disorders of the peripheral vascular system arterial (non-cardiac) and venous
TRANSCRIPT
Disorders of the Peripheral Vascular System
Arterial (Non-Cardiac) and Venous
Objectives
• Describe peripheral vascular disorders• Name 8 common peripheral vascular disorders• Explain the pathophysiology of peripheral
vascular disorders.• Describe nursing interventions in caring for
clients with peripheral vascular disorders.
Assessment of Arterial and Venous Circulation
• Pulse – may be decreased r/t poor blood flow• Appearance – may be discolored, shiny, scaly• Temperature – may be cool or abnormally warm• Capillary refill – poor blood flow = >3sec• Hardness – hard = chronic stasis, risk of ulceration• Edema – pitting may indicate acute edema• Sensation – pain or numbness and tingling
Arterial Diseases (Non-Cardiac)
Peripheral Arterial Disease
PAD Risk Factors• P.A.D. is caused by the build-up of fatty deposits (plaque) and cholesterol
in the arteries outside the heart.
The First Tool to Establish the PAD Diagnosis:A Standardized Physical Examination
Pulse intensity should be assessed and should be recorded numerically as follows:
– 0, absent– 1, diminished– 2, normal
– 3, bounding– 4, Cannot be
obliterated
Use of a standardexamination should
facilitate clinicalcommunication
Ankle Brachial Index
• A technique in which a hand held doppler is used to measure the ratio of ankle systolic BP to the highest brachial blood pressure
• Normal = 0.91-1.30• Mild PAD = 0.71-0.90• Moderate PAD = 0.41-0.70• Severe PAD = < 0.40
http://www.nhlbi.nih.gov/health/dci/Diseases/pad/pad_diagnosis.html
ABI Procedure
Using the ABI: An ExampleNormal = >0.90
ABI=ankle-brachial index; DP=dorsalis pedis; PT=posterior tibial; SBP=systolic blood pressure.
Right ABI80/160=0.50
Brachial SBP160 mm Hg
PT SBP 120 mm Hg
DP SBP 80 mm Hg
Brachial SBP150 mm Hg
PT SBP 40 mm HgDP SBP 80 mm Hg
Left ABI120/160=0.75
Highest brachial SBP
Highest of PT or DP SBP
aABA
Interpreting the Ankle-Brachial Index
Adapted from Hirsch AT, et al. J Am Coll Cardiol. 2006;47:e1-e192. Figure 6.
Exercise ABI Testing: Treadmill
• Indicated when the ABI is normal or borderline but symptoms are consistent with claudication*.
• If the ABI results fall post-exercise - supports a PAD diagnosis;
• May “unmask” PAD, if resting ABI is normal.
*Claudication = tissue ischemia
.
Magnetic Resonance Angiography (MRA)
• MRA has virtually replaced contrast arteriography for PAD diagnosis
• Excellent arterial picture
Computed Tomographic Angiography (CTA)
• Requires iodinated contrast
• Requires ionizing radiation
• Produces an excellent arterial picture
Symptoms of Peripheral Artery Disease
• Terms: – Claudication: the process of activity ischemia LE
pain in affected extremity; usually subsides with rest
– Intermittent Claudication = a weakness of the legs accompanied by cramping pains in the calves caused by poor circulation of blood muscles.
Symptoms of Peripheral Artery Disease
Asymptomatic: Without obvious symptomatic complaint (but usually has an ABI of <.90)
Classic claudication: Lower extremity symptoms confined to the muscles with a consistent (reproducible) onset with exercise and relief with rest
“Atypical” leg pain: Lower extremity discomfort (foot, toe, or leg pain) that is exertional but that does not consistently resolve with rest
Signs and Symptoms of Peripheral Artery Disease
Critical limb lschemia: Pain at rest, non-healing wound (8-12 weeks), or gangrene
Acute limb ischemia (Arteriosclerosis Obliterans): The five “P”s, defined by the clinical symptoms and signs that suggest potential limb jeopardy:
- Pain- Pulselessness- Pallor- Paresthesias- Paralysis - (& polar sensation (coldness), as a sixth “P”).
