hanta-bearing mice: do they diffuse or stay put?
TRANSCRIPT
HantaHanta--bearing mice: do they bearing mice: do they diffuse or stay put?diffuse or stay put?
Guillermo AbramsonCentro Atómico Bariloche and CONICET, Bariloche, Argentina.
Consortium of the Americas for Interdisciplinary Science, University of New Mexico, Albuquerque, USA.
The diffusion paradigm
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IIISI
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SSISS
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MDMMaxKMMMc
ttxM
MDMMaxKMMMcMb
ttxM
∇++−−=∂
∂
∇+−−−=∂
∂
Epidemics of Hantavirus in P. maniculatusAbramson, Kenkre, Parmenter, Yates (2001-2002)
diffusionnonlinear “reaction”(logistic growth)
(Fisher, 1937)uDuurt
txu 2)1(),(∇+−=
∂∂
Wrong but useful: the simplest diffusion models cannot possibly be exactly right for any organism in the real world (because of behavior, environment, etc). But they provide a standardized framework forestimating one of ecology most neglected parameters: the diffusion coefficient.
Not necessarily so wrong: diffusion models are approximations of much more complicated mechanisms, the net displacements being often described by Gaussians.
Woefully wrong: for animals interacting socially, or navigating according to some external cue, or moving towards a particular place.
Three categories of wrongfulnessOkubo & Levin, Diffusion and Ecological Problems
17P
11P
12P
13P
14P
15P
16P
27PA
21P
22P
23PA
24PA
25PA
26PA
37PA
31P
32P
33PA
34PA
35PA
36PA
47B
41B
42B
43B
44B
45B
46B
57B
51B
52B
53B
54B
55B
56B
67B
61B
62B
63B
64B
65B
66B
77B
71B
72B
73B
74B
75B
76B
The source of the dataGerardo Suzán & Erika Marcé, UNM
Six months of field work in Panamá (2003)
Zygodontomys brevicaudaHost of Hantavirus Calabazo
70 m
Zygodontomys brevicauda, 846 captures:
411 total mice, 188 captured more than once (2-10 times)
0.490.370.13Total
0.550.470.00M
0.420.130.22F
ASAJRecapture probability:
Recapture and age
J: juvenileSA: sub-adultA: adultF: femaleM: male
One mouse (SA, F) recaptured off-site, 200 m away
0 20 40 60 80 1000
10
20
30
40
50
60
No.
of m
ice
weight (g)
Female Male
Z. brevicauda - Weight histogramWeight is weight at first capture193 females218 males
0 20 40 60 80 1000.0
0.2
0.4
0.6
0.8
1.0
75 females recaptured113 males recaptured193 females total218 males total
Weight is weight at first capture
Z. brevicauda
Prob
. of r
ecap
ture
weight (g)
Female Male
Recapture and weight
Distribution of weight
-20 -10 0 10 20 30 40 50 60 70-10
0102030405060708090
100
dt (d
ays)
dr (m)
(Overlapped points plotted offset)Z. brevicauda - 434 recaptures
The recaptures
Different types of movement
Adult mice diffusion within a home range
Sub-adult mice run away to establish
a home range
Juvenile mice excursions from nest
Males and females…
0 30 60 90 120-60-50-40-30-20-10
0102030405060 Z. brevicauda captured ~10 times
x(t)
(m)
t (days)
A117008 A117039 A117075 A117104 A117281
Individual mouse walks
0 30 60 90 1200
200
400
600
800
1000
1200
<x2 >
t (days)
008 039 075 104 281 average
Z. brevicauda captured ~10 times
“Mean” square displacement?
-80 -60 -40 -20 0 20 40 60 800
20
40
60
80
100
120
140
160
P(dx
), P(
dy)
dx, dy (m)
dx dy Gaussian fit Lorentzian fit
Z. brevicauda, all sites, 434 recaptures
<dx> = -0.88 mσ2
x = 18.7 m2
<dy> = 1.2 mσ2
y = 20.5 m2
PDF of individual displacementsThe population as an ensemble of walkers
-80 -60 -40 -20 0 20 40 60 80-0.05
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35P(
dx)
dx
dt ~ 1day dt ~ 1 month dt ~ 2 months
247 steps170 steps17 steps
Z. brevicauda
PDF of individual displacementsAs three ensembles, at three time scales
An ensemble of displacements
An ensemble of displacements
An ensemble of displacements…representing the walk of an “ideal mouse”
0 90 180 2700
5x104
1x105
2x105
2x105
x2
t
Average Linear fit
slope = 686 m2/dD
1 = 342 m2/d
Z. brevicauda - 1-day steps
Ideal mouse walks
0 730 1460 2190 2920 3650 4380 51100
1x104
2x104
3x104
4x104
5x104
6x104
7x104
Z. brevicauda - 1-month steps
x2
t
Average Linear fit
slope = 11 m2/dD30 = 6.5 m2/d
Ideal mouse walks
0 365 7300
1000
2000
3000
4000
5000
6000Z. brevicauda - 2-months steps
x2
t
Average Linear fit
slope = 1.9 m2/dD60 = 0.95 m2/d
Ideal mouse walks
0 10 20 30 40 50 60 70 800
500
1000
1500
2000
2500
3000Z. brevicauda - Diffusion properties
x2 (t)
t
b(1-e-at) D1
D30
D60
a = 0.136655 db = 2869.114 m2
D0 ~ 392 m2/dLD ~ 30 m/dHR ~ 54 m
Mean square displacement
(just an ansatz)
“microscopic”diffusion
home range
“microscopic”diffusion length
In summary
Mouse “transport” is more complex than diffusion
Different subpopulations with different mechanisms
Limited data sets can be used to derive some statistically sensible parameters
Existence of home rangesExistence of “transient” mice
Possibility of analytical models
Analysis of other systems (New Mexico…)
0 30 60 90 120-60-50-40-30-20-10
0102030405060
y(t)
(m)
t (days)
A117008 A117039 A117075 A117104 A117281
Z. brevicauda captured ~10 times
Zygodontomys brevicauda
846 captures:
411 total mice, 188 captured more than once (2-10 times)
2231773115Total
10579188M
11898137F
TotalASAJ
Captured once:
188168182Total
11397160M
757122F
TotalASAJ
Recaptured: