cutting edge of research and science annual report on ... 2013... · annual report on technology...
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T H E U N I V ERS I T Y OF TOL EDO A N N U A L R E P O RT O N T E C H N O LO G Y T R A N S F E R
2013F I SC A L Y E A R
Technology TransferThe process of transferring creations, discoveries and innovations resulting from university research to the commercial sector.
Cutting Edge of Research and Science
The University of Toledo (UT) technology transfer team provides professional services to faculty, staff and students as they pursue development of commercializable innovations that create new jobs and economic growth for the local community and the world beyond.
The team’s primary duty is to smoothly facilitate the transfer of UT-developed creations, discoveries and innovations to the marketplace. They do this by guiding inventors through the intricate process of protecting and licensing their intellectual property, identifying and helping to secure funding including grants and sponsored research opportunities for further development, and working with inventors to help their platform technologies move toward becoming successful University spin-off businesses.
Other functions of the technology transfer team include:
• Assisting inventors with completing and submitting invention disclosure forms
• Analyzing commercial potential of creations, discoveries and innovations
• Obtaining protection for intellectual property and marketing technologies to potential licensees
• Preparing and executing agreements including confidentiality, material transfer, industry sponsored
research, inter-institutional, memoranda of understanding, and licenses
• Developing and maintaining relationships with industry to receive feedback quickly
on new technologies and/or execute agreements
Translating UT research into commercial success
The numbers tell the story
21 Medicine & Life Sciences
39 Engineering
8 Pharmacy
14 NSM
2 CCI
1 IT
2 EDU
2 UTMC 1 LLSS
INVENTION DISCLOSURES BY COLLEGE FY2013 TECHNOLOGY TRANSFER METRICS
Agreements Processed
Licenses and Options
Licensing Revenue
Invention Disclosures
It is commonly known that state and national funding opportunities are available to academic researchers for basic research. What is not as well known is that the latest trend from some of these funding sources is a requirement that the technology possesses strong intellectual property that can be validated as commercially valuable with the potential of adding to economic growth in the form of new technology-based products that will form the basis of start-up companies and new jobs.
Ohio Opportunities: The Third Frontier Technology Validation and Start-Up Fund (TVSF) is one way in which UT’s Technology Transfer Office collaborates with faculty inventors. The fund is offered for two different phases of development and is available on a periodic basis to Ohio institutions of higher education and start-up companies that have licensed intellectual property (IP) from those institutions. Phase 1 provides up to $50,000 from the fund plus 1:1 matching funds from the institution to help researchers generate proof needed to move the technology to the point that it is ready to be licensed by an Ohio start-up company or deemed unfeasible for commercialization. The funding pays for validation activities such as prototyping, demonstrations and assessment of critical failure points in subsequent development, scale-up, and commercialization. Phase 2 provides up to $100,000 for start-up companies that have licensed IP developed at Ohio research institutions during the critical early life of the company to help accelerate the time to market.
Since its inception in January 2012, more than $800,000 has been awarded to
UT inventors and start-ups from TVSF and matching funds to support development of commercializable products and processes. In fact, UT has claimed nine TVSF grants — second only to The Ohio State University
with a total of 12. The other 26 awards granted thus far were divided among 13
other Ohio universities.
Looking for research funding?
Other Funding: National Science Foundation (NSF) I-Corps grants are another good source of funding. The fund was created to develop and nurture a national innovation ecosystem by helping discoveries from fundamental research become new technologies that benefit society. Since that program’s inception in July 2011, UT faculty members Drs. Vijay Devabhaktuni, Mohammad Elahinia, Champa Jayasuriya, Rashmi Jha and Ashok Kumar have received five of 11 such grants awarded to Ohio inventors.
Inventors wishing to apply for TVSF or NSF I-Corps funding are invited to contact Anne Izzi in the Technology Transfer Office at 419.530.6226 or [email protected] to learn how we may be able to help secure funding.
