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CURRICULUM VITAE2015/06/11 revised

NAME: Shin-Cheh Chen

SEX: Male

DATE OF BIRTH: February 12, 1951

CITIZENSHIP: Chinese

LANGUAGES: Chinese, English

HOME ADDRESS: 344-1,7th floor, Fu-Jin Street, Taipei, 105, TaiwanRepublic of China

OFFICE ADDRESS: 199, Tung Hwa North Road, Taipei, 105, Taiwan, Republic of ChinaTel. No.: (02) 2713-5211 Ext. 3141FAX: (02) 2719-68305, Fu-Shing ST., Kuei-Shan, TaoYuan, TaiwanTel. No.: (03)3281200 Ext. 3219

E-mail address: chensc@adm.cgmh.org.tw

EDUCATION: Taipei Medical College (1970-1977)

ACADEMIC APPOINTMENT:

1. Attending Staff, Division of General Surgery, (1984-Now) Chang Gung Memorial Hospital

2. Chief, Breast Surgery division, Lin-Kou, CGMH (2002-Now)

3. Chief, Taipei Surgical Division, CGMH (1999-Now)

4. Director, Breast cancer Treatment Group (1999-Now)

5. Lecture, Chang Gung University (1994/4-2004/7)

6. Lecture, Department of Surgery, CGMH (2002/7-2003/6)

7. Assistant professor, Chang Gung University (2002-2004/7)

8. Assistant professor, Department of Surgery, CGMH (2003/7-2007/6)

9. Associate professor, Chang Gung University (2004/8-Now)

10. Associate professor, Department of Surgery, CGMH (2007/7-2014/06)

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11. Professor, Department of Surgery, CGMH (2014/7-Now)

12.Deputy Chairperson, Department of General Surgery, CGMH (2014/7-Now)

13.Member,Data Safety and Monitor Board, CGMH (2014/4-Now)

POST GRADUATE TRAINING:

1. Military Service, Navy (1977-1979)

2. Surgical Resident, Chang Gung Memorial Hospital (1979-1982)

3. Surgical Chief Resident, Chang Gung Memorial Hospital (1982-1983)

4. Surgical Fellow, Division of General Surgery, (1983-1984) Chang Gung Memorial Hospital

5. Attending Staff, Division of General Surgery, (1984-Now) Chang Gung Memorial Hospital

6. Clinical Observer, Memorial Sloan-Kettering Cancer Center, New York, U.S.A. (Apr. - Sept. 1987)

7. Clinical Observer, National Cancer Center, Tokyo, Japan (Oct. 1987)

LICENSURE:

1. Republic of China License No.: 007379

2. Board of Surgery, Republic of China No.: 1243

3. Board of Surgical Gastroenterology, Republic of China No.: 043

4. Board of Breast Cancer, Taiwan No: 0007

PROFESSIONAL AFFILIATIONS:

1. Surgical Association, Republic of China

2. Formosan Medical Association

3. The Gastroenterological Society of the Republic of China

4. Member, Collegium Internationale Chirurgiae Digestivae

5. Executive member, The Society of the Ultrasound in Medicine, Republic of China

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6. Surgical Society of Gastroenterology, Republic of China

7. International College of Surgeons, Republic of China

8. President, The Breast Cancer Society of Taiwan (2008 ~ 2010)

9. Active member, American Society of Clinical Oncology (1995 ~ now)

10.台灣外科醫學會第20屆教育委員(educational commissioner of Taiwan Surgical Association)

11.癌症希望協會學術委員(study commissioner of HOPE SOCIETY for CANCER

CARE)

12.行政院衛生署國民健康局癌症診療品質認證委員(certified commissioner of cancer diagnostic quality of Health Promotion Administration, Ministry of Health and Welfare) (2009/02/02-now)

13. President, Taiwan Society of Ultrasound in Medicine (2010 ~2012)

14. Honor President, Taiwan Society of Ultrasound in Medicine (2012 ~now)

PROFESSIONAL ACITIVITY:

Member, Tumor Committee, CGMH (1988-now)

Director, breast cancer study group, CGMH (1999-now)

RESEARCH INTEREST:

1. Surgical oncology.

2. Breast Surgical oncology.

A. About Breast Disease: 1. J.L. Kao, S.C. Chen, M.F. Chen: Breast cancer and pregnancy. Medicine Today

18:463-466, 1991.

2. S.C. Chen , M.F. Chen: Comparison of X-ray and ultrasonic mammography in breast lesions. Medicine Today 18:692, 1991.

3. S.C. Chen, et al: Prognostic factors in breast cancer - application of flow cytometry. Medicine Today 18:749-753, 1991.

4. S.H. Ng, S.C. Chen, et al: Mammography of breast carcinoma: experience of 108 cases. J Formosan Med Assoc 90:541-546, 1991.

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5. S.C. Chen , M.F. Chen, et al: 長期服用 Tamoxifen之爭議。Medicine Today 18:952-955, 1992.

6. S.C. Chen , M.F. Chen: 早期乳癌病人是否應接受輔助治療。 Medicine Today 18:984-988, 1991.

7. S.C. Chen , M.F. Chen, et al: Ultrasonic and X-ray mammography in young women with breast lesions. J Surg Assoc, ROC 25:963-967, 1992.

8. H.M. Chen, S.C. Chen, et al: Surgical treatment of phyllods tumor of the breast – review of the clinico-pathologic features. J Surg Assoc, ROC 26:1974-1978, 1993.

9. SC Chen , TL Hwang, MF Chen:Intraoperative ultrasound-guided excisional biopsy for nonpalpable breast lesions.J Surg Assoc, ROC 30:389-393, 1997.