Options in Limb Revascularization
• Endovascular reconstruction options– Percutaneous transluminal angioplasty (PTA)– Stents
• Surgical reconstruction options– Endarterectomy– Embolectomy– Aortoiliac/aortofemoral reconstruction– Femoropopliteal bypass (above knee and
below knee)– Femorotibial bypass
Critical Limb Ischemia – Nursing Interventions
• Assessment: 5- P’s• Maximize tissue perfusion– Treat pain– Reduce risk factors– Positioning
• Reposition at least every 2 hours• Avoid crossing legs• Legs in dependent position if tolerated by patient• Keep linens off extremity by using foot cradle
– Avoidance of vasoconstrictors• ETOH, nicotine, stress, cold
Post-op Surgical Revascularization: Nurse Management
• Monitor VS• Assess 5 P’s• Check peripheral pulses (doppler) frequently• Check operative site for bleeding or infection• Measure abdomen for increasing size• If symptoms of bleeding or rupture occurs,
immediate intervention needed
Thromboangiitis Obliterans(Buerger’s Disease)
• Disorder of unknown cause where the small and medium-sized arteries become inflamed and thrombotic
• Affects primarily the feet and hands
Strong correlation with smoking: The classic Buerger’s Disease patient is a young male (e.g., 20–40 years old) who is a heavy cigarette smoker. • Confirmed by angiogram
Signs and Symptoms of Beurger’s Disease
• Extremely painful, especially in non-diabetics with normal sensation
• Claudication: Pain induced by insufficient blood flow during exercise
• Most common in the Orient, Southeast Asia, India and the Middle East
• Decreased perfusion– Cold, pale, skin– Ulcers, necrosis of skin
• Sensitivity to cold
Medical Management
• Focus is on preventing progression of the disease by modifying risk factors
• In many cases quitting smoking will cure the disease
• Surgical intervention may be necessary in cases of advanced necrosis
• Surgical interruption of nerve pathways may be performed (rarely) in cases involving extreme pain
Raynaud’s Disease
• Intermittent arterial spasms causing ischemia to the periphery
• Usually precipitated by cold or emotional stimuli
• Cause is unknown• May be associated with other autoimmune
conditions
Signs and Symptoms of Raynaud’s Disease
• Chronically cold hands and feet
• Pallor• Numbness• Cyanosis of nailbeds• Pain
Medical Management
• Diagnosed by cold stimulation test– Skin temperature changes are recorded after
submersion in ice bath• Submerge patient’s hand in an ice water bath for 20
seconds and record ongoing temperatures• Skin temperature changes are recorded by a thermistor
attached to each finger
Medical Management
• Medications used to treat– Calcium channel blockers• Relax smooth muscles of the arterioles
– Relaxation and stress management– For extreme pain, surgical intervention may
interrupt nerve pathways
Raynaud’s Patient Teaching
• Avoid temperature extremes
• Avoid vasoconstricting agents
• Wear mittens/gloves and warm socks for any exposure to cold– Weather– Fridge/freezer or frozen foods
Arterial Aneurysm
• True Aneurysm– Focal dilation within an artery. – Differentiated from pseudoaneurysm because the
dilated area of the vessel contains all three layers. – Common Etiologies:• Atherosclerosis• Congenital or genetic predisposition (Marfan’s)• Trauma to vessel wall (usually causes pseudoaneurysm)
Arterial Aneurysm
• Marfan Syndrome– A connective tissue multisytemic disorder– Characterized by skeletal changes, long limbs, joint
laxity, cardiovascular defects (aortic aneurysm, mitral valve prolapse), mutation in the fibrin-1 gene.
