hpc data year 201 update - 09/10/2017 report 2017 eurocet european network of competent authorities...
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09/10/2017Last update -
Report 2017
EUROCETEuropean Network of CompetentAuthorities for Tissues and Cells
HPC DATAYear 2016
PLEASE CHECK THE WEBSITE FOR POSSIBLE UPDATES
European Network of Competent Authorities for Tissues and Cells
Report 2017
This document has been produced and published by EUROCET (www.eurocet.org) with the data collected
by Competent Authorities for Haematopoietic Progenitor Cells from European Member States (and other
Extra EU countries).
The following report shows calculations regarding the whole donation‐processing‐distribution‐
transplantation process of Haematopoietic Progenitor Cells of human origin for year 2016.
This year 25 countries joined the collection and provided data ‐ 23 EU Member States and 2 Extra EU
countries. (Appendix I)
This report is divided into four main sections based on the competence of the data presented. In each
section, data are shown in tables concerning different aspects of the related activity:
‐ Donor Registries1
The data is divided into four sections:
o POTENTIAL DONATION: In the first table, the stream of potential HPC donors and HPC cord blood units in the year of reference has been reported. This data is represented by the number available at the beginning of the year, the entries/exits during the year and the number available at the end of the year, in the registries.
o SEARCHING IN THE NATIONAL REGISTRIES: This section’s data is shown in three different tables:
one reports the number of searches requested by origin of the request (from the own country, from a EU country, from an EXTRA EU country), while the following table reports the number of the searches performed both in the national registries (searches from the own country, from a EU country, from an EXTRA EU country) and the foreign registries for one’s own country. The last table collects the number of the unrelated donations by origin (unrelated donation from the own country, from a EU country, from an EXTRA EU country), the number of unrelated donations by request from EU countries and the unrelated donations by request from EXTRA EU countries.
o IMPORT – EXPORT: One table is completed with the data relative to the total of HPC bags imported
and exported, with details of the origin/destination INTRA or EXTRA EU.
‐ Donation Centers: This section collects data on the number of HPC donation and the number of
donated bags. The data is divided into four tables:
HPC Donation per TYPE: it includes the number of HPC donations, divided per type: autologous and allogenic (related and unrelated) and the respective total.
o HPC Donation per SOURCE: it shows the number of donation by HPC source (Bone Marrow, Peripheral Blood, Cord Blood).
1 Donor Registries: see Glossary, Appendix II
European Network of Competent Authorities for Tissues and Cells
o BAGS per TYPE: it includes the respective number of donated HPC bags, divided per type: autologous and allogenic (related and unrelated) with their total.
o BAGS per SOURCE: it reports the same data on the bags by HPC source (Bone Marrow, Peripheral Blood, Cord Blood).
‐ Cord Blood Banks2
This section includes data on CORD BLOOD BANKING and is made up by three tables, respectively:
o HPC CORD BLOOD BANKING: it is a picture of the stream of units, starting from the number available at the bank, at the beginning of the year; the units collected/discarded/distributed over the course of the year, the number of units available at the end of the year and Stored and completed of HLA typing at 31/12 by type (related and unrelated units).
o UNRELATED CORD BLOOD per ORIGIN: it reports the data on unrelated cord blood banking only, by number of units per origin (from own country, from EU country, from Extra EU country).
o RELATED CORD BLOOD per ORIGIN: it reports the data on related cord blood banking only, by number of units per origin (from own country, from EU country, from Extra EU country).
- Transplant Centers
This section includes two tables on transplantation with data on the total number of transplants and recipients.
o TRANSPLANTATION and RECIPIENTS per type (number): it shows the number of first transplants and the number of recipients, by type of HPC (autologous, allogenic: related and unrelated) and the total.
o TRANSPLANTATION and RECIPIENTS per HPC's ORIGIN: it shows the number of first transplants and the number of recipients, by type of HPC (autologous, allogenic: related and unrelated) and also by HPC’s origin (Bone Marrow, Peripheral Blood and Cord Blood).
In order to provide readers with a better understanding of the reports and hoping in further future
harmonisation of terms and definitions of the single data at international level at the end of this report a
short glossary has been included intended to clarify the meaning of the data shown by the tables (Appendix
II).
This glossary has been updated with definitions from both the “EU directive 24/2003 of the European
Parliament and of the Council of 31 March 2004 on setting standards of quality and safety for the donation,
procurement, testing, processing, preservation, storage and distribution of human tissues and cells” and
the “Guide to the quality and safety of tissues and cells for human application, 3rd Edition, 2017” by the
Council of Europe.
