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CURRICULUM VITAE

KANWAL ‘KEN’ NISCHAL

Professor of Ophthalmology University of Pittsburgh Medical Center

Director of Pediatric Ophthalmology, Strabismus and Adult Motility

Children’s Hospital of Pittsburgh UMPC Eye Center

Honorary Consultant Ophthalmic Surgeon

Great Ormond Street Hospital for Children

Honorary Member

Developmental Biology Unit, UCL Institute of Child Health

Visual Professor

Lypei, Hyderabad, India

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PERSONAL DETAILS

Name KANWAL ‘KEN’ NISCHAL

Date of birth 20th December 1964 E-mail Nischalkk@upmc.edu Nationality BRITISH

Status Married

G.M.C. 3298691

M.D.U. 23056OG

DEA: FN2948923 General Education Slough Grammar School, Slough, Berkshire.

Medical School King's College Hospital Medical School University of London 1983-1988

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Nov 2011- Present PROFESSOR OF OPHTHALMOLOGY University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA Cheif, PEDIATRIC OPHTHALMOLOGY UPMC Eye Center - Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA Jan 1999 – Oct 2011 CONSULTANT OPHTHALMIC SURGEON Great Ormond Street Hospital for Children, London HONORARY SENIOR LECTURER Institute of Child Health HONORARY CONSULTANT OPHTHALMIC SURGEON Moorfields Eye Hospital, London 2007 – Present VISITING PROFESSOR LV Prasad Eye Institute, Hyderabad, India Jan 1998 –Jan 1999 CLINICAL FELLOW IN PAEDIATRIC OPHTHALMOLOGY The Hospital for Sick Children, Toronto July 95 – Jan 98 SENIOR REGISTRAR ROTATION, Ophthalmology Oxford Eye Hospital, Oxford and Prince Charles Eye Unit, Windsor Feb. 1994 - June 1995 REGISTRAR ROTATION, Ophthalmology Birmingham and Midlands Rotation, Birmingham Feb. 1992 - Jan.1994 SENIOR HOUSE OFFICER, Ophthalmology Prince Charles’ Eye Unit, Windsor Feb. 1991- Jan. 1992 SENIOR HOUSE OFFICER, Ophthalmology King’s College Hospital, London

Aug. 1990 - Jan. 1991 NEUROSURGERY LECTURER The Royal London Hospital, London

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Feb. 1990 - June 1990 ANATOMY DEMONSTRATOR Guy’s Hospital, London Aug. 1989 - Feb 1990 Casualty Officer St. Thomas’ Hospital, London Feb. 1989 - July 1989 House Physician, King's College and Dulwich Hospitals Aug. 1988 -Jan. 1989 House Surgeon St. Helier's Hospital, Carshalton CURRENT POSITION Director of Pediatric Ophthalmology, Strabismus and Adult Motility Past Responsibilities Head of Clinical and Academic Department of Ophthalmology

We have four fellows and one junior resident. Two fellows work with me at any one given time. One of these fellows is split between GOSH and King’s College Hospital, London.

Fellowship Director And Unit Training Director

Royal College of Ophthalmologists Tutor

The National Specialist Commissioning Advisory Group (NSCAG) aims to help patients by improving access to uncommon services, whilst at the same time seeking to sustain high levels of expertise by preventing proliferation to too many centres.

NSCAG Ophthalmologist

In addition to my normal workload, I am funded by NSCAG to deliver Ophthalmic care and service strategies to all patients at Great Ormond St Hospital for Children with: 1 Craniofacial Anomalies 2 Epidermolysis Bullosa Service Developments Since commencing my post in January 1999 I have introduced eleven main service developments 1 Penetrating and lamellar keratoplasty service for appropriate neonates , infants

and children 2 Ultrasound service : high frequency ultrasound, posterior segment ultrasound

and biometry for intraocular implant calculations 3 Management protocol for periocular haemangiomas

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4 Management protocol for Visual function surveillance in Craniosynostoses As a result of demonstrating to the National Specialist Commissioning Advisory Group (NSCAG) the effect of this new management protocol, we received a centrally funded grant of 47000 sterling pounds on a recurrent annual basis in June 2002.

5 Botulinum Toxin for paediatric strabismus 6 Ophthalmic Surveillance for children with Epidermolysis Bullosa As a result

of demonstrating improved quality of life with decreased corneal erosions NSCAG provided 2 Consultant Sessions of funding for this service starting April 2004

7 Eyemovement service: in 2009 I recruited a doctor to set this service up.IN 2010 clinics were set up to provide this service

8 In 2009 a clinical nurse specialist post was developed to allow nurse led clerking of admissions and hence reduced dependency on inexperienced junior doctors

9 In 2009 A joint paediaric neuroophthalmology post was created between GOSH and Whipps Cross hospitals and a candidate successfully appointed

10 In 2010 a second anterior segment surgeon post was created and a successful candidate appointed full time at Great Ormond Street Hospital for Children

11 In 2009 the ‘low vision aid service’ was developed with Lynne Speedwell and a candidate successfully appointed to run this service

Although my two colleagues did treat paediatric glaucoma before my arrival, this has been part of my responsibilities since my arrival. I have introduced releasable sutures for paediatric trabeculectomy, Ahmed tube implant (which I learned about while fellow at HSC, Toronto) and high frequency ultrasound guidance for cycloablation. I have gained 7 Clinical Excellence Awards because of my contribution to the National Health Service both at Local And National Levels RESEARCH INTERESTS 1 Craniosynostoses

