etb funding success case: starlab - eurotransbio funding success case: starlab aureli soria-frisch...

Starlab Neuroscience

ETB Funding Success Case: Starlab Aureli Soria-Frisch (PhD)

Senior Researcher and Neuroscience Research Program Manager

| STARLAB BARCELONA | LIVING SCIENCE STARLAB NEUROSCIENCE

Starlab – a brief introduction

• A private R&D company based in Barcelona

•We transform Science into Technologies for our Clients

•We develop new products and services with profound and positive social impact

2

| STARLAB BARCELONA | LIVING SCIENCE STARLAB NEUROSCIENCE3

| STARLAB BARCELONA | LIVING SCIENCE ! STARLAB NEUROSCIENCE!

Starlab – a brief introduction!

3!

!"#$%&'#()*+,+$+"#)

-./01)2#(+#113+#()

41%3"$0+1#01)

-0+1#01)5")6/3715)*+,+$+"#)

)))))))))))-5/382/359)

)))))))))))))))))41%3"1&1053+0$)

products

• snow detec+on• jellyfish predic+on• smart irriga+on

• electrophysiology• electrical brain s+mula+on

R+D


Neuroscience Research – What we offer

4

Less of this ...



5

Less of this ...More of this!



6

Less of this ...More of this!



7

Physiological Data Analysis• Protocol defini+on• Data collec+on• Data cleaning and ar+fact removal• Feature extrac+on and valida+on• Effect classifica+on• Study valida+on• Data Analysis Support for Experimental Work and Clinical Trials

Physiological Sensor Systems• Requirements analysis• Electronic design• Industrial design• Fast prototyping• Test and valida+on

Algorithms• Signal Processing• Computa+onal Intelligence• Machine Learning• Data-‐mining• Modeling and simula+on• Data fusion and integra+on


NeuroscienceNeuroscience - Know-how

Hardware• Fast prototyping• Sensor technologies• Embedded systems• Wireless communica+ons• Industrial design

EEGtCS

SUENO


Funded Research

• Building prototypes• Ideas harves@ng• Exploring new territories


NeuroscienceFunded Research

user state

8

BCI

physiologicalbiometrics

Application Areas

brain sCmulaCon


CombinationBCI withAssistive Technologies

• Motor imagery• SSVEP• EOG, EMG based

Brain Computer Interfaces


Biometry

12


Brain Electrical Stimulation

13


Changes in the Comma Recovery Scale aEer tDCS

Brain Electrical Stimulation


EEG biomarkers


EEG biomarkers

16

We use EEG features to predict Parkinson’s 10years in advance


User State

17


User State

• Emotional state• Stress• Sleep\Alertness• Mental Workload

18


SUENO project - goals

19

• Sleep analysis through electrophysiological signals‣ Automate algorithms for sleep

analysis‣ Further development of

electrophysiological sensor device


SUENO project - work plan

WP1SoA and

requirements

WP2Algorithms development

WP3Device

development

WP4Experimental valida+on

WP5Market analysis

WP6Project

management


WP3 Device development

• Original electrophysiological device - Enobio• Frontal electrodes• Band cap for electrode positioning• System was not suitable for sleep studies


• First development - Enobio 2G• New electrode design in order to allow hair areas positioning• New electrode cap for full scalp monitoring



WP4 Validation

• Recording campaigns‣ Sleep Dept. Sabadell Hospital – C.S. Parc Taulí‣ Siesta Group


• Validation proposed improvements‣ Improve communication stability‣ Place somewhere else electronic box‣ Improve electrode holder to avoid contact loss during night‣ Nice to have dry electrodes to reduce preparation time



• Final validation ‣ System is validated for detection of sleep macrostructure -

performance equal to standard systems‣ For sleep microstructures detection further improvements are

needed• Final device features - Enobio 3G

‣ Standard Bluetooth communication‣ Larger capability - 20 channels at 500 Hz‣ Improved and more flexible electrode cap‣ Dry electrodes

WP4 Validation


Enobio 3G

• Wearable• Wireless• Easy to Use

26

Neuroelectrics in a nutshell…

Date of foundation: May 2011.

Headquarters: Barcelona, Spain.

CEO: Ana Maiques.

Staff: 4.

Aim: Investigate, develop and market products in the neuroscience area.

Mission:

“To become the trusted leader in Brain Health treatment by providing measurement tools and

making neuromodulation affordable and available for every patient in need”.

General facts

The company has two products:• Enobio: a wireless electroencefalograpy

system, monitoring brain activity in an easy way and already in the market

• Starstim: a novel neurostimulator using tDCS-transcraneal direct current stimulation to treat, amongst others:

• Chronic Pain• Post-Stroke Rehabilitation

Company focus

2

Enobio new family of products.

4

TARGET MARKETS: Research (CE since Feb 2012) and Medical (CE Medical since April 2012)

20832 on the pipeline

5

Signals you can trustFaithful reproduction of the raw EEG signal.Get the reliability of a wired system without the wiresCapture all the data you need

Quality EEG made easyStart recording in less than one minuteEasily visualize and manage your dataRecord where and when you want

Advanced development toolsWork with raw dataBuild your own applicationsSafeguard and organize your research

Features

7

NIC visualization and analysis software:• User-friendly EEG visualization• Intuitive time-frequency analysis• Customizable user interface

Software


EEG biomarkers

33

Parkinsonʼs

Alzheimerʼs

ADHD

Schizophrenia


EEG biomarkers

33

Parkinsonʼs

Alzheimerʼs

ADHD

Schizophrenia

Diagnosis


EEG biomarkers

33

Parkinsonʼs

Alzheimerʼs

ADHD

Schizophrenia

Diagnosis

Prognosis


Physiological Data Consulting Service

34

data

largest informa+onat reduced costs

automate knowledgegenera+on

summaryreport

hypothesislaunching

Data analysis partnerfor pharma industry


Cognitive Enhancement

35

Study at Oxford University: tDCS for math skill boos+ng



35

Demen@a




35

Demen@amTBI




35

Demen@amTBIHealthy subjects?




35

Demen@amTBIHealthy subjects?Study aid?



Sports Performance

36


Neuromarketing

37

Mul+-‐modal emo+on recogni+on: We gather emo+onal response of subjects by using electrophysiological sensors and facial expression recogni+on


tCS Applications enter mainstream

• Chronic pain• Depression• Post-stroke rehabilitation• Dementia• Addiction• …

38

Pilot using tDCS for stroke rehabilita+on by our partners at Burke Rehabilita+on Centre


tCS Applications enter mainstream

• Chronic pain• Depression• Post-stroke rehabilitation• Dementia• Addiction• …

• Improve therapies– Non-invasive– Safe– No known side effects– Precise targets

38

Pilot using tDCS for stroke rehabilita+on by our partners at Burke Rehabilita+on Centre

Thanks for your [email protected]

39

etb funding success case: starlab - eurotransbio funding success case: starlab aureli soria-frisch...

Documents