genetic map of drosophila
DESCRIPTION
Genetic Map of Drosophila. Fig. 5-14. P. M. Pairing of Homologous Chromosomes. Fig. 2-13, 2-14. Crossing Over Occurs Between DNA of Homologous Chromosomes. Paternal. Paired Homologous Chromosomes. Maternal. Fig. 2-8. Drosophila melanogaster (Fruit Fly). Phenotypes eye color - PowerPoint PPT PresentationTRANSCRIPT
![Page 1: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/1.jpg)
Genetic Map of Drosophila
Fig. 5-14
![Page 2: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/2.jpg)
Pairing of Homologous Chromosomes
P
M
Fig. 2-13, 2-14
![Page 3: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/3.jpg)
![Page 4: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/4.jpg)
Crossing Over Occurs Between DNA of Homologous Chromosomes
Paternal
Maternal
PairedHomologousChromosomes
![Page 5: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/5.jpg)
Fig. 2-8
![Page 6: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/6.jpg)
Drosophila melanogaster (Fruit Fly)
Phenotypes• eye color• body color• wing shape• antenna length• bristle pattern
![Page 7: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/7.jpg)
Single Crossover (SCO)
Paternal
Maternal
PairedHomologousChromosomes
![Page 8: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/8.jpg)
Double Crossover (DCO)
PairedHomologousChromosomes
Paternal
Maternal
DCO Products
![Page 9: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/9.jpg)
Pedigree for ABO Blood Group and Nail-Patella Syndrome
![Page 10: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/10.jpg)
HIV-1 Structure
(Gp120)
![Page 11: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/11.jpg)
HIV Infection Pathway
Protein encodedBy CCR5-1 allele(CCR5-1 / CCR5-1 or CCR5-1 / CCR5-∆32)
HIV-1
Gp120
Cytosol
Extra-cellularSpace
Membrane
CCR5
![Page 12: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/12.jpg)
CCR5 RFLP
CCR5-1
CCR5-∆32
![Page 13: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/13.jpg)
CCR5 Genotype Analysis
Fig. 25-3
![Page 14: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/14.jpg)
CCR5-∆32 Allele Frequency
Fig. 25-4
![Page 15: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/15.jpg)
Assumptions of the Hardy-Weinberg Equation
1. Individuals of all genotypes have equal rates of survival and reproductive success (no selection).
2. No new alleles are created or converted from one allele toanother by mutation.
3. Individuals do not migrate into or out of the population(no gene flow).
4. The population is infinitely large (no genetic drift).
5. Individuals in the population mate randomly (no inbreeding)
Page 619-620
![Page 16: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/16.jpg)
Fig. 25-8
Changes in CCR5-∆32 Allele Frequency
![Page 17: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/17.jpg)
Fig. 25-7
Effect of Selection on Allele Frequency
![Page 18: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/18.jpg)
Pedigree Showing First Cousin Mating
![Page 19: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/19.jpg)
Genes comprise ~ 5% of genomeRepeated DNA comprises ~ 50% of genome (purple blocks)
VNTR (Variable Number Tandem Repeat)STR (Short Tandem Repeat)
Unique (“junk”) DNA comprises the rest
Organization of Human Genome
Fig. 20-8Pg. 494
(~ 50 kbp)
![Page 20: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/20.jpg)
STR-DSTR-CSTR-B STR-E STR-FSTR-A
Chromosome 7
![Page 21: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/21.jpg)
STR-DSTR-CSTR-B STR-E STR-FSTR-A
7M
7P
GTCTAG GTCTAG GTCTAGCAGATC CAGATC CAGATC
GTCTAG GTCTAG GTCTAG GTCTAG CAGATC CAGATC CAGATC CAGATC
7M
7P
![Page 22: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/22.jpg)
Fig. 22-27
RFLP Analysis of VNTR Locus
![Page 23: Genetic Map of Drosophila](https://reader035.vdocuments.site/reader035/viewer/2022062321/568131db550346895d984174/html5/thumbnails/23.jpg)
Fig. 22-28