BIOENGINEERING
PLASMONIC-BASED BIOMARKER SENSING TECHNOLOGYThis technology, developed by Dr. Brent Cameron and Dr. Dong-Shik Kim, is a two-part process that allows for the rapid prototyping of surface plasmon resonance (SPR) sensors that are customizable toward almost any available biomarker. The first product planned for commercialization is expected to be a portable handheld sensor, capable of providing low-cost ultra-accurate glycemic compliance assessment for the diabetes market. In addition, the technology will allow multiple biomarkers to be analyzed in a single bio-sample through an image-based measurement. In this case, by using a single patient sample (i.e. saliva, serum, etc.), a detailed analysis and screening for numerous biomarkers occurs simultaneously. Based upon existing testing, it is anticipated that this technology will provide comparable performance to established clinical/lab-based technology, but in a handheld package and will be available at a fraction of the cost.
MECHANICAL, INDUSTRIAL AND
MANUFACTURING ENGINEERING (MIME)INJECTABLE BONE CEMENT Dr. Sarit Bhaduri and his team have developed an injectable calcium phosphate-based (Ca-P) bone cement which can be easily manipulated and avoids problems inherent in currently available products. This new compound is a robust and unique composition and requires only one solid ingredient as compared to two in other products. The unique formulation of the cement allows it to flow
smoothly and homogeneously and results in uniform resorption and increased strength with improved injectability and cohesiveness. In addition, the product provides optimum viscosity and smoother flow and solves the difficulties of measuring and mixing ingredients as required with other products.
BIOENGINEERING
FACET FIXATION SCREWDr. Vijay Goel and Dr. Anand Agarwal have developed a minimally-invasive spinal fixation system, allowing for a small incision and a minimal morbidity approach to provide a solution for spinal stenosis. The system possesses a major competitive edge because it delivers bone through the use of bridging technology without an additional procedure and without compromising the stability of the fixation. The technology harnesses the bone without use of a rod, and allows more flexible motion than a rigid screw/rod construct with no loosening of the facet screw. In addition, a solid locking implant and fusion prevent further slippage and facet joint pain. The patient experiences a shorter, minimally-invasive procedure with faster recovery time and no clinical compromise. This translates to shorter hospital stays, improved clinical outcome and cost effectiveness.
CONGRATULATIONS!UT’s successful Ohio Third Frontier grant recipients
MECHANICAL, INDUSTRIAL AND MANUFACTURING
ENGINEERING (MIME)/COLLEGE OF MEDICINE
AND LIFE SCIENCES
PERCUTANEOUS MECHANICAL THROMBECTOMY DEVICEA team led by Dr. Mohammad Elahinia and Dr. Christopher Cooper has developed a minimally-invasive cardiovascular device that removes blood clots and reduces the risk of secondary clot formation along with the associated complications and fatalities. The prototype device uses a pair of superelastic nitinol elements to aid in the collection of a thrombus and minimize distal embolization. One of the key advantages of this device over others is the use of a guidance funnel which helps to evacuate pieces of thrombus without shearing the clot into smaller pieces. Based upon initial in vitro testing, the prototype device shows superior performance to existing clot control devices in reducing the number of small blood clots that are produced during the removal of the main clot. The technology also has applications to a wide range of other nitinol-based cardiovascular devices.
BIOENGINEERING/CHEMICAL ENGINEERING
NANO-BIOSENSOR FOR INFECTION IN TISSUEThis novel biosensor developed by Dr. Anand Agarwal and Dr. Dong-Shik Kim is extremely adaptable and may be designed to detect any specific bacteria that may cause infection in bone structure. Pathogens to be detected include but are not limited to methicillin-resistant Staphyloccus aureus (MRSA) and Escherichia coli (E. coli) which are common sources of post-surgical infection. In
fact, the biosensor can be designed to detect any gram-positive or gram-negative bacteria and rapidly differentiate between the two, providing immediate results to surgeons during surgery, thus greatly reducing or eliminating complications of infection during the post-surgery period.
