Discover the power ofwater-soluble Turmerosaccharides TM

There is more to Turmericthan just Curcuminoids

Turmacin ® is an innovative clinically researched and patented ingredient that brings the joint and cartilage health benefits of

turmeric to dietary supplements. Featuring water-soluble Turmerosaccharides™, the bioactive polysaccharides.

Turmerosaccharides™ are a group of water-soluble bioactive polysaccharides present in Turmeric (Curcuma longa), which are

responsible for its joint health supporting properties.

GRAS for Turmacin® : Applications in Food and Beverages

Turmacin® can be used as a food ingredient in beverages (non-alcoholic), candies (including gummies, chews, etc), and bakery products (includes breakfast bars) at levels of 50 mg/serving.

Turmacin® : Recommended Dose: 500 mg twice a dayUses: Supports joint health*

New Clinical Trial: E�ect of Turmacin® onexercise-induced pain in healthy volunteers

Safety and e�cacy of Turmacin® in jointhealth — a randomised placebo-controlled trial

Turmacin® e�ectively supports joint health.It is safe and well tolerated*.

Standardized to TurmerosaccharidesTM ; the bioactive polysaccharides

Naturally bio-available

Self-a�rmed GRAS(application in food and beverages)

Wide range of formulations possible

Aqueous-based extract with clean label

Sustainable supply chain

Can be combined with curcumin forholistic turmeric benefits

Turmacin® supports management ofexercise-induced pain from day 5*.

Why Choose Turmacin® ?

083/TN/AT/08-19

Clinically tested for joint health

*Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

© 2019 Natural Remedies. All Rights Reserved.

Want to know more? hhp@naturalremedy.com www.naturalremedy.comIndia: Natural Remedies

54.97

57.23

27.14#

34.92

47.9

58.3

52.23

44.17

36.67#

60

50

40

30

WO

MA

C sc

ore

20Baseline

Turmacin ® 1g

Day 21 Day 42

Placebo Glocosamine

0

-10

10

Day 5

20

30

40

Turmacin® 1g PlaceboTurmacin® 0.5g

Day 7

1921 23

25

2624

Day 28 Day 56 Day 84

3830

3833

- 4 - 6

Perc

enta

ge o

f Pai

n Re

duct

ion

#Significantly di�erent (p<0.05) from placebo#Significantly di�erent (p<0.05) from placebo;

Turmacin® decreases ageing of cartilage cells in vitro (mediated by H2O 2, a free radical generator)

Turmacin® reduces cartilage degradation markers (IL-6, IL-8, COX-2, PGE2, TNF-α, ICAM-1) in chondrocytes in vitro

Turmacin® has been found to increase the gene expression of type II collagen and decrease the gene expression of MMP-3 and MMP-7 in animal studies

Turmacin® reduces NF-kB (a protein complex that plays a central role in inflammation) in vitro

Turmacin® : Multiple Modes of Action

110.24

WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index

55

45

35

25

Non-staining of equipment