Eurocet team
2Cord Blood Banks: See Glossary, Appendix II
Eurocet Registry
Potential donation
Section 1: Donor Registries
Exit in the yearHPC potential donor
Enter in the year Registered at 01/01 00:00
Year HPC Cord blood units
Registered at 31/12 24:00HPC potential donor HPC Cord blood units HPC potential donor HPC Cord blood units HPC potential donor HPC Cord blood units
MEMBER STATES OF EU
AT AUSTRIA 2016
BG BULGARIA 2016
HR CROATIA 2016 301647703 3600 3237200 1222 47103
CY CYPRUS 2016 3294136108 9142 3635360 3344 144890
CZ CZECH REPUBLIC 2016 414985970 9729 4173979 226 94720
EE ESTONIA 2016 0 000
FI FINLAND 2016 334531164 2678 3344727 10 33119
FR FRANCE 2016 34115248671 20455 351035896 1751163 263343
DE GERMANY 2016
HU HUNGARY 2016
IT ITALY 2016 33450361413 29825 3445310644 381041 380594
LV LATVIA 2016
LT LITHUANIA 2016 134110738 14720131 11440
MT MALTA 2016 00 0 00 00 0
NL NETHERLANDS 2016 364881672 4237132723
PL POLAND 2016
PT PORTUGAL 2016 9157385323 12451 92362206 16671746 395568
RO ROMANIA 2016 013288 9371 0273 00 22386
SK SLOVAKIA 2016 17306764 3747 174520 520 10491
SI SLOVENIA 2016 34317033
ES SPAIN 2016 62407200678 47940 642901684 2552138 147049
SE SWEDEN 2016 4491 46348756
UK UNITED KINGDOM 2016
Total year 2016 1609492 164143 148938 7587 22989 7587 1700459 7587
OTHER COUNTRIES
MD MOLDOVA 2016 00 0 00 00 0
NO NORWAY 2016 32450 3031 2559 32927
Total year 2016 32450 0 3031 0 2559 0 32927 0
Empty fields:The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Section 1: Donor Registries Page 1 of 6
Eurocet Registry
Searching in the National Registries
Section 1: Donor Registries
own COUNTRY
TOTAL
searching
requested
Year ORIGIN of REQUEST
1 - SEARCHING REQUESTED (number)
other EU country extra EU country
MEMBER STATES OF EU
AUSTRIA 2016AT
BULGARIA 2016 0 0 0 0BG
CROATIA 2016 107 107 220 434HR
CYPRUS 2016 59 6004 5845 22292CY
CZECH REPUBLIC 2016 479 13710 37172 51361CZ
ESTONIA 2016EE
FINLAND 2016 6563 17888 24451FI
FRANCE 2016 1968 6290 17847 26105FR
GERMANY 2016DE
HUNGARY 2016HU
ITALY 2016 1747 806 726 3279IT
LATVIA 2016LV
LITHUANIA 2016LT
MALTA 2016 0 0 0 0MT
NETHERLANDS 2016 565 0 0 565NL
POLAND 2016PL
PORTUGAL 2016 245 1551 905 2701PT
ROMANIA 2016 91 111 99 301RO
SLOVAKIA 2016 73 6267 16627 22967SK
SLOVENIA 2016SI
SPAIN 2016 2244ES
SWEDEN 2016SE
UNITED KINGDOM 2016UK
Total year 2016 5334 41409 97329 156700
OTHER COUNTRIES
MOLDOVA 2016 0 0 0 0MD
NORWAY 2016NO
Total year 2016 0 0 0 0
Page 2 of 6Section 1: Donor Registries
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet Registry
Section 1: Donor Registries
Searching in the National Registries
2 - SEARCHING PERFORMED (number)- IN THE NATIONAL REGISTRYYear - IN THE FOREIGN REGISTRY
Totalfor own
COUNTRY
for other
EU country
for extra
EU country
Total for own COUNTRY
MEMBER STATES OF EU
AUSTRIA 2016AT
BULGARIA 2016 0 0 0 0BG
CROATIA 2016 107 220107 434 99HR
CYPRUS 2016 6004 584534 22260 32CY
CZECH REPUBLIC 2016 13710 37172479 51361 439CZ
ESTONIA 2016 0 00 0EE
FINLAND 2016 6563 17888 24451FI
FRANCE 2016 6290 178471968 26105 1930FR
GERMANY 2016DE
HUNGARY 2016HU
ITALY 2016 806 7261747 3279 1747IT
LATVIA 2016LV
LITHUANIA 2016LT
MALTA 2016 0 00 0 0MT
NETHERLANDS 2016 0 00 0 0NL
POLAND 2016PL
PORTUGAL 2016 1551 905245 2701 245PT
ROMANIA 2016 111 9991 301 90RO
SLOVAKIA 2016 18 873 99 73SK
SLOVENIA 2016SI
SPAIN 2016ES
SWEDEN 2016SE
UNITED KINGDOM 2016UK
Total year 2016 4744 35160 130991 465580710
OTHER COUNTRIES
MOLDOVA 2016 0 00 0 0MD
NORWAY 2016 7348 7348 112NO
Total year 2016 7348 0 7348 1120
Section 1: Donor Registries Page 3 of 6
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet Registry
Section 1: Donor Registries
HPC donation from National Registries
Total
unrelated
donation
Total unrelated
donation for
COUNTRY
request
COUNTRY
to
country
Total
unrelated
donation for
EU request
Year
EU
to
country
EXTRA
EU to
country
3 - UNRELATED DONATION (number)Total
unrelated
donation for
EXTRA EU
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016 0 0BULGARIA 0 0
CY 2016 46 8 1 7 0CYPRUS 27 6
CZ 2016 158 92 30 130 4CZECH REPUBLIC 59 5