CHEMICAL ENGINEERING/CIVIL ENGINEERING
NON-TOXIC ANTIBACTERIAL SURFACTANT/MICROGEL FORMULATIONSDr. Yakov Lapitsky and Dr. Youngwoo Seo have developed novel formulations of microgels that are instrumental in preparing antibacterial mixtures for use in cleaning and personal care products. These microgel dispersions mixed with non-toxic materials may be substituted for commonly used toxic antibacterial agents including triclosan or bleach. These microgels exhibit high antimicrobial activity even at very low concentrations, allowing for rapid killing of large numbers of microbes upon contact without damaging the surface. In addition, these formulations dissolve easily at neutral and alkaline pH levels making the biopolymer even more versatile.
UT ENGINEERING CENTER FOR ORTHOPAEDIC RESEARCH
NEXT GENERATION SPINAL IMPLANTSAssisted by the technology transfer team, Drs. Vijay Goel, Sarit Bhaduri and Anand Agarwal with UT’s Engineering Center for Orthopaedic Research Excellence (E-CORE) recently secured a $2.4 million Innovation Platform Program grant to develop several next generation spinal implants and a therapeutic device from concept to market entry.
Experience + Creativity = Lab-to-Launch The University of Toledo’s Lab-to-Launch program encourages and enables faculty start-up businesses
that can contribute to local and regional economic development. The progressive program is tightly
coordinated and orchestrated to move the highest potential business opportunities from the laboratory
bench to commercial launch as quickly and efficiently as possible.
Our team works closely with faculty inventors to identify potentially valuable commercial opportunities
and connects them with regional economic development organizations, including Innovation
Enterprises (IE) at The University of Toledo, Rocket Ventures (RV) and the Regional Growth Partnership.
These organizations review the technology and business plan and provide services such as
management consulting as well as funding for proof-of-concept and further development to new
start-up companies. In addition, if the business opportunity qualifies, IE and RV can provide additional
funding up to a combined total of $1.25 million.
LAUNCH
NEW IN 2013
Analytic Diabetic Systems, LLC — Brent CameronAnalytic Diabetic Systems is a wholly owned subsidiary of Dayton, Ohio’s Aptima Inc., focused on deploying medical analytics specifically for predicting glucose in both inpatient and outpatient settings.
Butterfly Spine, LLC — Vijay Goel and Anand AgarwalButterfly Spine is dedicated to the discovery, development and commercialization of spinal products that are necessary to fuse a degenerated segment. Its current project is a novel interspinous dynamic fusion device in collaboration with Paradigm Spine.
EndoSphere Spine, LLC — Vijay Goel and Anand AgarwalEndoSphere Spine is a biotechnology company dedicated to the discovery, development and commercialization of a minimally-invasive endoscopic fusion cage that will be used to restore spinal alignment and fusion of a degenerated segment with minor soft tissue trauma.
2012
Imhoteq Biotechnology, LLC — Khew-Voon Chin Imhoteq Biotechnology is dedicated to developing and commercializing a cutting-edge portable biosensor system for testing halal/kosher foods to ensure authenticity and integrity for consumers in the global community of Jewish and Muslim populations.
Digital Therapeutics, LLC — Bashar M. KahalehDigital Therapeutics focuses on developing treatments for orphan diseases with high unmet medical need, focusing particularly on inflammation.
2011 AccuGenomics, LLC — James C. WilleyAccuGenomics provides comprehensive and accurate gene expression tests to diagnose, monitor and direct cancer treatment, and ensure confidence in clinical decisions.
Excellent Energy Solutions (ExEnSo) — Peter Kascak, Ralph Jansen and Timothy DeverExEnSo is developing an innovative flywheel energy storage system that may be used for distributed or centralized energy management. This proprietary system will be combined with enabling technological advances under joint development by ExEnSo, NASA and UT.
