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Givaudan Product Catalogue 2017

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Givaudan Product Catalogue 2017

A N T I - A G I N G

COSMOS approved potentially NaTrue China approved

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

BLURHD CQ U/A ()

Dipropylene Glycol (and) Gardenia Florida Fruit Extract

Oxygen Radical Absorbance Capacity (ORAC), Stimulation of BCL2-gene ex-pression limiting apoptosis, Stimulation of Ceramide synthesis (ex-vivo)

Anti-wrinkle effect on crow’s feet (4 %, D28), Smoothing of cutaneous relief and anti-wrinkle effect (2 %, D56)

None 0.1 - 4 %

Hydrosoluble Reduces crow’s feet wrinkles, Stimulates the ceramide synthesis, Smoothes the skin

COSTALANE()

Caprylic/Capric Triglyceride (and) Skeletonema Costatum Extract

Increase of GAP junction number, Promotes epidermal differentiation by increase of connexin 43 level

None 0.1 - 0.3 %

Liposoluble Poly-unsaturated fatty acid rich in omega-3, Restoration of skin homeostasis

EASYLIANCE()China approved version available (Easyliance 2.0)

Acacia Senegal Gum (and) Hydrolyzed Rhizobian Gum

Immediate wrinkle reduction (3 %, 5min)

None 2 - 3 % Hydrosoluble Smoothing, Improvement of micro- relief, Immediate anti-wrinkle

ELLAGI-C()

Propanediol (and) Anogeissus Leiocarpa Bark Extract

Stimulation of vitamin C incorporation, Anti-MMPs properties, Antioxidant activity

Decrease of wrinkle depth (2 %, D14)

None 1 - 2 % Hydrosoluble Anti-aging, Anti-wrinkle

HYDREIS()

Aqua (and) Hydrolyzed Beta-Glucan (and) Sodium Benzoate (and) Potassium Sorbate (and) Citric Acid

Stimulation of the synthesis of filaggrin, Stimulation of the synthesis of aquaporin, Restoration of the skin‘s structure and water homeostasis (ex-vivo), Restoration of the skin‘s structure with filaggrin (ex-vivo), Restoration of hydric homeostasis with AQP-3 (ex-vivo)

Reparative effect on the barrier function (1 %, D3)

Sodium benzoate, Potassium sorbate

1 % Hydrosoluble 3- in-1 active for skin rehydration, restructure and repair

HYALUSPHERE PF ()

Spherulites®

Aqua (and) Sucrose Palmitate (and) Tocopheryl Acetate (and) Glyceryl Linoleate (and) Sodium Hyaluronate (and) Phenoxyethanol (and) Potassium Sorbate (and) Citric Acid

Penetration test by Raman micro-imaging (ex-vivo), Visualisation of the incorporation of Hyalusphere in emulsions

Decrease of average wrinkle number (3 %, 1h, 6h)

Phenox-yethanol, Potassium sorbate

2 - 3 % Water dispersible

Vectorized (Spherulites technology) hyaluronic acid to recover skin‘s volume and reduce wrinkles in a very short term

HYALUSPHERE XP ()

Spherulites®

Aqua (and) Sucrose Palmitate (and) Tocopheryl Acetate (and) Glyceryl Linoleate (and) Sodium Hyaluronate (and) Benzyl Alcohol (and) Potassium Sorbate (and) Citric Acid

Penetration test by Raman micro-imaging (ex-vivo), Visualisation of the incorporation of Hyalusphere in emulsions

Decrease of average wrinkle number (3 %, 1h, 6h)

Benzyl alcohol, potassium sorbate

2 - 3 % Water dispersible

Vectorized (Spherulites technology) hyaluronic acid to recover skin‘s volume and reduce wrinkles in a very short term

MEGASSANE()

Caprylic/Capric Trigliceride (and) Phaeodactylum Tricornutum (and) Tocopherol

Repairing and protection of proteins from UV damage, revitalization, Detoxification (Lit), Anti-age spots (Lit), DNA repair (Lit)

None 0.1 - 0.3 %

Liposoluble Phytoplancton extract rich in omega-3, Cell protection from UV, Prevention from photo-aging and age-spots

REDENS‘IN()

Spherulites®

Sucrose Palmitate (and) Aqua (and) Caprylic/Capric Triglyceride (and) Glyceryl Linoleate (and) Commiphora Mukul Resin Extract (and) Sodium Hyaluronate (and) Tocopherol (and) Citric Acid (and) Phenoxyethanol (and) Potassium Sorbate

Skin is subject to ECM and adipose tissue age-related alterations (2 %)

Phenoxyeth-anol

1.5 - 2 %

Water dispersible

A dermis and hypodermis voluminizing ingredient and high molecular weight hyaluronic acid encapsulated in Spherulites, Plumping, Anti-wrinkle

2

A N T I - A G I N G

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

REVIVYL(Cosmos certification on-going)

Propanediol (and) Orobanche Rapum Extract

Maintaining of the capability of skin stem cells to replicate themselves, Increase of expression of survivin after UV exposure, Inhibition of caspase 9 and caspase 3, Stimulation of epidermis metabolism (ex-vivo), Stimulation of keratinocytes differentiation and barrier function, Improvement of epidermal differentiation and barrier function (ex-vivo), Stimulation of the skin barrier components production (ex-vivo), Biological reactivation of natural exfoliation (ex-vivo)

Skin barrier reinforcement and hydration (Raman), (0.5 %, D14, D28), Skin epidermis restructuration (OCT), (0.5 %, D14, D28), Increase of skin surface renewal, exfoliation (Diagnoskin), (0.5 %, D7, D28), Maintenance of the stratum microbium (0.5 %, D14), Anti-aging effect (crow’s feet wrinkles), (0.5 %, D28)

None 01 - 0.5 %

Hydrosoluble Holistic skin renewal accelerator

SOFTALIA CQ U/A

Fusanus Spicatus Kernel Oil Improvement of skin condition on face (reduction in lines, More moist/supple, Reduction in flakiness), Neck (Skin tightness, Reduction in wrinkles/lines, More moist/supple) and hands (much tighter, more moist/supple) (5 %) (Panelist‘s evaluation), Enhancement of sensorial benefits of cream formulation (2 %)

None 0.5 - 5 %

Liposoluble Sustainable Australian sandalwood nut oil, Firm and supple skin, Reduction of fine wrinkles

SPRING SEA WATER()

Maris Aqua (and) Phenoxyethanol

Stimulation of skin lipid synthesis, Dermo epidermal junction reinforcement, Skin moisturisation compared to classic water (ex-vivo)

Phenoxy-ethanol

20 - 100 %

Hydrosoluble Spring sea water enriched in trace elements talcing a unique composition

STIMULHYAL()

Calcium Ketogluconate Elastin synthesis, hyaluronic acid synthesis, increase of hyaluronic acid synthesis (ex-vivo), Interaction with CD 44 (in silico test), Increase in CD 44 by immunolabelling (ex-vivo)

Skin elasticity (0.5 %), Anti-skin fatigue (0.5 %)

None 0.3 - 0.5 %

Hydrosoluble Anti-aging effect by increasing natural production of hyaluronic acid

VITASPHERES E XP()

Aqua (and) Sucrose Palmitate (and) Tocopheryl Acetate (and) Glyceryl Linoleate (and) Benzyl Alcohol (and) Potassium Sorbate (and) Citric Acid

Potassium Sorbate ,Citric acid

5 - 15 % Hydrosoluble Vitamin E encapsulated in Spherulites for improved penetration

3

B O D Y S C U L P T I N G

C O O L I N G / O T H E R S

COSMOS approved potentially NaTrue China approved

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

ABDOLIANCE Sucrose Palmitate (and) Poly-sorbate 20 (and) Glyceryl Linoleate (and) Paullinia Cupana Seed Extract (and) Maltodextrin (and) Prunus Amygdalus Dulcis (Sweet Almond) Oil (and) Lecithin (and) Aqua (and) Citrus Aurantium Amara (Bitter Orange) Peel Extract (and) Phenoxyethanol (and) Tocopherol

Waist size reduction (2 %, D28), Reduction of hypodermis thickness (3 %, D28)

Phenoxy-ethanol

1 - 3 % Water dispersible

Waist slimming for men

ACTISCULPT CQ U/A ()

Dipropylene Glycol (and) Commiphora Mukul Resin Extract (and) Coleus Forskohlii Root Extract

Increase of cAMP level in adipocytes

Thigh reduction and skin surface smoothing (1 %, D28, D56)

None 1 % Liposoluble Herbal firming

AXOLIGHT()

Aqua (and) Triticum Aestivum Extract Inhibition of melanogenesis, Inhibition of melanogenesis via TRP-1 (ex-vivo)

Lightening efficacy on Asian volunteers (3 %, D56)

None 2 - 3 % Liposoluble Whitening, Lightening

BETAPHROLINE()

Aqua (and) Butylene Glycol (and) Tephrosia Purpurea Seed Extract (and) Phenoxyethanol

Stimulation of beta endorphin release, Adenylate cyclase activation, G3PDH inhibition, Glycerol release

Pain release and improvement in the well-being of stomatodynia patients (oral application) (10 %, D30; Panelist’s evaluation)

Phenoxy-ethanol

2 - 8 % Hydrosoluble A „well-being“ provider by means of neurocosmetic and body shaping

COMMIPHERO-LINE()

Caprylic/Capric Triglyceride (and) Commiphora Mukul Resin Extract

G3PDH activation (effects on lipogenesis), cAMP inhibition (effects on lipolysis), Increase of triglyceride quantity in adipocytes

None Anti-aging: 0.2 - 0.6 % Bodycare: 0.5 - 1 %

Liposoluble Skin tonifier, Wrinkle filler, Breast and décolleté care

PRO-DG Aqua (and) Plankton Extract (and) Sodium Benzoate (and) Potassium Sorbate (and) Citric Acid

Inhibition of triglycerides synthesis, Stimulation of cAMP rate, Stimulation of lipolyse (in-vitro & ex-vivo) Reduction of the adipocytesdiameter (ex-vivo)

Reduction of thighs size (3 %) Sodium benzoate, Potassium sorbate

3 % Hydrosoluble Marine origin slimming to reduce the tigh-size

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

DIAMOND()

Diamond Powder Improvement of skin regeneration, stimu-lation of immuno reactions (Lit)

None 0.5 - 2 %

Oil dispersible Stimulates cutaneous microcircu-lation, Improves skin complexion, Energyzing, Granulometry: < 15μ

EVERCOOL SKIN Menthyl PCA (and) Lactamide MEA (and) Menthane Carboxamide Ethylpyridine

Activation of cooling sensation receptor TRMP

Long lasting cooling effect (2 %, 30min, 60min, 120min)

None 1 - 4 % Water and Alcohol soluble

Patented combination of cooling actives, Improved long-lasting freshness, Odourless cooling agent

4

H A I R A N D B O D Y C A R E

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

CERAMIDE II CQ U/A ()

Ceramide NG Deposition onto hair (ex-vivo), Evaluation of hair softness (ex-vivo), Hair strengthening effect (ex-vivo, 1 %)

Reduction of TEWL (2 %, D26)

None 0.05 - 1 %

Liposoluble Skin moisturizer, Lipid barrier rebuilder, Hair strengthener & conditioner

GLOSSYLIANCE()

Aqua (and) Lactic Acid (and) Citrus Limon Peel Extract (and) Saccharum Officinarum Extract (and) Malic Acid (and) Citric Acid

Increased shine (ex-vivo), Increased softness (ex-vivo)

Increased shine(1 / 3 / 5 %), Increased softness (1 / 3 / 5 %, D14)

None 3 % Hydrosoluble Increases hair shine, Visible effect of softness of the hair

HAIRSPHERE AG XP ()

Spherulites®

Aqua (and) Polyglyceryl-3 Distearate (and) Polysorbate 60 (and) Myristic Acid (and) Stearic Acid (and) Palmitic Acid (and) Guar Hydroxypropyltrimonium Chloride (and) Triticum Vulgare Flour Lipids (and) Persea Gratissima Oil (and) Benzyl Alcohol (and) Potassium Sorbate (and) Citric Acid

Benzyl alcohol, Potassium sorbate

0.05 - 3 %

Water dispersible

Vectorized (Spherulites technology) fatty acids, avocado oil and ceramids; an ideal mixture of active ingredients for hair nourishment

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

QUESTICE LIQUID CQ U/A ()

Menthyl PCA Underarm cooling panel test with deodorant spray (1.7 %), Long-lasting effect of Questice vs. Menthol with no burning sensation (1 %), Synergistic effect of Questice Plus with increased initial ‘cooling burst’ (1.2 % Questice® Plus (1 % Questice®)

None 1 - 1.5 %

Water and Alcohol soluble

Long-lasting perception of cooling and additional moisturizing effect

QUESTICE PLUS CQ U/A()

Menthyl PCA (and) Menthol (and) Dipropylene Glycol

Underarm cooling panel test with deodorant spray (1.7 %), Long-lasting effect of Questice® vs. Menthol with no burning sensation (1 %), Synergistic effect of Questice® Plus with increased initial ‘cooling burst’ (1.2 % Questice® Plus (1 % Questice®)

None 1 - 2 % Water and Alcohol soluble

Immediate and long-lasting perception of cooling composed of 1 % Questice Liquid + 0.2 % free Menthol

SOLIGEL()

Rhizobian Gum Immediate reduction of dark rings (2 %), Improvement of sensorial properties of the formula (0.25 %) alone or with salt, Flash moisturizing effect (2 %)

None 0.1 - 2 %

Hydrosoluble Anti-dark circle under the eyes, Anti-redness, Rheology modifier, Improves sensory characteristics of cosmetic formulations

XYLIANCE()

Cetearyl Wheat Straw Glycosides (and) Cetearyl Alcohol

None 2 - 5 % Liposoluble Patented and natural emulsifier for white and unctuous emulsion, High emulsifying capacity for virgin oils and silicons without co-emulsifier, good compatibility with sun care ingredients

5

H A I R A N D B O D Y C A R E

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

RESISTHYAL()

Water (and) Sodium Hyaluronate (and) Hydrolyzed Hyaluronic Acid (and) Phenoxyethanol (and) Lactic Acid

Sheathing effect around hair fibre (ex-vivo), Biological hydration of hair fibre (ex-vivo), Resistance to mechanical and thermal stresses (ex-vivo), Resistance to dullness, increased shininess (ex-vivo), Resistance to frizzing, hair straightening enhancement (ex-vivo), Resistance to pollution, anti-adhesion properties (ex-vivo)

Global hair beauty enhancement in a rinse- off formulation (3 %, D14, D28), “Increased perception of the hair beauty parameters” (shininess, lightness, easiness to comb, natural volume, resistance, revitalise, increased body and matter, smoothesness, softness, suppleness) (1.5 % & 3 %, D28) (panelist’s evaluation), Anti-frizz and resistance to humidity (3%, single use), Beauty enhancement in a rinse-off formulation (1.5 %, 3 %, D28)

Phenoxyeth-anol

1.5 - 3% Hydrosoluble Hair beauty enhancer

SINODOR CQ U/A()

Citronellyl Methylcrotonate Reduction of body all types of body malodours, Reduction of fatty acid malodours of formula bases (1 %), Reduction of odor emitted by permanent waves (ex-vivo, 0.5 %), Reduction of smoke odour on hair (ex-vivo, 0.5 %)

None 0.2 - 1 %

Liposoluble Odour control

SOFTOLIVE()

Hydrogenated Ethylhexyl Olivate (and) Hydrogenated Olive Oil Unsaponifiables

None 2 - 10 % Liposoluble Very dry olive-based emollient, Excellent penetration and skin feel for skin, Sun and hair care

UNIBLEND 2 CQ U/A()

Aqua (and) PEG 7 Glyceryl Cocoate (and) PEG 60 Hydrogenated Castor Oil (and) Ceramide NG (and) Methylchloroisothi-azolinone (and) Methylisothiazolinone

Gluconolac-tone, Sodium benzoate

0.5 - 10 %

Water dispersible

Dispersion of 2 % CERAMIDE II CQ U/A for easier incorporation into formulas, Especially rinse-off, Hair strengthener & conditioner

YOGURTENE BALANCE CQ (PFR) U/A()

Inulin (and) Yogurt Powder Strong reduction of S. aureus and E. coli species present on the skin

None 0.5 -5 %

Prebiotic efficacy, Promotes to balance skin flora by anti-bacterial effect, Skin moisturizing

YOGURTENE CQ (PFR) U/A()

Yogurt Powder Stimulation of collagen latice concentration

Improves quality of dry hair, combability of wet hair and defines curles (0.2 % in combing cream), hair style holding and anti-fly-away (1 %), Perceivable improvement of soap foam density and creaminess (0.5 %)

None 0.5 - 5 %

Hydrosoluble Skin firming properties, Hair conditioner, Lather booster

6

H Y A L U R O N I C A C I D

COSMOS approved potentially NaTrue China approved

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

CRISTALHYAL()

