curriculum vitae prof. manickam … no 6-cv of prof ravi.pdf · a. b.sc biotechnology program ......

CURRICULUM VITAE

PROF. MANICKAM RAVICHANDRAN

Prof. M. Ravichandran, Curriculum vitae 2017

2

Table of contents Page No.

1. Personal Particulars ................................................................................................ 3

2. Academic Qualifications .......................................................................................... 3

3. Work Experience ..................................................................................................... 3

3.1 Professor, Dean And Head Of The Department Of Biotechnology ................... 4 3.1.1 Significant Acheivements ............................................................................... 5

A. B.Sc Biotechnology Program ........................................................................... 5 B. Postgraduate Program .................................................................................... 6 C. Research And Development ............................................................................ 6

3.2. Associate Professor .......................................................................................... 6 3.2.1 Significant Acheivements................................................................................ 6 3.3 Lecturer ............................................................................................................. 7 3.3.1 Significant Acheivements................................................................................ 7 3.4 Postdoctoral Fellow ........................................................................................... 7 3.5 Scientist ............................................................................................................. 7

4. Research Grants ..................................................................................................... 7

5. Awards And Recognistion For Academic And Research Capabilities ................... 10

6. Quality Management Other Qualifications ............................................................. 14

7. Research Publications In Journals ....................................................................... 15

7.1 Research Publications In Book ........................................................................ 22 7.2 Publication In The Web Site ............................................................................ 23

8. Media Reports ....................................................................................................... 23

9. Students Supervision/Examination ........................................................................ 23

9. 1 Post Graduate Students ................................................................................. 23 9.2. Postgraduate Degree Thesis/Dissertation Examination ................................. 27

10. Invited Lectures ................................................................................................... 28

10.1 Plenary Lectures ............................................................................................... 28

10.2 International Lecture ......................................................................................... 29

11. Patent Application ............................................................................................... 31

12. Consultancy ........................................................................................................ 32

13. Major Commercial Achievements ........................................................................ 32

14. Professional Services .......................................................................................... 32

14.1 Expert Panel Member And Examiner ........................................................... 32 16. Committees/Members .................................................................................... 33

17 . Professional Membership ................................................................................... 34

Prof. M. Ravichandran, Curriculum vitae 2017 3

MANICKAM RAVICHANDRAN

Chief Executive & Vice Chancellor AIMST University, Semeling 08100 Bedong, Kedah MALAYSIA

1. PERSONAL PARTICULARS

Date of Birth 20 August 1967 IC Number 670820-75-5015 Citizenship Indian, Malaysian PR

Marital status Married with two children

2. ACADEMIC QUALIFICATIONS

1992-1997 Ph.D in Biotechnology: Cytokine gene expression studies in Human Lymphatic Filariasis, Anna University, Madras,TN, India. 1988-1991 M.Sc.-Medical Microbiology, Christian Medical College, Vellore, TN, India. 1985-1988 B.Sc. Botany with Zoology and Chemistry as ancillary subjects, Madurai Kamaraj University, Madurai, TN, India. OTHER QUALIFICATIONS

1. Case Western Reserve University.OH, USA “Inspiring Leadership through Emotional Intelligence” A Coursera -MOOC online course, 29 January 2014.

2. Birmingham University, UK. “Good Brain Bad Brain: Parkinson‟s Disease”. A Futurelearn -MOOC online course, 19 March 2014.

3. ISO 9001:2000, Certified Lead Auditor, 30 March 2005.

4. GCP - Good Clinical Practice, October 2003. Clinical Trial Unit, Universiti Sains Malaysia.

3. WORK EXPERIENCE

Acting Chief Executive & Acting Vice Chancellor AIMST University, Semeling 08100 Bedong, Kedah, MALAYSIA 17 July 2014 to 30 September 2014 Chief Executive & Vice Chancellor AIMST University, Semeling 08100 Bedong, Kedah, MALAYSIA 1 October 2014 to Present

Email: [email protected] [email protected]

Office:Tel: +604 429 8103 Residence: Tel +604 429 8004

FAX: +604 429 8109 HP: +6 0129595269


3.0 SIGNIFICANT ACHEIVEMENTS AS VICE CHANCELLOR

UNIVERSITY OPERATIONS i. Paper work done to renew University License from Ministry of Higer

Education, Malaysia - obtained 11 September 2014

ii. University Constitution and Statues drafted to comply new Ministry of

Higher education, Malaysia requirement - 3 October 2014

iii. University Board of Governors - Established the new structure

recommended by Ministry of Higher education, Malaysia with the following

subcommittees: Budget committee, Audit committee, Tender Board &

Appraisal and Promotion Committee,

iv. Liaised with Ministry of Higher education, Malaysia and admitted 61 additional

medical students transferred from an University.

v. Drafted the University Strategic Plan 2017-2021.

NEW CENTERS, COMMITTEES, UNITS AND POLICIES ESTABLISHED

i. Central Laboratory Management Unit (CLMU) unit

ii. Postgraduate Centre

iii. Loan Counselling Unit

iv. Environmental meeting to monitor the estate, maintenance, university

services and security.

v. Executive Management Committee established to monitor on the

management issues.

vi. New Academic promotion policies for Professor, Associate professor, Senior

Lecturer and Lecturer was established and implemented successfully.

vii. Fee refund policy has been revised

viii. R&D Management office

ix. Research grant funding from government bodies has reached

RM3,498,034.00 in 2016.

x. Did working paper and successfully obtained the approval for the University as

one of the recipient of ScienceFund, InnoFund and Technofund, Ministry of

Science Technology and Innovation (MOSTI), Malaysia.


xi. First time filed two patents in the University on inflatable bed pan and dengue

mosquito monitoring

xii. New course on Bachelor in Dental Technology, Bachelor in Internal Auditing

Launched for the first time in Malaysia

xiii. STAR- Staff performance rating, to monitor the academic staff performance

quarterly was introduced in addition to SATE- Students assessment on

teaching efficiency, Appraisal system and thumbprint monitoring system.

INTERNATIONAL COLLABORATION

i. Collaboration with Kanagawa University has been enhanced with more

students mobility, staff exchange and more disciplines

ii. Queen Mary University London has been reinvigorated and continued.

iii. New international arenas‟ embarked:

a. Otago University, New Zealand

b. Tzu Chi University, Taiwan

c. France:

i. Universite De Nantes

ii. Leonard De Vinci, Pole Universitaire

3.1 PROFESSOR, DEAN AND HEAD OF THE DEPARTMENT OF BIOTECHNOLOGY

Faculty of Applied Sciences, AIMST University, Semeling 08100 Bedong, Kedah, MALAYSIA 17 September 2008 to Present

3.1.1 SIGNIFICANT ACHEIVEMENTS

A. BSc Biotechnology Program

1. BSc (Hons) Biotechnology Program Entry criteria for BSc (Hons) Biotech was revised to enhance the intake of students (15.8.11)

2. BSc (Hons) Biotech curriculum was revised with inputs from stake holders (15.8.11)

3. Obtained “Grade A“ from MQA – Malaysian Qualification Agency Accreditation for BSc (Hons) Biotech program (28.4.11)

4. Introduced OSPE practical examination

5. Biotechnology Entrepreneurship Special Training (BeST) Programme by Malaysian Biotechnology Corporation has been included in BSc (Hons) Biotechnology Program (June 2012).

6. Campus interview established for. B.Sc (Hons) Biotechnology graduates

7. Achieved a placement rate of 99% for B.Sc (Hons) Biotechnology graduates.


8. Involved in developing innovative programs such as BSc (Hons) Bioinformatics, BSc (Hons) Biotechnology Major is Medical Biotechnology & Agriculture and Aquaculture.

B. POSTGRADUATE PROGRAM

1. Full accreditation has been obtained from MQA – Malaysian Qualification Agency for

MSc Biotechnology Program on 15 July 10 - A4623.

2. MSc Biotechnology student‟s intake number increased by 30.

3. Obtained MQA – Malaysian Qualification Agency accreditation for PhD Biotechnology

program

4. Introduced MBA Biotechnology Management course.

5. Member of the postgraduate committee.

C. RESEARCH AND DEVELOPMENT

1. Established AIMST Human and Animal Ethics committee

2. Established documents and SOPs to receive WHO Strategic Initiative for Developing

Capacity in Ethical Review (SIDCER) recognition for the ethics committee.

3. Took effort to attract RM1.5 million worth of research grant at AIMST University.

4. Established AIMST University Research Review Board and currently the Chairman of

this committee.

5. Established Advanced Molecular Biology Laboratory

6. Registered AIMST University for Welcome Trust and NIH research Grant schemes.

7. Chairman of R&D management office at AIMST University

8. 59 publications in international journals (Cumulative impact factor 119.99), supervised

36 postgraduate students, filed 8 patents and commercialized 3 products on

diagnostics.

3.2. ASSOCIATE PROFESSOR

Department of Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia. October 2004 to 9 September 2008 3.2.1 SIGNIFICANT ACHEIVEMENTS

1. Block Coordinator – Communicable diseases block, MD program, School of Medical Sciences, Universiti Sains Malaysia - 2002 to 2005

2. Course Coordinator - Molecular Biology Techniques BSc, Biomedicine, School of Health Sciences, Universiti Sains Malaysia – 2002 – 2005


3. Course Coordinator - Molecular Biology, DTMP Year 3, Semester 2, 1999-2002

4. Teaching, Microbiology, Parasitology and Molecular biology to Diploma in Medical Laboratory Technology (DTMP), BSc, MD, MMed and MPath students since 1999

5. Established Problem based learning (PBL), Fixed Learning Modules (FLM), School of Medical Sciences, Universiti Sains Malaysia since 1999

6. Cloning simulation project - A virtual cloning project implemented in Molecular Biology Techniques course in BSc, Biomedicine, School of Health Sciences, Universiti Sains Malaysia, since 2000.

7. Teaching websites created 1. Molecular Biology Techniques

a. http://www.ppsk.usm.my/lecturers/mravi/GTB204_2002_Index.htm

2. Communicable diseases

a. http://elearn.kk.usmnet/comdisblock/main.htm

3.3 Lecturer

Department of Microbiology and Parasitology, School of Medical Sciences, Universiti Sains

Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.

March 1999 to September 2004.

3.3.1 SIGNIFICANT ACHEIVEMENTS

1. Founding member of Institute for Research in Molecular Medicine, Universiti Sains

Malaysia (http://www.informm.usm.my). It has been awarded Centre of Excellance Award

(Hi CoE) by Ministry of Higher Education, Malaysia.

2. Established Molecular Diagnostic Laboratory at Department of Medical Microbiology and

Parasitology, USM.

3.4 Postdoctoral fellow

“T-cell epitopes of Plasmodium falciparum”, Department of Microbiology and Parasitology,

Universiti Sains Malaysia. October 1997 to February 1999.