10. Chen SC , Chao TC, Hwang TL, Jeng LB, Jan YY, Wang CS, Chen MF, Hsueh S, Tsao KC, Sun CF:Prognostic factors in node-negative breast cancer patients: the experience in Taiwan.The Chang Gung Med J 21:363-370, 1998.

11. Chen SC , et al:Timing of shoulder exercise after axillary lymphadenectomy for breast cancer: a prospective study.The Chang Gung Med 22:37-43, 1999.

12. Chao TC, Lo YF, Chen SC, Chen MF:Prospective sonographic study of 3093 breast tumors.J Ultra Med 18:363-370, 1999.

13. Chao TC, Lo YF, Chen SC, Chen MF:Color doppler ultrasound in benign and malignant breast tumors.Breast Cancer Research and Treatment 57:193-199, 1999.

14. Chao TC, Wang CS, Chen SC, Chen MF:Metaplastic carcinomas of the breast. J Surg Oncology 71:220-225, 1999.

15. Wang YL, Cheung YC, Hsueh S, Lui KW, Tseng JH, Yeow KM, Chang HK, Chen SC, Chen MF:Automated sterotaxic core needle biopsy of breast lesions.Chinese J Radiology .24:95-99, 1999.

16. Y.F. Lo, T.C. Chen, S.C. Chen, C.C.-k. Chao: Aberrant expression of TSG101 in Taiwan Chinese breast cancer. Breast Cancer Research and Treatment 60:259-266,2000.

17. Y.C. Cheung, S.C. Chen, K.F. Lee, Y. L. Wan, S.H. Ng: Sonographic and Pathologic Findings In Typical and Atypical Medullary Carcinomas of the Breast-Journal of Clinical Ultrasound 2000;28:p.325-331 (SCI).

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18. Chao TC, Luo YF, Chen SC, Chen MF:Color Doppler ultrasound in breast carcinomas: Relationship with hormone receptors, DNA ploidy, S-phase fraction, and histopathology.Ultrasound in Medicine & Biology 2001;27:351-355.

19. Hsu JH, Tseng CS, Chen SC:A methodology for evaluation of boundary detection algorithms on breast ultrasound images. Journal of medical engineering & technology, 2001;25:173-177.

20. S.C. Chen, M.F. Chen, T.L. Hwang, T.C. Chao, Y.F. Lo, S. Hsueh, J.T.-C. Chang, W.M. Leung: Prediction of supraclavicular lymph node metastasis in breast carcinoma. Int. J. Radiation Oncology Biol. Phys. 2002;52:614-619.

21. Cheung YC, Wan YL, Chen SC, Lui Kw, Ng SH, Yeow KM, Lee KF, Hsueh S:Sonographic evaluation of mammographically detected microcalcifications without a mass prior to stereotactic core needle biopsy. Journal of clinical ultrasound, 2002;30:323-331.

22. Chao TC, Lo YF, Chen SC, Chen MF:Sonographic features of phyllodes tumors of the breast. Ultrasound Obstet Gynecol 2002;20:64-71.

23. Cheung YC, Su MY, Ng SH, Lee KF, Chen SC, Lo YF: Lumpy silicone-injected

breasts Enhanced MRI and Microscopic correlation.Journal of clinical imaging, 2002;26:397-404.

24. C.N.Yeh，S.C. Chen, T.L. Hwang, M.F. Chen, C.C. Liaw, H.L. Chan:Breast carcinoma in patients with dermatomyositis: a retrospective analysis of eight cases. The Chang Gung Med J 25:374-380, 2002.

25. Y.C. Cheung, S.C. Chen, M.F. Su, L.C.See, S. Hsuej, H.K. Chang, Y.C. Lin, C.S. Tsai:Monitoring the size and response of locally advanced breast cancers to neoadjuvant chemotherapy (weekly paclitaxel and epirubicin) with serial enhanced MRI. Breast Cancer Research and Treatment, 2003;78:51-58.

26. S.C. Chen, H.R. Yang, T.L. Hwang, M.F. Chen, Y.C. Cheung, S.Hsueh:Intraoperative ultrasonographically guided excisional biopsy or vacuum-assisted core needle biopsy for nonpalpable breast lesions.Annals of Surgery, 2003;238: 738-742.

27. S.C. Chen, Y.C. Cheung, C.H. Su, M.F. Chen, T.L. Hwang, S. Hsueh: Analysis of sonographic features in differentiation of benign and malignant breast tumors in various size groups.Ultrasound in Obstetrics & Gynecology, 2004;23:188-193.

28. S.C. Chen, Y.C. Cheung, Y.F. Lo, M.F. Chen, T.L. Hwang, C.H. Su, S. Hsueh:

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Sonographic differentiation of invasive and intraductal carcinomas of the breast.The British Journal of Radiology, 2003;76:600-604.

29. Y.C. Lin, S.C. Chen, S. Hsueh, Y.F. Lo, Y.H. Chow-Wu, I C. Liaw, A.J. Cheng:Lack of correlation between expression of human mammaglobin mRNA in peripheral blood and known prognostic factors for breast cancer patients.Japanese Journal of Cancer Research, 2003;94:99-102.

30. Y.C. Cheung, Y.F. Lo, L.C. See, S.C. Chen, T.C. Chao: Hemodynamic parameters

by color Doppler ultrasound and dynamic enhanced magnetic resonance imaging in palpable T1 breast cancers.Ultrasound in Med. & Biol., 2003;29:881-886.

31. S.C. Chen, H.K. Chang, Y.C. Lin, W.M. Leung, J.T. Chang, Y.C. Cheung, s. Hsueh, Y.F. Lo, C.H. Su, M.F. Chen:Neoadjuvant chemotherapy with biweekly epirubicin and paclitaxel for locally advanced breast cancer. Proc. of ASCO 2003;No.231.

