how to select medical journal
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How to select
medical journal?Surat Tanprawate, MD, MSc(Lond.), FRCPT
Division of Neurology, Department of MedicineChaing Mai University
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The failure of common
sense
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The failure of common
sense I shake a tree, an apple falls out, now I
can eat
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The failure of common
sense I shake a tree, an apple falls out, now I
can eat
I give antibiotics for sinusitis, the patientgets better, Im doing a good job as adoctor
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The failure of common
sense I shake a tree, an apple falls out, now I
can eat
I give antibiotics for sinusitis, the patientgets better, Im doing a good job as adoctor
I just saw a patient with tumor lysissyndrome, I will start looking for it moreand maybe Ill nd it more
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Where is the wisdom we have lost
in knowledge,
and the knowledge we have lost in
information?Tuesday, 31 May 2011
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Three levels of reading
1. Browsing , in which we flick through books and journalslooking for anything that might interest us.
2. Reading for information , in which we approach theliterature looking for answers to a specific question, usuallyrelated to a problem we have met in real life.
3. Reading for research , in which we seek to gain acomprehensive view of the existing state of knowledge,ignorance, and uncertainty in a defined area.
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WFME Global Standards
for PG Medical Education Basic Standard
The trainee must become familiarwith EBM and critical clinical decisionmaking
Quality Development The trainee should have formal teachingabout critical appraisal of literature,scientic data and EBM
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Essential step
1. Patient problem
2. Clinical question3. Search for evidence
4. Critical appraisal of the evidence5. Apply the results
Sackett DL, Haynes B. Evidence based Medicine 1995; 1 : 45.
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Before we start:formulate the problem
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Forming a searchable public
health question The PICO framework used in evidence-
based medicine can also be used to create
a searchable question in public health P Patient, population, problem I Intervention (program or treatment
or screening test)
C Comparison (if any)
O Outcome
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Search of evidence
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Every day
the results of ~ 46 randomised clinical trials arepublished
~ 1000 new Medline articles
~ 6,000 new articles in biomedical journals
Every year
~ 3 million articles published in ~ 30,000 journals
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Not all of this information is valid or usefulfor patient care
a little more than 1% is both rigorous andclinically relevant
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Source of information
Primary: searches of journal databases:Medline, Psychinfo
Secondary: Cochrane, Bandolier, ClinicalEvidence
National Electronic Library for Health
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Primary Journal Database
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Secondary Journal Database
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EBM DatabasesEvidence Based Medicine Reviews
(EBMR)-Commercially available thru OVID-Searches a variety of databases
Cochrane Database of Systematic ReviewsACP Journal Club
Medline-Links databases together
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PubMed Search ConsolidationSearch Strategy
Selection of search terms Keywords Phrases
Synonyms
Combination of search terms Boolean logic
Application of limits Occurrence of search terms
Title, Title/Abstract, All elds Types of articles Age groups Etc.
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Boolean logic AND : Combines terms to limit your search as both
concepts must be present in all retrieved articles
Example: osteoarthritis AND knee* OR : Widens your search as either term can be presentin all retrieved articles
Example: osteoarthritis OR arthritis
NOT : Limits your search by excluding a concept asone term must be present and the second term mustnot be present
Example: osteoarthritis NOT hip
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Three preliminary questions to get
your bearings Question 1:Why was the study done
and what hypothesis were the authorstesting?
Question 2:What type of study wasdone?
Question 3:Was this design appropriateto the broad eld of research addressed?
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Primary studiesCase studiesExperimentsSurveysClinical Trials
Secondary studiesNonsystema6c reviewsSystema0c reviews
Metaanalyses Guidelines Decision analyses
Economic analyses
Types of paper research evidence
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Choosing a paper
Relevance for the purpose Purpose may be clinical problem-solving;
informing about new treatment ordiagnostic test
Search efciently Recent and best available paper Avoid case reports
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Where do i nd the
information?
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Where do i nd the
information? Title , Abstract or nal paragraph of
the Introduction should clearly state thequestion
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Where do i nd the
information? Title , Abstract or nal paragraph of
the Introduction should clearly state thequestion
If you still cannot ascertain what thefocused question is after reading thesesections, search for another paper
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ABSTRACTShould I Spend My Time
Reading This Paper ?
States the Purpose of Article, Major Proceduresand Methods, Main Findings, and Conclusions
More and More Journals are usingStructured Abstracts
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Avoid ! The study did not examine an important scientic
issue
The study was not original that is, someone else hasalready done the same or a similar study
The study did not actually test the authorshypothesis
A different study design should have been used Practical difculties (for example, in recruiting
subjects) led the authors to compromise on theoriginal study protocol
The sample size was too smallTuesday, 31 May 2011
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Avoid ! The study was uncontrolled or inadequately controlled The statistical analysis was incorrect or inappropriate
The authors have drawn unjustied conclusions fromtheir data
There is a considerable conict of interest (forexample, one of the authors or a sponsor might benetnancially from the publication of the paper andinsufcient safeguards were seen to be in place toguard against bias)
The paper is so badly written that it isincomprehensible
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Essential step
1. Patient problem
2. Clinical question3. Search for evidence
4. Critical appraisal of the evidence5. Apply the results
Sackett DL, Haynes B. Evidence based Medicine 1995; 1 : 45.
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Case scenario
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A case scenario
A 60-year old patient, known hypertensive,presents with sudden onset headache,vomiting, left hemiplegia and alteredconsciousness starting 3 hours ago
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CT Scan
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Patient problem
Intracerebral hemorrhage with cerebraledema
Clinical question
Surgical role
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Surgery of ICH
Cerebellar: >3 cm in diameter andaltered sensorium
Hydrocephalus: External drainage Supratentorial
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Supratentorial ICH
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Prasad K et al.Surgery for primary supratentorial intracerebral haemorrhage. Cochrane Database of Systematic Reviews 2008, Issue 4. Art. No.:CD000200. DOI: 10.1002/14651858.CD000200.pub2.
Prasad K et al.Surgery for primary supratentorial intracerebral haemorrhage.Cochrane Database of Systematic Reviews 2008, Issue 4. Art. No.:CD000200. DOI: 10.1002/14651858.CD000200.pub2.
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Prasad K et al.Surgery for primary supratentorial intracerebral haemorrhage.Cochrane Database of Systematic Reviews 2008, Issue 4. Art. No.:
CD000200. DOI: 10.1002/14651858.CD000200.pub2.
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Neurology Medicine
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eu o ogy Medicine
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Greenhalgh T. How to Read a Paper:The Basics of Evidence-basedMedicine. London; BMJ; 2006.Clear and concise. Book based on aseries of papers published in theBritish Medical Journal (see courseweb page for PDFs)
Elwood MJ. Critical Appraisal ofEpidemiological Studies andClinical Trials. London; OxfordUniversity Press; 2007.Thorough coverage of epidemiologicalprinciples as well as providing a niceapproach for critical appraisal.One of the best epi books ever written.
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Thank you for your
attention
My Deepest Gratitude to Dr. Siwaporn Chankrachang