efector functions of cd4 + and cd8 + t-cells. naivna cd4 + t naive cd4 + t th1 th2 th17 defense-...
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Naivna CD4+TNaive CD4+T
Th1
Th2
Th17
Defense- intracellular pathogens, stimulation of IgG production
Defense- helmints
Defense- extracellular bacteria, fungi
Organ-specific autoimmune diseases
Allergy
Autoimmunity and chronic inflammation
Naivna CD4+TNaive CD4+T
Th1
Th2
Th17
IL-4
IL-12
IL-23
T-bet
GATA-3
RORt
IL-4IL-5IL-13
Macrofage activation
B-cells
EosinophilactivationB-cells…
Neutrophil activation...
IL-17IL-22
IFN-γ
Naivna CD4+TNaive CD4+T
Th1
Th2
Th17
Defense- intracellular pathogens, stimulation of IgG production
Defense- helmints
Defense- extracellular bacteria, fungi
Organ-specific autoimmune diseases
Allergy
Autoimmunity and chronic inflammation
Naivna CD4+TNaive CD4+T
Th1
Th2
Th17
Defense- intracellular pathogens, stimulation of IgG production
Defense- helmints
Defense- extracellular bacteria, fungi
Organ-specific autoimmune diseases
Allergy
Autoimmunity and chronic inflammation
Naivna CD4+TNaive CD4+T
Th1
Th2
Th17
Defense- intracellular pathogens, stimulation of IgG production
Defense- helmints
Defense- extracellular bacteria, fungi
Organ-specific autoimmune diseases
Allergy
Autoimmunity and chronic inflammation
killing virus-infected and tumor cellsj.CTL killing mechanisms are10.
perforin, granzymes, Fas-FasL interaction
i.CTL effector function is9.
intracellular pathogensh.IL-178.
IFN-γ production and macrophage activation g.
IL-4 and IL-13 induce also7.
mobilises and activates neutrophilsf.TH2 subpopulation induces6.
alternative macrophage activatione.TH2 cells are important for defense against
5.
TH1, TH2 i TH17d.TH2 effector function is4.
helminatsc.TH1 cells are important for defense against
3.
Inflammatory reaction rich in eosinophilsb.TH1 effector function is2.
production of IL-4, IL-5, IL-13a.Subpopulations of efektor CD4+ T-cells are
1.
1._____ 2._____ 3._____ 4._____ 5._____ 6._____ 7._____ 8._____ 9._____ 10.____d. g. h. a. c. b. e. f. j. i.