32. T.C. Chao, M.F. Chen, C.S. Wang, Y.Y. Jan, T.L. Hwang, S.C. Chen:Small invasive breast carcinomas in Taiwanese women. Annals of Surgical Oncology 2003;10:740-747.

33. T.C. Chao, Y.F. Lo, S.C. Chen, M.F. Chen: Phyllodes tumors of the breast. European Radiology 2003;13:88-93.

34. Y.C. Cheung, Y.L. Wan, Y.F. Lo, W.M. Leung, S.C. Chen (correspondence author), S. Hsueh: Preoperative magnetic resonance imaging evaluation for breast

cancers after sonographically guided core-needle biopsy: a comparison study. Annals of Surgical Oncology 2004;11:756-761.

35. Shin-Cheh Chen , James T. Wu: Review of Serum C-erbB2: An Noninvasive Test for Identification and Monitoring of Breast Cancer Patients for Herceptin Treatment. Focus on Breast Cancer Research ISBN: 1-59033-961-4 Editor: Andrew P. Yao, pp-107-130.

36. S.C. Chen , H.K. Chang, Y.C. Lin, Y.C. Cheung, C.S. Tasi, W.M. Leung, S.Hsueh, M.F. Chen: Increased feasibility of weekly epirubicin and paclitaxel as neoadjuvant chemotherapy for locally advanced breast carcinoma.Onkologie 2005;28:339-344.

37. Y.F. Lo, S. Hsueh, S.Y. Ma, S.C. Chen, M.F. Chen: Clinical relevance of nonvisualized sentinel lymph nodes in unselected breast cancer patients during lymphoscintigraphy. Chang Gung Med J 2005;18:378-386.

38. C.F. Huang, M.H. Cheng, H.T. Chen, F.C. Wei, S.C. Chen, Y.F. Lo, T.S. Yeh, T.C. Chao: Skin-sparing mastectomy with immediate breast reconstruction

using Free deep inferior epigastric perforator flap. J Plast Surg Asso R.O.C.

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2004;13:244-252.

39. Y.C. Lin, S.C. Chen (correspondence author), H.K. Chang, S. Hsueh, C.S. C.S. Tsai, Y.F. Lo, T.L. Hwang, M.F. Chen: Identifying good prognosis group of breast cancer patients with 1-3 positive axillary nodes for adjuvant cyclophosphamide, methotrexate and 5-fluorouracil (CMF) chemotherapy. Jpn J Clin Oncol 2005;35:514-519.

40. Wen-Hung Kuo, Amy Ming-Fang Yen, Po-Huang Lee, Ming-Feng Hou, Shin-Cheh Chen, Kai-Mo Chen, Tony Hsiu-His Chen, King-Jen Chang:

Incidence and risk factors associated with bilateral breast cancer in area with early

age diagnosis but low incidence of primary breast cancer.Breast Cancer Research

and Treatment 2006;99:221-228.

41. Cheung YC, Chen SC, Hsieh IC, Lo YF, Tsai HP, Hsueh S, Yen TC: Multidetector computed tomography assessment on tumor size and nodal status

in patients with locally advanced breast cancer before and after neoadjuvant

chemotherapy .European Journal of Surgical Oncology 2006;32:1186-1190.

42. Chen SC , Chang HK, Lin YC, Leung WM, Tsai CS, Cheung YC, Hsueh S, See LC, Chen MF:Prognosis of breast cancer after supraclavicular lymph node

metastasis-not a distant metastasis. Annals of surgical oncology 2006; 13: 1457-1465 .

43.Grace Hui-Min Wu, Li-Sheng Chen, King-Jen Chang, Ming-Feng Hou, Shin-Cheh Chen, Tse-Jia Liu, Chiun-Sheng Huang, Giu-Cheng Hsu, Chih-Cheng Yu, Li-Li Jeng, Shou-Tung Chen, Yi-Hung Chou, Chang-Ying Wu, Koong Shin-Lan and Tony Hsiu-His Chen for the Taiwan Breast Cancer Screening Group: Evolution of breast cancer screening in countries with intermediate and increasing incidence of breast cancer.J Med Screen 2006; 13 (Suppl 1):s23-S27.

44.Yung-Feng Lo, MD; Swei Hsueh, MD; Shih-Ya Ma, MD; Shin-Cheh Chen, MD;Miin-Fu Chen, MD: Radioguided Sentinel Lymph Node Biopsy in Early Breast Cancer: Experience at Chang Gung Memorial Hospital.Chang Gung Medical Journal 2006;29:445-454.

45. Joseph Tung-Chieh Chang, M.D., M.H.A., Shin-Cheh Chen, M.D. Yun-Chan Lin, M.D., Yuan-Chua Chen, M.D., Chien-Yu Lin, M.D., and Ann-Joy Cheng, P.H.D.:Health-related quality of life and patient satisfaction after treatment for breast cancer in northern Taiwan.Int. J. Radiation Oncology Biol. Phys. 69:49-53. 2007, Sep （SCI；IF=4.105；RADIOLOGY, NUCLEAR MEDICINE & MEDICAL

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IMAGING 12/166=7% ）46. Laio MN, Chen MF, Chen SC, Chen PL: Healthcare and support needs of women

with suspected breast cancer. Journal of Advanced Nursing 60(3), 289-298.2007 Nov. （SCI；IF=1.477；NURSING 12/99=12 %）

47. Shin-Cheh Chen, Hsien-Kun Chang, Yung-Chang Lin, Swei Hsueh, Yun-Chung Cheung, Wai-Man Leung, Chien-Sheng Tsai, Yung-Feng Lo, Hsiu-Pei Tsai,

Shih-Che Shen, Miin-Fu Chen.High Pathologic Complete Response in HER 2-positive Locally Advanced Breast Cancer after Primary Systemic Chemotherapy with Weekly Docetaxel and Epirubicin. JJCO 2008; 38: 99-105.（SCI；IF=1.783；ONCOLOGY 135/196= 69 %）

