and IFN-γ gene of Labeo rohita in eukaryotic cell line (ICHPI_OP014)

11:50 AM to 12:00 Noon

Shailendra Kumar VermaDefence Research & Development Establishment, India

HSP70 of Mycobacterium tuberculosis modulates immune response and protective potential of F1 and LCRV antigens of Yersinia pestis in mouse model (ICHPI_OP015)

12:00 Noon to 12:10 PM

Sabina FatimaDr. NTR University, India

Dynamics and control of Biofilms (ICHPI_OP016)

12:10 PM to 12:20 PM

Elaine YuCornell University, USA

Vitamin D: from Animals to Humans(ICHPI_OP017)

12:20 PM - 1:30 PM Lunch

July 15, 2014

Sessions Time Speakers TitlePanel Discussion

Venue: Auditorium

1:30 PM to 2:30 PM

Bio-safety and Bio-risk Management (039-041)

Chair: Dr. Lalji Singh, Banaras Hindu University

Panel members:

Dr. Cecelia Williams, Sandia National Laboratories, USA,

Dr. B. M. Gandhi, CEO, NeoBioMed Services, Former Advisor to DBT

Dr. Gopal Pande, CCMB, India,

Dr. Raju Kumar, HSADL, India

Dr. P. S. Raju, Officer-in-charge, Business Development & IP Coordination, CCMB, India

3:00 PM to 4:00 PM VALEDICTORY FUNCTION & PRIZE DISTRIBUTIONS

Distribution of Awards: Dr. Lalji Singh, VC, Banaras Hindu University

Valedictory address: Prof. Ramakrishna Ramaswamy, VC, University of Hyderabad

July 15, 2014