histology week 10- reproductive system

8/11/2019 Histology Week 10- Reproductive System

1/37

Week 10

Reproductive System


2/37


3/37

Connective tissue capsule


4/37

#2

#3

#1


5/37

TESTIS

Interstitial CT btwseminiferous tubules


6/37

#1

#2

#4

#5

#extracredit


7/37

SEMINIFEROUS TUBULES

Spermatogonia along outer periphery, near basement membrane of tubule Spermatocyte contains nuclei w/ chromosome (primary/secondary) Spermatids small, round; near lumen Sertoli Cells elongated cells; btw spermatocytes


8/37


9/37

SEMINIFEROUS TUBULES** Not pictured is Spermatozoan = small, pointed, nuclei and flagella


10/37

STAGES OF SPERMATOGENESIS


11/37


12/37

OVARY (panoramic view)

Simple cuboidal cells

CT capsule

Large oocyte w/ 1 or 2layers of surroundingcuboidal follicular cells

Variably sizedfollicles; regressionstage; some decayingoocytes inside

Chambercontains follicularfluid

Sheath/capsulebeyond follicularcells

Large, pale CT tissuescar; remnants ofcorpus luteum

Large, pale CT tissuescar; remnants ofcorpus luteum


13/37

#1

#2

#3

#4

#5

#6


14/37

Primordial & Primary follicles


15/37


16/37

Secondary follicles (growing, antral)


17/37


18/37

Tertiary follicle (mature, Graafian)


19/37


20/37

Corpus Luteum


21/37


22/37

Corpus Albicans


23/37

Oviduct (Fallopian or uterine tube)


24/37

Oviduct (Fallopian or uterine tube)


25/37

#2

#1

#3

#4


26/37

UTERUS


27/37

#1

#2

#3

#4

# What is this?


28/37

UTERUS - EndometriumEndometrium = mucosa

Stratum Functionale = nearluminal surfaceThickens and sloughs away duringmensturation

Stratum Basale = neartransition to myometriumRemains after menstruation to regrow intonew stratum functionale

Simple columnar formedinto tubular glands


29/37

PATHOLOGY

WEEK 10HYPERPLASIA ENDOMETRIAL

HYPERTROPHY OF MYOMETRIUM


30/37

HYPERPLASIA

Increase in number of cellsin an organ or tissue increased MASS/SIZE of the organ

Physiologic or Pathologic

Pathologic usually caused by excess hormones on target cell: Example endometrial hyperplasia is due to abnormal increased unopposed estrogen


31/37

NORMAL ENDOMETRIUM


32/37

ENDOMETRIAL HYPERPLASIA


33/37

HYPERTROPHY Increase in cell size increase organ size

Hypertrophied larger cells;

Organ has no new cells Increased size of the cells is due to the synthesis of more structural

components of the cells.


34/37

HYPERTROPHY

Gross appearance of a normaluterus (right) and a graviduterus(removed for postpartumbleeding) (left)


35/37

GRAVID UTERUS(to show wall thickness)


36/37

NORMAL MYOMETRIUM

Small spindle-shaped

uterine smooth musclecells from a normaluterus.


37/37

HYPERTROPHY

large plump cells from the

gravid uterus,same magnification asnormal (in previous slide)

histology week 10- reproductive system

Documents