48. Hsiang-Ya Wang, Rozina S. Ali, Shin-Cheh Chen, Tzu-Chieh Chao, Ming Huei Cheng. One-Stage immediate breast reconstruction with implant following skin-sparing mastectomy in Asian patients.Annals of Plastic Surgery 2008;60:362-366. （SCI；IF=1.318；Surgery 104/199= 52%）

49. Laio MN, Chen MF, Chen SC, Chen PL: Uncertainty and Anxiety during the Diagnostic Period for Women with Suspected Breast Cancer.Cancer Nursing 2008;31:274-283. （SCI；IF=1.792；ONCOLOGY 133/196=68%）

50. Shin-Cheh Chen, Alex Yuang-Chi Chang: Optimizing the management of advanced breast cancer in the Asia-Pacific region: Role of clinical trials and treatment guidelines. Asia-Pacific Journal of Clinical Oncology 2008;4:s24-S29. （SCI；IF=0.585；ONCOLOGY 180/196=92%）

51. Kuan-Der Lee, Shin-Cheh Chen, Chunghuang Hubert Chan, Chang-Hsien Lu, Chih-Cheng Chen, Jen-Tsun Lin, Miao-Fen Chen, Shih-Hao Huang, Chun-Ming Yeh, Min-Chi Chen: Increased risk for second primary malignancies in women with breast cancer diagnosed at young age: a population-based study in Taiwan.Cancer Epidemiol Biomarkers Prev 2008;17(10):2647-2655. （SCI；IF=3.989；GASTROENTEROLOGY & HEPATOLOGY 14/74=18.9%）

52. Chun-Han Chen, MD; Yong-Feng Lo, MD; Hsiu-Pei Tsai, MD; Shih-Che Shen, MD; Tzu-Chieh Chao, MD, PhD; Miin-Fu Chen, MD; Shin-Cheh Chen*, MD (correspondence author): Low Body Mass Index is An Independent Risk Factor of

Locoregional Recurrence in Women with Breast Cancer Underwent Breast Conserving Therapy.Chang Gung Medical Journal 2009 Sep-Oct;32(5):553-62. (長庚醫誌)

53. Mei-Nan Liao, Ping -Ling Chen, Miin-Fu Chen, Shin-Cheh Chen, Yi-Hua Chen. Supportive care for Taiwanese women with suspected breast cancer during diagnostic period: effect on healthcare and support needs. Oncology Nursing Forum 2009;36:585-92.（SCI；IF=2.393；ONCOLOGY 107/196=54.6%）

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54. Cheng-Hung Lin M.D. , Rozina Ali M.D. , Shin-Cheh Chen M.D . , Chris Wallace M.D. , Yu-Chen Chang M.D. , Hung-Chi Chen M.D. , Ming-Huei Cheng M.D. Vascularized groin lymph node transfer using the wrist as a recipient site for management of postmastectomy upper extremity lymphedoma. Plast. Reconstr. Surg. 123:1265-1275, 2009. （SCI；IF=3.535；SURGERY 13/198=6.6%）

55.Cheung YC, Chen SC, Ueng SH, Ko SF, Wan YL.: Dynamic enhanced computed tomography values of locally advanced breast cancers predicting axilla nodal metastasis after neoadjuvant chemotherapy. J Comput Assist Tomo. May-Jun;33(3):422-5, 2009 （SCI；IF=1.582；RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING  62/120= 51.7%）

56. MN Laio, PL Chen, MF Chen, SC Chen: Effect of supportive care on the anxiety of

women with suspected breast cancer. Journal of Advanced Nursing 2010 Jan;66(1):49-59 (SCI；IF=1.685；NURSING 19/107=17.76 %）57. G. Capri, J. Chang, Chen SC. Chen, P. Conte, K. Cwiertka, G. Jerusalem, Z.

Jiang, S. Johnston, B. Kaufman, J. Link, J. Ro, J. Schütte, C. Oliva, R. Parikh, A. Preston, J. Rosenlund, M. Selzer, D. Zembryki and S. De Placido : An open-label expanded access study of lapatinib and capecitabine in patients with HER2-overexpressing locally advanced or metastatic breast cancer. Annals of Oncology. 2010;21:474-48（SCI；IF=6.578；ONCOLOGY 18/203=8.9%）

58. Marion Procter, Thomas M. Suter, Evandro de Azambuja, Urania Dafni, Veerle van Dooren, Susanne Muehlbauer, Miguel Angel Climent, Ernst Rechberger, Walter Tsang-Wu Liu, Mazakasu Toi, R. Charles Coombes, David Dodwell, Olivia Pagani, Jorge Madrid, Marcia Hall, Shin-Cheh Chen, Christian Focan, Michael Muschol, Dirk J. van Veldhuisen, Martine J. Piccart-Gebhart : Longer-Term Assessment of Trastuzumab-Related Cardiac Adverse Events in the Herceptin Adjuvant (HERA) Trial .J Clin Oncol. 2010 Jul 20;28(21):3422-8.（SCI；IF=17.96；ONCOLOGY 5/203=2.6%）

59. Li-Ni Liu, Christine Miaskowski, Joung-Shyan Wang, Shin-Cheh Chen, Mei-Ling Chen. Accuracy of body mass index to determione obesity in women with breast cancer: An observational study of Taiwanese sample. International Journal of Nursing Studies 2010;47:994-1000. (SCI；IF=2.248；NURSING 3/107=2.8%)

