india's universal immunisation programme to prevent children from preventable disease:...

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Meeting Abstracts www.thelancet.com 151 India’s Universal Immunisation Programme to prevent children from preventable disease: retention and dropout approach Diwakar Yadav, Chander Shekhar Abstract Background The Universal Immunisation Programme was integrated with the Reproductive and Child Health Programme to improve childhood immunisation in India. However, there is a lack of empirical research on understanding about childhood immunisation by the standard schedule of WHO. This study aimed to estimate the level of retention and dropouts from one vaccination to the next among Indian children aged 12–23 months. Methods We use data from the nationwide District Level Household and Facility Survey (DLHS-3), which was carried out in all 596 districts and covered 64 702 children aged 12–23 months in India during 2007–08. We used the Kaplan–Meier method to assess the retention rate of childhood immunisation. Findings Only 52·5% (33 959 of 64 702) of children aged 12–23 months have received the full course of vaccination. Children of the poorest and illiterate mothers have the lowest rate of full immunisation. 86·1% (55 688 of 64 702) of children would have been fully vaccinated if each child had been administered all three doses of diphtheria, pertussis, and tetanus (DPT) and polio vaccines and measles vaccine. The retention rate of childhood immunisation was in maximum decline between the second round of DPT and polio (70%, 95% CI 69–71) and the third round (56%, 55–57). On the other hand, if all children are brought under the health-system network by way of registering all births for BCG, the existing dropout rate at different stages of vaccination will yield 60·8% (33 869 of 55 688) of children being fully immunised. Interpretation The findings of this assessment reveal that immunisation coverage varies from one vaccine to another and declines over the schedule prescribed by the WHO. BCG, third-round DPT, and third-round polio vaccination coverage may play a critical role in full immunisation, as the dropout rates were higher for these vaccinations. Specially designed interventions are needed to meet Millennium Development Goals regarding the under-5 mortality rate, infant mortality rate, and proportion of 1-year-old children immunised against measles. Funding DY was supported by the Government of India/National Eligibility Test Doctoral Fellowship award from the University Grants Commission and Ministry of Health and Family Welfare, Government of India. The funders had no role in study design, data collection, analysis, or preparation of the abstract. Contributors DY devised the study, wrote the article, and led the analysis. CS helped to interpret the results and revise the analysis. All authors have seen and approved the final version of the abstract for publication. Conflicts of interest We declare that we have no conflicts of interest. Published Online June 17, 2013 FHI360, Monitoring and Evaluation Department, New Delhi, Delhi, India (D Yadav PhD); and Department of Mathematical Demography and Statistics, International Institute for Population Sciences, Mumbai, India (C Shekhar PhD) Correspondence to: Diwakar Yadav, FHI360, Monitoring and Evaluation Department, H-5 Green Park Extension, New Delhi, Delhi-110016, India [email protected]

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Meeting Abstracts

www.thelancet.com 151

India’s Universal Immunisation Programme to prevent children from preventable disease: retention and dropout approachDiwakar Yadav, Chander Shekhar

AbstractBackground The Universal Immunisation Programme was integrated with the Reproductive and Child Health Programme to improve childhood immunisation in India. However, there is a lack of empirical research on understanding about childhood immunisation by the standard schedule of WHO. This study aimed to estimate the level of retention and dropouts from one vaccination to the next among Indian children aged 12–23 months.

Methods We use data from the nationwide District Level Household and Facility Survey (DLHS-3), which was carried out in all 596 districts and covered 64 702 children aged 12–23 months in India during 2007–08. We used the Kaplan–Meier method to assess the retention rate of childhood immunisation.

Findings Only 52·5% (33 959 of 64 702) of children aged 12–23 months have received the full course of vaccination. Children of the poorest and illiterate mothers have the lowest rate of full immunisation. 86·1% (55 688 of 64 702) of children would have been fully vaccinated if each child had been administered all three doses of diphtheria, pertussis, and tetanus (DPT) and polio vaccines and measles vaccine. The retention rate of childhood immunisation was in maximum decline between the second round of DPT and polio (70%, 95% CI 69–71) and the third round (56%, 55–57). On the other hand, if all children are brought under the health-system network by way of registering all births for BCG, the existing dropout rate at diff erent stages of vaccination will yield 60·8% (33 869 of 55 688) of children being fully immunised.

Interpretation The fi ndings of this assessment reveal that immunisation coverage varies from one vaccine to another and declines over the schedule prescribed by the WHO. BCG, third-round DPT, and third-round polio vaccination coverage may play a critical role in full immunisation, as the dropout rates were higher for these vaccinations. Specially designed interventions are needed to meet Millennium Development Goals regarding the under-5 mortality rate, infant mortality rate, and proportion of 1-year-old children immunised against measles.

Funding DY was supported by the Government of India/National Eligibility Test Doctoral Fellowship award from the University Grants Commission and Ministry of Health and Family Welfare, Government of India. The funders had no role in study design, data collection, analysis, or preparation of the abstract.

Contributors DY devised the study, wrote the article, and led the analysis. CS helped to interpret the results and revise the analysis. All authors have seen and

approved the fi nal version of the abstract for publication.

Confl icts of interest We declare that we have no confl icts of interest.

Published OnlineJune 17, 2013

FHI360, Monitoring and Evaluation Department, New Delhi, Delhi, India (D Yadav PhD); and Department of Mathematical Demography and Statistics, International Institute for Population Sciences, Mumbai, India (C Shekhar PhD)

Correspondence to:Diwakar Yadav, FHI360, Monitoring and Evaluation Department, H-5 Green Park Extension, New Delhi, Delhi-110016, [email protected]