Sodium Hyaluronate Skin moisturisation (Raman Spectroscopy) (ex-vivo), Prevention and calming of inflammation, Protection against UVB

Long-lasting moisturization up to 24 hours (0.1 %, 8h, 24h)

None 0.01 - 0.3 %

Hydrosoluble Moisturization by film forming and water retention, Eye contour care; MW 1-1.4 MDa

PRIMALHYAL 300()

Hydrolyzed Hyaluronic Acid

Increase of beta-defensine release, especially DEFB2 (in-vitro, ex-vivo), Stimulation of DEFB4 gene expression, Inhibition of gram negative bacteria activity (ex-vivo), Stimulation of keratinocytes migration and fibroblasts prolieferation (support of wound healing), Migration and proliferation of the fibroblasts, Penetration in the skin (ex-vivo)

None 0.05 - 0.2 %

Hydrosoluble Hyaluronic acid with mid-range MW 100-300 kDa, Stimulation of the skin natural defense system

PRIMALHYAL 3K()

Hydrolyzed Hyaluronic Acid

Stimulation of tight junction protein synthesis, Stimulation of DEFB2 release (in-vitro & ex-vivo), Antimicrobial activity, Specific healing activity, Stimulation of procollagen I, Improvement of HA synthesis

Improvement of skin biomechanical properties (0.5 % 20-50kDa HA)

None 0.1 - 1 %

Hydrosoluble PrimalHyal 3K is a mix of 3 Hyaluronic Acids (HA): • PrimalHyal 300 (100-300 kDa) to

reinforce the skin natural defense and wound healing process

• PrimalHyal 50 (20-50 kDa) to improve skin biomechanical properties and firmness

• PrimalHyal 20 (5-20 kDa) to rejuvenate the dermis from inside

PRIMALHYAL 50()

Hydrolyzed Hyaluronic Acid

Stimulation of tight junction protein synthesis, Stimulation of procollagen I

Moisturization effect (0.5 %), Skin is more moisturized, skin is more tonic, skin is firmer (0.5 %; Panelist‘s evaluation)

None 0.1 - 0.5 %

Hydrosoluble Hyaluronic acid with very low MW (20-50 kDa), Reduction of TEWL (patent), Collagen-boosting effect, Skin hydro-retention, Improves skin tonicity

PRIMALHYAL GOLD()

PEG-8 Caprylic/Capric Glycerides (and) Water (and) Octyldodeceth-25 (and) Sodium Hyaluronate

Skin penetration (ex-vivo), Instant and long lasting hydration benefits (ex-vivo; total water content T+30min vs T+8h +13 %; +45 % vs T0; free water content T+30min vs T+8h +14 %; +50 % vs T0)

Phenoxyeth-anol, De-cylene glycol, Propylene glycol

4 - 5 % Liposoluble Oilsoluble hyaluronic acid for longterm hydration, make-up care, lip products

RENOVHYAL()

Sodium Hyaluronate Stimulation of tight junction protein synthesis, Stimulation of procollagen I

Moisturization effect (0.5 %), Skin is more moisturized, Skin is more tonic, Skin is firmer (0.5 %; Panelist‘s evaluation)

None 0.1 - 0.5 %

Hydrosoluble Hyaluronic acid with very low MW (20-50 kDa), Reduction of TEWL (patent), Collagen-boosting effect, Skin hydro-retention, Improves skin tonicity

H Y A L U R O N I C A C I D

2‘200

2‘000

1‘800

1‘000

700

500

300

100

1‘400

50

20

5Very low

Low

Average

Very high

High

Cutaneous permeability of HA

Molecular weight kDa Powder form Coupling

PrimalHyal 10<10 kDa

PrimalHyal 20 5 - 20 kDa

PrimalHyal 50 Renovhyal20 - 50 kDa

PrimalHyal 300 Bashyal Powder

100 - 300 kDa

Cristalhyal 1.0PrimalHyal 1000 700 - 1000 kDa

Cristalhyal 1 - 1.4 MDa

Hyalusphere XP & PF

Cristalhyal MW+1.4 - 2 MDa

Cristalhyal 2.21.8 - 2.2 MDa

Hydrolyzed Hyaluronic Acid

> PRIMALHYAL range INCI: Hydrolyzed Hyaluro-

nic Acid

> BASHYAL Powder,RENOVHYAL

INCI: Sodium Hyaluronate

Native Hyaluronic Acid> CRISTALHYAL range INCI: Sodium Hyaluronate

8

S K I N C O M P L E X I O N

COSMOS approved potentially NaTrue China approved

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

HYDRINTENSE()