60.Shih-Che Shen, Chien-Hung Liao, Yung-Feng Lo, Hsiu-Pei Tsai1, Wen-Lin Kuo1,Chi-Chang Yu1, Tzu-Chieh Chao, Miin-Fu Chen, Hsien-Kun Chang, Yung-Chang Lin, Wen-Chi Shen, Shir-Hwa Ueng, Li-Yu Lee, Swei Hsueh, Yi-Ting Huang, Shin-Cheh Chen*, (correspondence author).Favorable Outcome of Secondary Axillary Dissection in Breast Cancer Patients with Axillary Nodal Relapse, Annals of Surgical Oncology, 2012;19:1122-8. (SCI；IF=3.94；ONCOLOGY 54/203=26.6%)

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61. Pei-Ching Huang, MD; Yun-Chung Cheung, MD; Yung-Feng Lo1, MD, Shin-Cheh Chen1, MD; Tzu-Chieh Chao1, MD; Shir-Hwa Ueng, MD; Swei Hsueh, MD; Mei-Hua Chang, BS; Shu-Hang Ng, MD. A Comparison of Spring-loaded and Vacuum-assisted Techniques for Stereotactic Breast Biopsy of Impalpable Microcalcification Lesions: Experience at Chang Gung Memorial Hospital at Linkou.Chang Gung Med J 2011;34:75-83. (長庚醫誌)

62. YT Huang, YC Cheung, YF Lo, SH Ueng, WL Kuo, SC Chen. MRI findings of cancers preoperatively diagnosed as pure DCIS at core needle biopsy. Acta Radiol 2011;52:1064-8 (SCI；IF=1.350；RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 80/122=65.57%)

63. Mei-Ling Chen, Christine Miaskowski, Li-Ni Liu, Shin-Cheh Chen. Changes in perceived attentional function in women folloeing breast cancer surgery. Breast Cancer Res Treat 2012;131:599-606. (SCI；IF=4.198；ONCOLOGY 49/203 =24.1%)

64. Hsiu-Pei Tsai, Shin-Cheh Chen,Huei-Tzu Chien,Yi-Yin Jan,Tzu-Chieh Chao,Miin-Fu Chen,Ling-Ling Hsieh. Relationships between serum HER2 ECD,TIMP-1 and clinicaloutcomes in Taiwanese breast cancer. World Journal of Surgical Oncology 2012;10:42 (SCI；IF=1.200；ONCOLOGY 171/203=84.2%)

65.MN Liao, SC Chen, SC Chen, Lin YC, YH Hsu, HC Hung, Wang CH, Chen MF,Jane SW. Changes and predictors of unmet supportive care needs in Taiwanese women with newly diagnosed. Oncol. Nursing Forum 2012;39:E380-389 (SCI； IF=2.830；NURSING 1/107=0.93%)

66.CL Chen, MN Liao, SC Chen, PL Chan, SC Chen . Body Image and Its Predictors in Breast Cancer Patients Receiving Surgery. Cancer Nursing 2012;35: E10-E16 (SCI；IF=1.931；NURSING 8/107=7.5%)

67. Shin-Cheh Chen, Hsien-Kun Chang, Yung-Chang Lin, Swei Hsueh, Shir-Hwa Ueng, Shih-Che Shen, Wen-Lin Kuo Chi-Chang Yu, Yi-Ting Huang, Ting-Shuo Huang. Long-term Outcomes after Selective Neck Dissection for Breast Cancer Patients with Supraclavicular Nodal Metastasis. Ann of Surgery ( 2014 submitted)

68.Chi-Chang Yu, Kun-Chun Chiang, Wen-Lin Kuo, Shih-Che Shen, Yung-Feng Lo, Shin-Cheh Chen*(Corresponding author). Low re-excision rate for positive margins in patients treated with ultrasound-guided breast-conserving surgery. Breast 2013 ; 22, 698-702 (SCI；IF=2.581；Oncology  111/203=55%)

69. Shir-Hwa Ueng , Shin-Cheh Chen, Yu-Sun Chang, Swei Hsueh, Yung-Chang Lin, Hui-Ping Chien, Yun-Feng Lo, Shih-Che Shen, Chuen Hsueh. Phosphorylated mTOR expression correlates with poor outcome in early-stage

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triple negative breast carcinomas. International Journal of Clinical and experimental pathology 2012;5:806-813 (SCI；IF=2.0502；Pathology 38/76=50%)

70. Kun-Chun Chiang, Chun-Nan Yeh, Shin-Cheh Chen, Shih-Che Shen, Jun-Te Hsu, Ta-sen Yeh, Jong-Hwei S. Pang, Li-Jen Su, Masashi Takano, Atsushi Kittaka, Horng-Heng Juang, Tai C. Chen.MART-10, a New Generation of Vitamin D Analog, Is More Potent than α,25-Dihydroxyvitamin D3 in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells. Evidence-Based Complementary and Alternative Medicine 2012, Article ID 310872, 10 pages (SCI；IF=2.175；Integrative & complementary Medicine 6/22=27.3%)

71.Ming-Huei Cheng ,Shin-Cheh Chen, Steven L. Henry, Bien Keem Tan, Miffy Chia-Yu Lin,M.Sc.Ju-Jung Huang. Vascularized Groin Lymph Node Flap Transfer for Postmastectomy Upper Limb Lymphedema: Flap Anatomy, Recipient Sites, and Outcomes. Plast. Reconstr. Surg.2013;131:1286-1298 (SCI；IF=3.328； Surgery 19/204=9.3%)

72. Kuan-Liang LiU, Jen-Shi Chen, Shin-Cheh Chen , Pao-Hsien Chu.Cardiovascular Toxicity of Molecular Targeted Therapy in Cancer Patients: A Double-Edged Sword. Acta Cardiol Sin 2013;29:295-303 (SCI；IF=0.845；Cardiac & Cardiovascular system 107/125=85.6%)

