Download - Dasatinib ( nM ) 0 0 0.1 0.5 1 5
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Dasatinib (nM ) 0 0 0.1 0.5 1 5 M-CSF - + + + + +
WB: Phospho-Erk
WB: Erk
WB: Phospho-Akt
WB: Akt
B Dasatinib (nM) 0 0 0.5 1 5 10M-CSF - + + + + + WB: Phospho- FMSY708
WB: FMS
Dasatinib (nM ) 0 0 0.1 0.5 1 5 M-CSF - + + + + +
Wb: Phospho-Akt
Akt
Figure S1Si
de s
catte
r
0 50K 100K150K200K250K 0
50K
100K
150K
200K
250K
Forward scatter0
CD14- FITC102 103 104 105
0
40
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120
160
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Cel
l eve
nt c
ount
88.6
C D
Dasatinib (nM) 0 0 0.5 1 5 10M-CSF - + + + + +
WB: Phospho-FMS Y708
WB: FMS
A
20
406080
100120
No M-CSF
0 0.5 1Imatinib (μM)
20406080
100120
0 0.5 1Imatinib (μM)
% m
acro
phag
e su
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al
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M p
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m2
G H
I J
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