how to increase your success in horizon 2020?
TRANSCRIPT
• Webinar• Opportunities for orphan drug
development in Horizon 2020© ttopstart [email protected]
How to increase your success in Horizon 2020?
Horizon 2020
Jasper Levink – partner @ ttopstart
45,000hours wasted
100 scientists together waste up to 45,000 hours each year on unsuccesful grants
FP7 Horizon 20200%
2%
4%
6%
8%
10%
12%
14%
16%
18%
20%
A priori success rates
20%
12%
FFWDFIT – FRAMEWORK – WRITE - DEVELOP
50%ttopstart success rate
It is our mission to empowerresearchers and entrepreneursto drive biomedical innovation
> € 10 million in fundingMultiple business plans
Project management
• • •
ttopstartHorizon 2020
Ir. Jasper LevinkPartner
Sanne Kuijper PhDConsultant
Anouk IJlstOffice manager
Marije aan den Toorn PhDConsultant
Ferdinand Los PhDConsultant
Andree Schram PhDConsultant
Antoinde Weijer PhDConsultant
Patrick de Boer MSc.Co-founder and partner
Karin Bosch – ElbersePhDEU Project Manager
Karlijn Bastiaansen PhDConsultant
Jean-Pierre Sommeijer PhDConsultant
Michelle van Wijk MSc.Consultant
Jochem Bossenbroek MSc.Co-founder and partner
Georgia Xouri PhDConsultant
Jelle Zijlstra MScAnalyst
Horizon 2020 – Work programme 2016 - 2017
• ERC Grants• FET – OPEN• Personalised Medicine
• -Omics• Diagnostics• Therapies• Rare Diseases
• Nanotechnologies• IMI• And much more ….
Each year an estimated € 2.5 billion is allocated for life sciences research
Horizon 2020
Horizon 2020 – trends
Trends:• Increased competition (as low as 10% a priori
success rate)• Focus on translation and commercialisation• Multidisciplinary teams and public-private
partnerships are the standard• Many programmes where industry is in the lead
Horizon 2020
So, but how do I get a ~50% success rate in Europe?
FFWDFIT – FRAMEWORK – WRITE - DEVELOP
FIT
FFWD: FIT – FRAMEWORK – WRITE – DEVELOP
• Excellence• Impact• Implementation
Do you have the plan and people to score the very highest on each of these criteria?
Evaluation criteriaHorizon 2020
FITHorizon 2020
Consortium
Plan
Call
Horizon 2020 call: Understanding disease: systems medicine (PHC-02)
• Consortium: 9 partners (2 hospitals, 3 universities, EMBL and 3 companies)
• Combination of clinical studies, animal models, omics, biomarkers, systems modelling
• Strong group of various disciplines• Frontrunners in the field• Participation of SMEs and mid-sized companies for further
development and commercialisation
Consortium exampleHorizon 2020
Key message: collaboration with industry is essential to be successful in acquiring funding.
FITHorizon 2020
Consortium
Plan
Call
Technology readinessHorizon 2020
Some tips:• Do not fall in love with your ideas and friends• Browse granted projects• Browse our subsidy database
FITHorizon 2020
The most comprehensive life sciences funding database:
www.ttopstart.com/subsidies/database
FRAMEWORK
FFWD: FIT – FRAMEWORK – WRITE – DEVELOP
Research challenge Your solution
ImpactGlobal problem
Research challenge Your solution
ImpactGlobal problem
12% success rate FFWD
50% success rate45.000 hours wasted
Research challenge Your solution
ImpactGlobal problem
Poor preclinical predictive power Organoids
Lower attrition rateHigh pharma development costs
Solution
Minto’s Pyramid principle
Argu
men
t 1
Argu
men
t 2
Argu
men
t 3
Subargument1
Subargument2
Subargument3
Subargument1
Subargument2
Subargument3
Subargument1
Subargument2
Subargument3
Organoids
Minto’s Pyramid principleexample
Pred
icti
ve
Scal
able
Dis
ease
mod
els
Cell-signaling
Cell-interaction
Preliminary data
Subargument1
Subargument2
Subargument3
Subargument1
Subargument2
Subargument3
Some tips:• Keep it simple• Ensure you can tell your complete story in 1 page
+ an illustration• Be ambitious but de-risk• No ‘fishing expeditions’
FRAMEWORKHorizon 2020
WRITE
FFWD: FIT – FRAMEWORK – WRITE – DEVELOP
Some tips:• Keep it simple• Be coherent and consistent• Facilitate ‘vertical reading’ (headings tell the
story)• Use proper English• Be graphical
WRITEHorizon 2020
DEVELOP
FFWD: FIT – FRAMEWORK – WRITE – DEVELOP
Research challenge Your solution
ImpactGlobal problem
Short-term impact Mid-term impact Long-term impact
Scientific
Clinical
Industrial
Societal
Short-term impact Mid-term impact Long-term impact
Scientific
Clinical
Industrial
Societal
Not only what, but also how much and how?
Some tips:• Think big• Quantify• Stakeholder involvement• Support letters• Clear route-to-market strategy• Is take-up beyond project guaranteed?
DEVELOPHorizon 2020
THE PROCESS
FFWD: FIT – FRAMEWORK – WRITE – DEVELOP
Some tips:• Install a small writing team that can write 95% of
the grant• Focus• Ensure you have time to ‘take a step back’
The processHorizon 2020
ttopstart strategic service – PRO-ACTIVHorizon 2020
Valuation
Training & Implementation
Customised funding strategy
AnalysisA
C
T I
V
BEYOND HORIZON 2020
Horizon 2020
Other international programmes
• Wellcome Trust• NIH• Leducq• Human Frontier Science Program• And many more…
www.ttopstart.com/subsidies/database
Horizon 2020
VISIT OUR BOOTH!
ttopstart
You can find us at booth F1.1!
ttopstart [email protected]
P.C. Staalweg 303721 TJ BilthovenThe Netherlands+31 (0)30 73 70 779
Our services• Subsidies• Business development• Project managementFor life sciences and medical
technology
The ttopstart team:Patrick de Boer, MScJochem Bossenbroek, MScir. Jasper LevinkSanne Kuijper, PhDMarije aan den Toorn, PhDFerdinand Los, PhDJean-Pierre Sommeijer, PhDMichelle van Wijk, MScAndrée Schram, PhDGeorgia Xouri, PhDAntoin de Weijer, PhDKarlijn Bastiaansen, PhDKarin Bosch-Elberse, PhDJelle Zijlstra, MScAnouk IJlst, MA
You can find us at booth F1.1!