2010
Gamma Spine, Inc. — Vijay GoelThrough mathematical testing, Gamma Spine has developed a posterior lumbar disk replacement with a novel design. Once inserted during surgery, the device can be contracted and expanded, allowing surgery to be completed with less risk for spinal nerve root damage.
2009
Acense, LLC — Abdul-Majeed Azad Acense develops and tests sensors focused on early fault warning for oil-immersed electrical equipment.
2008
ADS Biotechnology, Ltd. — Joseph Shapiro, David Dignam and Ragheb Assaly ADS Biotechnology is developing a revolutionary approach for treating threatening clinical conditions. The company’s primary product, pegylated albumin, is a therapeutic colloid-type blood volume expander agent that is superior to human serum albumin.
Lucintech, Inc. — Al Compaan Lucintech is developing CdTe thin-film photovoltaics on polyimide substrates.
2007
SuGanit Systems — Sasidhar Varanasi, Connie Schall, Jared Anderson, Patricia Relue and Glen LipscombSuGanit Systems is involved in R&D of renewable and clean energy with a focus on ethanol production from biomass including algae.
2006
Xunlight Corporation — Xunming DengXunlight develops, markets and manufactures low-cost, thin-film, silicon-based photovoltaic products and manufacturing equipment for high-throughput production of flexible and lightweight photovoltaic modules.
Spinal Designs — Ashok BiyaniSpinal Designs provides products and services to orthopaedic surgeons.
Freedom Meditech — Brent CameronFreedom Meditech is a developmental stage medical device company focused on non-invasive blood glucose testing for diabetics.
2005
The Turning Point, LLC — Vijay Goel, Danny Pincivero, John Jaegly and David Dick The Turning Point produces state-of-the-art golf exercise and therapeutic devices for spine strengthening and rehabilitation.
2002
Mithridion — Wayne Hoss and William S. MesserMithridion is an emerging biotech company focused on the discovery and commercialization of treatments for neurological and psychiatric diseases.
2001
Schneider and Morse Group — Roy Schneider and Dennis MorseThe Schneider and Morse Group develops computer-based educational tools for animal anatomy and dissection.
Start-ups*
* Start-ups were established to commercialize technology developed by named faculty member(s).
FY2013 Invention DisclosuresCENTER FOR CREATIVE INSTRUCTION Daniel Brainard, Brock Clagg, Eric Eitniear, Tonya Floyd-Bradstock, Roy Schneider, Sherry Andrews, Jamie Carothers and Lisa Procyk WebSim/Prep/Sim 101 Patient assessment tools for cardiac
and respiratoryDaniel Brainard, Brock Clagg, Tonya Floyd-Bradstock, Roy Schneider, Susan Shible, Sherry Andrews, Jamie Carothers, Lisa Procyk and Brian Szabo Anatomy and Physiology Revealed: Cat
INFORMATION OPERATIONS TECHNOLOGY MANAGEMENTJeffrey Coyne UTAD printer automation
JUDITH HERB COLLEGE OF EDUCATION, HEALTH SCIENCE AND HUMAN SERVICEEarly Childhood, Physical and Special EducationCharlene Czerniak, Joan Kaderavek, Geoff Milewski, Tamala North and Regina Rotshtein Teacher assessment tool: The Systematic Coding of Inquiry Instruction
in Early learning Classrooms (SCIIENCE)
Rehabilitation Sciences Martin Rice RAPB-Random assignment with permutated blocks
COLLEGE OF ENGINEERINGBioengineeringNathaniel Westphal, Jennifer Guilford, Matthew Stasa and Marcus Sinewe Automated body fluid measurement systemEmily Breitner, Kristopher Rager, Matthew Rottinger and Frank Wagoner, Jr. Instachill instant cold packAakash Agarwal, Anand Agarwal, David Dick and Vijay Goel Interbody fusion device for minimally invasive implantationHang Shao, Agasteswar Vadiamani, and Patricia Relue Enzymatic digestion of microalgal biomass for lipid, sugar
