8/3/2019 Histamine 2

1/14

8/3/2019 Histamine 2

2/14

O %089,230-4.07889,23070.059478,39,43898 ,70545:,7

/7:8:80/390970,9203941,897.

,3//:4/03,:.078O 89,230-4.078570;039,./701:

3900845,:8701:0845,98

O

98,84:80/,890/7:89,9-4.90,.9434189,230435,709,.08

3908942,.

8/3/2019 Histamine 2

3/14

3989,23083989,2308O &80/94970,9,07..43/9438,.9

,,38989,230

8/3/2019 Histamine 2

4/14

$/00110.98,/;0780$/00110.98,/;078070,.9434170,.94341

O 0,/,.0

O 3088

O 43895,943O !7:79:8

O $37,8

O 30.42,89,O 0.70,80/-/4

O 254903.0

8/3/2019 Histamine 2

5/14

O 209/309,,209

3974/:.0/3

.209/30 .,8,8479,110,3/,

8479/:7,94341,.94389-4.8,-4:9

41,./80.7094381474:78

44//301:3.943830.088,7-0.,:80,55742,90944190/7:

0.7090/390:730

%700-4.078

O #,39/30,39,.

O ,249/30505./

O ,9/30,/

8/3/2019 Histamine 2

6/14

7:,3/,-47,9477:,3/,-47,9473907,.94383907,.9438

O 209/30 3907,.9892,3/7:8

3-9305,9./7:209,-4829

03,3.08900110.984147,,39.4,:,398

904530.,11030503943/,393/,05,2;,:257457,344

3/07,5034-,7-9,,3/.,.:2

.,330-4.07

8/3/2019 Histamine 2

7/14

39:.077:84.07839:.077:84.078

0307.7,3/O 209/30 9,,209

O ,249/30 !05./

O ,9/30 /

O #,39/30,39,.

&808,3/.438/07,9438O 475059.:.078,897.,3/

/:4/03,789-4.07

2,7090/,3/7:

3907,.9438/00110.98

O

47970,9203941,.9;0/:4/03,:.073-98,897.

80.709434705490399,3

.209/30

O $,20,81,249,/3084:80/

94970,9,89740845,0,

701:;0 /7:,190720,847

,9-0/920

O %4570;039970,95059.

:.078,89740845,0,

701:897088:.078

8/3/2019 Histamine 2

8/14

!74943!:253-9478,897.!74943!:253-9478,897../$0.709433-9478,897../$0.709433-9478,897../!:253-9478./!:253-9478

O %0!!88:557088,897.,./80.70943-

3-9390/7403549,88:2

,/034830975485,9,800320889024.,90/390,897.5,709,.08%0

903/943-9,897.,./80.70943:594

70,9079,390

-4.07889,230,39,43898

8/3/2019 Histamine 2

9/14

!0583!:253-947:.48,!0583!:253-947:.48,!7490.9;07:!7490.9;07:

O $:.7,1,90 .,7,1,90

8.,8810/,8,505833-947472:.48,

57490.9;0/7:

98,84343,-847-,-0 .42-3089574903941472,;8.4:88:-89,3.09,9

.4;07890:.07,3/57490.9891742,./,3/

50583

98/7:/40834930:97,0/,./47/0.70,80,./80.709438

8/3/2019 Histamine 2

10/14

$:.7,1,90$:.7,1,90O

7:,8839:.07505833-947

O 4397,3/.,9438

50780389;9

O %07,50:9.110.98&808

94570;039,897.2:.48,

3:71742/7:3/:.0/

:.078

O $/0110.98

/30883,:80,

.43895,943/724:97,8

-,.5,380053088

O

7:,-44/3907,.9438

7:/0.70,800110.989

9097,..305039431,9

84:-0;9,238/43

,9070/,-84759439

.57414,.334714,.3

,39,./8

O /;078070,.943

3430831.,39

8/3/2019 Histamine 2

11/14

!7489,,3/33,4:0!7489,,3/33,4:039:.077:39:.077:O 8,/7::80/94570;039,39970,95059.

:.079,550,78948:557088,897.,./

80.70943,3/3.70,80.9457490.9;0 2:.:8

39097,.9O 9.,:808,24/07,90/0.70,80350583

80.70943

O 84574894 8.438/070/,80110.9;0,8

.209/30

8/3/2019 Histamine 2

12/14

39:.077:8!05833-94739:.077:8!05833-947!749435:253-9478,3/!749435:253-9478,3/!7489,,3/339,43898!7489,,3/339,43898

0307.7,3/

O ,38457,40 !70;,./

O 2057,40 57480.

O !,39457,40 574943

&808,3/.438/07,9438

O $4799072970,92039147

/:4/03,:.07,3/0748;0

0845,98&80/3/7:

.42-3,94394970,9547

,840110.9;0147970,93

43070843 83/7420

O %70,9203941#

0845,9843070843

83/7420,3/547

O %70,92039147,897.

/:4/03,:.078#

.9438,20,87,-057,40

8:55708808,897.,./

80.709438

8/3/2019 Histamine 2

13/14

O #,-057,40 .50

O !7489,,3/3,3,4:08

284574894 9490.

O %70,9203941/:4/03,

:.07#

,3/50780.70947 83/74200.70,808,897.,./574/:.943-3-93/7403549,88:2%!,80 0320,9,897.5,709,.08

O !70;0394341$3/:.0/,897.:.07,-09,03/:73$907,53.:/39,8573$%$

&

/,770,,-/423,5,31,9:03.03,:80,;4293.43895,943203897:,854993

8/3/2019 Histamine 2

14/14