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TRANSCRIPT
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ECG Ischemic Changes
Dr. Zohair Alaseri FRCPc, Emergency Medicine FRCPc, Critical Care Medicine
Chairman Department of Emergency Medicine Intensivest and Emergency Medicine Consultant
King Saud University Hospitals Riyadh, KSA
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ECG Ischemic Changes
• Introduction • ECG Ischemic Changes • ST Elevation MI (STEMI)
– Anterior STEMI – Lateral STEMI – Inferior STEMI – Right Ventricular STEMI – Posterior STEMI – Combined STEMI
• Non ST Elevation MI (STEMI) • Old MI • Ischemia with
– Bundle branch block – Paced rhythm – Lt ventricular hypertrophy
Content
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Introduction
ECG Ischemic Changes
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The three major coronary arteries that supply blood to the heart.
Location of MI
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Location of MI
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Localizing myocardial ischemia, injury or infarction using the 12-lead ECG.
Location of MI
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Location of MI Indicative Changes Reciprocal Changes
Anterior V1 to V4 I, aVL, II, III, aVF Septal
V1, V2
I, aVL
Inferior
II, III, aVF
I, aVL, V1 to V4
Posterior
None
V1 to V4
Lateral
I, aVL, V5, V6
II, III, aVF, V1, V2
RV
V3 R to V6R
Location of Ischemia
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Right Leads
V1R is same as standard V2, V2R is the same as standard V1, V3R is halfway between V2R V4R, V4R is fifth intercostals space at right midclavicular line, V5R is same level as V4R in right anterior axillary line V6R is same level in right midaxillary line
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V7, posterior axillary line; V8, posterior scapular line; V9, left border of spine.
Posterior Leads
All in the same horizontal plane of V4
to V6
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STEMI
ECG Ischemic Changes
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Zones of ischemia
Reciprocal changes often seen in leads not directly facing the involved area
Indicative changes of ischemia, injury, and necrosis seen in leads facing the injured area.
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ST segment shape
plateau shaped dome shaped
obliquely elevated. dome shaped
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ECG patterns associated with acute myocardial injury
Straightening of the ST segment that slopes up to the peak of the T wave without spending any time on the baseline
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Evolution of STEMI
lead III
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normal concave upward
Evolution of ST segment elevation
straight convex more ST elevation, confirming
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earliest phase, tall positive (hyperacute) T waves are seen in leads V2 to V5.
Hours later, marked ST elevation & abnormal Q is present in the same leads
Evolution of STEMI
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Evolution of T-wave inversion
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Pseudonormalization of inverted T waves.
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Reciprocal ST-T changes in the inferior leads (II, III, and aVF).
Acute phase ST elevations and new Q waves
Evolving phase: deep T wave inversions
Resolving phase: partial or complete regression of ST-T changes
Evolution of STEMI
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Four examples of hyperacute T waves
• T wave is very large compared with QRS
• depressed ST segment take-off and straightening of the ST segment
• wide and bulky, much larger than QRS.
• This less common form is very peaked and tented T wave
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Anterior STE with QS waves and terminal T-wave inversion. QS waves suggest prolonged occlusion and deep T-wave inversion suggests (late)
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Hyperacute T waves & ST elevation Proximal LAD occlusion
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STE (inferior, anterior, lateral)
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This patient's chest pain had resolved recently and he now has subtle biphasic terminal T-wave inversion in lead V2
Wellens syndrome
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Early (LAD) occlusion. • diffuse STD in inferior and lateral leads • STE in V1. • straightening of ST segments in leads V2 and V3,with slightly large T waves.
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High STE in V1–V4 with upwardly concave ST segments, but also STE in lead aVL with reciprocal depression in inferior leads.
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LAD occlusion manifesting as tall T waves that tower over a tiny R wave (V3)
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• (hyperacute) T waves
• slight ST segment elevations
• reciprocal ST dep leads II, III, and aVF.
STEMI
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34-year-old male. What's going on here
ECG shows classic findings of acute/hyperacute anterior MI with reciprocal inferior ST depressions
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ST Acute ST elevation inferior wall infarction
STEMI
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Hyperacute T & ST elevations localized in the anterior leads.
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ECG Ischemic Changes
Ischemia & Rt or Lt bundle Branch Block (RBBB & LBBB)
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LBBB with AMI
BBB & Ischemia
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• The ECG shows a prolonged PR with (RBBB) • The wide notched R waves (RSR' equivalent) in V1-V3 are due to the RBBB. • The rather prominent initial R wave in V2-V3 due to posterior MI on the RBBB.
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reciprocal ST depressions in II, III, and aVF.