and protein recoveryAnand Agarwal, David Dick and Vijay Goel Revised bioactive facet and pars fixation deviceAnand Agarwal and Vijay Goel Biosensor — Device to detect infection in real time
Novel shape memory polymer intervertebral cage design
Injectable biodegradable bone matrix for multiple myeloma lesion augmentation and osteoporosisAnand Agarwal, Vijay Goel, John D’Onofrio, Nathaniel Dubois, Jared Pack and David Taylor Stabilized spinal hook implantAnand Agarwal, Vijay Goel and Eda Yildirim Injectable nanofibrous stem cell-contained bone substitute for
fracture augmentationAnand Agarwal, Vijay Goel and Huan Zhou Production of bone cement and bioglass from egg shellsHuan Zhou Rare-earth containing biodegradable nanocrystalline magnesium alloys
for implant applications
Brent Cameron and Brandon Clarke Single crystal integrated magneto-optic modulator and compensatorHoangha Dao, Nicholas Liber and Scott Molitor Teacher assessment tool: The Systematic Coding of Inquiry Instruction
in Early learning Classrooms (SCIIENCE)Nathan Reaver Process and design for uptake of nutrients in agricultural drainage water
by native plant species used to produce biofuel and agricultural fertilizerVijay Goel Head restraint for automobile seatsVijay Goel and David Dick Core Axis
Chemical and Environmental EngineeringHamid Feyzizamagh, Dong-Shik Kim and Do-Young Yoon Biosensor — Device to detect infection in real timeDong-Shik Kim Injectable biodegradable bone matrix for multiple myeloma lesion
augmentation and osteoporosis Novel neurotrophic agents, LA-GAGR, and mini-GAGR Flow-induced electromagnetic anti-fouling technology
(FI-EMAF Technology)Sasidhar Varanasi and Sridhar Viamajala Enzymatic digestion of microalgal biomass for lipid, sugar
and protein recovery
Civil EngineeringYoungwoo Seo Flow-induced electromagnetic anti-fouling technology
(FI-EMAF Technology)Ryan McKibben Sustainable regional waste management facility Chirjiv Anand, Defne Apul, Jay Devkota and Hannah Schlachter Economic and environmental analysis of sanitation technologies
(EEAST) beta version
Economic and environmental analysis of sanitation technologies (EEAST) manual
Defne Apul and Jay Devkota Tools for evaluation of rainwater harvesting systems R2P2 report
Economic and environmental analysis of sanitation technologies (EEAST) associated videos
Electrical Engineering and Computer SciencesThomas Stuart High voltage system using PV windows to power fluorescent lighting
Simplified Mppt controller for PV panels
Maximum power point tracker (MPPT) to interface Building Integrated Photovoltaics (Bipv) to DC fluorescent lighting
Andrew Polasko and Michael Lumbrezer E-waste receptacle
Engineering TechnologyTom Burden Aircraft safety matsDavid Lillibridge Water/fire detection and notification systemKurt Schilling, Carolyn Damo, Jennifer Haupricht and Andrew Bruno Nause-a-wayEamon Kelley, Derek Deland and David Lillibridge Toilet overflow shut-off
Mechanical, Industrial and Manufacturing Engineering (MIME)John Setlock Generation of high pressure oxygen via electrochemical pumping in a
multi-stage electrolysis stack Garrett Rayman, John Leis, Alexander Ritzenthaler, Revillo Stevens and David Schroeder Pivot arm for ability to foot/hand pedal on bicycle trailerPaul Lawson Windshield washer fluid alternativeAhalapitiya Jayatissa Bone graft substitute materialSarit Bhaduri Production of bone cement and bioglass from egg shell
Rare-earth containing biodegradable nanocrystalline magnesium alloys for implant applications
Masking the bitter taste of lidocaine LCI injectable formulation for dental procedures