Arterial Aneurysm– Risk (higher with smoking and hypertension)• Rupture• Dissection• Thromboembolism
– Common Locations• Abdominal Aorta• Ascending Aorta (Aortopathy, also associated with
bicuspid aortic valve)• Popliteal• Cerebral Aneurysms (increased risk of SAH)
Types of Arterial Aneurysms
• Fusiform
• Saccular
• Dissecting or Pseudo- aneurysm
Arterial Aneurysm
• Signs and Symptoms– Dependent on location of aneurysm– Pulsating mass may be felt in superficial arteries– Symptoms may be due to:• Local mass effect/compression of other structures• Hoarsness, low urine output, GERD
– Rupture• Low BP, Pain
– Thromboembolism
Aneurysm Rupture
• Aortic aneurysm ruptures present with severe chest, back, or abdominal pain (depending on location) and are often fatal
• Cerebral aneurysm ruptures present with “worst headache of life” and subarachnoid hemorrhage (SAH). Also may have stroke symptoms
Medical Management
• Control of HTN is essential to reduce the risk of rupture– Beta blockers are especially preferred due to
slowing of heart rate and the rate of rise of blood pressure
• Surgical intervention to repair aneurysm varies depending on type and location of aneurysm
Nursing Care
• Nursing management of pre-operative aneurysm pt. focuses on controlling HTN (with medication) and monitoring for s/s of rupture– Pallor, weakness, tachycardia, hypotension, sudden onset
abdominal, chest, back or groin pain; abd. pulsating mass
• Post-operative management focuses on maintaining effective tissue perfusion
• Teaching includes prevention and management of atherosclerosis and HTN– Risk Factor Reduction
Venous Disorders
Venous Insufficiency• Blood regurgitates through the valves in the veins
and then “leaks” into the tissue, causing edema• Chronic venous insufficiency can cause an area of the
skin to turn darker and become dry and scaly• Eventually chronic edema (stretching) can lead to
ulcerations of the skin
Normal Blood Flow
Venous Stasis
Venous Stasis Ulcer
Venous Stasis Ulcers
• Occur from chronic deep vein insufficiency and,
• Stasis of blood in the venous system of the legs
• A leg ulcer = an open, necrotic lesion – Results when an inadequate supply of oxygen-rich
blood and nutrients reaches the tissue cell death, tissue sloughing, and skin impairment
Venous Stasis Ulcers
• Signs and Symptoms:– Most significant sign is the ulceration– Skin will be darkened around ulcerated area– Varying degrees of pain– If diabetic, may not have any pain– Edema– Pedal pulses often present
Venous Stasis Ulcers
• Medical Management– Focus on wound healing• The wound will not heal if the skin continues to
be stretched• Use TED hose or ACE wrap and elevate the legs
whenever possible– Treatment of infection if needed– Nutrition with adequate protein
Venous Stasis Ulcers
• Medical Management cont.– Debridement of necrotic tissue if needed– Unna’s paste boot– Protective boot that can be left on for 1-2 weeks• (next slide)
Unna’s Boot is a medicated bandage that provides gradient compression therapy for controlling venous ulcers, venous insufficiencies, and other minor orthopedic problems. The bandage is permeated with zinc oxide and calamine to comfort the skin. Unna’s Boot is commonly used for active patients who are not confined to a wheelchair or bed. Unna’s Boot comes in the form of a non-raveling gauze that will mold evenly to the applied limb. Once applied, the bandage forms a semi-rigid cast that provides high working pressure and a lower resting pressure. This is ideal for patients who actively walk around and would like to preform normal daily activities. The 100% cotton base reduces wastage and the calamine prevents skin irritation. Depending on the amount of drainage from the ulcer, Unna’s Boot is usually kept in place for 3-7 days. A self-adherent wrap can also be wrapped around Unna’s Boot for extra support.