AAMI & RBBB + bifascicular block
Q waves and ST elevations in I and aVL
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Prominent Q in the lt chest leads as part of QR complexes
ST elevations in the left chest leads or in other leads with prominent R waves as in lead V5
ST segment depressions in the rt leads
T wave inversions in leads V1 to V3 as in previouse slide
STEMI & LBBB
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Elderly female presented to the emergency ward with shortness of breath
Sinus bradycardia, inverted T waves suggesting that a "primary" or ischemic process is evolving in the inferior distribution + LBBB )
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STE (leads V2–V6, I, and aVL) reciprocal STD(leads II, III, and aVF)
RBBB with AMI
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Concordant STE and upright T waves in leads I, aVL, V5, and V6. Concordant reciprocal STD in the inferior leads II, III, and aVF.
STEMI in the presence of LBBB
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T wave inversions in leads V1 to V3
LBBB + ischemia
LBBB
STEMI & LBBB
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58-year-old man with chest pain
Acute anteroseptal MI & RBBB.
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AMI and LBBB concordant ST-segment elevation in leads V3, V4, V5, and aVf. Excessive discordant ST-segment elevation in lead III
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AMI and LBBB pattern excessive discordant ST-segment elevation in leads V2, V3, V4 concordant ST-segment elevation in Lead V5
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• circumflex artery occlusion • indicative changes in leads I, aVL, and
sometimes V5–6 • reciprocal changes in inferior or anterior
leads. • Lateral wall MI does not often occur alone
but commonly accompanies anterior MI
Lateral Myocardial Infarction
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STE is 0.5 mm in leads I and aVL
Lateral Myocardial Infarction
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STD in leads II, III, and aVF
There is left anterior fascicular block
STE is 0.5 mm in leads I and aVL
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Acute anterolateral wall MI. ST elevation is present in I, aVL, and V2–V6. Reciprocal ST depression is present in III, aVF, and aVR.
STEMI
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• is usually due to occlusion of the right coronary artery and is diagnosed by indicative changes in leads II, III, and aVF.
• Reciprocal changes are often seen in leads I, aVL, or the V leads.
• In people with left dominant coronary circulation, the circumflex artery supplies the inferior surface of the heart and circumflex occlusion is the cause of inferior MI.
• Lead III can have a Q wave normally • Approximately 40% of inferior MIs involve the
right ventricle
Inferior MI
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Elderly female presented to the emergency ward with shortness of breath
Sinus bradycardia, inverted T waves suggesting that a "primary" or ischemic process is evolving in the inferior distribution + LBBB )
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ST elevation is present in II, III, aVF, and V1; reciprocal ST depression in all other leads
Acute right ventricular MI.
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• due to right coronary artery occlusion or to circumflex occlusion in left-dominant circulation and usually occurs in conjunction with inferior MI.
• 12-lead ECG there are no leads that face the posterior wall, and, therefore, no indicative changes are recorded.
• reciprocal changes in the anterior leads, especially V1 and V2, but often all the way to V4.
• taller R wave than normal V1 and V2 • ST-segment depression • upright, tall T waves • confirmed by recording posterior leads and observing ST
elevation
Posterior MI
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STD in V2 and V3 diagnostic of posterior STEMI STE in lead III is >STE in lead II
Inferior-posterior STEMI
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Acute posterior wall MI.
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• first degree AV block, RBBB, inferior and possibly posterior (MI). • The prominent initial R waves in V2 and V3 in this due to associated posterior MI and/or the RBBB alone. • T waves are upright in leads V2 and V3, whereas uncomplicated RBBB should produce secondary T wave inversions in leads.
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V7, posterior axillary line; V8, posterior scapular line; V9, left border of spine.
Posterior Leads
All in the same horizontal plane of V4
to V6
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Large R waves and ST depression in V1 and V2.
Posterior wall MI.
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Notice the tall R waves
Posterior Infarction
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• Right ventricular MI (RVMI)occurs in up to 45% of inferior MI • ST-segment elevation in V1 as well, because V1 is the chest lead
that is closest to the right ventricle. • ST-segment elevation in V1 together with ST-segment elevation in
the inferior leads is suspect for RVMI. • Another clue is discordance between the ST segment in V1 and the
ST segment in V2. • Discordance means that the ST segments do not point in the same
direction—V1 shows ST-segment elevation, whereas V2 is either normal or shows ST-segment depression.
• Leads V3R through V6R develop ST-segment elevation when acute RVMI is present.
• Lead V4R is the most sensitive and specific lead for recognition of RVMI.
Right Ventricular MI
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Right Leads
V1R is same as standard V2, V2R is the same as standard V1, V3R is halfway between V2R V4R, V4R is fifth intercostals space at right midclavicular line, V5R is same level as V4R in right anterior axillary line V6R is same level in right midaxillary line
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Right Ventricular MI
Right-sided chest leads in a patient with acute RVMI. • ST elevation in leads V3R–6R. • standard V1 shows ST elevation while • standard V2 shows a normal ST segment (a form of “discordance”)
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ST elevation is present in II, III, aVF, and V1; reciprocal ST depression in all other leads
Acute right ventricular MI.