Maris Aqua (and) Propanediol (and) Porphyridium Cruentum Extract

Increase of skin‘s water content (ex-vivo)

Increase of skin‘s water content upto 24hrs (5 %, 24h), Improvement of the skin microrelief (5 %, D7)

None 3 - 5 % Hydrosoluble Moisture power and improvement of skin microrelief

PORPHYRALINE SP()

Porphyridium Cruentum Extract Increase of epidermal lipid, improvement of the anchoring capacity of basal membrane, increase of beta-1-integrin and alpha-6-integrin

None 3 - 5 % Hydrosoluble Reinforcement of skin‘s self-defense, Film forming effect

LIPSPHERE G PF()

Spherulites®

Glycerin (and) Sucrose Tristearate (and) Aqua (and) Potassium Sorbate (and) Sodium Benzoate (and) Citric Acid

Potassium sorbate, Sodium benzoate, Citric acid

1 - 10 % Liposoluble Vectorized (Spherulites etchnology) glycerine in a lipophilic structure which transformes its affinity with the preparation medium. Lipsphere G PF improves the texture of bases and gives effective moisturizing properties to end products

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

AXOLIGHT()

Aqua (and) Triticum Aestivum Extract Inhibition of melanogenesis, Inhibition of melanogenesis via TRP-1 (ex-vivo)

Lightening efficacy on Asian volunteers (3 %)

None 2 - 3 % Hydrosoluble Whitening, Lightening

SOPHOLIANCE S()

Candida Bombicola/ Glucose / Methyl Rapesee-date Ferment (and) Aqua (and) Potassium Sorbate

Anti-bactericidal activity Regulation of sebum production (2 %), Acne prevention (2 %)

Potassium sorbate

1 - 2 % Hydrosoluble Anti-acne, Anti-lipase, Protection of skin‘s self-defense, Anti-bacterial

VEGETAN()

Dihydroxyacetone Self tanning (5 %) None 1 - 5 % Hydrosoluble Self tanning, Sun care

VEGETAN FL()

Dihydroxyacetone (and) Aqua Self tanning (5 %) None 1 - 8 % Hydrosoluble Self tanning, Sun care

VEGETAN FL CREATION

Dihydroxyacetone (and) Aqua (and) Parfum (and) Polysorabate 20 (and) Caprylyl/ Capryl Wheat Bran/Straw Glycosides

Self tanning (5 % ), Minimization of odour caused by DHA‘s reaction with skin (11 %)

None 2 - 15 % Hydrosoluble Creative solution of DHA with a specific perfume to soften the odour during self tanning

VEGETAN GOLD PEG-8 Caprylic/Capric Glycerides (and) Water (and) Dihydroxyacetone (and) Octyldodeceth 25

Self tanning (30 %, 60 %)

None 30 - 60 % Lipo- and hydrosoluble

DHA for oily formulations for natural looking tan with long-lasting effect

VEGETAN PREMIUM

Dihydroxyacetone (and) Melanin Antioxidant effect Improvement of color intensity and increase of speed of coloration (5 %), Tanning quality (5 %)

None 1 - 5 % Hydrosoluble Self tanning for faster and more intense effect with improved quality

M O I S T U R I Z I N GH Y A L U R O N I C A C I D

9

S K I N P R O T E C T I O N

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

DEPOLLUTINE()

Aqua (and) Arginine PCA (and) Phaeodactylum Tricornutum Extract (and) Phenoxyethanol

Reduction of microinflammation by targeting ICAM-1 (ex-vivo) Prevention from cigarette smoke damage (reduction of leukocyte adhesion)

Phenoxyeth-anol

1 - 3 % Hydrosoluble Limitation of pollution induced damage on skin

GREVILLINE PF()

Glycerin (and) Aqua (and) Skeletonema Costatum Extract (and) Phenoxyethanol

Inhibition of IL-8 release and PLA2 activity

Reduction of UV-induced erythema (3 %, D3)

Phenoxyeth-anol

1 - 3 % Hydrosoluble Peptidic fraction of a phytoplankton, Anti-inflammatory, Anti-redness