3.5 Scientist

Employed as a Scientist in Govt. of India project on "Molecular Forensics: DNA finger printing techniques ". Anna University, India, September 1996 - September 1997 4. RESEARCH GRANTS

No Funding

body Title Role Duration

Value (RM)

1. FRGS Neural stem cell gene therapy for Cell Signaling

in Parkinsons model in mice Investigator 2014-2016 127,000.00

2. FRGS Discovering and Understanding the Mechanism

of Phage Lysins as Enzybiotics: A novel Co-

Investigator 2013-2015 150,000.00

http://www.ppsk.usm.my/lecturers/mravi/GTB204_2002_Index.htm

http://elearn.kk.usmnet/comdisblock/main.htm

http://www.informm.usm.my/


No Funding


Value (RM)

functional metagenomic approach

3. Potential project, USM

Genetic polymorphism of drugs, in vitro metabolisms of MDMA, artesunate &

amodiaquine and interindividual variability to their responses.

Co-Investigator

2007-2009 270, 375.00

4. `

Golden goose project, USM

Molecular approaches towards preventive, investigative and therapeutic diagnostics for

environmentally – induced diseases Project:1 Molecular and Immunological profiling of typhoid carriers and Salmolella typh: Towards

development of preventive and investigative diagnostics

Co-Investigator

2007-2010

333,333.34

5.


Molecular approaches towards preventive, investigative and therapeutic diagnostics for

environmentally – induced diseases Project 2: Molecular profiling of Toxoplasma

gondii : Towards recombinant antigen and DNA based diagnostics for Toxoplasmosis

Co-Investigator

2007-2010 333,333.33

6. Potential project, USM

Multifaceted Approach of Hospital Associated Infections Control Programme (MAHAICP):

Towards Zero Tolerance HAI

Co-Investigator

2007-2010 225,785.00

7.


Development of gold nanoparticle and glass membrane based universal lateral flow

technology for detection of DNA

Co-Investigator

2007-2009 248,600.00

8. Science

Fund

Development of a nanoparticle based electrochemical biosensor system for the

detection of vancomycin resistance enterococci (VRE)

Investigator 2007-2009 402,488.00

9. MOSTI Evaluation of bivalent O1 and O139 live

attenuated vaccine for cholera: A Malaysia - Cuba initiative

Investigator 2007-2009 1,039,947.00

10. MOSTI Development of Malaysian -Cuban Diagnostic

for Tropical Diseases: Cholera Investigator 2007-2009 126,335.83

11. Science

Fund Leptin and related risk factors in breast cancer

patients Co-

Investigator 2006-2008 164,495.00

12. Science

Fund

Mutation of the virulence and ompA genes of Shigella flexneri: Towards development of an

oral live attenuated Shigella vaccine

Co-Investigator

2006-2008 151,000.00

13. Science

Fund

Experimental RNomics based systemic search for small-non-coding RNA riboswitches in Vibrio cholerae towards discovering novel drug target,

vaccine candidate and diagnostic markers

Co-Investigator

2006-2008 508,660.00

14.

USM short term grant

Endoscopic Findings And Evaluation Of Molecular Method In Detecting Fungal Etiology

In Chronic Rhinosinusitis

Investigator 2006-2008 17610.00

15.


Comparison of Microscopy, PCR and Rapid Immunoassay Test in detection of

Cryptosporidium parvum in Fecal Specimens of HIV infected patients

Co-Investigator

2005-2006 18,990.00

16. USM short

Comparison of Microscopy and PCR in the detection of Pneumocystis carinii in HIV infected

Investigator 2005-2006 11,600.00


No Funding


Value (RM)

term grant

patients admitted at General Hospital Kota Bharu

17. SAGA Does Vibrio cholerae invade gut mucosa?

Exploring the genes involved in enteropathogenesis

Co-Investigator

2005-2006 483,000.00

18. SAGA

Identification and characterization of novel small non-messenger RNAs in Plasmodium

falciparum towards their role in the mechanism of disease in malaria.

Co-Investigator

2005-2006 507,918.96

19.


Effect of omeprazole and chloroquine combination on chloroquine resistant plasmodia

in-vitro and in-vivo

Co-Investigator

2004-2005 9,000.00

20. IRPA*

Topdown RM8

Antimicrobial resistance in Malaysia: A PCR based rapid test for the early detection of

antibiotic-resistance in Enterococcus spp. from clinical samples

Investigator 2003-2006 397,710.00

21. IRPA

long term

Effect of P-Glycoprotein Inhibitors on Chloroquine/Mefloquine resistant Malaria model system in vitro and in vivo: Towards identifying

chemosensitizers for Malaria

Co-Investigator

2003-2006 172,000.00

22.

USM*** short term grant

Pilot study to determinate the prevalence of Herpes simplex infection in cases of viral

conjunctivitis in HUSM using polymerase chain reaction

Co-Investigator

2003-2004 19,750.00

23. NBD** TOP

DOWN

Development Of Diagnostic Tests For Enteric Pathogens: Genomic Approach – Vibrio

cholerae Investigator 2002-2007 194,814.00

24. IRPA* TOP

DOWN

Incorporation of Mutation In Virulence and recA Genes of Vibrio cholerae (Bengal) Vaccine

Strain (USM-VCB1): Towards The Development of an Oral Live Attenuated Cholera Vaccine

Investigator 2002-2004 395,000.00

25. IRPA*

long term Effect of pesticides on surfactant

system of lung Co-

Investigator 2002-2004 291,000.00

26. IRPA*

long term

The role of nitric oxide on the induction of immune response to Actinobacillus

actinomycetemcomittans in a mouse model

Co-Investigator

2002-2004 209,000.00

27. IRPA*

Topdown

Development and Evaluation of Multiplex-Multicolour Molecular Beacons and DNA dipstick Assay Techniques for Genus and

Species Detection of Mycobacteria

Co-Investigator

2002-2004 345,000.00

28. IRPA*

Topdown RM8

Development of a novel immunochromatography test system for the detection of biotype, virulence and antibiotic

resistance genotype of Vibrio cholerae for the early diagnosis of cholera.

Co-Investigator

2002-2004 367,000.00

29. USM*** Short term

Gene frequencies of CSF1PO, TPOX, THO1, FESFEPS, F13A01 and vWA STRs allele in

random Malay population

Co-Investigator

2002-2003 19,000.00

30. FRGS*** Arginase activity in murine macrophages Co- 2002 92,052.00


No Funding


Value (RM)

* stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans in vitro

Investigator

31. USM*** Short term

Effect of rifampicin and chloroquine combination on chloroquine resistant

Plasmodium berghei in mice

Co-Investigator

2001-2002 13,900.00

32.

USM*** short term grant

Evaluation of Multiplex PCR method to detect fungal aetiology in microbial keratitis

Co-Investigator

2001-2002 15,000.00

33. IRPA*

long term grant

Mutation of hemA and M gene of Vibrio cholerae: Towards the development of attenuated V. cholerae vaccine strain"

Investigator 2000-2003 144,000.00

Total 7,257,322.46 *IRPA - Intensification of Research in Priority Areas, Ministry of Science Technology and Innovation (MOSTI) ,Malaysia **NBD – National Biotechnology Directorate, Ministry of Science Technology and Innovation.,Malaysia

*** USM – Universiti Sains Malaysia

****FRGS – Fundamental Research Grant, Ministry of Education, Malaysia *****SAGA- Scientific Advancement Grant Allocation, Science Academy, Malaysia

5. AWARDS AND RECOGNISTION FOR ACADEMIC AND RESEARCH

CAPABILITIES

No Award Title Year

1. Hassanain Al-Talib, Chan Yean Yean, Alyaa Al-Kh ateeb, Habsah Hasan and Manickam Ravichandran. INVENTION, INNOVATION & DESIGN EXPOSITION 2016 (iidex2016) Rapid Detection Of Methicillin And Vancomycin-Resistance Staphylococcus Aureus By A Newly Developed Cold Chain Free PCR Assay. 20-23 September 2016.UiTM, Shah Alam, Malaysia.

2016

2. P. Lalitha, Lee Su Yin, M. Ravichandran & Susan Praveena Thomas. “EZSE-VRE Amp Kit” at MOHE Implementation Plan for Development of Innovative Human Capital at Tertiary Level on 5 March 2013. Ministry of Higher Education, Malaysia.

2013

3. M. Ravichandran, S. Kurunathan, P. Sivachandran & G. Shanta Latchumy , “Aerofaj Aquaclean” at MOHE Implementation Plan for Development of Innovative Human Capital at Tertiary Level on 5 March 2013. Ministry of Higher Education, Malaysia.

2013

4. Bronze Medal: Dr. Lim Boon Huat, Prof. Dr. Pattabhiraman Lalitha, Prof. Dr. Manickam Ravichadran, Dr. Chua Ang Lim, Dr. Chan Yean Yean, Balqis Kamarudin, Elina Husni Tan. Genostick – a rapid universal kit for PCR amplicon detection. International Warsaw Inventions Show (IWIS 2011) , November 03 - 05, 2011 Warsaw, Poland.

2011

5. Gold Medal. Lim Boon Huat, Ravichandran Manickam, Lalitha Pattabhiraman, Chan Yean Yean, Chua Ang Lim, Balqis Kamarudin, Elina Husni Tan. Ez Genostick: A rapid universal kit for the PCR amplicon detection, at International Trade Fair "Ideas Inventions New Products" (IENA), 29 October, 2011, Nuremberg Germany

2011

6. Gold Medal. Lim Boon Huat, Ravichandran Manickam, Lalitha Pattabhiraman, Chan Yean Yean, Chua Ang Lim , Balqis Kamarudin, Elina Husni Tan. EzCholera Genostick: A rapid molecular test kit for the detection of Vibrio

2010


cholerae, at BIO Innovation Awards 2010, 1-3 November 2010, Kuala Lumpur Convention Centre, Kuala Lumpur.

7. Silver Medal, Lim Boon Huat, M. Ravichandran, P. Lalitha, Chua Ang Lim, Chan Yean Yean, Balqis binti Kamarudin, Elina binti Husni Tan. EzGenostick: A rapid universal kit for PCR amplicon detection. 21th International Invention, Innovation and Technology Exhibition (ITEX), 14-16 May 2010, Kuala Lumpur Convention Centre, Kuala Lumpur, Malaysia.

2010

8. Gold Medal, Ravichandran M, Lalitha P, Asma Ismail, Chan Yean Yean, Balqis Kamarudin and Lee Su Yin CHOLERA GENOSENSOR : A DNA-based kit for the rapid detection of Vibrio cholerae. International Trade Fair "Ideas Inventions New Products" (IENA), 5-8 November, 2009, Nuremberg Germany

2009

9. Excellent Service Award, 2007, School of Medical Sciences, Universiti Sains Malaysia

2008

10. Gold Medal, Ravichandran M, Lalitha P, Asma Ismail, Chan Yean Yean, Balqis Kamarudin and Lee Su Yin CHOLERA GENOSENSOR : A DNA-based kit for the rapid detection of Vibrio cholerae. International Exposition of Research and Inventions of Institutions of Higher Learning 2007, Kuala Lumpur Convention Centre, Kuala Lumpur, 10-12 August 2007.