Novel shape memory polymer intervertebral cage design
Injectable biodegradable bone matrix for multiple myeloma lesion augmentation and osteoporosis
Sarit Bhaduri, Raymond Wetzel, Scott Rawlings and Jason Andler Tie CaddyJoseph Pequignot, Benjamin Sekas, Anthony Cherol, Alexander Stogran, Richard Mescher, Justin Yackee, Christopher Harris and Lesley Berhan EcoSmart Bus BenchMatthew Franchetti, Connor Kress, David Levanduski, Alec Broyles, Jacob West and John Hart Ferro Fluid Electromagnet Plastic Particle SeparatorMohammad Elahinia and Milad Hosseinipour Intra-ventricular assistive device for end-stage cardiac patients Liberty Deberg, Mohammad Elahinia, Masood Taheri and Milad Hosseinipour Shape memory alloy ankle foot orthosis for addressing drop footMohammad Elahinia and Mohammadhassan Sofla Optimum prosthetic and orthotic design concept, method and softwareMohammad Elahinia and Phillip White Mitigating concussion: An innovative football helmetMohammed Hefzy, Adam Dellinger, Chao Xue, Benjamin Zellers and Mehdi Pourazady Air ChairPhillip White, Thomas Bruecker, Matthew Curcio, James Forrester, Josh Hewitt, Jeremy Oroguany and Kyle Pitchler Automated beverage bottle opener Yong Gan, Paul Lawson, Andrew Moening, Omar Mohammed and Matthew Haubert Biophoto fuel cell
COLLEGE OF LANGUAGES, LITERATURE AND SOCIAL SCIENCESGeography and PlanningCathy Schaffer Behavior Therapy App
COLLEGE OF MEDICINE AND LIFE SCIENCESBiochemistry and Cancer BiologyCynthia Smas RIFL as a regulator of lipid metabolism in humansIvana de la Serna and Archit Trivedi Method for modulating pigmentation by targeting BET bromodomain proteinsStephan Patrick Inhibitors of ERCC1-XPF
Dentistry Michael Nedley Masking the bitter taste of lidocaine LCI injectable formulation for
dental procedures
MedicineThomas Blomquist, Erin Crawford and James Willey Standardized RNA sequencing (Starseq)
Standardized RNA sequencing (Starseq) IIErin Crawford, James Willey and Jiyoun Yeo Two-color real-time PCR methods that enable quality-controlled molecular
diagnostic test in FFPE samples
NeurosciencesJoshua Park Novel neurotrophic agents, LA-GAGR, midi-GAGR, and mini-GAGR
Operating RoomGregory A. Cook Tie Caddy
Orthopaedic SurgeryAmbalangodage Champa Jayasuriya Bone graft substitute material
PathologyKenneth Hensley Semaphorin-blocking antibodies to treat motor neuron disease Novel neurotrophic agents, LA-GAGR, midi-GAGR and mini-GAGR
Physiology and PharmacologyNader Abraham, Bruce Heck and DongHyun Kim EET (Epoxyeicosatreienoic acid), Antagonist and agonists in the treatment of
osteoarthritis, osteoporosis, metabolic bone disease and fracture management
PPAR & Delta (Peroxisome-Proliferator-activated receptor & delta) antagonist and agonists in the treatment of osteoporosis, osteoarthritis, metabolic bone disease and fracture management
Bruce Heck and DongHyun Kim 20-OH-PGE2 analogues and EET analogues in the treatment of osteoarthritis,
osteoporosis, metabolic bone disease and fracture management
SurgeryAndrea Kalinoski Nanostructured mists for targeting compounds into the lungsReginald Baugh History of present illness trainerThomas Schwann Automated body fluid measurement system
UrologyMichael Rees Kidney paired donation combination assessment rather than immediate
optimization
Process to identify critical costs and strategies to reduce these costs in complex medical conditions for health-care organizations
Reverse-transplant tourism
Combining desensitization and kidney paired donation to achieve kidney transplantation
International kidney paired donation as a means to recruit international patients to America
Bradley Buck and Stephen Selman Syllabus for student on urology rotation