Varicose Veins
Varicose Veins
• Tortuous dilated vein with incompetent valves• Usually in lower extremities• Higher incidence in women aged 40-60• Risk: family tendency, congenital
abnormalities, pregnancy, obesity, constrictive clothing, and prolonged standing
Varicose Veins
• Pathophysiology– Incompetent valves Veins lose elasticity– Relatively weak vessel walls (compared to arteries)
Unable to support the increased pressure of the blood within the vessel Vein dilates as blood in it flows backward
Varicose Veins
• Signs and Symptoms:– Vary according to area of varicosity– May appear as darkened areas on the surface of
the skin– May experience dull aches, fatigue, cramping,
heaviness of legs– May shows sign of venous stasis
Varicose Veins
• Data Collection:– Subjective• Assessment of risk factors– Family hx, pregnancy
• Aches, cramping, fatigue, heaviness, pain
– Objective• Inspecting for varicosities• Inspecting for ulcerations
Data Collection
• Trendelenburg’s test: Evaluates the filling time of veins to assess for incompetent valves• Pt. lies down with the affected leg raised to allow for
venous emptying• A tourniquet is applied above the knee• Pt. stands• The direction and filling time of the veins are recorded
before and after the tourniquet is removedWhen the veins fill rapidly from a backward blood flow, the
veins are determined to be incompetent
Varicose Veins
• Medical Management:– TED hose– Rest and leg elevation– Sclerotherapy may be used for cosmetic purposes– Vein ligation and stripping may be used in severe
cases
Varicose Veins
• Nursing Interventions:– Analgesics for discomfort– Regular exercise– Leg elevate 6-10 inches on small stool if tendency
to get varicose veins– Frequent position changes not standing in one
spot for extended time
Varicose Veins
Nursing Interventions: cont.– Teach about applying support hose after legs have
been elevated for an extended time (10-15 minutes)
– Do not fold or roll hose down– Smooth hose and avoid wrinkles– Remove hose daily, wash, dry, elevate legs above
the heart when in bed or feet when sitting
Thrombophlebitis
Definitions
• Phlebitis: Inflammation in the wall of a vein without clot formation
• Thrombophlebitis: formation of a clot in a vessel, typically a superficial vein, with associated inflammation
• Thrombosis: formation of a clot in a vessel• Thrombus: a formed clot that remains at the site
where it formed • Embolus: the thrombus moves distally to another
anatomic location
Superficial Thrombophlebitis
• Inflammation of a vein and formation of a thrombus
• Women may be more susceptible• Risk factors include– Venous stasis– Hypercoagulability– Trauma to blood vessel wall
Thrombophlebitis (superficial)
• Signs and Symptoms:– Pain, edema in affected area– Red streak over a vein– Erythema, warmth, and tenderness along course
of the vein– Circumference of calf or thigh may increase
Thrombophlebitis (superficial)
• Subjective: – c/o pain in affected extremity– Note hx. of venous disorders
• Objective: inspect the extremity for:– Color– Temperature– Leg circumferences– Upper body venous congestion
Thrombophlebitis
• Medical Management:– Superficial thrombophlebitis• Moist heat to improve circulation• Elevation of legs to improve venous return• NSAIDs
Deep Vein Thrombosis
• Deep vein thrombosis (DVT) occurs in larger, deep veins and can be threatening to life and limb
• Mortality primarily due to risk of pulmonary embolism
DVT Signs and Symptoms
• Warm, tender, unilateral edema• May not have symptoms• Unilateral leg pain, tightness, discomfort• Positive Homan’s sign– Pain with dorsiflexion of the foot– Only appears in 10% of patients
Diagnostics for Deep Vein Thrombosis
• Ultrasound duplex scan is most widely used
• D-dimer blood test – normally undetectable; level is ↑ once a clot is in the process of being broken down
Prevention of DVT
• Early ambulation in the hospital• Low molecular weight heparin or
subcutaneous heparin– Lovenox 30 mg – 40 mg SubQ Daily– Heparin 5,000- 10000 units SubQ Q12 hr
• TED hose• Pneumatic compression stockings or boots
DVT Assessment• Subjective/Objective:– Ask client about recent injury– Is the affected area tender to touch– History of clots– Check for chest pain, dyspnea, tachycardia or
hemoptysis– Assess skin for redness, tenderness, hardness or
warmth, and Homan’s sign– Measure both legs at baseline
Treatment of DVT
• Anticoagulation with IV heparin or SubQ Lovenox (1 mg/Kg) until PT/INR is therapeutic on coumadin
• Long-term anticoagulation with coumadin (or other newer meds on the market)
• In patients who cannot be anticoagulated, consider Inferior Vena Cava (IVC) Filter to prevent Pulmonary Embolus (PE)
Complications of DVT
• Pulmonary embolus– Most likely cause of death in DVT– Sudden severe pleuritic chest pain, dyspnea,
tachypnea– Treatment• Anticoagulation• Fibrinolytic therapy for large, hemodynamically
significant PE• IVC Filter to prevent recurrent PE in patients who
cannot be anticoagulated• Surgical Thrombectomy
DVT Nursing Management
• Bed rest and elevation of the leg• Do not massage leg• Prevention is best way to treat• NURSE: Monitor vitals, IV sites, measure
circumference of affected leg, assess for s/s of embolization
• Assess for signs of bleeding if on anticoagulants• Remove elastic support or pneumatic compression
daily for hygiene.