DE 2016GERMANY
EE 2016ESTONIA
ES 2016 699 472 78 284 110SPAIN 90 137
FI 2016FINLAND
FR 2016 1261 1099 197 732 170FRANCE 83 79
HR 2016 53 52 6 42 4CROATIA 0 1
HU 2016HUNGARY
IT 2016 818 756 148 448 160ITALY 48 14
LT 2016 57 57 14 42 1LITHUANIA
LV 2016LATVIA
MT 2016 0 0 0 0 0MALTA 0 0
NL 2016 392 392 18 295 79NETHERLANDS 0 0
PL 2016POLAND
PT 2016 115 67 18 41 8PORTUGAL 34 14
RO 2016 6 5 1 4 0ROMANIA 1 0
SE 2016SWEDEN
SI 2016 26 0 0 26 0SLOVENIA 26 0
SK 2016 39 39 0 38 1SLOVAKIA 0 0
UK 2016UNITED KINGDOM
Total year 2016 3670 3039 511 5372089 368 256
OTHER COUNTRIES
MD 2016 0 0 0 0 0MOLDOVA 0 0
NO 2016 27 10 10NORWAY 14 3
Total year 2016 27 10 10 00 14 3
Section 1: Donor Registries
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Page 4 of 6
Eurocet Registry
Section 1: Donor Registries
HPC Import/Export
INTRA EU EXTRA EU TOTAL
IMPORT
INTRA EU EXTRA EU TOTAL
EXPORTYear
4 - IMPORT/EXPORT of UNRELATED BAGS (number)
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016 10 0 10 0 0 0BULGARIA
CY 2016 33 6 39CYPRUS
CZ 2016 59 5 64 11 5 16CZECH REPUBLIC
DE 2016 365 207 572 2954 2345 5299GERMANY
EE 2016 16 1 17 0 0 0ESTONIA
ES 2016 275 119 394 90 137 227SPAIN
FI 2016 7 78 85 7 1 8FINLAND
FR 2016 910 221 1131 100 87 187FRANCE
HR 2016 43 3 46 0 1 1CROATIA
HU 2016 77 2 81 2 0 2HUNGARY
IT 2016 457 174 631 65 31 96ITALY
LT 2016 42 1 43 1 1 2LITHUANIA
LV 2016LATVIA
MT 2016 0 0 0 0 0 0MALTA
NL 2016 295 79 374 23 14 37NETHERLANDS
PL 2016POLAND
PT 2016 22 4 26 38 14 52PORTUGAL
RO 2016 71 4 75 150 229 379ROMANIA
SE 2016 131 22 153 17 16 33SWEDEN
SI 2016SLOVENIA
SK 2016 34 0 34 14 0 14SLOVAKIA
UK 2016 18027 1810 19837 45427 233 45659UNITED KINGDOM
Total year 2016 20841 2730 23573 48932 3120 52051
OTHER COUNTRIES
MD 2016 0 0 0 0 0 0MOLDOVA
NO 2016 73 17NORWAY
Total year 2016 0 0 73 0 0 17
Section 1: Donor Registries Page 5 of 6
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet RegistrySection 1: Donor Registries
HPC Import/Export
IMPORT EXPORT
5 - IMPORT/EXPORT of UNRELATED BAGS per SOURCE* (number)
INTRA EU
BM PB CB
EXTRA EU
BM PB CB
INTRA EU
BM PB CB
EXTRA EU
BM PB CB
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016 2 8 0 0 0 0BULGARIA 0 2 0 0 0
CY 2016CYPRUS 0 33 0 0 4 2
CZ 2016 14 112 0 3 7 0CZECH REPUBLIC 1 15 0 1 4 0
DE 2016 17 347 1 38 167 2GERMANY 541 2387 26 470 1831 44
EE 2016 2 14 0 0 1 0ESTONIA 0 0 0 0 0 0
ES 2016 50 220 5 21 89 9SPAIN 1 28 61 5 12 120
FI 2016 2 4 1 8 69 1FINLAND 0 6 1 0 1 0
FR 2016 243 620 47 77 109 35FRANCE 29 38 33 5 21 61
HR 2016 9 34 0 1 2 0CROATIA 0 0 0 1 0 0
HU 2016 13 64 2 0HUNGARY 0 2 0 0
IT 2016 144 304 9 41 119 14ITALY 13 35 17 3 11 17
LT 2016 5 36 0 0 1 0LITHUANIA 0 1 0 0 1 0
LV 2016LATVIA
MT 2016 0 0 0 0 0 0MALTA 0 0 0 0 0 0
NL 2016 24 233 38 4 44 31NETHERLANDS 7 15 1 5 8 1
PL 2016POLAND
PT 2016 3 15 4 1 3 0PORTUGAL 10 28 0 3 11 0
RO 2016 12 59 0 0 4 0ROMANIA 24 126 0 36 193 0
SE 2016 18 113 0 7 15 0SWEDEN 1 12 4 3 9 4
SI 2016SLOVENIA
SK 2016 4 30 0 0 0 0SLOVAKIA 0 12 2 0 0 0
UK 2016 1386 6901 9740 40 162 1608UNITED KINGDOM 1071 12285 32071 22 171 40
Total year 2016 1948 9114 243 792 1700 16989845 15025 32216 554 2277 289
OTHER COUNTRIES
MD 2016 0 0 0 0 0 0MOLDOVA 0 0 0 0 0 0
NO 2016 24 31 1 9 8NORWAY 2 12 3
Total year 2016 24 31 9 8 0 21 12 0 0 3 0
BM
PB = Peripheral Blood
= Bone Marrow
CB = Cord Blood
* Legenda
Section 1: Donor Registries Page 6 of 6
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet Registry
Section 2: Donation Centers
HPC Donation Autologous and Allogenic
Autologous
Related
Year Unrelated
1 - DONATION per TYPE (number)Allogenic
Total
Total donation
MEMBER STATES OF EU
AT 2016 19177AUSTRIA
BG 2016 19551946 9 0BULGARIA 9
CY 2016 6721 2 44CYPRUS 46
CZ 2016 289135 46 108CZECH REPUBLIC 154
DE 2016 123504417 932 7001GERMANY 7933
EE 2016 6156 5 0ESTONIA 5
ES 2016 30391975 760 304SPAIN 1064
FI 2016 394329 44 31FINLAND 75
FR 2016 45773328 890 359FRANCE 1249
HR 2016 1149495 37 617CROATIA 654
HU 2016 524374 77 73HUNGARY 150
IT 2016 59804542 1190 248ITALY 1438
LT 2016 323292 22 9LITHUANIA 31
LV 2016LATVIA
MT 2016 00 0 0MALTA 0
