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CARDIOVASCULAR SYSTEM

1) Digitalisa) Increase

b) Increase

c)

d)

shockirdlillkfdCiftj!JIIIDJidllbaiiMdl'ing antibody

potassium

iDdreased ventrieularexclillmttythOuld be treated with

6) Digitalis is given to pati WithAF becau.:a) It decreases atrial excitabilitb) It decreases atrial contractilityc) It depresses the conductivity of AV node

d) All ofthe above

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7) Causes ofdigitalis toxicity include:

a) Intracellular calcium overload

b) Intracellular potassium overloadc) Increased

d) Increased c.4.........,uv

a)

b)

c)

d) They

13) The most

a) Combination

b) CHF with sinus

c) Chronic AF without

d) All of the above

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..

14) Digitalis induced tachyarrhythmia is aggravated by the following except:a) Thiazides

b) Intravenous calcium

c) Sympathomimetics

d) Lignocaine

15) Digitalis induced heart block is aggravated by the following except:a) Beta blockers

b) Alpha methyl dopa

c) Intravenous calcium

d) Cionidine

16) Digitalis plasma level is increased by the following except:a) Cholestyramine

b) Atorvastatinc) Erythromycin

d) Quinidine

17) Pulmonary edema of acute heart failure is treated by the following except:a) Intravenous furosemide

b) Intravenous dopamine

c) Intravenous morphine

d) Intravenous nitroglycerin

18) Amlodipine has the following characters except:a) It may cause lower limb edema

a) It is used in peripheral vascular disease

c) It may cause marked tachycardia

d) Itis used in treatment of hypertension

19) About calcium channel blockers, the following statements are true except:a) Verapamil can be used as anti-anginal drug

b) Nifedipine can be used in peripheral vascular diseases as Raynaud's disease

c) Verapamil can be used in treatment of AV blockd) Diltiazem is a myocardial depressant

20) All the following are true about calcium channel blockers except:a) Constipation is seen with verapamil

b) Nifedipine induces minimal changes inheart rate since it induces less

vasodilation than amlodipine

c) Flushing and ankle edema are seen with nifedipine

d) Heart failure may occur with diltiazem

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21) In combination therapy of CHF, the following are correct except:a) Beta blockers abolish the hyperkalemia induced by ACEisb) Both beta blockers and ACEis can reduce cardiac mortality

c) Digoxin improves the symptoms but does not reduce cardiac mortality

d) ACEis decrease digoxin toxicity by maintaining serum potassium level

22) A drug used in angina that consistently decreases the heart rate and canprevent vasospasticanginal attacks:

a) Nifedipneb) Nitroglycerin

c) Propranolol

d) Verapamil

23) In hypertension,calcium channel blockers have the following advantages

except:a) No metabolic side effectsb) No sexual dysfunction

c) Useful in patients with renal impairmentd) Useful in patients with heart failure

24) Nifedipine has the following characters except:a) It is used in ischemic heart diseaseb) It is used in hypertensionc) Itis used in Raynaud's disease

d) Itcan produce headache and lower limb edema

25) In hypertension with ischemic heart disease, the drug used i:a) Furosemideb) Atenolol c)

Diltiazem d)

Nifedipine

26) Verapamil can produce the following adverse effects except:

a) Diarrheab) Heart block

c) Bradycardia

d) Heart failure

27) Which of the following antihypertensive drugs has a favorable effect onplasma lipids:

a) Propranolol

b) Ramipril

c) Furosemide

d) Hydrochlorothiazide

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28) Compared to propranolol,atenolol has the following characters except:a) It is less likely to cause Raynaud's phenomena

b) It is safer in diabeticsc) It is less likely to produce bradycardia

d)It

is not useful in

30)1na)

b) 11/IJr:fiiiiMc) Tlll'"lWice.._....d) r.tM IIIIrlliiJtMikmiscullar

33)a)

b)c)

d) Pro

34) Thea) Captopril

b) Nifedipine

c) Verapamil

d) Ramipril

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----------------------------------------------------------------35) Thiazides can potentiate the following antihypertensives except:

a) Hydralazine

b) Amlodipine

c) Propranolol

d) Ramipril

36) The following

a) Captopril

b) Nifedipi

c) Vd) ...,..1"\..,..,

41) In nvrtertensuJ

a) Fosinopril

b) Lisinopril

c) Captopril

d) Ramipril

n be used is:

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42) In hypertension with liver disease, the ACEI that can be used is:a) Fosinopril

b) Lisinopril

c) Captopril

d) Ramipril

44}

a)

b)c)

d)

48) Advantagesa) no riskof

b) no risk of retoto

vC) no risk of renal

d) none of the above

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49) During treatment ofhypertension, the following statements are trueexcept:

a) Reserpine may cause depression due to dopamine deficiency

b) Alpha methyl dopa acts on peripheral alpha-2 adrenergic receptors

c) Thiazide diuretics may

d) Captopril can "'"..........