KENDI OIL()

Aleurites Moluccanus Seed Oil Subjective sensory assessment in comparison with Argan oil

None up to 100 %

Liposoluble Natural oil rich in omega-3 fatty acids, Rich in natural tocopherol and less sensitive to oxidation, Dry oil with good sensoric properties

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

VEGETAN PREMIUM PLUS()

Dihydroxyacetone (and) Melanin Antioxidant activity Kinetics of skin coloration (5 %, 3h, 6h, 8h)

None 3 - 5 % (self-tanning products) 1 - 2% (Glowing products)

Hydrosoluble Self-tanning, Combination of DHA/Allomelanin like polymer (from caffeic acid polymerisation) for a natural tan, a quick and intense coloration and anti-oxidant activity

WAKAMINE XP()

Aqua (and) Undaria Pinnatifida Extract (and) Benzyl Alcohol (and) Potassium Sorbate

Reduction of skin color, Inhibition of melanin production (ex-vivo)

Comparable lightening effect as 2 % Arbutin (1 % Wakamin XP + 1 % Arbutin)

Benzyl alcohol, Potassium sobrate

1 - 3 % Hydrosoluble Whitening, Lightening

WHITESPHERE PREMIUM()

Spherulites®

Sucrose Palmitate (and) Butylene Glycol (and) Glyceryl Linoleate (and) Prunus Amygdalus Dulcis Oil (and) Aqua (and) Glycyrrhiza Glabra Root Extract (and) Magnesium Ascorbyl Phosphate (and) Undaria Pinnatifida Extract (and) Phenoxyethanol

Inhibition of melanin production of Galabridin (Lit.), Inhibiton of melanin production by Undaria Pinnatifida extract (ex-vivo), Anti-oxidative capacity of ascorbic acid (Lit.), Anti-inflammatory activity of Galabridin (Lit.), Reduction of melanin production (ex-vivo)

Age spot reduction 1 %), Cutaneous aspect is improved, aspects of the age spots are improved, I would buy such a cosmetic product (1 %; Panelist‘s evaluation)

Phenoxyeth-anol

0.5 - 1 % Water dispersible

Synergistic complex of whitening actives encapsulated in Spherulites for improved penetration of the well known whitening actives, Specific treatment against age spots

WHITESPHERE PREMIUM XP()

Spherulites®

Sucrose Palmitate (and) Butylene Glycol (and) Glyceryl Linoleate (and) Prunus Amygdalus Dulcis Oil (and) Aqua (and) Glycyrrhiza Glabra Root Extract (and) Magnesium Ascorbyl Phosphate (and) Undaria Pinnatifida Extract (and) Benzyl Alcohol (and) Potassium Sorbate

Inhibition of melanin production of Galabridin (Lit.), Inhibiton of melanin production by Undaria Pinnatifida extract (ex-vivo), Anti-oxidative capacity of ascorbic acid (Lit.), Anti-inflammatory activity of Galabridin (Lit.), Reduction of melanin production (ex-vivo)

Age spot reduction (1 %), Cutaneous aspect is improved, aspects of the age spots are improved, I would buy such a cosmetic product (1 %; Panelist‘s evaluation)

Benzyl alcohol, Potassium sobrate

0.5 - 1 % Water dispersible

Synergistic complex of whitening actives encapsulated in Spherulites for improved penetration of the well known whitening actives, Specific treatment against age spots

10

Product INCI in-vitro / ex-vivo in-vivo Preserv-atives

Use level Solubility Features

MARILIANCE Aqua (and) Propanediol (and) Rhodosorus Marinus Extract

Reduction of TRPV1 expression, Inhibition of the expression of IL-1α, NRG, NGF R, Reduction of NGF production, Reduction of IL1α synthesis, Penetration of Mariliance in emulsion and validation of the results observed in-vitro on IL-1α production (ex-vivo)

Reduction of skin sensitivity (3 %, D14, D28)

None 1 - 3 % Hydrosoluble Marine neuro-soother

MUCILIANCE FRUIT()

Galactric Acid Chelating effect at wide pH-range

None 0.1 - 0.2 %

Hydrosoluble A powerful chelating agent at a wide range of pH and can replace a number of chelating agents as EDTA or citric acid, Strong anti-oxidant and boosts preservatives

NEUROPHROLINE()