NL 2016 34723233 181 58NETHERLANDS 239
PL 2016POLAND
PT 2016 2361457 87 1817PORTUGAL 1904
RO 2016 29732947 20 6ROMANIA 26
SE 2016 1756769 103 884SWEDEN 987
SI 2016 15 86SLOVENIA
SK 2016 36983658 37 3SLOVAKIA 40
UK 2016 301368306 7304 14526UNITED KINGDOM 21830
Total year 2016 9428137834 261741176137280
OTHER COUNTRIES
MD 2016 00 0 0MOLDOVA 0
NO 2016 10824 30 54NORWAY 84
Total year 2016 10884 543024
Section 2: Donation Centers
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Page 1 of 4
Eurocet RegistrySection 2: Donation Centers
HPC Donation Autologous and Allogenic
CBPBBMCBPBBM
TOTAL donation TOTAL
Allo
CBPBBM
UnrelatedRelated
Allogenic
Year
Autologous
2 - DONATION per SOURCE of HPC* (number)
CBPBBM
MEMBER STATES OF EU
AT 2016AUSTRIA 307 18547 323
BG 2016 1 1851 1BULGARIA 94 20 99 0 00 103 1851
CY 2016 0CYPRUS 21 20 462 2 34442 65 344
CZ 2016 3 0 2CZECH REPUBLIC 132 85 15439 3 9510 181 100
DE 2016 22 0 181GERMANY 4395 14750 7933751 1272 05729 10875 0
EE 2016 1 0 1ESTONIA 55 20 54 0 00 59 0
ES 2016 3 63SPAIN 1972 771064697 11 20687 2756 206
FI 2016 15 0 5FINLAND 314 140 7539 4 027 380 0
FR 2016 9 286FRANCE 3319 3401249604 45 154160 4083 154
HR 2016 0 352 12CROATIA 143 146 65419 2 6105 167 968
HU 2016 0 13HUNGARY 374 270 15064 14 059 497
IT 2016 15 4 424ITALY 4523 510187 1438579 71 38139 5241 229
LT 2016 0 138 5LITHUANIA 154 100 3117 5 04 175 138
LV 2016LATVIA
MT 2016 0 0 0MALTA 0 00 00 0 00 0 0
NL 2016 22 779 43NETHERLANDS 2432 792 239136 14 638 2606 787
PL 2016POLAND
PT 2016 3 0 16PORTUGAL 454 350 190471 16 174655 580 1746
RO 2016 0 2847 0ROMANIA 100 1378 2620 1 05 125 3225
SE 2016 4 44 23SWEDEN 721 450 98780 18 756110 911 800
SI 2016 0SLOVENIA 015 0 086
SK 2016 0 3524 4SLOVAKIA 134 412 4021 0 03 158 3536
UK 2016 73 2667 259UNITED KINGDOM 5566 6725846 218301199 340 120512135 8900 20564
Total year 2016 171 24903 12206 1338 4366 6436 1818 8694 16006 37834 34971564093624
OTHER COUNTRIES
MD 2016 0 0 0MOLDOVA 0 00 00 0 00 0 0
NO 2016 14NORWAY 328 288421 14 40 389
Total year 2016 0 328 0 14 21 0 14 40 0 84 038928
BM
PB = Peripheral Blood
= Bone Marrow
CB = Cord Blood
* Legenda
Section 2: Donation Centers Page 2 of 4
Empty fields:The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet Registry
Section 2: Donation Centers
HPC Donation Autologous and Allogenic
Autologous
Related
Yea Unrelated
3 - BAGS per TYPE of DONATION (number)Allogenic
Total
Total donation
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016BULGARIA
CY 2016 00 0CYPRUS 0
CZ 2016 317184 60 73CZECH REPUBLIC 133
DE 2016 3221422788 1128 8298GERMANY 9426
EE 2016 290284 6 0ESTONIA 6
ES 2016SPAIN
FI 2016FINLAND
FR 2016 69285437 1058 433FRANCE 1491
HR 2016 1149495 37 617CROATIA 654
HU 2016 45744446 64 64HUNGARY 128
IT 2016 3091229474 1190 248ITALY 1438
LT 2016LITHUANIA
LV 2016LATVIA
MT 2016 00 0 0MALTA 0
NL 2016NETHERLANDS
PL 2016POLAND
PT 2016PORTUGAL
RO 2016 46424074 562 6ROMANIA 568
SE 2016 1828893 97 838SWEDEN 935
SI 2016SLOVENIA
SK 2016 53075239 30 38SLOVAKIA 68
UK 2016 20647UNITED KINGDOM
Total year 2016 10880814847 10615423273314
OTHER COUNTRIES
MD 2016 00 0 0MOLDOVA 0
NO 2016 7979NORWAY
Total year 2016 790 0079
Section 2: Donation Centers
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Page 3 of 4
Eurocet RegistrySection 2: Donation Centers
HPC Donation Autologous and Allogenic
CBPBBMCBPBBM
TOTAL BAGS TOTAL
Allo
CBPBBM
UnrelatedRelated
Allogenic
Year
Autologous
4 - BAGS per SOURCE of HPC* (number)
CBPBBM
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016 1851BULGARIA 0 0 1851
CY 2016 0CYPRUS 20 02 2 34442 44 344
CZ 2016 3 0 2CZECH REPUBLIC 181 810 13348 3 5812 241 68
DE 2016 22 13998 182GERMANY 8768 148930 9426916 1285 10046009 15693 15032
EE 2016 1 0 1ESTONIA 283 20 65 0 00 288 0
ES 2016SPAIN
FI 2016 0FINLAND 0 0 0
FR 2016 9 286FRANCE 5428 3811491772 86 155192 6392 155
HR 2016 0 352 12CROATIA 143 146 65419 2 6105 167 968
HU 2016 0 3552 38HUNGARY 894 970 12826 59 05 925 3552
IT 2016 15 4 424ITALY 29455 510187 1438579 71 38139 30173 229
LT 2016LITHUANIA
LV 2016LATVIA
MT 2016 0 0 0MALTA 0 00 00 0 00 0 0
NL 2016NETHERLANDS