2007

11. Gold Medal Ravichandran. M, Lalitha P, , Chan Yean Yean, Lim Kun Lee,Lee Su Yin, Melissa Chan Li Ann, Mohd Radzi Johari, Habsah bt Hasan, Azian bt Harun, EZVRE Amp- A DNA-based kit for the detection of Enterococcus species and its gentamicin and vancomycin resistant genotypes. 34th International Exhibition of Inventions: New Technologies and Products, Geneva, 5-9 April 2006

2006

12. Silver Medal Asma Ismail Ravichandran. M and Aziah Ismail,. EZTyphi Carrier DNA, 34th International Exhibition of Inventions: New Technologies and Products, Geneva, 5-9 April 2006.

2006

13. Silver Medal Asma Ismail, Mohd Zaki S, Ravichandran. M, Ridhwan A.W and Norzie A.P. EZCampy DNA, 34th International Exhibition of Inventions: New Technologies and Products, Geneva, 5-9 April 2006.

2006

14. Anugerah Inovasi Negara Asma Ismail Ravichandran. M Aziah Ismail and

Foong S. Y. Typhi Rapid product. Showcase Inovasi, Anugerah Inovasi Negara 2006 and Pelancaran Portal Brain Gain, 3-4 Dec 2006, PWTC

2006

15. Gold Medal Lalitha P, Ravichandran. M, Lim Kun Lee, Lee Su Yin, Chan Yean Yean, Melissa Chan Li Ann and Zainul F. Zainuddin. EZAmp Octaplex Cholera: A Thermostabilized and Rapid DNA-based Diagnostic Kit for the Simultaneous Detection of Serogroups, Biotypes, Virulent Genes and Tetracycline Resistant Gene of Vibrio cholerae, 33rd International Exhibition of Inventions: New Technologies and Products, Geneva, 6-10 April 2005

2005

16. Gold Medal Dr. Yap Yoke Yeow, Melissa Chan Li Ann, Lee Su Yin, Shahid Hassan and Ravichandran M. EZEBV Amp: A DNA-based Diagnostic Kit for the Detection of Epstein-Barr Virus in Nasopharyngeal Carcinoma, 33rd International Exhibition of Inventions: New Technologies and Products, Geneva, 6-10 April 2005

2005

17. Gold Medal Ravichandran. M, Lalitha P, , Chan Yean Yean, Lim Kun Lee, Lee Su Yin, Melissa Chan Li Ann, Mohd Radzi Johari, Habsah bt Hasan, Azian bt

2005


Harun, EZVRE Amp- A DNA-based kit for the detection of Enterococcus species and its gentamicin and vancomycin resistant genotypes. 16th International Invention, Innovation, Industrial Design & Technology Exhibition (ITEX), 19-21 May 2005, Putra World Trade Centre (PWTC), Kuala Lumpur, Malaysia.

18. Gold Medal. Asma Ismail Ravichandran. M and Aziah Ismail,. EZTyphi Carrier DNA. 16th International Invention, Innovation, Industrial Design & Technology Exhibition (ITEX), 19-21 May 2005, Putra World Trade Centre (PWTC), Kuala Lumpur, Malaysia.

2005

19. Silver Medal Asma Ismail, Mohd Zaki Salleh, Ravichandran. M, Kirnpal Kaur A/P Banga Singh, Nik Noorul Shakira Mohd Shakrinand EZDysentry DNA. 16th International Invention, Innovation, Industrial Design & Technology Exhibition (ITEX), 19-21 May 2005, Putra World Trade Centre (PWTC), Kuala Lumpur, Malaysia.

2005

20. Young Investigator Award (2nd runner up) Thiruchelvan N, Azni A.M, Zurayani Z, Shafiqul Islam, Haslizai H, Nurainey A, Che Nor Anini, Ravichandran M & Asma I. Characterization and evaluation of an antigenically specific 36kDa surface associated protein of Acinetobacter baumannii; a causative agent of hospital acquired infection, Regional conference on Molecular Medicine, UKM, Medical Molecular Biology Institute (UMBI), Kuala Lumpur, Malaysia 9-11 September 2005.

2005

21. Saintis Cemerlang 2005, Kementerian Pengajian Tinggi 2005

22. Silver Medal Ravichandran, M, Atif Ali, S, Nur Haslindawaty A.R., Kurunathan, S, Lalitha, P, Zainuddin, Z.F VCUSM1/2 vaccine candidates. Genetically attenuated, protective and ecologically safe vaccines for O139 cholera. International Invention, Innovation, Industrial Design & Technology Exhibition (ITEX), 20 -22 May 2004, Kuala Lumpur.

2004

23. Gold Medal P. Lalitha, M. Ravichandran, Lim Kun Lee, Lee Su Yin, Chan Yean Yean, Melissa Chan Li Ann, Zainul F Zainuddin. EZAmp Octaplex Cholera International Invention, Innovation, Industrial Design & Technology Exhibition, (ITEX), 20 -22 May 2004, Kuala Lumpur.

2004

24. Silver Medal Tang TH, Musa M, Ravichandran M, Suwaibah S, Abdah Karimah CMN, Owi BT, Lee Su Yin, NIk Norliza, Wan Adibah WA, NH and Zainul ZF.

EZTB AMP PCR Detection Kit. International Invention, Innovation, Industrial Design & Technology Exhibition (ITEX), 20-22 May 2004, Kuala Lumpur.

2004

25. Gold Medal, WIPO Gold Medal, KASS Award Yap Yoke Yeow, Melissa Chan

Li Ann, Lee Su Yin, M. Ravichandran, Shahid Hassan. EZEBV Amp: A DNA

based diagnostic kit for detection of Epstein-Barr virus in Nasopharyngeal carcinoma (NPC). International Invention, Innovation, Industrial Design & Technology Exhibition (ITEX), 20 -22 May 2004, Kuala Lumpur.

2004


2004

27. Silver Medal, M. Ravichandran,Nur Haslindawaty A.R, Atif Ali,S, Goh Lai Kuan, Kurunathan, S, Melissa Chan Li Ann, Atif Amin Baig, P. Lalitha and Zainul F Zainuddin. Innovative oral cholera vaccine prototype developed by genomic technology. Invention & Innovation Competition 2004, Organised by Ministry of Science, Technology & Innovation, Malaysia (MOSTI), Putra World Trade

2004


Centre, Kuala Lumpur, Malaysia, 27 – 29 August 2004.

28. Malaysia Toray Science Foundation Science and Technology Award Asma Ismail, Ravichandran M, Ong Kohk Hai, Zainoodin Sa Kadher, Mohd Zaki Salleh 2003. In recognition of outstanding achievements in Medical Microbiology, Medical Biotechnology, Rapid diagnosis of infectious diseases on typhoid and paratyphoid fevers, Development of new technology platforms for rapid diagnosis of diseases

2003

29. Best Lecturer award, 2003, School of Health Sciences, Universiti Sains Malaysia

2003


2003

31. Gold Medal Asma Ismail, Ravichandran M, Aziah Ismail and Foong Sui Yun , TYPHI RAPID, 14th International invention, Innovation, Industrial design and Technology Exhibition (ITEX), 15-18th May 2003, Sunway Convention Centre, Kuala Lumpur, Malaysia

2003

32. Silver Medal P. Lalitha, M. Ravichandran , Teoh Pick Har, Lee Su Yin, Lim Kun Lee, NurHaslindawaty A R, Mohd Zaki Salleh, Asma Ismail, Zainuddin Z F, Cholera DNA Rapid. 14th International invention, Innovation, Industrial design and Technology Exhibition (ITEX), 15-18th May 2003, Sunway Convention Centre, Kuala Lumpur, Malaysia

2003

33. Best Presentation for Scientific & Clinical Papers Zunaina E, Wan Hazabbah WH, Raja Azmi MN, Asokumaran T, Hasnan M, Zainul F.Z, Ravichandran M. Evaluation of PCR Method To Detect Fungal Pathogens In Microbial Keratitis. at 21st M'sia-S'pore Opthalmic Congress at the Andaman, Datai Bay, Langkawi on 20th to 22nd June 2003.

2003

34. Silver Medal M. Ravichandran, P. Lalitha, Lee Su Yin, Lim Kun Lee, Melissa Chan Li Ann, Syed Atif Ali, Kurunathan S. , Nor Hayati Ismail. EZDNA Amp: Thermostabilized reagents for in vitro amplification of DNA, EXPO Science and Technology 2003, Organised by Ministry of Science, Technology & the Environment of Malaysia (MOSTE), Putra World Trade Centre, Kuala Lumpur, Malaysia, 7-9 August 2003.

2003

35. Anugerah Merit: Ravichandran, M., Atif Ali, S., Nur Haslindawaty A.R., Lai C.T., Chan Y Y, Lalitha, P., Zainuddin, Z.F. 2003. A Genetically Engineered, Non-Toxic and Environmentally Safe Vaccine Strain (VCUSM1) for Cholera. Pameran Penyelidikan, Kategori Genetik Mikrob, Pameran Penyelidikan dan Pembangunan IPTA 2003.

2003

36. Gold Medal Asma Ismail, Ravichandran M, Aziah Ismail and Foong Sui Yun, “TYPHIRAPID M: Rapid 15 minute IgM test for the acute diagnosis of typhoid fever”. International Exhibition "Ideas Inventions New Products" (IENA), October 30 to November 2, 2003, Nuremberg Germany

2003

37. Best Poster Award, Atif Ali S, Kurunathan S, Nur Haslindawaty A R, Chan Y Y, Lalitha P, Zainuddin Z F and Ravichandran M „Safety And Immunogenicity of Oral Auxotrophic Cholera Vaccine Candidates‟. 14th National Biotechnology Seminar Universiti Sains Malaysia Penang Dec 10-13th 2003

2003

38. Outstanding Project Award, Second prize Development of a Genetically Engineered, Orally Administrable, Live Cholera Vaccine against Vibrio cholerae

2003


O139 Bengal, Given by Universiti Sains Malaysia, 18 December 2003.

39. Pensyarah Contoh, Academic year 2003/4, School of Health Sciences, Universiti Sains Malaysia, 10 December 2003.

2003

40. Best Presentation Award Kirnpal-Kaur B.S, Mohd Zaki Salleh, Ravichandran M., Asma Ismail. Identification of specific primers for Shigella flexneri. 25th Malaysian Microbiology Society Symposium and 5th UNESCO National Workshop for the Promotion of Microbiology in Malaysia, 8-11 September 2002. Kota Bharu, Kelantan, Malaysia

2002

41. Best Presentation Award Atif Ali, S, Nur Haslindawaty, A.R , Lai, C.T, Afifi, S.A.B., Lalitha, P, Zainuddin, Z.F and Ravichandran M. Evaluation of a live oral attenuated cholera vaccine for Vibrio cholerae O139 Bengal. 25th Malaysian Microbiology Society Symposium and 5th UNESCO National Workshop for the Promotion of Microbiology in Malaysia, 8-11 September 2002. Kota Bharu, Kelantan, Malaysia

2002

42. Gold Medal: Asma Ismail, Ravichandran M, Aziah Ismail and Foong Sui Yun, “TYPHIRAPID M: Rapid 15 minute IgM test for the acute diagnosis of typhoid fever” Expo Science & Technology 2002, 2-4 November 2002, Putra World Trade Centre, Malaysia

2002

43. Best Presentation Award at 34th Annual scientific seminar on Impact of development of tropical diseases, Malaysian Society of Parasitology and Tropical Medicine, 20-21 March 1998, Selangor, Malaysia.

