sodium bicarbonate 8.4% (nahco3

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Sodium Bicarbonate 8.4% (NaHCO 3 ) McHenry Western Lake County EMS

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Page 1: Sodium Bicarbonate 8.4% (NaHCO3

Sodium Bicarbonate 8.4%

(NaHCO3)

McHenry Western Lake County

EMS

Page 2: Sodium Bicarbonate 8.4% (NaHCO3

Objectives

• During this session we will discuss:

• Class

• Actions

• Indications

• Contraindications

• Dosing/Routes

• How supplied

• Precautions

• Side effects

Page 3: Sodium Bicarbonate 8.4% (NaHCO3

Class:

• Alkalinizer (A substance, such as sodium

bicarbonate, used to boost the alkali

reserve artificially)

• Chemical Class: NaHCO3

Page 4: Sodium Bicarbonate 8.4% (NaHCO3

Actions:

• Bicarbonate ion buffers acidosis

• Raises serum pH

• ↓ uptake of cyclic antidepressants

• Shifts K+ into cells

Page 5: Sodium Bicarbonate 8.4% (NaHCO3

Indications:• Known preexisting hyperkalemia

• Known preexisting bicarbonate-responsive acidosis (DKA, OD of tricyclic & other Na channel blocking agents; ASA OD, cocaine, or diphenhydramine

• Prolonged resuscitation with effective ventilation; upon return of spontaneous circulation after long arrest interval

• Crush Syndrome

Page 6: Sodium Bicarbonate 8.4% (NaHCO3

Dosing/Routes:

• TCA OD; Cardiac arrest w/ pre existing

acidosis:1mEq/kg (1ml/kg) IVP/IO (max 50

mEq).

• May repeat full dose and more in cyclic

antidepressant OD

• Renal/Dialysis patients w/hyperkalemia or

Crush Syndrome: 50 mEq slow IVP over 5

min.

Page 7: Sodium Bicarbonate 8.4% (NaHCO3

Dosing/Routes

• NOTE!!

• Check IV patency before infusing.

• Flush IV before and after giving.

Page 8: Sodium Bicarbonate 8.4% (NaHCO3

How supplied:

• 50 mEq/50ml

Page 9: Sodium Bicarbonate 8.4% (NaHCO3

Contraindications:

• None when used in treatment of documented

metabolic acidosis with effective ventilations.

• Alkalosis

• Inability to ventilate acidotic patient

• Not useful or effective in hypercarbic acidosis

(cardiac arrest and CPR without intubation)

Page 10: Sodium Bicarbonate 8.4% (NaHCO3

Precautions:

• Don’t mix with catecholamine's or calcium

agents.

• The most abundant catecholamine's are

epinephrine (adrenaline), norepinephrine

(noradrenaline) and dopamine

• From Wikipedia.org

Page 11: Sodium Bicarbonate 8.4% (NaHCO3

Side effects/adverse reactions:

• Electrolyte: Metabolic alkalosis, ↑ Na ↓ K, hyperosmolality, ↓ Ca.

• Shifts oxyhemaglobin dissociation curve to the L.

• Inhibits o2 release to the tissues

• CV: ↓ VF threshold; impaired cardiac function

• Skin: Tissue necrosis with infiltration at IV site.

• Ref: MWLCEMS Protocol and 2000 Mosby’s Nursing Drug Reference Book

Page 12: Sodium Bicarbonate 8.4% (NaHCO3

Case Study

• You are at a Cardiac Arrest of a known

dialysis patient and she has been

unresponsive to resuscitative efforts. You

have a patent IV line, your first dose of

Sodium Bicarb would be?

Page 13: Sodium Bicarbonate 8.4% (NaHCO3

Answer

• 50 mEq/kg IVP/IO over 5 min

Page 14: Sodium Bicarbonate 8.4% (NaHCO3

Question?

• You are considering what condition with

this patient.

Page 15: Sodium Bicarbonate 8.4% (NaHCO3

Answer

• Hyperkalemia