PL 2016POLAND
PT 2016PORTUGAL
RO 2016 0 3988 0ROMANIA 86 1545 56817 1 05 108 4533
SE 2016 4 44 20SWEDEN 845 340 93577 10 75672 994 800
SI 2016SLOVENIA
SK 2016 0 4998 2SLOVAKIA 241 224 684 0 038 283 5022
UK 2016UNITED KINGDOM 381 6841 13425
Total year 2016 54 46324 28787 967 2465 802 1519 6519 2965 4597962149292114847
OTHER COUNTRIES
MD 2016 0 0 0MOLDOVA 0 00 00 0 00 0 0
NO 2016NORWAY 392 10 402
Total year 2016 0 392 0 0 10 0 0 0 0 040200
BM
PB = Peripheral Blood
= Bone Marrow
CB = Cord Blood
* Legenda
Section 2: Donation Centers Page 4 of 4
Empty fields:The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet Registry
Section 3: Cord Blood Banks
HPC Cord Blood Banking (units)
UnrelatedRelated
Storaged at 01/01 00:00
Year UnrelatedRelated
Collected
UnrelatedRelated
Discarded
UnrelatedRelated
Distributed Storaged at 31/12 00:00
UnrelatedRelated
Storaged with HLA typing at 31/12
UnrelatedRelated
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016 0 0 0BULGARIA 0 00 00 00 0
CY 2016 20498 3400 344CYPRUS 3294 3635252 241500 3 3086
CZ 2016 167 5 95CZECH REPUBLIC 4610 46310 17274 00
DE 2016 174 30 1007GERMANY 35814 368620 5951 01
EE 2016 0 0 0ESTONIA 0 00 00 00 0 0
ES 2016 2152SPAIN 62407 6429035 220
FI 2016 0 0 0FINLAND 3345 33440 01 00
FR 2016 1163FRANCE 35115 3510320 154
HR 2016 196 6 610CROATIA 3231 33190 202522 00
HU 2016 35838 3552 0HUNGARY 0 0131 392570 02
IT 2016 3062 187 14661ITALY 39662 9833 18413678 387 184 983
LT 2016 1098 138 0LITHUANIA 0 07 12290 00 1229 0
LV 2016LATVIA
MT 2016 0 0 0MALTA 0 00 00 00 0 0
NL 2016 2 432NETHERLANDS 1050
PL 2016 416POLAND 4029 4358241 26
PT 2016 151 0 1778PORTUGAL 9159 92171 1501708 40
RO 2016 109795 11094 0ROMANIA 0 -6344 1205456 00
SE 2016 59 44 756SWEDEN 4491 46345 118397 80
SI 2016 343SLOVENIA 343
SK 2016 0 17 0SLOVAKIA 0 00 120 05 0 1745
UK 2016 13425UNITED KINGDOM 283256 28123610782 41811
Total year 2016 171038 488413 18475 37182 743 27465 15 42369 186614 58141413451949
OTHER COUNTRIES
MD 2016 0 0 0MOLDOVA 0 00 00 00 0 0
NO 2016NORWAY
Total year 2016 0 0 0 0 0 0 0 0 0 000
Section 3: Cord Blood Banks Page 1 of 3Empty fields: The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet Registry
Section 3: Cord Blood Banks
HPC Cord Blood Banking 1 - UNRELATED CORD BLOOD per ORIGIN (units)
Storaged at 01/01 00:00
Year
Collected Discarded Distributed Storaged at 31/12 00:00
from own
Country
from
other EU
from EXTRA
EU country
from own
Country
from
other EU
from EXTRA
EU country
from own
Country
from
other EU
from EXTRA
EU country
from own
Country
from
other EU
from EXTRA
EU country
from own
Country
from
other EU
from EXTRA
EU country
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016 0BULGARIA 0 00 00 0 0 0 0 0
CY 2016 3294 0 344CYPRUS 0 30 00 00 0 0 3635 0 0
CZ 2016 4610 0 95CZECH REPUBLIC 0 00 00 074 0 0 4631 0 0
DE 2016 1004GERMANY 1 2
EE 2016 0 0 0ESTONIA 0 00 00 00 0 0 0 0 0
ES 2016 62407 2138SPAIN 2065 9 35 5 9 64290
FI 2016 3345 0 0FINLAND 0 00 00 01 0 0 3344 0 0
FR 2016 35115 0 1163FRANCE 0 1540 00 020 0 0 35103 0 0
HR 2016 3231 0 610CROATIA 0 00 00 0522 0 0 3319 0 0
HU 2016 0 0 0HUNGARY 0 00 00 00 0 0 0 0 0
IT 2016 39662 14661ITALY 3813678 983
LT 2016 0 0 0LITHUANIA 0 00 00 00 0 0 0 0 0
LV 2016LATVIA
MT 2016 0 0 0MALTA 0 00 00 00 0 0 0 0 0
NL 2016 366NETHERLANDS 10344 22 1 1
PL 2016 411POLAND 2 3
PT 2016 9157 1775PORTUGAL 2 03 01708 4 9216 1
RO 2016 0 0 0ROMANIA 0 0 00 06 -6 0 0
SE 2016 4491 0 756SWEDEN 0 80 00 0397 0 0 4634 0 0
SI 2016 343SLOVENIA 343
SK 2016 0 0 0SLOVAKIA 0 00 00 00 0 0 0 0 0
UK 2016UNITED KINGDOM
Total year 2016 165312 2 0 23666 55 36 16441 0 0 1010512 01129492
OTHER COUNTRIES
MD 2016 0 0 0MOLDOVA 0 00 00 00 0 0 0 0 0
NO 2016NORWAY
Total year 2016 0 0 0 0 0 0 0 0 0 000 000
Empty fields: The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Section 3: Cord Blood Banks Page 2 of 3
Eurocet Registry
Section 3: Cord Blood Banks
HPC Cord Blood Banking 2 - RELATED CORD BLOOD per ORIGIN (units)
Storaged at 01/01 00:00
Year
Collected Discarded Distributed Storaged at 31/12 00:00
from own
Country
from
other EU