1998

44. WPSC Young Investigator Award at the 6th Western Pacific Congress of Chemotherapy and Infectious Diseases, 29 Nov- 3 Dec, 1998 at Kuala Lumpur

1998

45. Young Scientist Travel Award received to attend the "XIV International Congress for Tropical Medicine and Malaria", at Nagasaki, Japan 17-22 Nov'96.

1996

6. QUALITY MANAGEMENT other qualifications

5. GCP - Good Clinical Practice, October 2003. Clinical Trial Unit, Universiti Sains Malaysia.

6. ISO 9001:2000, Certified Lead Auditor, 30 March 2005.

7. ISO 9001:2000, Academic Program, Document Controller, Dept. Microbiology, School of Medical Sciences, USM (present)

8. ISO15189 Deputy Quality Manager, Dept. Microbiology, School of Medical Sciences, USM

9. “ISO 9001:2008 Auditor Training” by SIRIM Training Services Sdn Bhd on 24-25 April 2012.

10. “Internal Audit MS ISO 9001:2008” by SIRIM Training Services Sdn Bhd on 20-21 November 2013.


7. RESEARCH PUBLICATIONS IN JOURNALS

No Publications

Impact

Factor * Citations**

1. Prabhakaran G, Subhash Bhore J and Ravichandran M. Development and Evaluation of Poly Herbal Molluscicidal Extracts for Control of Apple Snail (Pomacea maculata). Agriculture 2017, 7(3), 22

2. BangaSingh K, Nisha M, Lau H, Ravichandran M, Salleh M Alteration in apyrase enzyme attenuated virulence of Shigella flexneri. Microbial pathogenesis.2016 vol: 91 pp: 123-8

2.0

3. Heera, Rajandas, Parimannan Sivachandran, Suresh V. Chinni, Joanne Mason, Larry Croft, Manickam Ravichandran, and Lee Su Yin. 2015. “Efficient Extraction of Small and Large RNAs in Bacteria for Excellent Total RNA Sequencing and Comprehensive Transcriptome Analysis.” BMC Research Notes 8 (1). doi:10.1186/s13104-015-1726-3.

4. Singh KK, Nisha M, Yee LH, Ravichandran M, Salleh MZ.Alteration in apyrase enzyme attenuated virulence of Shigella flexneri. Microb Pathog. 2015 Dec 16. pii: S0882-4010(15)30085-1. doi: 10.1016/j.micpath.2015.12.004.

2.0

5. Perumal, Veeradasan, Uda Hashim, Subash C. B. Gopinath, R. Haarindraprasad, P. Poopalan, Wei-Wen Liu, M. Ravichandran, S. R. Balakrishnan, and A. R. Ruslinda. 2015. “A New Nano-worm Structure from Gold-nanoparticle Mediated Random Curving of Zinc Oxide Nanorods.” Biosensors & Bioelectronics 78 (October): 14–22. doi:10.1016/j.bios.2015.10.083.

5.361 2

6. Liew, P. S., Lertanantawong, B., Lee, S. Y., Manickam, R., Lee, Y. H., & Surareungchai, W. (2015). Electrochemical genosensor assay using lyophilized gold nanoparticles/latex microsphere label for detection of Vibrio cholerae. Talanta, 139, 167–173. doi:10.1016/j.talanta.2015.02.054

3.733 8

7. Al-Fendi, Ali, Rafidah Hanim Shueb, Manickam Ravichandran, and Chan Yean Yean. 2014. “Isolation and Characterization of Lytic Vibriophage against Vibrio Cholerae O1 from Environmental Water Samples in Kelantan, Malaysia.” Journal of Basic Microbiology, February, doi:10.1002/jobm.201300458.

1.198 2

8. Murugaiah, Chandrika, Nik Zuraina Nik Mohd Noor, Shyamoli Mustafa, Ravichandran Manickam, and Lalitha Pattabhiraman. "Construction and Evaluation of V. cholerae O139 Mutant, VCUSM21P, as a Safe Live Attenuated Cholera Vaccine." PLOS ONE 9, no. 2 (2014): e81817.

3.73 1

9. Chin Kuan, Guan, Liew Pei Sheng, Patsamon Rijiravanich, Kasi Marimuthu, Manickam Ravichandran, Lee Su Yin, Benchaporn Lertanantawong, and Werasak Surareungchai. 2013. “Gold-nanoparticle Based Electrochemical DNA Sensor for the Detection of Fish Pathogen Aphanomyces Invadans.” Talanta. 2013 Dec 15;117:312-7. Epub 2013 Sep 19.

3.733 0


No Publications

Impact


doi:10.1016/j.talanta.2013.09.016.

10. Hassanain Al-Talib, Chan Yean Yean, Alyaa Al-Kh ateeb and Manickam Ravichandran. Comparative Evaluation of Three Different Methods of Genomic DNA Extraction for Staphylococcus aureus. World Applied Sciences Journal 21 (3): 424-427, 2013

0 2

11. Hassanain Al-Talib , Chan Yean Yean , Alyaa Al-Khateeb , Habsah Hassan , Manickam Ravichandran. Rapid detection of methicillin-resistant Staphylococcus aureus by a newly developed dry reagent-based polymerase chain reaction assay.Journal of Microbiology, Immunology and Infection (2013) (August 5).doi:10.1016/j.jmii.2013.06.004

0.987 3

12. Hassanain Al-Talib, Chan Yean Yean, Habsah Hassan, Nik Zuraina NMN. and Manickam Ravichandran. Methicillin-Resistant Staphylococcus aureus Nasal Carriage Among Patients and Healthcare Workers in a Hospital in Kelantan, Malaysia. Polish Journal of Microbiology 2013, Vol. 62, No 1, 109–112

0.76 1

13. Rajandas H, Parimannan S, Sathasivam K, Ravichandran M, Yin LS. A novel FTIR-ATR spectroscopy based technique for the estimation of low-density polyethylene biodegradation. Polymer Testing 31 (2012) 1094–1099.

1.608 9

14. M. Marini, T.H. Sasongko, M.S. Watihayati, A.B. Atif, F. Hayati and Gunadi. Z.A.M.H. Zabidi-Hussin, M. Ravichandran, H. Nishio & B.A. Zilfalil. Allele-specific PCR for a cost-effective & time-efficient diagnostic screening of spinal muscular atrophy. Indian J Med Res 135, January 2012, pp 31-35.

1.826 2

15. D. Sugumar, L. X. Kong, Asma Ismail, M. Ravichandran, and Lee Su Yin. Rapid multi sample DNA amplification using rotary-linear polymerase chain reaction device (PCRDisc). Biomicrofluidics 2012 Mar;6(1):14119-1411913.

3.896 2

16. Nagaya D, Ramanathan S, Ravichandran M and Navaratnam V. A118G MU opioid receptor polymorphism among drug addicts in Malaysia. Journal of Integrative Neuroscience, 2012 Mar;11(1):117-22.

1.29 6

17. Sasidharan, S., Ghayethry, B., Ravichandran, M., Latha, L.Y., Lachumy, S.J., Leng, K.M., Rao, S.G.S. Prevalence of Helicobacter pylori infection among patients referred for endoscopy: Gender and ethnic differences in Kedah, Malaysia (2012) Asian Pacific Journal of Tropical Disease, 2 (1), pp. 55-59.

0.172 8

18. Yu, C. Y., G. Y. Ang, A. L. Chua, E. H. Tan, S. Y. Lee, G. Falero-Diaz, O. Otero, I. Rodríguez, F. Reyes, A. Acosta, M. E. Sarmiento, S. Ghosh, T. Ramamurthy, C. Yean Yean, P. Lalitha & M. Ravichandran. Dry-reagent gold nanoparticle-

2.018 17


No Publications

Impact


based lateral flow biosensor for the simultaneous detection of Vibrio cholerae serogroups O1 and O139. Journal of Microbiological Methods, 86 (2011) 277–282; doi: 10.1016/j.mimet.2011.04.020

19. Shamini G, Ravichandran M, Sinnott JT, Somboonwit C, Sidhu HS, Shapshak P, Kangueane P.Structural inferences for Cholera toxin mutations in Vibrio cholerae. Bioinformation. 2011 Mar 2;6(1):1-9.

0 0

20. Chua AL, Elina HT, Lim BH, Yean CY, Ravichandran M, Lalitha P. Development of a dry reagent-based triplex PCR for the detection of toxigenic and non-toxigenic Vibrio cholerae. Journal of Medical Microbiology. 2011 Apr;60(Pt 4):481-5.

2.38 17

21. Chua, A.L.,Yean, C.Y., Ravichandran, M., Lim, B.H., Lalitha,

P., A rapid DNA biosensor for the molecular diagnosis of

infectious disease, Biosensors and Bioelectronics

2011,26(9):3825-3831

5.361 32

22. Sasidharan, S., Lachumy, S.J.T., Ravichandran, M., Latha,

L.Y., Gegu, S.R.S. Epidemiology of Helicobacter pylori among

multiracial community in Northern Peninsular, Malaysia: Effect

of age across race and gender 2011 Asian Pacific Journal of

Tropical Medicine 4 (1), pp. 72-75

0.172 12

23. Hassanain Al-Talib, Habsah Hasan, Chan Yean Yean, Sami

M. Al-Ashwal, Manickam Ravichandran. Fatal necrotizing

pneumonia caused by Panton–Valentine leukocidin producing

hospital-acquired Staphylococcus aureus: A case report.

Japanese Journal of Infectious Diseases. 2011;64(1):58-

60.

1.367 4

24. Chan M, Gim Cheong Tan, Kurunathan Sinniah, Chandrika

Murugaiah, LedonTalena, Fando Rafael, Lalitha P,

Ravichandran M. (2010)Construction and characterization of

an auxotrophic ctxA mutant of O139 Vibrio cholerae.

Microbial Pathogenesis:49(5):211-6.

2.0 3

25. D. Sugumar, Asma Ismail, Manickam Ravichandran, Ismail

Aziah & L. X. Kong. Amplification of SPPS150 and Salmonella

typhi DNA with a high throughput oscillating flow polymerase

chain reaction device. Biomicrofluidics 4, 2010 May 3;4(2).

pii: 024103.

