Curriculum Vitae Name: Noriko, OSUMI, DDS, PhD Present position:

Professor, Department of Developmental Neuroscience Chair, Center for Neuroscience Director, United Centers for Advanced Research & Translational Medicine (ART) Tohoku University School of Medicine

Academic and Professional Career

1979-1985 School of Dentistry, Tokyo Medical & Dental University 1985-1989 Graduate School of Dentistry, Tokyo Medical & Dental University 1989-1996 Research Associate, Department of Craniofacial

Morphogenesis & Anomalies, Tokyo Medical & Dental University

1996-1998 Associate Professor, National Institute of Neuroscience, National Center of Neurology & Psychiatry

1998- Present position 2007- Special Advisor for Gender Equality (Tohoku University) 2007-2014 Member of Science Council of Japan (three terms) 2008-2011 Distinguished Professor (Tohoku University) 2010-2011 Visiting Professor, MCB, Harvard University 2011- Director of Core Center for Neuroscience 2012- TWAS Associate Member 2014- Associate Member of Science Council of Japan 2015- Director of United Centers for Advanced Research &

Translational Medicine

Award 1985 Nagao Award from School of Dentistry, Tokyo Medical &

Dental University (for the top student on graduation) 1992 Hatton Travel Award from International Association for Dental

Research for the 70th General Session of the IADR 2006 NISTEP Award from MEXT

Committees (only selected):

Past President, the Molecular Biology Society of Japan Organizing Member, The Japan Neuroscience Society Organizing Member, Japanese Society for Cell Biology Editorial Board, Journal of Anatomy Editorial Board, Genes to Cells Editorial Board, Neuroscience Research Editorial Board, Development Growth & Differentiation Member, Peer Review Committee for Governmental Grants (MEXT) Member, Advisory Committee for Life Science (MEXT) Member, Committee for Ethical Problems in Human ES Cells Member, Committee for Institute for Frontiers Medical Science, Kyoto

University Advisor for WPI-iCeMS at Kyoto University Evaluation Committee Member for WPI-IIIS at Tsukuba University Selection Committee Member for Japan Prize, Kyoto Prize, Keio Prize etc. Biosketch

Prof. Osumi has graduated Tokyo Medical and Dental University, been given PhD thesis from the same university, and now is a professor of Tohoku University School of Medicine since 1998. She was one of the 25 Distinguished Professors in Tohoku University from 2008 to 2011. Her research interest covers broad areas such as pre- and postnatal development of the brain, sensory organs, and craniofacial region, and behavior of animals as models of psychiatric diseases. More recently, she eagers to understand regulatory mechanisms for transgenerational effects of paternal aging in regard with offspring’s behavior. Manipulating embryos and imaging brain cells are expertise of her lab. She is appointed in various governmental committees such as ethical issues, grant system development, and career paths for young scientists. She was also chosen as a youngest member of Japanese Council Japan in 2005 and served for 9 years. She has become Associate Fellow of TWAS (The World Academy of Science) since 2012. She has translated three books into Japanese: Essential Developmental Biology by Jonathan Slack, The Birth of the Mind by Gary Marcus,

and Why Aren’t More Women in Science? edited by Dr. Stephan Ceci. She was a representative of CREST project (2005-2010) supported by JST and Global COE project (2007-2012) supported by MEXT.

Publication (see Researchgate for full version https://www.researchgate.net/profile/Noriko_Osumi)

Matsuo T*, Osumi-Yamashita N* et al.: A mutation in Pax6-gene in Small eye rat is associated with impaired migration of midbrain crest cells. Nat Genet, 3(4), 299-304, 1993 (*equally contributed) Osumi-Yamashita N et al.: The contribution of both forebrain and midbrain neural crest cells to the mesenchym in the frontonasal mass of mouse embryos. Dev Biol, 164(2), 409-419, 1994 Fujiwara M, Uchida T, Osumi-Yamashita N, Eto K: Uchida rat (rSey): a new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant. Differentiation, 57(1), 31-38, 1994 (cited with figures in Developmental Biology textbook by Scott Guilbert) Akamatsu et al.: Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous system. Proc Natl Acad Sci USA, 96(17), 9885-9890, 1999 Watanabe et al.: Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype. PLoS Biol, 5(11), e297, 2007 Sakurai K and Osumi N: The neurogenesis controling factor, Pax6, inhibits proliferation and promotes maturation in murine astrocytes. J Neurosci, 28(18), 460604612, 2008 Maekawa et al.: A novel missense mutation (Ley46Val) of PAX6 found in an autistic patient. Neurosci Lett, 462(3), 2670271, 2009 Umeda et al.: Evaluation of Pax6 mutant rat as a model for autism. PLoS ONE, 5(12), e15500, 2010 Tsunekawa et al.: Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates. EMBO J, 31(8), 1879-1892, 2012 (chosen as “Have you seen?” article in EMBO J and as “Editor’s Choice” in Science) Nagasaki et al: Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nat Comm, 2015 Aug 21; 6: 8018. doi: 10.1038/ncomms9018,