from EXTRA
EU country
from own
Country
from
other EU
from EXTRA
EU country
from own
Country
from
other EU
from EXTRA
EU country
from own
Country
from
other EU
from EXTRA
EU country
from own
Country
from
other EU
from EXTRA
EU country
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016 0BULGARIA 0 00 00 0 0 0 0 0 0
CY 2016 15642 2037 2350CYPRUS 2819 0860 17190 97138 0 0 18130 3776 2244
CZ 2016 167 0 5CZECH REPUBLIC 0 00 00 00 0 0 172 0 0
DE 2016 30GERMANY 0 0
EE 2016 0 0 0ESTONIA 0 00 00 00 0 0 0 0 0
ES 2016SPAIN
FI 2016 0 0 0FINLAND 0 00 00 00 0 0 0 0 0
FR 2016FRANCE
HR 2016 196 0 6CROATIA 0 00 00 00 0 0 202 0 0
HU 2016 35838 3552HUNGARY 2131 39257
IT 2016 3062 187ITALY 73 184
LT 2016 917 0 138LITHUANIA 181 00 00 07 0 0 1048 181 0
LV 2016LATVIA
MT 2016 0 0 0MALTA 0 00 00 00 0 0 0 0 0
NL 2016 2NETHERLANDS 00 0 0 0
PL 2016POLAND
PT 2016 151 0PORTUGAL 01 150
RO 2016 100405 320 10606ROMANIA 9070 421 567 2346 110665 9489 382
SE 2016 59 0 44SWEDEN 0 00 00 05 0 0 118 0 0
SI 2016SLOVENIA
SK 2016 0 0 17SLOVAKIA 0 50 00 00 0 0 12 0 0
UK 2016UNITED KINGDOM
Total year 2016 156437 12070 2357 16937 1281 257 631 99 22 0014 262613446169938
OTHER COUNTRIES
MD 2016 0 0 0MOLDOVA 0 00 00 00 0 0 0 0 0
NO 2016NORWAY
Total year 2016 0 0 0 0 0 0 0 0 0 000 000
Empty fields: The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Section 3: Cord Blood Banks Page 3 of 3
Eurocet Registry
Section 4: Transplant Centers
HPC Transplantation
Transplants Recipients
AUTOLOGOUS
ALLOGENICYear
1 - Tranplantation and Recipient per type (number)
Transplants Recipients Transplants Recipients
RELATED UNRELATED
Total
Transplants Recipients
MEMBER STATES OF EU
AT 2016AUSTRIA 0 0
BG 2016 64 53 9 9 10 10BULGARIA 83 72
CY 2016 21 21CYPRUS 21 21
CZ 2016 470 368 100 93 170 159CZECH REPUBLIC 740 620
DE 2016 4620 3734 973 906 2151 2028GERMANY 7744 6668
EE 2016 52 5 15ESTONIA 72 0
ES 2016 1975 760 481SPAIN 3216 0
FI 2016 261 171FINLAND 0 432
FR 2016 3151 3043 898 1060FRANCE 5109 3043
HR 2016 171 134 26 23 49 41CROATIA 246 198
HU 2016HUNGARY 0 0
IT 2016 2896 2355 1010 908 786 755ITALY 4692 4018
LT 2016 154 154 16 16 48 48LITHUANIA 218 218
LV 2016LATVIA 0 0
MT 2016 0 0 0 0 0 0MALTA 0 0
NL 2016 3433 990 170 162 409 407NETHERLANDS 4012 1559
PL 2016POLAND 0 0
PT 2016 395 375 68 66 72 69PORTUGAL 535 510
RO 2016 147 146 31 30 33 33ROMANIA 211 209
SE 2016 566 535 100 89 183 177SWEDEN 849 801
SI 2016 86 15 26SLOVENIA 127 0
SK 2016 133 103 32 31 46 43SLOVAKIA 211 177
UK 2016UNITED KINGDOM 0 0
Total year 2016 18334 12272 4213 2333 5539 3941 28086 18546
OTHER COUNTRIES
MD 2016 0 0 0 0 0 0MOLDOVA 0 0
NO 2016 73 73NORWAY 73 73
Total year 2016 0 0 0 0 73 73 73 73
Section 4: Transplant Centers Page 1 of 3
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet Registry
Section 4: Transplant Centers
HPC Transplantation 2 - Tranplantation and Recipient per source of HPC (number)
AUTOLOGOUS
Year
Tranplant
Cord BloodPeripheral BloodBone Marrow
Recipient Tranplant Recipient Tranplant Recipient Tranplant
Cord BloodPeripheral BloodBone Marrow
Recipient Tranplant Recipient Tranplant Recipient Tranplant
Cord BloodPeripheral BloodBone Marrow
Recipient Tranplant Recipient Tranplant Recipient
ALLOGENIC
UnrelatedRelated
MEMBER STATES OF EU
AT 2016AUSTRIA
BG 2016 53 0 1BULGARIA 0 21 08 08 2 8 8 0 06400
CY 2016 21 0CYPRUS 0 002100
CZ 2016 368 0 7CZECH REPUBLIC 0 147 093 086 14 156 145 0 046901
DE 2016 3729 0 172GERMANY 0 238164 4796 5738 224 1911 1802 2 2461555
EE 2016 0 1ESTONIA 0 204 0 13 0 0511
ES 2016 63SPAIN 82697 363 3819723
FI 2016FINLAND
FR 2016 283FRANCE 0 182611 4 781 9731474
HR 2016 134 0 12CROATIA 0 119 014 014 10 38 31 0 017100
HU 2016HUNGARY
IT 2016 2342 0 424ITALY 1 242400 6579 7502 234 515 500 29 2128801315
LT 2016 154 0 5LITHUANIA 0 55 011 011 5 43 43 0 015400
LV 2016LATVIA
MT 2016 0 0 0MALTA 0 00 00 00 0 0 0 0 0000
NL 2016 986 0 39NETHERLANDS 0 3039 0131 0123 30 310 308 69 69342548
PL 2016POLAND
PT 2016 2 0 51PORTUGAL 0 5749 017 017 55 11 11 4 32373393
RO 2016 146 0 9ROMANIA 0 59 022 021 5 28 28 0 014700
SE 2016 533 0 23SWEDEN 0 3123 077 066 31 144 138 8 856422