3.896 3

26. Cheong TG, Ann MCL, Sinniah K, Ali SA, Ning TZ, Zainul ZF,

Lalitha P & Ravichandran M (2010) Construction and

characterization of rtxA and rtxC mutants of auxotrophic O139

Vibrio cholerae. Microbial. Pathogenesis. 48, 85–90,

doi:10.1016/j.micpath.2009.11.001

2.0 2


No Publications

Impact


27. Hassanain Al-Talib, Chan Yean Yean, Alyaa Al-khateeb, Kirnpal-Kaur Banga Singh , Habsah Hasan, Karim Al-Jashamy and Manickam Ravichandran. Comparative Evaluation of Five Culture Media with Triplex PCR Assay for Detection of Methicillin-Resistant Staphylococcus aureus. Current Microbiology 2009 Dec 24, DOI 10.1007/s00284-009-9567-8

1.51 6

28. Deris, Z.Z, Leow, V.M, Wan Hassan, W.M.N, Nik Lah, N.A.Z, Lee, S.Y, Siti Hawa, H, Siti Asma, H and Ravichandran, M. 2009. Non-O1, non-O139 Vibrio cholerae bacteraemia in splenectomised thalassaemic patient from Malaysia. Tropical Biomedicine 26(3): 320–325.

0.581 8

29. Raabe CA, Sanchez CP, Randau G, Robeck T, Skryabin BV,

Chinni SV, Kube M, Reinhardt R, Ng GH, Manickam R,

Kuryshev VY, Lanzer M, Brosius J, Tang TH &

Rozhdestvensky TS. A global view of the nonprotein-coding

transcriptome in Plasmodium falciparum. Nucleic Acids

Research, 2009, 1–10 doi:10.1093/nar/gkp895

7.836 8

30. Al-Talib H, Yean CY, Al-Khateeb A, Hassan H, Singh KK, Al-Jashamy K, Ravichandran M. A pentaplex PCR assay for the rapid detection of methicillin-resistant Staphylococcus aureus and Panton-Valentine Leucocidin. BMC Microbiology. 2009 May 28;9:113.

2.960 36

31. Siti Asma H, Mahiran Mustafa, YY Chan, Shukri Abdullah, AR

Zaidah, AR Nurhaslindawati, A Sarimah and M

Ravichandran. 2009. Pneumocystis pneumonia among HIV

patients in Malaysia. Southeast Asian J Trop Med Public

Health. 40: 6, 1293-97

0 1

32. Deris, Zakuan Zainy, Hans Van Rostenberghe, Hassan

Habsah, Ramli Noraida, Gin Ceong Tan, Yean Yean Chan,

Abdul Rahman Rosliza, and Manicham Ravichandran. “First

isolation of Burkholderia tropica from a neonatal patient

successfully treated with imipenem.” International Journal of

Infectious Diseases 2010 Jan;14(1):e73-4. Epub 2009 May

23.

2.529 5

33. Atif Amin, Atif Ali, Sinnah Kurunathan, Tan Gim Cheong, Karim Alwan Al-Jashamy, Hasnan Jaafar, Zainul F. Zainuddin, Manickam Ravichandran, Pattabhiraman Lalitha. Comparison of histopathological features of Vibrio cholerae O1 El Tor and O139 Bengal infection in rabbit intestinal mucosa . Histology and Histopathology (2009) 24: 559-565

2.502 0

34. P. Lalitha, M.N. Siti Suraiya, K.L. Lim, S.Y. Lee, A.R. Nur Haslindawaty, Y.Y. Chan, Asma Ismail, Zainul F. Zainuddin, M. Ravichandran. Analysis of lolB gene sequence and its use in the development of a PCR assay for the detection of Vibrio cholerae. Journal of Microbiological Methods (2008) 75: 142-4.

2.018 8


No Publications

Impact


35. Shawarinin J, Effat O, Ravichandran M and Mohtar Ibrahim. Fusarium sp in severe contact lens related fungal keratitis. International Journal of Opthalmology 2008; 8(4):661-669

0 3

36. Zunaina Embong, Wan Hazabbah Wan Hitam, Chan Yean Yean, Nur Haslindawaty Abdul Rashid, Balqis Kamarudin, Siti Khaironi Zainal Abidin, Sabariah Osman, Zainul F Zainuddin and Manickam Ravichandran Specific detection of fungal pathogens by 18S rRNA gene PCR in microbial keratitis. BMC Ophthalmology. 2008 Apr 29;8(1):7, doi:10.1186/1471-2415-8-7

1.38 8

37. AR Zaidah, YY Chan, H Siti Asma, Shukri Abdullah , AR Nurhaslindawati, Mustafa Salleh, M Zeehaida, P Lalitha, Mahiran Mustafa and M Ravichandran. Detection of Cryptosporidium parvum in HIV-infected patients In Malaysia using a molecular approach. Southeast Asian J Trop Med Public Health. 3 May 2008, 39(3), 511-516

0 7

38. Chan YY, Balqis Kamarudin, Ozkan, DA, Lee SY,Lalitha P, Ismail, A, Mehmet Ozsoz and Ravichandran, M. A rapid enzyme-linked amperometric electrochemical genosensor assay for the detection of PCR amplicons on a streptavidin-treated screen-printed carbon electrode. Analytical Chemistry, Apr 15, 2008, 80(8):2774-9.

5.874 6

39. Gopinath VK, Pang Yoong T, Chan Y Y, Ravichandran M. Identifying polymorphism in enamelin gene in amelogenesis imperfecta (AI). Archives of Oral Biology. 2008 Oct;53(10):937-40. Epub 2008 May 8.

1.655 4

40. Chan Y Y, Mohd Hafiz B A N, Mohd Azli B Y, Noor Mohamad A B S, Azril Deenor B M D, Abd Majid B M and Ravichandran M. Low prevalence of vancomycin- and bifunctional aminoglycoside-resistant enterococci isolated from poultry farms in Malaysia. International Journal of Food Microbiology 2008, 122: 221–226 doi:10.1016/j.ijfoodmicro. 2007.11.063

2.61 4

41. Chan YY, Su Yin L, Lalitha P and Ravichandran M. A Nanoplex PCR Assay for the Rapid Detection of Vancomycin and Bifunctional Aminoglycoside Resistance Genes in Enterococcus Species. BMC Microbiology 2007 Dec 11;7(1):112, doi:10.1186/1471-2180-7-112.

2.960 9

42. Shareef, BT, Harun, A, Roziawati, Y, Shaiful Bahari, I, Deris, ZZ, Ravichandran M. Recurrent Trichosporon asahii glossitis: A case report. Journal of Contemporary Dental Practice, 2008, March, (9)3:114-120

0

2

43. Aziah Ismail, Manickam Ravichandran, Asma Ismail, Amplification of ST50 gene using dry-reagent–based polymerase chain reaction for the detection of Salmonella

2.426 9


No Publications

Impact


Typhi. Diagnostic Microbiology and Infectious Disease 2007, 59: 373–377.

44. Sosroseno W, Musa M, Ravichandran M, Ibrahim MF, Bird PS, Seymour GJ. Effect of inhibition of inducible nitric oxide synthase (iNOS) on the murine splenic immune response induced by Aggregatibacter (Actinobacillus) actinomycetemcomitans lipopolysaccharide. European Journal of Oral Sciences. 2008 Feb ;116(1):31-36.

1.890 6

45. Sosroseno W, Musa M, Ravichandran M, Fikri Ibrahim M, Bird PS, Seymour GJ J Effect of l-N(6)-(1-iminoethyl)-lysine, an inducible nitric oxide synthase inhibitor, on murine immune response induced by Actinobacillus actinomycetemcomitans lipopolysaccharide. Journal of Periodontal Research. 2007 Apr;42(2):124-30.

2.128 6

46. Yoke-Yeow Yap, Shahid Hassan, Melissa Chan, Pua Kin Choo, Manickam Ravichandran. Epstein-Barr virus DNA detection in the diagnosis of nasopharyngeal carcinoma. Otolaryngology Head and Neck Surgery, 2007 Jun;136(6):986-91.

1.565 8

47. Min TH, Khairul MF, Low JH, Che Nasriyyah CH, A'shikin AN, Norazmi MN, Ravichandran M, Raju SS. Roxithromycin potentiates the effects of chloroquine and mefloquine on multidrug-resistant Plasmodium falciparum in vitro. Experimental Parasitology. 2007 Apr;115(4):387-92.

1.869 6

48. Sosroseno W, Musa M, Ravichandran M, Fikri Ibrahim M, Bird PS, Seymour GJ. The role of cyclic-AMP on arginase activity by a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans. Oral Microbiology Immunology. 2006 Dec;21(6):347-52.

2.479 4

49. Khairul MF, Min TH, Low JH, Nasriyyah CH, A'shikin AN, Norazmi MN, Ravichandran M, Raju SS. Fluoxetine Potentiates Chloroquine and Mefloquine Effect on Multidrug-Resistant Plasmodium falciparum in vitro. Japanese Journal of Infectious Diseases, 59 (5), 329-331, 2006

1.367 5

50. Sosroseno W, Musa M, Ravichandran M, Fikri Ibrahim M, Bird PS, Seymour GJ. Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans. Oral Microbiology Immunology. 2006 Jun;21(3):145-50.

2.479 5

51. Francis, A, Aiyar, S , Chan, Y. Y , Lin, N and Ravichandran, M. An improved selective and differential medium for the isolation of Burkholderia pseudomallei from clinical specimens. Diagnostic Microbiology and Infectious Disease 55; 95–99

2.426 5


No Publications

Impact


(2006)

52. Ravichandran M , Atif Ali S , Nur Haslindawaty AR, Kurunathan S, Chan Y Y , Lai C T , Afifi Sheikh A B , Lalitha P ,and Zainuddin Z F. Construction and Evaluation of O139 Vibrio cholerae Vaccine Candidate Based on hemA Gene Mutation. Vaccine. 2006,24(18): 3750-3761

3.572 4

53. Kangueane P, Sakharkar MK, Rajaseger G, Bolisetty S,Sivasekari B, Zhao B, Ravichandran M, Shapshak P, Subbiah S. 2005. A Framework To Sub-Type HLA Supertypes. Frontiers In Bioscience 10, 879-886, January 1, 2005

4.048 8

54. Yap YY, Shahid H, Ravichandran M, Pua KC. 2004 Diagnosis of Nasopharyngeal carcinoma by DNA Amplification of EBV Genomes in Nasopharyngeal Biopsy and Fine-Needle aspiration of Neck Nodes. 10 Asia-Oceania ORL Head and Neck congress, 22 - 26 February 2004, The Medical Journal of Malaysia, 9: Suppliment A, 160-1

0 0

55. Low Jen Hou, Raju S. Sivachandra, Abdullah M. Shukri, Norazmi M. Nor and Ravichandran M., Rifampicin Antagonizes the Effectiveness of Chloroquine on Chloroquine Resistant Plasmodium berghei in mice, Japanese Journal of Infectious Diseases, 2004 Oct;57(5):198-202.

