fast steps to success
TRANSCRIPT
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Can you design novel active ligands this easily? Ask to see < ^ BioCAChe and learn how...
Site l icenses and stereoscopic displays available To request a demonstrat ion of BioCAChe or
BioMedCAChe 6.0 (= BioCAChe + QSAR) email [email protected],
call 1 503 746 3602 (USA), or visi t www.CA.CheSoltwarex^
Fast steps to success...
1) Identify the active site Identify conserved residues by automatic sequence alignment
Locate active sites in homologs by sequence matching
Reveal potential binding sites with "Crevice Map"
Simplify protein I display with "Ribbons and Curls" analysis
2) Design a ligand in the pocket Ask about a FREE 3D-Stereoscopic Laptop computer with the purchase
-a of BioMedCAChe
Ligand docking & design aided by "Adjacent surface pocket"
Flexible or rigid docking Color by property...
Automatic H-bond & bump analysis Superimpose & compare ligands
3) Prescreen the virtual library
QSAR, QSPR, ADME / Tox, LogP, pKa, Rule-of-5, etc. screening*
Automated conformation searching
'BioMedCAChe only
mailto:[email protected]://www.CA.CheSoltwarex%5e
Fast steps to success...