important for bicarbonate lecture

Upload: saramanae

Post on 04-Jun-2018

215 views

Category:

Documents


0 download

TRANSCRIPT

  • 8/13/2019 Important for Bicarbonate Lecture

    1/2

    February 2012

    Product Safety Summary of Sodium bicarbonate

    General statement

    This Product Safety Summary is intended toprovide a general overview of the chemical

    substance. It constitutes basic information and is

    not intended to provide emergency responseinformation, medical information, treatmentinformation or otherwise in-depth safety and

    health information, which can only be found in therelevant Safety Data Sheet (SDS) or the MaterialSafety Data Sheet (MSDS), as the case may be.

    Overall summary

    Sodium bicarbonate is an odorless whitecrystalline solid.

    The substance has a very wide range of

    applications, which include use in feed, cosmetics,pharmaceuticals, and industrial applications.

    Sodium bicarbonate is safe when ingested.

    However ingestion of large quantities may causeirritation of the intestine, nausea, vomiting, anddiarrhea. Sodium bicarbonate is not toxic when

    breathed in, or via skin contact. It is not irritatingto the skin or eye and does not provoke allergicreactions.

    It is not toxic following repeated exposure and has

    shown no indication of mutagenicity,carcinogenicity or effect on pre-natal development

    of the embryo and fetus in toxicological testing.

    Sodium bicarbonate is classified as Generally

    Recognized As Safe (GRAS) by the US Food and

    Drug Administration.

    Sodium bicarbonate is not considered to be toxic

    to the environment.

    Chemical identity

    Chemical name: Sodium hydrogen carbonate

    Common name: Baking soda

    CAS number: 144-55-8

    Molecular weight: 84 g/mol

    Uses

    Sodium bicarbonate has a very wide range ofapplications, which include use in feed, cosmetics,

    pharmaceuticals, and industrial applications. It

    can be used for example as a pH regulator, for therelease of CO2and as a mild abrasive.

    Physical properties

    Sodium bicarbonate is a white crystalline solidwithout any odor. It is neither flammable norexplosive.

    It is soluble in water (93.4 g/L at 20C and pH =

    8.4), non-volatile and decomposes at

    temperatures greater than 50C. In water, sodiumbicarbonate undergoes a complete dissociation

    into sodium and bicarbonate ions.

    Health effects

    When sodium bicarbonate comes into contact with

    body fluids, it dissociates into sodium and

    bicarbonate ions. Sodium is an essential nutrientand bicarbonate is a component of the buffer that

    regulates the acidity of the body. When ingested,

    sodium bicarbonate is neutralized in the stomachby the gastric acid.

    Sodium bicarbonate is safe when ingested.However ingestion of large quantities may cause

    irritation of the intestine, nausea, vomiting, and

    diarrhea. Sodium bicarbonate is not toxic whenbreathed in, or via skin contact. It is not irritatingto the skin or eye and does not provoke allergic

    reactions.

    It has no repeated dose toxicity as both sodium

    and bicarbonate ions have normal physiological

    roles in the body.

  • 8/13/2019 Important for Bicarbonate Lecture

    2/2

    February 2012

    There are no indications that sodium bicarbonatecauses genetic effects or cancer. Toxicological

    studies showed that sodium bicarbonate has no

    effect on the pre-natal development of theembryo and fetus.

    Sodium bicarbonate is classified as GenerallyRecognized As Safe (GRAS) by the US Food and

    Drug Administration.

    Environmental fate and impact

    Due to its high water solubility and low volatility,

    sodium bicarbonate will be found predominantly inthe aquatic environment.

    In water, sodium bicarbonate dissociates into

    sodium and bicarbonate ions. If the pH is

    decreased then carbonic acid (H2CO3or CO2) canbe formed. If the concentration of CO2in water isabove the water solubility limit, the CO2will

    distribute to the atmosphere. An addition ofbicarbonate to water will alter the pH towards avalue of 8.3.

    If sodium bicarbonate is emitted to soil, it will

    decompose to CO2and escape to the atmosphere,or precipitate as a calcium or metal carbonate,

    form complexes or stay in solution in water.

    Neither sodium nor bicarbonate has a tendency to

    adsorb to the particulate matter or surfaces and

    they do not accumulate in living tissues.

    Both sodium and bicarbonate have a wide natural

    occurrence.

    Risk of human exposure

    Exposure to sodium bicarbonate is possible in theworkplace environment during manufacturing and

    use. Workers handling the substance should followGood Industrial Hygiene Practicesand wear theappropriate personal protective equipment, as

    described in the Safety Data Sheet.

    Consumers may be exposed to sodiumbicarbonate since it is used in many different

    consumer products. Label instruction should be

    respected.

    Risk of environmental exposure

    Exposure of the environment can occur from the

    various industrial, professional, and consumer

    uses. However, sodium bicarbonate is notconsidered to be environmentally hazardous or

    toxic.

    Because of the mild alkaline nature of thesubstance, it is recommended to contain and

    isolate spills from waterways, sewers, and drains

    and dilute the residues with large amounts ofwater.

    Classification according to E.U. Regulation EC1272/2008 (CLP)

    Sodium bicarbonate is currently not listed inAnnex VI to EU Classification, Labeling and

    Packaging of Substances and Mixtures (CLP)

    Regulation (EC) No 1272/200. Furthermore, theavailable data show that there is no need to

    classify the substance as hazardous.

    More information

    If more information about safe use of sodium

    bicarbonate is required, please consult ourwebsite:click here.

    http://www.solvaychemicals.com/EN/products/bicar/default.aspx

    DisclaimerTo our present knowledge, the information contained herein isaccurate as of the date of this document. However, we do not make any

    warranty, express or implied, or accept any liability in connection with this

    information or its use. This information is for use by persons at their owndiscretion and risk and does not relate to the use of this product in

    combination with any other substance or any other process. This information

    gives typical properties only and is not to be used for specification purposes.This is not a license under any patent or other proprietary right. Some

    applications of this product may be regulated or restricted by applicable

    laws, regulations or other standards or norms, at national or internationallevel. The user alone must finally determine suitability of any information or

    material for any contemplated use, the manner of use in compliance with

    relevant legislations, standards or orders of any relevant authority, and

    whether any patents are infringed. We reserve our right to make additions,deletions, or modifications to the information at any time without prior

    notification.

    http://www.solvaychemicals.com/EN/products/bicar/default.aspxhttp://www.solvaychemicals.com/EN/products/bicar/default.aspxhttp://www.solvaychemicals.com/EN/products/bicar/default.aspxhttp://www.solvaychemicals.com/EN/products/bicar/default.aspxhttp://www.solvaychemicals.com/EN/products/bicar/default.aspxhttp://www.solvaychemicals.com/EN/products/bicar/default.aspxhttp://www.solvaychemicals.com/EN/products/bicar/default.aspx