1.367 6

56. Gopinath V.K., Karima Akool M. A. S., Chan Y. Y., Melissa Chan L. A., Ravichandran M. Amelogenesis Imperfecta: Enamel Ultra Structure And Molecular Studies. Journal of Clinical Pediatric Dentistry 28 (4): 319-22 2004

0.474 3

57. Paneerchelvam S., Nur Haslindawaty, Ravichandran M., Norazmi M N and Zainuddin Z.F.. Allele frequency distribution for 10 STR loci in the Malay population of Malaysia. Journal of Forensic Sciences : 48(2): 1-2 2003

1.159 4

58. Suba S., Ravichandran. M., Lalitha P., Narayanan R.B., Jayaraman K., Boothby J.T and Kaliraj P. Diethylcarbamazine (DEC) therapy and modulation of immune response in microfilaraemics with Wuchereria bancrofti infection. Biomedical Research 11(3) 321-325 2000

0 2

59. Ravichandran, M., Doolan D. L., Janet Cox-Singh., Hoffman S. L., Singh B.HLA Degenerate T-cell epitopes from Plasmodium falciparum liver stage-specifc antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas. Parasite Immunology, 2000: 22: 469-473

2.357 4

60. Lalitha P., Ravichandran. M., Suba S., Kaliraj P., Narayanan R B., and Jayaraman K. Quantitative assessment of circulating antigens in Human Lymphatic Filariasis; a field evaluation of monoclonal antibody-based ELISA using blood collected on filter strips. Tropical Medicine and International

2.841 26


No Publications

Impact


Health 1998: 3 (1):41-45.

61. Ravichandran. M., Regunathan. J., Narayanan. R. B., Jayaraman K and Kaliraj.P. Modulation of cellular immune response by cytokines in bancroftian filariasis. Indian Journal of Clinical Biochemistry 1997 12 (Suppl) 9-11.

0 0

62. Ravichandran M, Mahanty S, Kumaraswami.V, Nutman T. B and Kunthala Jayaraman. Elevated IL-10 mRNA expression and downregulation of Th1 type cytokines in microfilaremic individuals with Wuchereria bancrofti infection. Parasite Immunology 1997:19; 69-77.

2.357 45

63. Mahanty S, Ravichandran M, Uma R, Kunthala Jayaraman, Kumaraswamy V, and Nutman T. B. Regulation of parasite antigen-driven immune response by Interleukin-10 (IL-10) and IL-12 in lymphatic filariasis. Infection Immunity, 1997; 173: 1742-1747.

4.098 68

64. Mahanty S, Mollis S. N, Ravichandran M, Abrams J. S, Kumaraswamy V, Kunthala Jayaraman, Ottesen E. A and Nutman T. B. High levels of spontaneous and parasite antigen driven IL-10 production are associated with antigen specific hyporesponsiveness in human lymphatic filariasis. Journal of Infectious Diseases, 1996; 173: 769-73.

6.288 109

65. Mahanty.S, Mollis S, Ravichandran M, Jayaranman K, Kumaraswamy V, Abrams J.S, Ottesen E.A, Nutman T.B. Excess IL-10 production by peripheral blood mononuclear cells is associated with antigen specific hyporesponsiveness in human lymphatic filariasis. Clinical Research 1993. Vol 41 N0 2, p324.

0 0

Total 131.093 584 *JCR 2012 edition, **Scopus updated Aug16

7.1 Research publications in Book

1. Ravichandran M, Jayarani R, Kaliraj P and Kunthala Jayaraman. Studies On the role of cytokines in the differential immune and cellular responses of peripheral lymphocytes in Bancroftian filariasis and their application in the development of Immunoprophylaxis, published in the book "Vaccines 96: Molecular approaches to the control of Infectious diseases"Cold Spring Harbour Laboratory ISBN 0-87969-479-3.

2. Chapter expert: Technology Foresight Study on in vitro Diagnostics Sector conducted by Dr. Syamala Ariyanchira for Malaysian Biotechnology Corporation, Malaysia.

3. Chapter expert: Technology Foresight Study on Vaccine Sector conducted by Dr. Syamala Ariyanchira for Malaysian Biotechnology Corporation, Malaysia.


4. Chan Yean Yean, Lee Su Yin and Manickam Ravichandran (2012) Electrochemical Genosensor Assay for the Detection of Bacteria on Screen-Printed Chips. In: Ozsoz, Mehmet, ed. Electrochemical DNA Biosensors, Pan Stanford Publishing, 481-493 (ISBN:10-9814241776)

7.2 Publication in the Web site

1. M. Ravichandran and Zainul F Zainuddin, 2002. Cloning Simulation Group Project.

http://www.ppsk.usm.my/lecturers/mravi/CSP2002/index.htm

8. MEDIA REPORTS

1. “Made in Malaysia: Diagnostic Kits, BiCalert” , Malaysian Biotechnology Information Centre (MABIC). 15 May 2005

2. “ Innovations on cholera diagnosis and vaccine‟ Frontiers, USM. 2004

3. „Potential oral cholera vaccine developed by USM‟ The Star, 1 December 2004.

4. Saintis USM temui vaksin taun” Berita Harian, Front page, 26 September, 2002

5. “USM scientists come up with vaccine for two types of cholera , ”The New Strait Times, page 12, 26 September, 2002

6. “Vaccine for cholera strain discovered, The Star, 27 September, 2002

7. “Saintis USM temui vaksin taun” Bernama, 27 September, 2002

8. “Saintis USM Kubang Kerian temui vaksin baru taun” Utusan, Front page, 26 September, 2002

9. STUDENTS SUPERVISION/EXAMINATION

9. 1 Post graduate students

No Student Name Degree Title Supervision

1. G. Prabhakaran PhD

Development and Evaluation of Botanical

Molluscicides to control Pest Snails

Supervisor

2. Heera a/p Rajandas PhD

Isolation, molecular characterization and in silico analysis of polyethylene

degrading enzyme from soil microbe

Supervisor

3. Noor A‟shikin bt Azahri PhD

In-vitro screening for p-glycoprotein inhibitors by using OMP mutant E.coli model

system and chloroquine resistant Plasmodium falciparum cell line

Supervisor

4. Chan Yean Yean***

PhD Development of a Multiplex assay for rapid detection of Enterococcus spp. and its

antibiotic resistant using DNA biosensor

Supervisor

5. Robaiza Zakaria PhD Systemic search for novel small non- Supervisor

http://www.ppsk.usm.my/lecturers/mravi/CSP2002/index.htm



messenger RNAs in Salmonella typhi: An RNomic approach towards identifying potential drug targets and diagnostics

6. Hassanain I Yehya

Altalib

PhD Development of a cold chain free DNA – based rapid test for the early detection of

methicillin – resistant Staphylococcus aureus (MRSA) from clinical samples

Supervisor

7. Tan Gim Ceong PhD

Construction and characterization of rtxC mutant Vibrio cholerae O139: Towards

Understanding the Molecular Mechanisms of Enteropathogenesis

Supervisor

8. Syed Atif Ali *,*** PhD Development Of A Genetically Engineered

Orally Adminsterable Live Cholera Vaccine Against Vibrio cholerae O139 Bengal

Co-

supervisor

9. Kirnpal Kaur a/p Banga

Singh***

PhD Development of rapid diagnosis for Shigella flexneri: Genomic and Proteomic approach

Co-

supervisor

10. Lee Su Yin

PhD Development and Evaluation of a Novel Thermostabilized

Non-PCR Based System for the Rapid Diagnosis of Cholera

Co-

supervisor

11. Aziah Ismail*** PhD Development of DNA-based diagnostics for

the detection of Salmonella typhi and Salmonella paratyphi A

Co-

supervisor

12. Chua Ang Lim PhD Development of gold nanoparticle based

biosensor for the detection of Vibrio cholerae

Co -

supervisor

13. Chandrika Murgiah PhD Construction and evaluation of multigene mutant of V. cholerae 0139

Co -

supervisor

14. Hoe Chee Hock PhD

Experimental Rnomics based systemic search for small, non-protein coding RNA (npcRNA) riboswitches in Vibrio cholerae

towards discovering novel drug target, vaccine candidate and diagnostic marker

Co -

supervisor

15. Nur Haslindawaty bte

Abd Rashid ** MSc

Development and evaluation of an -amino levulinic acid (ALA) auxotroph of Vibrio

cholerae El Tor: Ogawa

Supervisor

16. Atif Amin Baig

MSc Mutational Analysis Of hap (Hemagglutinin/Protease) Gene in

-Aminolevulinic Acid (ALA) Auxotroph Of O139 Strain Of Vibrio cholera ;

Towards the Development Of Cholera Vaccine

Supervisor

17. Melissa Chan Li Ann

MSc Site Directed Mutation of ctx operon in VCUSM2, V. cholerae vaccine candidate

strain: Towards the development of a vaccine for cholera

Supervisor

18. Kurunathan MSc Evaluation Of Cholera Vaccine Candidates

Vcusm2 (El Tor), VCUSM3 (O139) And Its Supervisor



Bivalent Vaccine Formulation: Towards The Development Of Bivalent Vaccine For

Cholera

19. Heera A/P Rajandas MSc Isolation and Characterization of Plastic

Degrading Microorganisms Supervisor

20. Alex Lourdes Francis a/l

SM Francis

MSc Development And Evaluation Of A Selective Medium For The Isolation Of Burkholderia

Pseudomallei.

Co-

supervisor

21. Lim Kun Lee

MSc Development Of A DNA Based Molecular Method For The Detection Of Biotype, Virulence And Antibiotic Resistance

Genotype Of Vibrio Cholerae.

Co-

supervisor

22. Low Jen Hou MSc

Effect of chemosensitizers on chloroquine-resistant plasmodia in vitro and in vivo

Co-

supervisor

23. Tan Hooi Min

MSc Effect of p-Glycoprotein inhibitors on Mefloquine resistant Malaria model system

in vitro and in vivo: Towards identifying chemosensitizers for Malaria.

Co-

supervisor

24. Khairul Mohd Fadzli Bin

Mustafa

MSc Effect of p-Glycoprotein inhibitors on Chloroquine resistant Malaria in vitro and in

vivo: Towards identifying effective chemosensitizers for Malaria.

