final presentation
TRANSCRIPT
THE ENHANCEMENT OF ALUMINUM SURFACE AREA BY POLYMERS TEMPLATE ASSISTANCE
Prof. OtañoRISE Spring 2015Sara DiazPatricia RodriguezCamille RuizJustin Cotto
PROBLEM
✓Which polymer is easier to detach from the deposited Aluminum, in order to acquire an Aluminum nano-shell?
✓Hypothesis✓ Cellulose acetate detaches easily. ✓ Poly(vinyl alcohol) –Poly(acrylic acid) will only
detach when soaked in water.✓ Regenerated cellulose will not detach.
SIGNIFICANCE
Cancer therapy and bio imaging enhancement:Theranostic probesAuNP’s are biocompatible, have vivid optical properties, and the flexibility to have different molecules and materials attached to their shellScattering: AuNP’s become visible to imaging processes Absorption: Phototermal ablation Minimal damage to body cellsGold nanoshells are shuttled into tumors by phagocytosisA macrophage is formed
Alternative: Placing drugs inside nanoparticle and using it as a vehicleAccomplished by coating outside of a nanoparticle with iron oxideOnce the tumor area is coated with drug filled nanoparticles, they are activated
(Loo 2005)
TECHNIQUES UTILIZED
✓ElectrospinningCellulose Acetate
✓ Poly(vinyl alcohol) –Poly(acrylic acid)✓ Regenerated Cellulose✓Sputtering Deposition
SPUTTERING UTILITIES AND ADVANTAGES
Utility: Semiconductor industriesOptical applications: glasses and telescopesThin film transistorsLow emissivity coatings on glassFabrication of CD’s and DVD’s-Efficient Photovoltaic solar cells
Advantages: Materials with very high melting points are easily sputtered.Sputtered films typically have stronger adhesion on the substrateTarget contains large amount of material and is maintenance free Sputtering sources contain no hot parts and are compatible with reactive gasesSize and relative thickness of the nanoshell can be controlled by changing reaction time and plating concentration
CONCLUSION
✓Hypothesis was unable to be proven
✓Future projects:✓Evaluation of fibers through electron
microscope✓Characterization of fiber morphology✓Comparison of optimal templates
CITED LITERATURE
Loo C, Lowery A, Halas N, West J, Dezek R. 2005. Immunotargeted Nanoshells for Integrated Cancer Imaging and Therapy. Nano Lett. [Internet; cited May 14]. Doi: 10.1021/nl050127s. Recovered at: http://faculty.washington.edu/markeh/MSE599/Loo_Nanolett_2005.pdf
Ning Z, Xiongbiao C. 2013. Biofabrication of Tissue Scaffolds in book entitled. Advances in Biomaterials Science and Biomedical Applications. Recovered at: http://ppl.ippt.gov.pl/18-few-words-about/17-electrospinning
ACKNOWLEDGMENTS
RISE PROGRAM✓Dr. Eneida Diaz✓Dr. Elena Gonzalez✓Mr. Giovanni Cruz
✓Professor Ota-o and his students:✓Normarieli Passalacqua✓Alejandra De Jesus✓Xavier Ortiz