73. Mei-Nan Liao, Shin-Cheh Chen , Yung-Chang Lin , Miin-Fu Chen , Chao-Hui Wang , Sui-Whi Jane . Education and psychological support meet the supportive

care needs of Taiwanese women three months after surgery for newly diagnosed breast cancer: A non-randomised quasi-experimental study. International Journal  of Nursing Studies 2014;51:390-399 (SCI；IF=2.248；NURSING 3/107=2.8%)

74. Mei-Nan Liao, Shu-Ching Chen, Shin-Cheh Chen ,Yung-Chang Lin , Miin-Fu Chen , Chao-Hui Wang,Ya-Hui Hsu,Hsueh-Chih Hung , Sui-Whi Jane. Change and predictors of symptom distress in breast cancer patients following the first 4 months after diagnosis. Journal of the Formosan Medical Association 2013 in pres s (SCI:, IF=1.695, Medicine, General& Internal 57/156=36.54%)

75.Kun-Chun Chiang, Shin-Cheh Chen, Chun-Nan Yeh, Jong-Hwei S. Pang,Shih-Che Shen, Jun-Te Hsu, Yu-Yin Liu, Li-Wei Chen, Sheng-Fong Kuo,Masashi Takano, Atsushi Kittaka, Chi-Chin Sun, Horng-Heng Juang, Tai C. Chen. MART-10, a less calcemic vitamin D analog, is more potent than1α ,25-dihydroxyvitamin D3in inhibiting the metastatic potentialof MCF-7 breast cancer cells in vitro. Journal of Steroid Biochemistry & Molecular Biology 2014;139:54– 60(SCI:, IF=4.049, Biochemistry & Molecular Biology 82/291=28.2%)

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76.Ta-Chung Chao, Dar-Ren Chen, Tsu-Yi Chao, Shin-Cheh Chen, Dah-Cherng Yeh, Hwei-Chung Wang, Wen-Tsung Huang, Kun-Ming Rau, King-Jen Chang, Tseng-Long Yang, Kuan-Der Lee,Cheng-Jeng Tai, Ling-Ming Tseng ,Ming-Feng Hou. Quality of life assessment in taiwanese patients with bone metastases from breast cancer receiving zoledronic acid. Anticancer research.2013;33: 5543-5548 (SCI:, IF=1.872,Oncology,145 /203=71.4%)

77. Hsiu-Hsiang Chen, Mai-Wei Lin,Wan-Ting Tien, Chin-Pen Lai, Kuo-Yao Weng, Ching-Huai Ko, Chun-Chuan Lin, Jyh-Chern Chen, Kuo-Tung Tiao, Tse-Ching Chen, Shin-Cheh Chen, Ta-Sen Yeh, Chieh-Fang Cheng. High-purity separation of cancer cells by optically induced dielectrophoresis. Journal of Biomedical Optics. Accepted March 14, 2014 (SCI:, IF=2.752, Biochmedical Research Methods, 30/78=38.46%)

78. Chiao-En Wu, Shin-Cheh Chen, Yung-Chang Lin, Yung-Feng Lo, Swei Hsueh ,Hsien-Kun Chang. Identification of Patients with Node-negative, Triple-negative Breast Cancer who Benefit from Adjuvant Cyclophosphamide,Methotrexate, and 5-Fluorouracil Chemotherapy. ANTICANCER RESEARCH 2014;34: 1301-1306 . (SCI:, IF=1.872,Oncology,145 /203=71.4%)

79.Li-Fen Chao , Ketan M. Patel , Shin-Cheh Chen ,Hung-Bun Lam , Chia-Yu Lin, Hsueh-Erh Liu ,Ming-Huei Cheng. Monitoring patient-centered outcomes through the progression of breast reconstruction: a multicentered prospective longitudinal evaluation. Breast Cancer Res Treat 2014; 146:299–308 (SCI；IF=4.198； ONCOLOGY 49/203 =24.1%)

80. Kun-Chun Chiang, Chun-Nan Yeh, Li-Chuan Chung, Tsui-Hsia Feng, Chi-Chin Sun, Miin-Fu Chen,Yi-Yin Jan, Ta-Sen Yeh, Shin-Cheh Chen ＊ & Horng-Heng Juang＊.WNT-1 inducible signaling pathway protein-1 enhances growth and tumorigenesis in human breast cancer. SCIENTIFIC REPORTS 5 : 8686 DOI: 10.1038/srep08686 (SCI；IF=5.078； MULTIDISCIPLINARY SCIENCES   5/55 =9.1%)

81. Chi-Chang Yu, Shir-Hwa Ueng, Yun-Chung Cheung, Shih-Che Shen, Wen-Lin

Kuo, Hsiu-Pei Tsai, Yung-Feng Lo, Shin-Cheh Chen ☒. Predictors of Underestimation of Malignancy after Image-Guided Core Needle Biopsy Diagnosis of Flat Epithelial Atypia or Atypical Ductal Hyperplasia. The Breast Journal, 2015 1–9

Chen SC-13

B. Others:

1. S.C. Chen, C.R. Chang, J.J. Wang, H.A. Fang: Appendico-coli fistula - cases report. The Chang Gung Med J 6:238-241, 1983.

2. S.C. Chen, M.F. Chen, C.S. Wang: Mirizzi syndrome, 3 cases report. J Surg Assoc, ROC 17:279-283, 1984.

3. S.C. Chen, M.F. Chen: Indication and outcome of hepatic vein portal vein ligation. Medicine Today 11:20-23, 1984.

4. M.F. Chen, F.F. Chou, C.S. Wang, Y.Y. Jan, J.B. Jeng, C.W. Chen, T.K. Hwang, S.C Chen: Hepatectomy for intrahepatic stone. The Chang Gung Med J 9:145-149, 1984.

