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Institut Català d’Oncologia
dCOT study phase 4
Pattern of use, acceptability and perceived risk of
electronic cigarettes: a prospective cohort study
with biomarkers
Jose M Martínez-Sánchez, PhD, MPH, BSc
Tobacco Control Unit | WHO Collaborating Center for Tobacco Control
Catalonia Institute of Oncology
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Institut Català d’Oncologia
- In 2003, Hon Lik invented the e-cigarette
- During the first years, e-cigs were only available online
- During 2012-2013 the specialized shops of e-cigs proliferated around the world
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Institut Català d’Oncologia
«don’t kill the enemy of our enemy»
Jean-François Etter
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Institut Català d’Oncologia
Simple search in the PubMed:
(“e-cigarettes” [ti] OR “electronic cigarettes” [ti] OR e-cig* [ti] OR electronic cig* [ti] OR electronic nicotine delivery system [ti])
908 references, of them 509 have an abstract (56%)
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Institut Català d’Oncologia
dCOT studies
2004-05 2013-14
Law 28/2005 Law 42/2010
2011-12 2016-17
dCOT4
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Institut Català d’Oncologia
dCOT-4
cohort of e-cigarette users
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Institut Català d’Oncologia
1) To identify the pattern of use of electronic cigarettes in the cityof Barcelona.
2) To describe the perception of risk and motivation for using the electronic cigarettes.
3) To analyze the influence of electronic cigarettes on the consumption of conventional tobacco according to the users' characteristics and their pattern of use.
4) To characterize the levels of propylene glycol and main metabolite (propylene glycolglucuronic) in urine and saliva of users of electronic cigarettes.
5) To compare the levels of nicotine, cotinine and carcinogens inurine and saliva of users of electronic cigarettes with a sampleof conventional tobacco smokers.
Objectives
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Institut Català d’Oncologia
Methods
We will recruit a representative sample of adult (≥18 years old) e-cigarette users of the city of Barcelona (n=720)
We will follow them up 6 and 12 months after the recruitment
6.5% ever e-cigarettes users: 1.6% current users, 2.2% past users, and 2.7 experimentation with e-cigarettes
25,600 e-cigarette users in the city of Barcelona
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Institut Català d’Oncologia
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Institut Català d’Oncologia
Contents of the questionnaire
-Socio-demographic questions
-Use of conventional cigarettes and other types of tobacco
-Characteristics of use (brand, nicotine, flavor, ml per week, etc)
-Health effects
-Motivation to use electronic cigarettes
-Perception of usefulness and harmfulness of e-cigarettes
-Support to e-cigarette regulation and use of e-cigarettes in different venues
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Institut Català d’Oncologia
Tobacco Control Unit
Thanks