Aqua (and) Propanediol (and) Tephrosia Purpurea Seed Extract

Inhibition of stress hormone cortisol release, Stimulation of β-endorphin production, Global activation of anti-stress genes (transcriptomic on keratonocytes and fibroblasts), Activation of anti-stress proteins HMOX1 and NQO1 (proteomic on keratonocytes and fibroblasts), Increase of HMOX1 and NQO1 expression in epidermis (ex-vivo)

Efficacy on stressed (polluted air) skin: Improvement of skin luminocity, Reduction of skin redness, Improvement of global skin color (2 %, D14/D28)

None 0.1 - 2 % Hydrosoluble Overall skin stress control

NYAMPLUNG OIL()

Calophyllum Inophyllum Seed Oil

SPF boosting, DNA protection from UVA and -B, Anti-oxidation, Cell repair activity after wound

None 1 - 10 % Liposoluble Dry emollient with high content at unsaponifiables and tocotrienol, Production fully ecological

OCALINE PF()

Maris Aqua (and) Aqua (and) Cucurbita Pepo Seed Extract (and) Potassium Sorbate (and) Phenoxyethanol (and) Citric Acid

Inhibition of the mast cells degranulation (ex-vivo)

Preventive effect on sensitive skin/Stinging test (5 %, D14), Soothing of irritated skin (10 %, 60min, 180min, 24h)

Potassium Sorbate, Phenoxyeth-anol

3 - 10 % Hydrosoluble Prevention of sensitive skin by a neurocosmetic approach

OCALINE XP()

Maris Aqua (and) Aqua (and) Cucurbita Pepo Seed Extract (and) Citric Acid (and) Benzyl Alcohol (and) Potassium Sorbate

Inhibition of the mast cells degranulation (ex-vivo)

Preventive effect on sensitive skin/Stinging test (5 %, D14), Soothing of irritated skin (10 %, 60min, 180min, 24h)

Benzyl Alcohol, Potassium Sobrate

3 - 10 % Hydrosoluble Prevention of sensitive skin by a neurocosmetic approach

SOOTHEX CQ U/A()

Dipropylene Glycol (and) Boswellia Serrata Gum

Inhibition of 5-Lipoxygenase Reduction of skiN reddening effect induced by a depilatory cream (2.5 %), Reduction of AHA induced irritation (2 %), Reduction of SLS induced skin irritation (2.5 %)

None 0.5 - 2.5 %

Liposoluble, Hydrosoluble with surfactant

Soothing, Reduction of skin irritation, Suitable for sensitive skin formulations

SOOTHEX ISA CQ U/A()

Isostearyl Alcohol (and) Boswellia Serrata Gum

Inhibition of 5-Lipoxygenase Reduction of skin redde-ning effect induced by a depilatory cream (2.5 %), Reduction of AHA induced irritation (2 %), Reduction of SLS induced skin irritation (2.5 %)

None 0.5 - 2.5 %

Liposoluble, Hydro-soluble with surfactant

Soothing, Reduction of skin irritation, Suitable for sensitive skin formulations

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S P H E R U L I T E S ®Unique encapsulation technology

Our partner Givaudan has developed a patented micro-encapsula-tion system called Spherulites® which, alongside a fascinating suc-cess story, impresses above all for its unique technology.

Spherulites® are multi-layered microspheres of surfactants that can encapsulate both water-soluble and oil-soluble actives, and can therefore serve as transporting agents in cosmetic products. This “encapsulation” technology has interesting auxiliary propeties:

Non-ionic and anionic Spherulites®, for instance, improve penetration into the skin layers, while the cationic varieties improve adhesion on the skin surface. The multi-layered encapsulation can also be exploit-ed to achieve a long-lasting action. Furthermore, Spherulites® allow sensitive actives to be stabilized.

Alongside a standard range, custom solutions can be developed in which several active ingredients are packed together into Spherulites®.

Spherulite® microencapsulation technology

Distributed by IMPAG AG Räffelstrasse 128045 ZürichSwitzerlandPhone: +41 43 499 25 00Fax: +41 43 499 25 01E-Mail: [email protected]: www.impag.ch

IMPAG Group Country OfficesAustria/Vienna – www.impag.atFrance/Nancy – www.impag.frGermany/Offenbach – www.impag.dePoland/Warsaw – www.impag.plSwitzerland/Zurich – www.impag.ch

08/ 2017