5. M.F. Chen, F.F. Chou, C.S. Wang, Y.Y. Jan, L.B. Jeng, C.W. Chen, T.L. Hwang, S.C. Chen, CC Tsai, RJ Lee: Surgery for spontaneous rupture of hepatocellular carcinoma - on particular reference to the transcatheter hepatic arterial embolization followed by hepatic resection. The Chang Gung Med J 8:1-6, 1985.

6. H.Y. Chen, M.F. Chen, C.S. Wang, Y.Y. Jan, T.L. Hwang, S.C. Chen:

Pancreatic injury.Chang Gung Med J 8:224-230, 1985.

7. T.L. Hwang, S.C. Chen, L.B. Jeng, Y.Y. Jan, C.S. Wang, M.F. Chen: Free perforation of marginal ulcer. J Surg Assoc, ROC 19:343-347, 1986.

8. T.C. Chao, M.F. Chen, S.C. Chen, et al: Experience in surgical treatment of pancreatic abscess. J Surg Assoc, ROC 21:251-257, 1988.

9. S.C. Chen, M.F. Chen, T.L. Hwang, C.W. Chen, J.B. Jeng, Y.Y. Jan, C.S. Wang, F.F. Chou: Biliary pancreatitis. J Surg Assoc, ROC 21:174-180, 1988.

10. M.F. Chen, Y.Y. Jan, C.S. Wang, L.B. Jeng, T.L. Hwang, S.C. Chen: Intrahepatic stones associated with cholangiocarcinoma. Am J Gastroenterol 84:391-395, 1989.

11. J.F. Fang, T.L. Hwang, C.S. Wang, S.C. Chen, L.B. Jeng: The treatment of esophagojejunal anastomotic stricture after total gastrectomy.

Chen SC-14

The Chang Gung Med J 12:148-155, 1989.

12. C.S. Chen, S . C . Chen , et al: Subcapsular hematoma of spleen - a complication following extracorporeal shock wave lithotripsy for ureteral calculus. The Chang Gung Med J 15:215-219, 1992.

13. C.C. Wang, S . C . Chen , et al: Successful embolectomy for acute mesenteric artery occlusion. The Chang Gung Med J 16:71-74, 1993.

14. L.B. Jeng, S . C . Chen , et al: Liver transplantation for a hepatitis B-related cirrhotic patient. J Formosan Med Assoc 92:267-273, 1993.

15. J.F. Fang, S . C . Chen , et al: Surgical treatment and outcome of blunt duodenal trauma after delayed diagnosis. J Surg Assoc, ROC 26:1545-1550, 1993.

16. M.F. Chen, Y.Y. Jan, C.S. Wang, T.L. Hwang, L.B. Jeng, S . C . Chen , T.J. Chen: A reappraisal of cholangicarcinoma in patient with hepato lithiasis. Cancer 71:2461-2465, 1993.

17. L.B. Jeng, C.H. Hsu, C.C. Wang, R.J Chen, S . C . Chen , M.F. Chen: Emergent liver transplantation to salvage a hepatic avulsion injury with disrupted suprahepatic vena cava. Arch Surg 128:1075-1077, 1993.

18. C.H. Hsu, C.C. Wang, R.J. Chen, S . C . Chen , L.B. Jeng, M.F. Chen: Emergency orthotopic liver transplantation for unrepairable liver trauma. J Surg Assoc, ROC 26:1827-1833, 1993.

19. L.B. Jeng, H.Y. Chen, S . C . Chen , T.L. Hwang, Y.Y. Jan, C.S. Wang, M.F. Chen: Upper gastrointestinal tract ablation for patients with extensive injury after strong acid ingestion. Arch Surg 129:1086-1091, 1994.

20. M.F. Chen, T.L. Hwang, L.B. Jeng, C.S. Wang, Y.Y. Jan, S . C . Chen : Postoperative recurrence of hepatocellular carcinoma 205 consecutive cases operated in 15 years. Arch Surg 129:738-742, 1994.

21. CC Wang, MF Chen, CS Wang, YY Jan, LB Jeng, TL Hwang, SC Chen, et al: Gastric leiomyosarcoma: prognostic factors of recurrence and metastasis. J Surg Assoc, ROC 27: 2565-2569, 1994.

22. HM Chen, YY Jan, CS Wang, LB Jeng, TL Hwang, SC Chen, MF Chen: Surgical management of acute occlusion of SMA.

Chen SC-15

J Surg Assoc, ROC 27:2359-2365, 1994.

23. WC Lee, RJ Chen, JF Fang, CC Wang, HY Chen, SC Chen, TL Hwang, LB Jeng, YY Jan, CS Wang, MF Chen, CC Lou, KL Wang, and JN Lin: Rupture of the diaphragm after blunt trauma. Eur J Surg 160:479-483, 1994.

24. YY Jan, SC Chen, TL Hwang, LB Jeng, CS Wang, MF Chen: Clinical analysis of postoperative mortality and morbidity of pancreatic adenocarcinoma. J Surg Assoc, ROC 27: 2728-2737, 1994.

25. LB Jeng, WC Lee, CC Wang, KL Wang, SC Chen, MF Chen, et al: Cytomegalovirus disease in liver transplant recipients. Transplantion Proceedings 26: 2227-2228, 1994.

26. LB Jeng, YC Ho, WC Lee, CC Wang, KL Wang, SC Chen, et al: Clinical and pathologic features of hepatitis b virus reinfection after liver transplantation. Transplantation Proceedings 26:2263-2264, 1994.

27. LB Jeng, MH Cheng, WC Lee, CC Wang, KL Wang, SC Chen, MF Chen, RN Chien, CT Chiu, DY Lin, et al: Extracorporeal membrane oxygenation therapy for adult respiratory distress syndrome developing post liver transplantation. Transplantation Proccedings 26:2237-2238, 1994.

