Feb 1st, 2008
GYN SPECIAL EDITION NUMBER 2
24 year old female. ThinPrep papA. LSILB. HSILC. ASCUSD. Squamous MetaplasiaE. Endocervical Cells
1
2
34 year old female. ThinPrep papA. Reactive endocervical cellsB. Squamous metaplasiaC. ASCUSD. LSILE. HSIL
3
34 year old female. ThinPrep papA. ASCUSB. LSILC. HSILD. Squamous MetaplasiaE. Reactive/Inflammatory
4
29 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. ASC-USD. LSILE. HSIL
5
32 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. ASC-USD. LSILE. HSIL
6
23 year old female. ThinPrep papA. Squamous metaplasiaB. ParakeratosisC. LSILD. HSILE. SCCA
7
18 year old female. ThinPrep papA. CMVB. HIVC. HPVD. HSVE. EBV
8
52 year old female. ThinPrep papA. Reactive endocervical cellsB. Normal endometrial cellsC. AISD. AdenocarcinomaE. HSIL
9
44 year old female. ThinPrep papA. Squamous metaplasiaB. Reactive endocervical cellsC. AtrophyD. LSILE. HSIL
10
34 year old female. ThinPrep papA. ReactiveB. ASCUSC. LSILD. HSILE. Squamous Metaplasia
Answers
1. D Squamous Metaplasia• Nuclei not enlarged, smooth contours, NC ratio OK. Not HSIL.
2. A Endocervical cells• Small round and regular nuclei. Compare to Ques #1.
3. E Reactive• See the trichomonas organism!
4. D LSIL• Koilocytes!
5. D LSIL• Koilocytes!
6. B Parakeratosis• Sometimes associated with dysplasia
7. D HSV• Herpes Simplex Viral changes in Nucleus
8. D Adenocarcinoma• Crowded overlapping nuclei with prominent nucleoli. No “feathering” so not Adeno in situ (AIS)
9. E HSIL• High NC ratio, irregular nuclei. This actually turned out to be a SCCA on biopsy.
10. A Reactive• No dysplasia, just some squamous cells with neutrophils.