COLLEGE OF NATURAL SCIENCES AND MATHEMATICS
Biological SciencesAnthony Quinn BBR3378 mediated regulation of autoimmune diseaseWilliam Taylor New class of highly selective anticancer agents targeting non-small
cell lung cancer Boren Lin Biosensor — Device to detect infection in real time Injectable biodegradable bone matrix for multiple myeloma lesion
augmentation and osteoporosisLirim Shemshedini A-8r peptide derivatives
ChemistryLorenza Favrot and Donald Ronning Method for inhibiting the enzymatic activity of enzymes encoded by the
fbp genes of actinobacteria Terry Bigioni, Brian Conn and Ahil Desireddy Method to synthesize pure Ag44(Sr)30m4 cluster molecules Pure Ag44(Sr)30m4 cluster moleculesEric Findsen, Dragan Isailovic, Zhen Sun and Raymond West Atmosphere pressure visible-wavelength MALDI-MSDean Giolando Alumina coating on plastic article to impact abrasion resistance
Transparent conducting oxides coatings prepared at high temperaturesDean Giolando and Ahmad Taha Robust tin oxide coated triple junction solar cells
Environmental SciencesDaryl Dwyer and Kristopher Barnswell Process and design for uptake of nutrients in agricultural drainage water
by native plant species used to produce biofuel and agricultural fertilizer
Physics and AstronomyAlvin Compaan, Michael Heben, Rajendra Khanal and Adam Phillips Copper-free back contact for CdTe solar cell devicesRandall Ellingson, Michael Heben and Anthony Vasko Solar window with built-in electrical system
Carbon nanotube/metal grid transparent and conducting layer for photovoltaics and other applications
Alvin Compaan, Hasitha Mahabaduge, Victor Plotnikov and Kristopher Wieland Front interfacial layer to improve Cdte-based cell performance
COLLEGE OF NURSINGCenter for Continuing Nursing EducationDeborah Mattin WebSim/Prep/Sim 101 Patient assessment tools for cardiac and
respiratory
COLLEGE OF PHARMACY AND PHARMACEUTICAL SCIENCES
Medicinal and Biological ChemistrySara Fedorka and Liyanaaratchige Tillekeratne New class of highly selective anticancer agents targeting non-small
cell lung cancer Paul Erhardt Inhibitors of ERCC1-XPF 20-OH-PGE2 analogues and EET analogues in the treatment of
osteoarthritis, osteoporosis, metabolic bone disease and fracture management
Paul Erhardt and Neha Malik Synthesis of 6a-Hydroxypterocarpans via intramolecular benzoin
condensation
PharmacologyFrederick Williams Nanostructured mists for targeting compounds into the lungsMiles Hacker BBR3378 mediated regulation of autoimmune disease Youssef Sari MS-153 as a drug for the treatment of alcohol dependence
Pharmacy PracticeSai Boddu Masking the bitter taste of lidocaine LCI injectable formulation for
dental proceduresXiaodong (Robert) Wang Design, synthesis and studies of small molecules for cystic fibrosisSai Boddu, Jerry Nesamony and Ashish Kaira Nanostructured mists for targeting compounds into the lungs
UTMC
Cardiac RehabilitationDalynn Badenhop, Stephanie Mousoulias and Catherine Roberts The University of Toledo Medical Center Cardiac Rehabilitation Individual
Treatment PlanFamily MedicineRadha Ramana Gokula Effect of chia seeds on hydration; development of a food beverage
GERIALYTE/CHIALYTE
PharmacyValerie Householder, Geoffrey Mospan and Cindy Puffer Rxpectations MTM (Medication Therapy Management)
Patents!The University of Toledo would like to recognize the following inventors’ contributions in promoting the progress of science through designation as an inventor on one or more patent grants. Names in gold are inventors who contributed to patents that were issued in fiscal year 2013. UT has been issued more than 185 U.S. patents since 1972.
