innovation: managing risk, not avoiding it

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Innovation: managing risk, not avoiding it

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Innovation: managing risk, not avoiding it

• Innovation is essential, but always carries risk

• Framing risk rigorously makes decisions more robust

• Context matters: science is not the only lens

• Shaping regulation and decision-making: it can be done!

2 Innovation: managing risk, not avoiding it

Innovation – managing the risks

• Increases in life expectancy (and reductions in infant mortality)

• Global gdp increases

3 Innovation: managing risk, not avoiding it

Innovation is essential to growth and wellbeing

• Cars and trains

• Contraception

Combined oral contraceptive pill - first used in USA in 1960. Currently used by over 100 million women worldwide

Has been called “greatest scientific invention,” of 20th century by some commentators

Impacts for women include: choice as to whether to have children, further education and a career

Societies respond by a mix of changing behaviours, regulation and legislation

4 Innovation: managing risk, not avoiding it

Innovation has always been contested

• Population growth (and restructuring)

• Climate risks

• Socio-economic trends

5 Innovation: managing risk, not avoiding it

21st Century context is different

• Big data

• Satellites

• Robotics and autonomous systems

• Synthetic biology

• Regenerative medicine

• Agri-science

• Advanced materials

• Energy storage

• Quantum

• Internet of things

6 Innovation: managing risk, not avoiding it

Future growth, security and wellbeing depends on effective exploitation of emerging

technologies

• Innovation is essential, but always carries risk

• Framing risk rigorously makes decisions more robust

• Context matters: science is not the only lens

• Shaping regulation and decision-making: it can be done!

7 Innovation: managing risk, not avoiding it

Framing risk

Review the evidence…….

…and acknowledge that all evidence is

•Contingent

•Uncertain

Remember that the numbers you choose are not neutral

8 Innovation: managing risk, not avoiding it

Apply the “science” of risk and risk communication

We place trust for specific purposes.

We expected the trustworthy institution or individual to

Critical Trust is especially important if cause and effect are difficult for the layperson to determine.

•Invisible, pervasive

•Long term

•Highly technical

• Take account of our interests

• Be competent

• Not be self-serving

9 Innovation: managing risk, not avoiding it

Placing trust

The system

• Systematic and cross-Departmental

• Rapid response

• Independent verification

• Credibility

Recent emergencies

• Ebola

• Flooding

10 Innovation: managing risk, not avoiding it

UK has a systematic approach to managing top national risks

• Innovation is essential, but always carries risk

• Framing risk rigorously makes decisions more robust

• Context matters: science is not the only lens

• Shaping regulation and decision-making: it can be done!

Context matters

11 Innovation: managing risk, not avoiding it

If you can’t stand the heat get out of the kitchen

•Hazards: bleach

•Exposure: bleach in the stew

•Risk = hazard x exposure: poisoning

•Vulnerability: children have greater sensitivity and greater likelihood of exposure.

•Uncertainty = degree of confidence in hazard, exposure and vulnerability

Terminology: Risk is not the same as hazard

12 Innovation: managing risk, not avoiding it

Individual responses to risk are shaped by:

•“Availability” draws on the analytical and emotional systems in the brain

•Often based on rules of thumb, reinforced by personal experience and personal networks

•With a tendency to:

– Fear a loss more than a foregone gain

– Overestimate frequency of events that can easily be recalled

We know a lot about how individuals assess cost and benefit

13 Innovation: managing risk, not avoiding it

Anticipating types of innovation

14 Innovation: managing risk, not avoiding it

Five Broad Categories Examples Responses

1. Who pays? Some medical drugs NICE

2. My pain, your gain Nuclear waste Public engagementDecisions at multiple levels

3. Science meets values Early GM, geo-engineering

Strengthen science base.Public engagement. Don’t confuse science with values.

4. Unanticipated consequences

Internet Monitor, debate, trial and learn

5. New challenges Some nanotechnologies

Monitor, adapt, regulate

Science is not the only lens

Can view “fracking” in terms of:-

•Suite of technical risks e.g. seismological or well engineering (“hydraulic fracturing”)

• Impact on local amenity (“not in my backyard”)

• Impact on global energy and carbon policy (“growth” and “greenhouses gases”)

15 Innovation: managing risk, not avoiding it

Credit: greensefa/CC BY 2.0

Credit: Al Granberg

Cultural factors - precautionary by default?

Leading to large variations in approaches to innovation and risk and on different issues in different countries

National identity and values

•Stem cells•Nuclear power•GM•Handguns

16 Innovation: managing risk, not avoiding it

GM crops: practical working guidelines

Be specific•What gene?•In what organism?•For what purpose?

17 Innovation: managing risk, not avoiding it

Have a broad view•Consider inaction as well as action•Look at multiple pathways •Science is essential, but not the only lens

• Innovation is essential, but always carries risk

• Framing risk rigorously makes decisions more robust

• Context matters: science is not the only lens

• Shaping regulation and decision-making: it can be done!

Shaping regulation

18 Innovation: managing risk, not avoiding it

Challenges

•Systemic pressures

– Economic regulators (and price)

•Asymmetric incentives

– Neonicotinoids (unintended consequences)

•Lack of proportion

– Pig inspection (what you can’t see for looking)

Challenges for regulation

19 Innovation: managing risk, not avoiding it

More challenges and opportunities in the future

20 Innovation: managing risk, not avoiding it

Challenges

•Future regulation will need to become far more agile and responsive.

•Technological change and the guardianship and use of information present key challenges

•The governance placed on regulators themselves will need to address asymmetric incentives to action and encourage more collaborative, transparent approaches.

HFEA and mitochondria replacement therapy

HFEA: Extended consultation

Multiple strategies

Outcome: Shift in public and expert opinion

Advised Secretary of State: clear public support for clinical use of mitochondria replacement treatment.

It can be done!

21 Innovation: managing risk, not avoiding it

UK has strong institutions to supply evidence and advise on risk

•Government “science advisory ecosystems”

•NICE

•What Works Centres

•National Academies

•Scientific Advisory Group in Emergencies

•Academic centres of excellence and leading practitioners

Well informed debate requires sustained capability

Strong institutions able to carry out meta-analysis and look across disciplines, working over months and years

BUT the risk community is small and fragmented.

Ad hoc studies as required

Trusted relationships, very rapid responses

22 Innovation: managing risk, not avoiding it

Call to action

Key areas where we can build on existing approaches:-

• Investment: Aligning national priorities for investment on resilience, infrastructure and innovation with an evidence and risk-based approach;

• UK coordination: Ensuring a more coherent and structured approach to assessing impact of risk in policy, regulation and crisis management;

• Regulators: Putting in place the right governance structures and incentives in relation to our regulators and regulated industries;

• Science-based EU: Rooting the approach to policy and decision-making in EU in robust scientific evidence.

23 Innovation: managing risk, not avoiding it

Every effort has been made to trace copyright holders and to obtain their permission for the use of copyright material. We apologise for any errors or omissions in the included attributions and would be grateful if notified of any corrections that should be incorporated in future versions of this slide set. We can be contacted through [email protected] .

@uksciencechief

www.gov.uk/go-science