SI 2016 0SLOVENIA 0 015 0 26 0860
SK 2016 103 0 2SLOVAKIA 0 52 129 128 5 41 38 0 013300
UK 2016UNITED KINGDOM
Total year 2016 17901 8571 1 0 1092 708 3104 1614 906 615 438811 103247305217432 397
OTHER COUNTRIES
MD 2016 0 0 0MOLDOVA 0 00 00 00 0 0 0 0 0000
NO 2016 94NORWAY 334 4 33 39 39 1 1102
Total year 2016 102 94 0 0 0 0 4 4 33 33 390 113900 0
Section 4: Transplant Centers Page 2 of 3Empty fields: The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Eurocet RegistrySection 4: Transplant Centers
HPC Transplantation
Autologous
Year
3 - OTHER PROCEDURE associated with HPC transplantation*
Allogenic
UnrelatedRelated
N° of
procedures
N° of
Recipients
N° of
procedures
N° of
Recipients
N° of
procedures
N° of
Recipients
MEMBER STATES OF EU
BG 2016 00 0 0BULGARIA 00
CY 2016 20 0 2CYPRUS 00
DE 2016GERMANY
EE 2016ESTONIA
FI 2016FINLAND
HR 2016 63 8 17CROATIA 126
HU 2016HUNGARY
IT 2016ITALY
LT 2016LITHUANIA
LV 2016LATVIA
MT 2016 00 0 0MALTA 00
NL 2016 16139 63 229NETHERLANDS 6457
PT 2016 20 8 3PORTUGAL 130
RO 2016 10 6 1ROMANIA 50
SE 2016 494 12 83SWEDEN 254
SI 2016SLOVENIA
SK 2016 160 13 155SLOVAKIA 1050
UK 2016 385UNITED KINGDOM 340128
Total year 2016 237564 110 87546195
OTHER COUNTRIES
MD 2016 00 0 0MOLDOVA 00
NO 2016 22 2NORWAY 4
Total year 2016 24 2 200
* Donor lymphocyte infusion, Cytokine activated killer cells infusion, other...
Section 4: Transplant Centers
Empty fields:
The corresponding activity is present in the country but the CA does not collect the data yet or has no information on its practice
Page 3 of 3
European Network of Competent Authorities for Tissues and Cells
Appendix I
List of countries and Competent Authorities providing data in 2017
Austria Österreichische Agentur für Gesundheit und Ernährungssicherheit (AGES) – (Austrian Agency for Health and Food Safety)
Belgium
Bulgaria ИЗПЪЛНИТЕЛНА АГЕНЦИЯ ПО ТРАНСПЛАНТАЦИЯ (BEAT) (Bulgarian Executive Agency for Transplantation)
Croatia Ministarstvo zdravstva Zavod za transplantaciju i biomedicine Služba za transplantaciju (Ministry of Health and Social Welfare)
Cyprus Υπουργείο Υγείας της Κυπριακής Δημοκρατίας (MOH) (Ministry of Health of Republic of Cyprus)
Czech Republic Ministerstvo zdravotnictví České republiky (MZCR) (Ministry of Health of the Czech Republic)
Denmark
Estonia Ravimiamet (Estonian State Agency of Medicines)
Finland Lääkealan turvallisuus‐ ja kehittämiskeskus (FIMEA) (Finnish Medicines Agency)
France Agence de la biomédicine (ABM) (French Biomedicine Agency)
Germany Paul‐Ehrlich‐Institut (PEI) (Division of Medical Biotechnology)
Greece
Hungary Állami Népegészségügyi és Tisztiorvosi Szolgálat ‐ Ministry of Human Capacities
Ireland
Italy Centro Nazionale Trapianti (CNT) (Italian National Transplant Centre)
Latvia Zāļu valsts aģentūra ‐ State Agency of Medicines of the Republic of Latvia
Lithuania Nacionalinis Transplantacijos Biuras (NTB) (National Transplant Bureau)
European Network of Competent Authorities for Tissues and Cells
Luxembourg
Macedonia
Malta Ministry of Health (MOH)
Moldova AT ‐ (The Transplant Agency)
Netherlands Miniserie van Volksgezondheid, Welzijn en Sport (Ministry of Health, Welfare and Sport)
Norway Helsedirektoratet (HDIR) (Norwegian Directorate of Health)
Poland Krajowe Centrum Bankowania Tkanek I Komrek (KCBTiK)( National Centre of Tissue and Cell Banking)
Portugal Instituto Português do Sangue e da Transplantação (IPST) (Institute for Blood and Transplantation Services)
Direção‐Geral da Saúde (DGS) (Directorate‐General of Health)
Romania Agentia Nationãla de Transplant (ANT) (National Transplant Agency)
Slovakia Ministerestvo zdravotnictva Slovenskej republiky (NTO)(National Transplant Organisation)
Slovenia Slovenija Transplant
Spain Organización Nacional de Trasplantes (ONT) (National Transplant Organization)
Sweden Health and Social Care Inspectorate (IVO)
Switzerland
Turkey
United Kingdom Human Tissue Authority (HTA)
European Network of Competent Authorities for Tissues and Cells
Appendix II
Glossary A
Allogeneic use: cells removed from one person and applied to another.