50) In bvtertenstoa) roJprartoto

b) caotoo

c)

d)

used

ve.

53)a)

b)

c)

d)

55) All ofthe

a) Clonidine.

b) a-methyl dopa.

c) Propranolol.

d) Amlodipine.

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56) An antihypertensive that improves diabetes in a hypertensive diabetic is:a) Hydrochlorothiazide.

b) Lismopril.

c) Atenolol.

d) None ofthe above.

58) An

a)

b)c)

d)

62) In

following benefits

a) Diuretics hypertensives

b) Diuretics antagonize with beta blockers

c) Diuretics neutralize the .

d) Beta blockers block the increased rennin level associated with diuretics

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63) In hypertension diuretics have the following advantages except:

a) They are the least expensive

b) They reduce cardiovascular complications

c) They have minimal metabolic side effects

d) They reduce mortality

64) Beta blockers caJUl.JC. tllrMIIIIIR. a) Inhibition of :nile8seb) Reduction cantiacou&putc) Direct v donc) Inhibit' n ofcentralsympatheticdischarge

65) All t

hypertedllill u.....,. o:

a) Rilmellddilrte

owing except:

69) In combina statements

iscorrect:a) Beta blockers by nifedipine

b) Beta blockers abolish the induced by thiazides

c) Beta blockers abolish the tachycardia induced by nifedipine d) Beta blockers abolish the metabolic side effects induced by thiazides

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70) Dyslipidemia can be a side eft:ect of:

a) Propranolol

b) Nifedipine

c) Amlodipine

d) foinopril

74)

a)1HCD eQPICPf..

b) Nf.llrtllll....,.... c)

d) ItliMi4111

76) Beta-adrenergic

a) Uncomplicated hyp

b) Hypertension with congestive

c) Hypertension with coronary heart diseased) Hypertension with high COP

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(B) Give Reason (s)

* ACEis may cause acute angioedema and chronic dry cough

* Ang10tensin-Il receptor blockers do l!Y-\"""""' 10e oema

*In elderly hypertensive va..l....._

*Diuretics are combiuc;\,J,

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*Digoxin bioavailability is decreased.by cholestyramine

* Verapamil can elevate plasma level of digoxin

*Digoxin is contraindicated in WPW

*

*I

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(C) Complete

* Combined with ACEis in

* Angiotensm-II Receptor B.v"'-

of . .........., so they

.

..........

* In treatment of

monotherapy

*

* In yplftelll8i,,epatients with peripheral vascular diaeaae.we can Ole .. or

_.,._mtrliDdilted as theymay proctaie ..........I

*

with pregnancy.

* Regarding ACEis,...... is preferred in

preferred in renal diseases

* ...................is a selective arteriodilator which can cause SLE.

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* Withdrawal of...... after prolonged used may cause rebound

hypertensive crisis due to increased sympathetic activity

* The main risk resulting from the use of ACEis with spirolactone or beta

blockers is ......

*The drugs used in HF to reduce CV mortality are ........, ........, .......

*.......is the drug of choice in hypertensive emergency inpregnancy

* Serum Ca level is increased by ...... diuretics and decreased by .......

diuretics

* Serum K level is increased by ...... diuretics and decreased by .......

diuretics

* ...... is a selective alphal and nonselective beta blocker used mainly

i.v. in hypertensive emergencies

* ......is a selective alphal and nonselective beta blocker that can be

used in heart failure

*......... is a beta blocker having alpha blocking activity & is used in\

management of hypertension due to pheochromocytoma

* Digitalis ....... conduction in AV node*Digoxin acts by inhibiting .................. enzyme hence

.................... intracellular calcium

*ACEis may cause persistent dry cough due to accumulation of ........in

the lung

60