Co-

supervisor

25. Abdah Karimah binti Che

Md Nor

MSc Development of a thermostabilized multiplex

DNA detection method for tuberculosis

Co-

supervisor

26. Thiruchelvan Nadarajan

****

MSc Development of a thermostabilized multiplex DNA detection method for enteric pathogens

Co –

supervisor

27. Nasriyyah Binti Che

Husin

MSc The screening of Malaysian Medicinal plant for antimalarial and chloroquine/Mefloquine

resistance reversal activities

Co –

supervisor

28. Marini Marzuki MSc

Development of EZ

DNA Diagnostic Kit for the Detection of Homologous Deletion of the

SMN1 Gene in Spinal Muscular Atrophy (SMA) Patients

Co –

supervisor

29. Aniza Binti Rahumatullah

MSc Development of realtime PCR and

thermostabilized PCR for the diagnosis of toxaplasmosis

Co –

supervisor

30. Nurazwana Zakaria

MSc Evaluation of prime boosting immunization

strategy using newly constructed Tuberculosis vaccine candidates in mice

Co –

supervisor

31. Sarah Stephanie John Sandanaraj

M.Sc Generation And Characterization Of Xerc Mutant Of O139 Vibrio Cholerae By Λ Red Recombination System

Supervisor

32. Ms. Fong Yee Shiuan

M.Sc Construction of non-toxigenic O1 El Tor serogroup V. cholerae vaccine candidate

Supervisor

33. Sasireigga Jaya Jothi MSc Isolation and Characterization against

Dickeya chrysanthemi: Towards Supervisor



Biocontrol of Macergen Investigation

34. Vickneswaran Narayana

Murthy

MSc Isolation, Molecular characterization and application of lytic bacteriophages as

biocontrol agent

Supervisor

35. Ng Sze Huan MSc Product and process validation for cold

chain free live attenuated cholera vaccine Supervisor

36. Dr Zaidah Ab Rahman M Med

Path

Comparison of Microscopy, PCR and Rapid Immunoassay Test for Detection of Cryptosporidium parvum in Fecal

Specimens of HIV infected patients

Supervisor

37. Dr Siti Asma M Med

Path

Comparison of Microscopy and PCR test in the detection of Pneumocyctis carinii in HIV infected patients admitted at hospital Kota

Bharu

Supervisor

38. Dr Siti Suraiya Md Noor M Path PCR Method Targeted to the Novel Non-

Virulent Gene for detection of Vibrio cholerae

Supervisor

39. Dr Yap Yoke Yeow*** M Med (ORL)

Diagnosis of NPC by DNA amplification of EBV genomes in tissue obtained by biopsy

and fine needle aspirate Supervisor

40. Dr. Zunaina Embong* M Med (Opthal)

Evaluation of PCR Method To Detect Fungal Pathogens In Microbial Keratitis

Supervisor

*Best presentation award, ** Out standing project award, ***Gold Medal for the product **** Young Investigator award (details please see section (Section 5)


9.2. Postgraduate degree thesis/Dissertation examination

No Name of

Candidate Title Institution*

Degree Date

1. Sugumar Dharmalingam

Design, fabrication and evaluation of universal polymerase chain reaction devices

Deakin University, Australia

PhD 2009

2. V, jayaraj Simulation studies on transcriptome and proteome

Bharathidasan University,

Trichy, INDIA PhD 2009

3. Venugopal Balakrishnan

Biochemical characterization of interaction between CTCF/YB-1 transcription factors with HPV16 and 18 E7 onchoprotein and their involvement during c-myc gene regulation in cell proliferation pathway

USM PhD 2009

4. Kanakeswary Karisnan

Bacillus thuringiensis 18 (Bt 18) parasporal proteins with antileukaemic activity: Purification, characterization and immunoassay detection

IMU MSc 2008

5. Dr Che Mahiran Che Daud

An experimental study on intrastromal injection of amphotericin B in Fusarium solani keratitis in rabbits

USM

Master of Medicine (Ophthalmology)

2008

6. Mohd Nizam bin Zahary

Clinical and Molecular genetics study of

prostaglandin F2 receptor gene in glaucomatous patients in Malaysia

USM

MSc 2008

7. Norhanani Mohd Redzwan

Immunological studies of DNA (pJWVacII) and surface display (r-STVacII) vaccine candidates expressing a synthetic multiepitope gene of Mycobacterium tuberculosis in a prime boost strategy using a mouse model

USM

MSc 2008

8. Nurulhasanah Othman

Construction of recombinant BCG expressing the VPI antigen of Enterovirus 71 in the development of a candidate vaccine

USM

MSc 2007

9. Dr. Wan Nor Azilah

Detection of Entamoeba histolytica derived lectin using the Tehlab Entamoeba histolytica II ELISA in sera of patients with suspected amoebic liver abscess in HUSM

USM

Master of Pathology

(Microbiology)

2007

10. Dr Cheong Min Tet

A study on the expression of HLA-DR on conjunctival epithelial cells in patients treated with topical latanoprost as adjunctive therapy and its association with prostanoid (FP) receptor polymorphisms

USM

Master of Medicine

(Ophthalmology)

2007

11. Ros Azeana Abdul Aziz

Characterization of the homologs of a diagnostically significant Brugia malayi gene (Bm17DIII) in Wuchereria bancrofti, Loa loa and Onchocerca volvulus

USM

MSc 2006

12. Ms. Lau Tiek Ying

The identification of unique molecular markers of Plasmodium vivax from Malaysian Borneo

UNIMAS MSc 2006

13. Patrick Guda AK Benjamen

Cholera Epidemic In Sarawak (1994-2003) and Molecular characterisation of

UPM MSc 2006


No Name of Candidate

Title Institution*

Degree Date

Vibrio cholerae isolated from recent outbreaks In Malaysia

14. Dr Chieng Lee Ling

Prostanoid (FP) receptor polymorphisms: The association of novel single nucleotide polymorphism with the responsiveness of glaucoma patients to topical latanoprost

USM

M Med (Ophthalmolo

gy)

2006

15. Dr Selva Raja Vengadasalam

The influence of beta2-adrenoreceptor polymorphisms on spirometric changes in glaucoma patients receiving topical Timolol-XE

USM

M Med (Ophthalmolo

gy)

2006

16. Mr. Lim Boon Huat

Molecular parasitological aspects of Brugia malayi filarial parasite

USM PhD 2005

17. Mr. David Perara

Characterization of an unusual Adenovirus strain Sibu 97

UNIMAS PhD 2005

18. Dr Wan Azman Bin Wan Sulaiman

Risk identification for msx-1 mutation in non syndromic cleft lip and palate deformities for the formulation of prevention starategies

USM

Master of Surgery (Plastic

Surgery)

2005

19. Mohd Izuan Othman

The allele and genotype variations of fifteen short tandem repeat (STR) loci in Malay, Chinese and Javanese groups of the Malaysian population

USM

MSc 2004

20. Zunaina Embong

Evaluation of PCR method to detect fungal aetiology in microbial keratitis USM

M Med (Ophthalmolo

gy)

2002

21. Noraini Ismail Demonstration of antigenic and specific whole cell proteins for MSSA and MRSA USM

Master of Pathology

(Microbiology)

2002

22. Dr. Habsah Hassan

Comparison between dot blot EIA and culture method for detection of Shigella flexneri in stool specimens

USM Master of Pathology

(Microbiology)

2002

* USM – Universiti Sains Malaysia, UPM – Universiti Putra Malaysia, UNIMAS – Universiti Malaysia Sarawak IMU – International Medical University

10. INVITED LECTURES

10.1 Plenary lectures

1. “DNA Amplification Technologies”, National Diagnostic Conference and Workshop, Renaissance Hotel, Kota Bharu, 5th October 2004.

2. “Molecular Diagnosis in Medicine” First National Conference on Medical Laboratory Sciences, Grand River View hotel, Kota Bharu, 7-9 November 2006.

3. Plenary Lecture - Endnote, Workshop on Scientific Writing “Write to Publish”, 20 – 21 December 2006, Perdana Hotel Kota Bharu, Kelantan

4. Plenery Lecture “Current trends in Molecular Diagnostics”, 3rd National Infectious Disease Conference 2009, Renaissance Hotel, Kota Bharu, 26 – 27 October 2009.

5. Plenery Lecture “Cholera vaccine: Where are we now?”, 3rd National Infectious Disease Conference 2009, Renaissance Hotel, Kota Bharu, 26 – 27 October 2009.


6. “Advances and Current progress in cholera vaccine development”, My Bio1 Conference 2010, 30-31 October 2010, Berjaya Time Square Hotel and Convention Centre, Kuala Lumpur, Malaysia.

7. “Robust diagnostic platforms for Low resource settings” 1st AMDI International Biohealth Science Conference (IBSC-2010). 29 November to 1 December 2010. Bayview Hotel, Pinang, Malaysia.

10.2 International lecture

1. “Advances in cholera vaccine technology”, Faculty of Pharmacy, Ege University, Izmir, Turkey, 14th April 2006.

2. “Cold chain free molecular diagnostics” Faculty of Pharmacy, Ege University, Izmir, Turkey, 14th April 2006.

3. “Electrochemical genosensors for the diagnosis of infectious diseases”. United States-Japan Cooperative Medical Science Program (CMSP) sponsored 14th International Conference on Emerging Infectious Diseases (EID) in the Pacific Rim. October 4-6, 2010 in Penang, Malaysia.

4. “Advances and Current progress in cholera vaccine development”, BIOTECHCELLENCE 2011, 24 - 27 February, 2011, Anna University, Chennai , India

5. “Robust diagnostic platforms for Low resource settings” Nestlé Purina PetCare Global Resources, Inc, St. Louis, MO, USA. 20 August 2010.

10.3 National Lectures

1. Lecture and Hands-on session on “Manuscript writing ” 29 July 2009, Clinical

Research Unit, Hospital Selayang, Malaysia. 2. Lecture and Hands-on session on “Electronic Bibliography: Software tools for

research and scientific writing ” 13-14, March 2008, Clinical Research Unit, Hospital Selayang, Malaysia.

3. Electronic Bibilography, Kursus Penilaian Tahap Kecekapan (PTK) ,Tahap 3, (Academic), 12– 26 Jun 2007, Health campus, USM

4. Introduction to EZDNA Amp – Technology Insight and Applications , CLSI Primer Design and Genome Mining , Requirements on Molecular Diagnosis Workshop on Application of Thermostabilized PCR Technology, 17-18 July 2007, INFORMM, Health campus, USM

5. Introduction to Endnote, Intensive course on “Basic statistics and Research Methodology” 22-26 July, Health Campus, USM.

6. Citation Technique & Introduction to EndNote , 3rd National Workshop on Scientific Writing, 28th- 30th August 2007, MIP laboratory, School of Medical Sciences, USM.

7. EndNote & Referencing CWYW (Cite While You Write), 3rd National Workshop on Scientific Writing, 28th- 30th August 2007, MIP laboratory, School of Medical Sciences, USM.

8. Lecture and Hands-on session on “Strategies to perform efficient literature search and Bibliography software” Annual meeting on National Eye Database (NED),19-22, November 2007, Pejabat Pakar, Hospital Selayang, Malaysia.

9. “Setting and Quality control of PCR” Human Genome Centre, 31 July 2007, Health Campus, USM.

10. “Advances in cholera vaccine”, INFORMM, 22nd March 2006.


11. “Electronic Bibliography” Penceramah Kursus Penilaian Tahap Kecekapan (PTK) TK3 (Akademik), MIP, USM Kampus Kesihatan, 12th June 2006.

12. “Introduction to Endnote” Intensive course on “Basic Statistics and Research methodology”, USM, Health Campus, 25th July 2006.

13. “Lecture and Hands-on on Endnote” 2nd Endnote and Manuscript writing workshop, MIP, Health Campus, USM, 4-5 December 2006.

14. “Manuscript submission” 2nd Endnote and Manuscript writing workshop,. Bilik Persidangan Utama,PPSK, Health Campus, USM, 4-5 December 2006

15. Plenary Lecture - Endnote, Workshop on Scientific Writing “Write to Publish”, Perdana Hotel Kota Bharu, Kelantan, 20 – 21 December 2006,

16. “Introduction to Endnote” Intensive course on Basic statistics and Research Methodology. July 24-28, 2005.