Autologous use: cells removed from and applied in the same person.
B
Banking: Processing, preservation, storage and distribution of cells for human application or other purposes, including research and training.
Bone Marrow: Tissue at the centre of large bones. It is the place where new blood cells are produced. Bone
marrow contains two types of stem cell: haematopoietic (which can produce blood cells) and stromal
(which can produce fat, cartilage and bone). In this collection: as a source of hematopoietic stem cells or
mesenchymal stem cells.
C
Cells: means individual human cells or a collection of human cells when not bound by any form of
connective tissue.
Collection: any procedure for procuring a cellular therapy product regardless of technique or source
(Synonym: harvest).
Competent Authority (or Health Authority/Regulatory Authority/Regulatory Agency): the body which has
been delegated with the responsibility for ensuring that tissue and cell donation, banking and human
application are appropriately promoted, regulated and monitored in the interests of donor and patient
safety and public transparency on a national or regional basis by their government.
Cord Blood: Blood collected from placental vessels and umbilical cord blood vessels after the umbilical cord is clamped and/or severed as a source of haematopoietic progenitor cells. Cord Blood Bank: A specific type of tissue establishment in which haematopoietic progenitor cells collected from placental and umbilical cord blood vessels are processed, cryopreserved and stored. It may also be responsible for collection, testing or distribution.
D
Donation: donating human tissues or cells intended for human applications. Donor centre: The organization responsible for recruiting, consenting, counseling and coordinating the testing of prospective donors. Donor: Every human source, whether living or deceased of human cells.
Donor Registry: A registry is an organisation responsible for coordination of the search for Haematopoietic Progenitor Cells (HPC) from donors (including cord blood) unrelated to the potential recipient.
European Network of Competent Authorities for Tissues and Cells
E
Export: Act of transporting a tissue or cell intended for human application to another country where it is to
be processed further or used directly.
H
HLA typing: Tests performed to identify the genetic characteristics of the Human Leukocyte Antigen (HLA) system. Hematopoietic Progenitor Cells (HPC): Primitive haematopoietic cells capable of self‐renewal as well as maturation into any of the haematopoietic lineages, including committed and lineage‐restricted progenitor cells, unless otherwise specified and regardless of tissue source. Also referred to as ‘haematopoietic stem cells.
Human Application: The use of tissues or cells on or in a human recipient.
Human tissues and cells for human application: Material containing or consisting of human tissues and/or
cells intended for implantation, transplantation, infusion, or transfer into a human recipient.
I
Import: The act of bringing tissues or cells into one country from another for the purpose of human
application or further processing.
N
Number of cells discarded: The number of cells that have been discarded.
Number of cells distributed: the total number transported or delivered to a clinical unit (as Article 3 (k) of Directive 2004/23/EC defines. Distribution: “means transportation and delivery of tissues or cells intended for human applications” (Article 3 (k) Directive 2004/23/EC), whereas ‘human application’ is defined in the same article as follows: "means the use of tissues or cells on or in a human recipient and extracorporeal applications’.)
Number of cells stored: number of cells stored. Storage: maintain the product under appropriate controlled conditions until distribution.
O
Organisation responsible for human application: means a healthcare establishment or a unit of a hospital or another body which carries out human application of human tissues and cells
P
Peripheral Blood: in this collection: HSC hematopoietic stem cells collected in peripheral blood by
apheresis.
European Network of Competent Authorities for Tissues and Cells
Potential donor: Any person who has no medical contraindications for organ, tissue or cell donation and who meets the definition of a deceased heartbeating donor, deceased non‐heartbeating donor or living donor. Procurement organisation: means a health care establishment or a unit of a hospital or another body that
undertakes the procurement of human tissues and cells and that may not be accredited, designated,
authorised or licensed as a tissue establishment.
R
Recipient: Person to whom human tissues, cells or reproductive cells and embryos are applied.
Related: Existence of a genetic relationship between donor and recipient.
S
Search Performed: Number of searches for compatibility performed in the marrow registry.
T
Transplantation/implantation/grafting: Transfer (engraftment) of human tissues or cells from a donor to a
recipient with the aim of restoring function(s) in the body.
Transplant Centre: See Organisation responsible for human application.
U
Unique donation number: The unique number attributed to a specific donation of tissues and cells in line
with the system in place in each Member State for allocating such numbers, as further specified in Annex
VII to Commission Directive (EU) 2015/565.
Unrelated: Where there exists no genetic relationship between donor and recipient.