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Right-sided leads reflecting RV involvement. STE in the inferior leads (leadIII>lead II),
Inferior & RV MI
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• Inferior STE & reciprocal STD • STE in lead V1 is typical for RV AMI • widespread STE
Inferior & RV MI
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Acute infero-postero-lateral myocardial infarction
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• A. fib with subtle signs of acute inferior (MI) with ST elevations intermittently apparent in leads II, II and aVF.
• The right-sided chest leads show evidence of concomitant (RV) MI with slight ST elevations in leads V4R to V6R.
70-yr-old man presents with severe chest pain, nausea, vomiting and diaphoresis. Right-sided chest leads are shown (i.e., V1R to V6R).
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Inferior-posterior myocardial infarction (MI).
Tall R waves in V1-V2 in a 48-year-old man. These were due to....
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Subendocardial ischemia
• The subendocardium is particularly vulnerable to ischemia because it is most distant from the coronary blood supply and closest to the high pressure of the ventricular cavity.
• ST segment depression is the most common ECG change
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• T-wave inversion • ST-segment depression
of 0.5 mm or more • ST segment that remains
on the baseline longer than 0.12 second
• ST segment that forms a sharp angle with the upright T wave
• tall, wide-based T waves • inverted U waves
Familiar pattern of ischemia:
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subendocardial ischemia
ECG shows ST segment depression (except in lead aVR, which typically shows ST elevation).
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NSTEMI
ST segment depression. Leads V1–V6only
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ANGINA PECTORIS
ST depressions seen during an attack. When the pain disappears, the ST segments generally return to the baseline.
Normal
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Marked, diffuse ST depressions in leads I, II, III, aVL, aVF, and V2 to V6 ST elevation in lead aVR.
Subendocardial ischemia.
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NSTEMI
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Prinzmetal's angina
• ST segment elevations are transient. After the episode of chest pain,
• ST segments usually return to the baseline, without the characteristic evolving pattern of Q waves and T wave inversions.
• it is a marker of coronary artery spasm that causes transient transmural ischemia.
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The baseline resting ECG shows nonspecific inferior ST-T changes
With chest pain, marked ST segment elevations occur in leads II, III, and aVF, and reciprocal changes
The ST segments return to baseline after the patient is given nitroglycerin
catheterization showed severe RCA obstruction with intermittent spasm producing total occlusion and transient ST elevations.
Prinzmetal's angina
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ECG Ischemic Changes
Ventricular Paced Rhythm
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Right VPR with AMI.
Concordant ST-segment depression in lead V1, V2, or V3. Concordant
ST-segment elevation
Excessive, discordant ST-segment elevation.
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Right VPR with appropriate ST-segment andT-wave locations and configurations.
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Right VPR with AMI. concordant ST-elevation in leads II, III, and aVf excessive, discordant ST elevation leads V3 and V4
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Ventricular paced rhythm with underlying complete heart block (P waves march through). hyperacute ST-T changes inferiorly and laterally with reciprocal change V1-V3 consistent with acute infero-postero-lateral MI
A 68-year-old man with dyspnea. What does the ECG show?
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>5 mm ST segment elevation in right precordial or inferior leads, and especially ST depressions/T wave inversions in leads with QS or rS complexes, are highly suggestive of ischemia.
Why is this patient with a dual chamber pacemaker & presyncopal
inferior (MI). elevated J point and convex ST segment elevations inferiorly, with reciprocal changes in I, aVL, and V2.
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ECG Ischemic Changes
Left Ventricular Hypertrophy pattern & Ischemia
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absence of ST-segment and T-wave changes
Predominantly positive QRS complexes with ST- depression and T-wave inversion
Predominantly negative QRS complexes with ST-segment elevation and upright T wave.
ECG in LVH
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LVH pattern with progressive abnormality demonstrating increasing ST-segment elevation and changing morphology of elevated ST segment
Ischemia & LVH
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12-lead ECG with left ventricular hypertrophy pattern. Note absence of ST-segment and T-wave changes.
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ST-segment elevation in leads V2 and V3 with obliquely straight form of ST segment, anterior AMI.
12-lead ECG with left ventricular hypertrophy pattern
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ECG Ischemic Changes
Old Ischemia
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Q waves
• Not all Q waves are indicators of MI. • Q wave is normally seen in lead aVR. • Small “septal” q waves are normally seen
in the left chest leads (V4 to V6) and in one or more of leads I, aVL, II, III, and aVF.
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Q wave is generally abnormal if its duration is 0.04 second or more in
• lead I • all three inferior leads (II, III, aVF) • leads V3 to V6.
• Lead V2: any Q wave • Lead V3: almost any Q wave
• A Q wave of depth >25% of R wave height is often quoted as diagnostic, but width is more important than depth
Q waves
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Early acute anterior wall MI. R wave progression in V1–3
ST elevation with tall wide-based T waves in V2–4.
9 hours later
Q waves have developed in V1–4
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Q waves ST segments are coming down
Early acute inferior wall MI
next day
reciprocal resolved.
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Old Lateral wall infarction & RBBB.
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Thank You