17. “Electronic Bibliography” Penceramah Kursus Penilaian Tahap Kecekapan (PTK) TK3 (Akademik), , Bilik Persidangan Utama, USM Kampus Kesihatan, 8th September 2005.

18. “E-Learning” Penceramah Kursus Penilaian Tahap Kecekapan (PTK) TK3 (Akademik), Bilik Persidangan Utama, USM Kampus Kesihatan, 8th September 2005.

19. “Electronic Bibliography” Penceramah Kursus Penilaian Tahap Kecekapan (PTK) TK3 (Akademik), Bilik Persidangan Utama, USM Kampus Kesihatan, 14th December 2005.

20. “Future trends in DNA technology” Certificate course on Basic Genetics & Molecular Biology and DNA profiling techniques. Jabatan Kimia, Kuala Lumpur, 7th January 2005,

21. “Types of article and Impact factor” at Manuscript Scientific writing workshop, Bilik Persidangan Utama, PPSK, 19th April 2005.

22. “Lecture and Hands on session on Endnote” at Endnote workshop, Bilik Persidangan Utama, PPSK, 18th April 2005

23. “Electronic Bibliography” 2nd Scientific writing workshop, , Primula Beach Resort, Kuala Terengganu, 17-19 June 2005

24. “Introduction to Endnote” Intensive course on Basic statistics and Research Methodology. July 24-28, 2005.

25. “Bioinformatics in Molecular Biology”, 1st National Workshop and Colloquium on Pharmacogenetics. DK 6 & INFORMM. 1st April 2004.

26. “Bioinformatics: Application in primer design”, 1st National Workshop and Colloquium on Pharmacogenetics. DK 6 & INFORMM. 1st April 2004.

27. “DNA sequence analysis” Workshop on Assembly PCR, Organized by National Biotechnology Directorate and School of Health Sciences, USM. 7 April 2004.

28. “Endnote” Intensive course on Biostatistics & Research Methodology for postgraduate students 27th June – 1st July 2004

29. “Advanced Bioinformatics” INFORMM Postgraduate Workshop Series 2: Research Output, DK6, Health Campus, USM, 14-16 March 2004,.


30. “Smart Referencing”, INFORMM Postgraduate Workshop Series 2: Research Output, , DK6, Health Campus, USM, 14-16 March 2004.

31. “PCR primer designing: A practical approach”, PCR Workshop, Department of Medical Microbiology and Parasitology, School of Medical Sciences, Health Campus, USM, 27-29 June 2004.

32. “Introduction to Bioinformatics” at INFORMM postgraduate workshop, Series (1): Introduction to R & D, Health Campus, USM, 6-8th December 2003

33. “Use of Patent search in research design” at INFORMM postgraduate workshop, Series (1): Introduction to R & D, Health Campus, USM, 6-8th December 2003

34. Bibliographic software and other tools for manuscript writing: An Overview, Workshop on producing quality thesis and Dissertations: Training the Trainers, Permai Park Inn, Kuala Terengganu, 16-18-Jan-2003.

35. Introduction to Reference manager: A Bibliographic software, , DK2, PPSP, 22nd February 2003

36. Introduction to Endnote bibliographic software, 26th June 2003, DK8, PPSP

37. Polymerase chain reaction and its application at Workshop on : Restriction fragment length polymorphism (RFLP) of “Mycobacterium tuberculosis” PPSK, Health campus, USM 09th June 2003

38. “Blue Print of Life” at Kursus Pemantapan Bioteknologi dalam pengajaran dan pembelajaran kepada guru-guru Biologi Negerri Kelantan, DK6, Health campus, USM, 2nd July 03

39. VNTI Bioinformatics software presentation, Micro conference room, PPSP, Health campus, USM, 24th May 2003

40. Introduction to Endnote Bibliographic software, Library, Health campus, USM, 17th August 2003

41. EZDNA Amp and Immunochromatograpy at Workshop on Current Progress & Future strategies for NBD Topdown - 3rd meeting, Health Campus, USM, Kelantan, 14 -15 Oct, 2003

11. PATENT APPLICATION

1. Ravichandran M and Girish Kumar Chandrasekharan. A System for Remotely Detecting the Presence of Aquatically Breeding Insects. Malaysian Patent Application, PI 2015701395 on 29 April 2015.

2. Chan Yean Yean ,Chua Ang Lim, Lalitha Pattabiraman, Manickam Ravichandran, Lim Boon Huat. Lateral flow device and method of detection of nucleic acid sequence. Malaysian Patent Application, PI 2010700012 filed on 8.3.2010

3. Chan Y. Y., M. Ravichandran, P. Lalitha, K. Balqis, Chua A. L. Enzyme-based electrochemical Geno-chromatography DNA biosensor and methods thereof. Malaysian patent filed on 12.03.2009 with the number PI 20090999

4. Manickam Ravichandran, Lalitha Pattabiraman, Lee Su Yin and Lim Kun Lee. Method and formulation of ambient temperature stable for nucleic acid amplification reagents. Malaysian patent filed on 31.03.2005 with the number PI20051471


5. Asma Ismail, Ong Kok Hai, Ravichandran M, Zainoodin S. A. Kader. DNA sequence encoding the specific antigen of Salmonella typhi. 28.2.2000, Malaysian Patent application number: PI 2000765 (filed in 23 countries)

6. Manickam Ravichandran , Syed Atif Ali , Nur Haslindawaty Abdul Rashid, Lalitha Pattabiraman, Zainul Fadziruddin Zainuddin. Vibrio cholerae strains VCUSM1 and VCUSM4 method of making same, and vaccine derivatives thereof. European patent EP1650315

7. Manickam Ravichandran , Syed Atif Ali , Nur Haslindawaty Abdul Rashid, Lalitha Pattabiraman, Zainul Fadziruddin Zainuddin. Vibrio cholerae strains VCUSM1 and VCUSM4 method of making same, and vaccine derivatives thereof. US Patent number (granted)- US 7838016

8. Manickam Ravichandran , Syed Atif Ali , Nur Haslindawaty Abdul Rashid, Lalitha Pattabiraman, Zainul Fadziruddin Zainuddin. Vibrio cholerae strains VCUSM1 and VCUSM4 method of making same, and vaccine derivatives thereof. Malaysian patent granted number MY-142562A .

9. Lalitha P, Ravichandran M, Asma Ismail, Zainuddin Z F. Oligonucleotides used for detecting Vibrio chlolerae and method of detecting therewith. 2002. Malaysian granted patent number MY-133325-A.

12. CONSULTANCY

1. Company: Malaysian Bio-Diagnostics Research Sdn Bhd. Project: Strategies for cloning and purification of specific protein for S typhi. Duration: March - August 1999 to February 2000 2. Lead consultant for Kedah Biotechnology Roadmap, Kedah State government, Malaysia 13. MAJOR COMMERCIAL ACHIEVEMENTS

1. EZTB Amp kit has been commercialized through Malaysian Bio-Diagnostics Research

Sdn Bhd, Malaysia.2006.

2. Typhi Rapid kit has been commercialized through Malaysian Bio-Diagnostics

Research Sdn Bhd, Malaysia.2006.

3. EZDNA Amp kit has been commercialized through Malaysian Bio-Diagnostics

Research Sdn Bhd, Malaysia.2005.

4. Spin-off/joint venture Companies resulting from commercialisation of IPR – Diagnostic

Innovations Sdn BhD, 2011

14. PROFESSIONAL SERVICES

14.1 Expert panel member and Examiner

1. Bioinformatics representative: appointed as Representative for Bioinformatics

activity for “Medical Biotechnology Cooperative centre” MBCC, Malaysia

2. Panel member for Fundamental Research Grant Scheme (FRGS) grant evaluation,

Sector Health.

3. Expert panel member for R,D&C grants: Sciencefund, Technofund, Community

Innovation Fund (CIF) and Enterprise Innovation Fund (EIF), Ministry of Science

Technology and Innovation (MOSTI), Malaysia 2010-2012.


4. Panel member of Pharmaceutical Control Bureau, Ministry of Health

5. Examiner for National Science Fellowship (NSF), MOSTI, Putrajaya, 26 September,

2006

6. ASM Working Committee member “Strengthening R&D&C Funding” for the MOSTI

Strategic and Action Plan (2009-2020), Date : Friday, 6th March 2009, Academy of

Sciences Malaysia, Kuala Lumpur

7. Cluster Working Group (CWG) Committee member on Human Capital Development,

Malaysian Biotechnology Corporation. 25 March 2010 to Present

8. Committee member on „TOP RESEARCH SCIENTISTS MALAYSIA‟ Academy of

Sciences Malaysia (ASM), Kuala Lumpur

9. Chairman of AIMST University Animal and Human ethics committee (AUHAEC)

since 25 January 2011- 23 August 2013.

10. Chairman of AIMST University Research Review Board July 2010.

11. Expert panel member: Sciencefund, Technofund, Community Innovation Fund (CIF)

and Enterprise Innovation Fund (EIF), 2013-2015, MOSTI Malaysia.

12. Promotion external assessor for Associate Professor (DS54) promotion, Universiti Sains Malaysia in January & April 2014.

15. MANUSCRIPT REVIEWER 1. BMC Microbiology

2. BMC Genomics

3. BMC Research Notes

4. Comparative and Functional Genomics

5. Malaysian Journal of Medical Sciences

6. Malaysian Journal of Pharmaceutical Sciences

7. Bioinformation

8. Malaysian Journal of Microbiology

9. Tropical Biomedicine

10. Journal of Bioscience

16. COMMITTEES/MEMBERS

1. Scientific committee: 2nd National Conference on Infectious Diseases, 14-15

February 2007, Grand River View hotel, Kota Bharu.

2. Scientific committee: The first international conference on the medicinal use of honey.

26-28 August 2006. Health Campus, USM

3. Scientific committee: First National Conference on Medical Laboratory Sciences, 7-9

November 2006, Grand River View hotel, Kota Bharu.

4. Scientific committee: First National Conference on Infectious Diseases, 28-29

September 2005, Health Campus, USM

5. Judge for 1st Asean conference on Medical Sciences, 18-21 May 2001, Kota Bharu,

Malaysia

6. Research Committee, School of Medical Sciences, USM 2007 to 2008.


17 . PROFESSIONAL MEMBERSHIP

1. Academy of Science Malaysia (ASM), Associate member (April 2013 – March 2015)

2. American Society for Microbiology (ASM) Member, since 2002

3. American Association for the advancement of sciences (AAAS) Member, since 2003

4. International Society for Infectious Diseases, Member since 2008

5. Malaysian Society of Parasitology and Tropical Medicine, Member, since 1998

6. Malaysian Society for Molecular Biology and Biotechnology, Member since 2002

7. Malaysian Microbiology Society, Member since 2003

curriculum vitae prof. manickam … no 6-cv of prof ravi.pdf · a. b.sc biotechnology program ......

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