28. LB Jeng, WC Lee, DS Yeh, CC Wang, KL Wang, SC Chen, MF Chen, RN Chien, CT Chiu, DY Lin, YF Liaw, PP-C Tan, and CH Chang: Immunoprophylaxis for hepatitis b virus reinfection after liver transplantation. Transplantation Proceedings 26:2243-2244, 1994.

29. YY Jan, MF Chen, LB Jeng, SC Chen: Delayed presentation of bile duct injuries after laparoscopic cholecystectomy. J Hep Bil Pancr Surg 2:210-215, 1994.

30. BC Lin, YY Chen, JF Fang, TL Chen, HY Chen, SC Chen, TL Hwang, LB Jeng, CS Wang, MF Chen:Carcinoma of gallbladder: a review of 62 surgical patients.J Surg Assoc 27:2700-2708. 1994.

31. MF Chen, YY Jan, LB Jeng, TL Hwang, CS Wang, SC Chen:Obstructive jaundice secondary to ruptured hepatocellular carcinoma into common bile duct: surgical experience of 20 cases.Cancer 73:1335-1340, 1994.

32. LB Jeng, SC Chen, TL Hwang, YY Jan, MF Chen:Resectional therapy for a giant cavernous hemangioma of the liver.Cheng Gung Med J 17:325-332, 1994.

Chen SC-16

33. TL Hwang, CT Chiu, HM Chen, SC Chen, LB Jeng, YY Jan, CS Wang, MF Chen:Surgical results for severe acute pancreatitis - comparison of the different surgical procedures. Hepato-Gastroenterology 42:1026-1029, 1995.

34. HM Chen, YY Jan, TL Hwang, SC Chen, MF Chen: Surgical experience with ten mesenteric venous thrombosis patients. J Surg Assoc, ROC 28:14-20, 1995.

35. JD Lin, CC Huang, HF Weng, SC Chen, LB Jeng:Comparison of membrane proteins from benign and malignant human thyroid tissues by two-dimensional polyacrylamide gel electrophoresis. J Chromatography B 667:153-160, 1995.

36. TL Hwang, CT Chiu, HM Chen, SC Chen, LB Jeng, YY Jan, CS Wang, MF, Chen:

Surgical results for severe acute pancreatitis - comparison of the different surgical procedured.Hepato-Gastroenterology 42:1023-1025, 1995.

37. YY Jan, MF Chen, CS Wang, LB Jeng, TL Hwang, SC Chen:Surgical treatment of hepatolithiasis: long term results. Surgery 120:509-514, 1996.

38. CS Wang, TC Chao, S Hsueh, LB Jeng, YY Jan, SC Chen, TL Hwang, MF Chen: Proximal third gastric adenocarcinoma: results of total gastrectomy by general surgeons and analysis of prognostic factors. J Surg Assoc, ROC 29:382-390, 1996.

39. YY Jan, MF Chen, CS Wang, LB Jeng, TL Hwang, SC Chen:Surgical treatment of pancreatic adenocarcinoma: Taiwan experience.Int Surg 81:52-56, 1996.

40. HM Chen, YY Jan, MF Chen, CS Wang, LB Jeng, TL Hwang, SC Chen, TC Chao:Surgical treatment of choledochal cyst in an adults: results and long-term follow-up.Hepato-Gastroenterology 43(12):1492-1499, 1996.

41. DJ Lin, HS Hwang, SC Chen, TC Chao: Factors that predict metastasis of papillary and follicular thyroid cancers in

Taiwan.Otolaryngology 116:475-482, 1997.

42. MF Chen, CS Wang, YY Jan, LB Jeng, TL Hwang, SC Chen, TC Chao, HM Chen, CC Wang, WC Lee, TS Yeh and YF Lo:

Chen SC-17

Results of pancreatico-duodenectomy for periampullary carcinoma and analysis of prognostic factors for survival. F. Hanyu, K. Takasaki eds “Pancreatoduodenectomy” Springer-Verlag Tokyo. 425-432, 1997.

43. MF Chen, YY Jan, CS Wang, TL Hwang, LB Jeng, SC Chen, TC Chao:The role of hepatic resection in surgery for bilateral intrahepatic stones. Br J Surg 84:1229-1232, 1997.

44. TS Yeh, YY Jan, LB Jeng, TL Hwang, CS Wang, TC Chao, SC Chen, MF Chen: Pancreaticojejunal anastomotic leak following pancreaticoduodenectomy. Multi-variates analysis of perioperative risk factors. J Surg Research 67:119-125, 1997.

45. CS Hwang, S Hsueh, TC Chao, LB Jeng, YY Jan, SC Chen, TL Hwang, PC Chen, MF Chen:Prognostic study of gastric cancer without serosal invasion: reevaluation of the definition of early gastric cancer.J Am College Surgeons 185(5):476-480, 1997.

46. MY Ku, CH Lai, WM Leung, SC Chen:

Sustained complete remission after incomplete chemoradiation complicated with pelvic cellulitis in a patient with recurrent cervical carcinoma: a case report.Chang Gung Med J 20:214-218, 1997.

47. Wen-sheng Huang, Shin-cheh Chen (correspond author). Falsely upstaged breast cancer by 18F-2-deoxy-D-glucose positive emission tomography in a patient with concomitant pulmonary tuberculosis. Annals of Nuclear medicine and sciences 2006.

PAPER PRESENTED: 1. High Pathologic Complete Response in HER 2-positive Locally Advanced Breast

Cancer after Primary Systemic Chemotherapy with Weekly Docetaxel and Epirubicin, BCRT 2007

2. Survival Benefit of Neck Dissection for Breast Cancer Patients with Supraclavicular Lymph Node metastasis ,ASCO 2010