diagnostics. hematology laboratory work-up normaljune 23, 2010remarks wbc4-11 x 10 9 /l8.08 x 10 9...
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Diagnostics
HEMATOLOGYLaboratory Work-Up
Normal June 23, 2010 Remarks
WBC 4-11 x 10 9/L 8.08 x 10 9/L NORMAL
RBC 4-6 x 10 9/L 4.82 x 10 9/L NORMAL
Hgb 120-180g/L 142g/L NORMAL
Hct 0.370-0.540% 0.431% NORMAL
MCV 80-100fL 89.4fL NORMAL
MCH 27-31pg 29.5pg NORMAL
MCHC 320-360g/L 329g/L NORMAL
RDW-CV 150-450 x 10 9/L 129 x 10 9/L REDUCED
Platelets 2-4 x 10 11/L 3.1 x 10 11/L NORMAL
Neutrophil 0.5-0.7 0.764 SLIGHTLY ELEVATED
Lymphocytes 0.2-0.5 0.103 REDUCED
Monocyte 0.02-0.09 0.082 NORMAL
Eosinophil 0.0-0.06 0.047 NORMAL
Basophil 0.0-0.02 0.004 NORMAL
APTT 36.4 36.3 NORMAL
PT 12-15 seconds 12.5 seconds NORMAL
BLOOD CHEMISTRYLaboratory Work-Up
Normal June 23, 2010 Remarks
BUN 3.2-8.0 mmol/L 2.46 REDUCED
Creatinine 53.133 umol/L 71 ELEVATED
Sodium 135-145 mmol/L 137 NORMAL
Potassium 4.0-4.5 mmol/L 4.3 NORMAL
Calcium 2.12-2.75 mmol/L 2.41 NORMAL
Albumin 38-51 g/L 31 REDUCED
AST 0-34 U/L 50 ELEVATED
ALT 0-30 U/L 42 ELEVATED
Total Bilirubin 0-17.1 umol/L 5.90 NORMAL
Dir Bilirubin 0-3.42 umol/L 1.96 NORMAL
Ind Bilirubin 3.4-13.7 umol/L 3.94 NORMAL
Urate 0.13-0.44 mmol/L 0.31 NORMAL
URINALYSISLaboratory Work-Up
Normal June 23, 2010 Remarks
Color Yellow Light Yellow NORMAL
Transparency Clear Clear NORMAL
SG 1.016-1.022 1.025 NORMAL
Ph 4.6-6.5 6.0 NORMAL
Sugar (-) (-) NORMAL
Albumin (-) (-) NORMAL
RBC 0-2/hpf 4/hpf MICROSCOPIC HEMATURIA
WBC 0-5/hpf 2/hpf NORMAL
Casts 3/hpf
Bacteria (-) 1/hpf POSSIBLE INFECTION
Ketones +1 ELEVATED
MULTIPLE CONTIGUOUS AXIAL CT SCAN OF THE CHEST WITH IV CONTRAST
Imaging Studies
Imaging Results
Imaging Results
• Well defined lobulated pulmonary mass with irregular margin with eccentric calcifications at the superior basal segment of the left lower lobe
• <1cm pulmonary nodule at the posterior basal segment of the right lower lobe
• With either linear fibrosis or subsegmental atelectasis at the anterobasal segment of the left lower lobe
• Pleural thickening, left lung• Thoracic spondylosis
SURGICAL PATHOLOGYTissue Diagnosis
April 26, 2010
Metastatic poorly differentiated adenocarcinoma
AFB SPUTUMCulture
June 26, 2010
• Day 1: (-) AFB• Day 2: (-) AFB
Diagnosis
Working Diagnosis
Lung cancer, non-small cell (adenocarcinoma), stage 4, currently undergoing cobalt radiotherapy with possible malnutrition, kidney and liver damage. Rule out pulmonary TB.
• The results of the biopsy confirm that indeed, the patient has a malignant tumor in the lung
• The enlarged supraclavicular lymph nodes indicate that the patient’s cancer is in stage 4
SCLC vs. NSCLCSCLC NSCLC
Scant cytoplasm Abundant cytoplasm
Hyperchromatic nuclei w/ fine chromatin pattern
Pleomorphic nuclei w/ coarse chromatin pattern
Indistinct nucleoli Prominent nucleoli
Diffuse sheet of cells Glandular or squamous architechture
Pain when swallowing
Decreased food intake
Guconeogenesis
Muscle wasting
hypoalbuminemia
Elevated AST, ALP
Ketone body production