Mamoun Alhamadsheh
Richard Andaloro
Donald Angelbeck
Bernard Arulanandam
Ragheb Assaly
Bradley Austermiller
Abdul-Majeed Azad
Kenneth Bachmann
James Baril
Ashok Biyani
Gloria Borgstahl
Michael Brattain
Renee Buchanan
Jeffrey Burnham
James Byers
Brent Cameron
Yang Cao
Keming Chen
Xia Chen
Jiqi Cheng
Garry Cole
Alvin Compaan
Erin Crawford
Anantha Dadi
Julian Davies
Robert Deck
Laurent Deloux
Jeffery DeMuth
Xunming Deng
David Dick
John Dignam
Philip Dunbar
Graham Durant
Sylvain Dutremez
Paul Erhardt
Ervin Faulmann
John Feldmeier
Ronald Fournier
Peter Fraleigh
James Fry
Kuan-Chen Fu
James Gano
Greta Garbo
Dean Giolando
Vijay Goel
Peter Goldblatt
Stephen Goldman
Bing Gong
Anne Graves
Akhlesh Gupta
Jiwan Gupta
George Hageage
James Hampton
Gregory Haselhuhn
Judy Hendricks
Channing Hinman
James Horner
Wayne Hoss
Xuefei Huang
Richard Hudson
Chiung-Yu Hung
James Huttner
Clara Jackson
John Jaegly
Douglas Jambard-Sweet
Jerzy Jankun
Ralph Jansen
Ahalapitiya Jayatissa
Victor Karpov
Stamatios Kartalopoulos
Peter Kascak
Rick Keck
Amin Khan
Roger King
Jon Kirchhoff
Thoe Kirkland III
Rita Klein
Wieslaw Klis
Charles Knight
Steven Kramer
Kenneth Kropp
Frederick Kurtz
Harold Lee
Aklilu Lemma
Marc Levine
Xianbo Liao
Jeffrey Lovelace
Jian-Yu Lu
Rosa Lukaszew
Edward Lumsdaine
Xianda Ma
Parani Madasamy
Konstantin Makhratchev
Maurice Manning
William Messer Jr.
Dennis Metzger
Alan Morgan
Naser Mostaghel
D’Anna Mullins
Durgesh Nadkarni
Ganapathy Naganathan
Terry Ng
Babatunde Ojo
Ishmael Parsai
Danny Pincivero
Henry Povolny
Kent Price
Demetrios Raftopoulos
Walajapet Rajeswaran
Glenn Reimer
William Roll
Yann Roussillon
Sairam Rudrabhatla
Jeffrey Sabin
Murray Saffran
Jeffrey Sarver
Connie Schall
Padmanabhan Sekher
Steven Selman
Kalpathi Seshan
Joseph Shapiro
Diana Shvydka
Henry Simon
Dimitris Skalkos
Ewa Skrzypczak-Jankun
James Slama
Clifford Smith
Edward Snell
Morris Srebnik
Sujatha Srinivasan
Thomas Stuart
Desikan Sundararajan
Verner Swanson
Sridhar Thirupathi
Jiang Tian
Liyanaaratchige Tillekeratne
James Trempe
Stefan Uhlenbrock
Sasidhar Varanasi
Yu Wang
David Weaver
James Willey
Zi-Jian Xie
Liwei Xu
Jianmin Xue
Qicheng Yang
Zhong Ye
Jieh-Juen Yu
Quilin Yu
Bin Zheng
Donald Zrudsky
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