• Extraocular muscles o Structure o Genotype-phenotype correlation o Strabismus

Evaluation Treatment

• Visual Loss o Amblyopia o Optic neuropathy

Causes Treatment

2 Ultrasound

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• Normal Ultrasound o Linear

Use in biometry and lens diameter estimation

o Doppler Vascular anomalies

• High Frequency Ultrasound o Diagnosis in congenital corneal opacification o Therapeutic use for Cyclodiode laser o Corneal thickness measurement

3 Paediatric Anterior Segment • Cataract

o with and without implantation • Keratoplasty

o Penetrating Congenital corneal developmental

opacification Acquired

o Deep Anterior Lamellar Keratoplasty • Amniotic Membrane Transplant

o Epidermolysis bullosa • Glaucoma

o Goniotomy o Trabeculotomy with Trabeculectomy (MMC and

releasable sutures) o UBM guided Cyclodiode laser o Ahmed Tube

RESEARCH GRANTS AND FUNDS 1 JS Rahi, IM Russell-Eggitt, KK Nischal, DSI Taylor, CS Peckham Outcomes of congenital and infantile cataract in the United Kingdom and their predictors – national study in collaboration with the British Congenital Cataract Interest Group Guide Dogs for the Blind Association Project Grant. 2001 £94,552 2 KK Nischal Ocular aspects of Craniofacial Disorders National Specialist Commissioning Advisory Group (NSCAG) 2002 Recurring annual funding £64,000 3 KK Nischal

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National Specialist Commissioning Advisory Group (NSCAG) 2004 Recurrent annual funding £27,000 4 KK Nischal, A Martinez, J Mellerio Ocular phenotype in Epidermolysis Bullosa Dystrophic Epidermolysis Bullosa Research Association 2005 £47,000 5 KK Nischal, C Tuleu, O Rabiu, R Sekhri, W Van’t Hoff £103,000 Development of cysteamine gel for patients with cystinosis Cystinosis Research Network USA 2006 AWARDS, PRIZES

1. 1995 Royal Eye Hospital, London Poster Prize at the Annual Congress of the Royal College of Ophthalmologists

2. 1997 Keeler Scholarship 1997- 1998

3. 2005 World Cornea Congress V. April 14-15 th 2005, Washington DC.

Honourable Mention for Poster: Amniotic Membrane Transplant in Children with Symblepharon and Massive Corneal Pannus

PROFESSIONAL BODIES

• British Medical Association • Royal Society of Medicine • Foundation of Science and Technology • AAO ( American Academy of Ophthalmology) • AAPOS ( American Assoc. of Pediatric Ophthalmology and Strabismus) • EPOS ( European Paediatric Ophthalmology Society)

PUBLICATIONS PEER REVIEWED PAPERS

I K.K. Nischal, P. Chumas, Sparrow O. Prolonged survival after atlanto-occipital dislocation: two case reports and review.

British Journal of Neurosurgery 1993; 7(6): 677-682 2a K.K. Nischal, W. Aclimandos Bilateral symmetrical branch retinal artery occlusion Journal of the Royal Society of Medicine. 88(7): 416P-417P, 1995

Jul. (presented as a poster at RSM Registrar's meeting 1993)

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2b Author's Reply to letter Journal of the Royal Society of Medicine 1995; 88 3 K.K. Nischal, J.N. James, J.J. Kanski Proptosis precipitated by retinal detachment repair in a patient with occult Pituitary tumour. EYE. 9 (5): 647-9, 1995

(Presented as a poster at Annual Congress of the Royal College of Ophthalmologists 1994) 4 K.K. Nischal, J.N. James, J. McAllister

Use of dynamic ultrasound B-scan to detect retinal tears in spontaneous vitreous haemorrhage. EYE 1995 (4); 9: 502-506

(Presentation in Retinal Detachment Symposium at Annual Congress of the Royal College of Ophthalmologists 1994)

5 S, Beatty, K.K. Nischal, T. Gillow, P. McDonnell DIY Enthusiasts; a new target group for safety awareness.

Journal of Health and Safety - November 1995

6 S. Beatty, K. K. Nischal, H. Jones, E.M. Eagling The effect of applanation tonometry on mean corneal curvature

Journal of Cataract and Refractive Surgery. 22(7): 970-1, 1996 Sep.

7 M. Hingorani, K.K. Nischal, A. Davies, W. Aclimandos

Prostatic orbital metastases and the role of the ophthalmologist British Journal of Urology. 78(4): 654-7, 1996 Oct

8 K.K. Nischal, M. Hingorani, A. Vivian, A. Baker, G. Mieli-Vergani,

A.C.Bird and W.A. Aclimandos. Optic Nerve Head Drusen- a New Sign in Alagille's Syndrome. Ophthalmology. 104(1): 79-85, 1997

9 A. Assi, K.K. Nischal, J. Uddin, M. Thyveetil Giant cell arteritis masquerading as squamous cell carcinoma British Journal of Rheumatology. 36(9): 1023-5, 1997 Sep.

10 D. Byles, K. K. Nischal, and H. Cheng Ectopia pupillae et lentis - a hypothesis revisited.

Ophthalmology. July 1998; 105(7): 1331-6

11 M. Hingorani, K.K. Nischal, A. Vivian, A. Baker, G. Mieli-Vergani, A.C. Bird and W.A. Aclimandos. Ocular Abnormalities in Alagille’s Syndrome. Ophthalmology. Feb 1999; 106(2): 330-7

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12 L. MacKeen, K.K.Nischal, W.C. Lam, A. V. Levin. High-frequency ultrasonography findings in persistent hyperplastic primary vitreous.

J AAPOS. 2000 Aug; 4(4): 217-24.

13 N. Mungan, K.K.Nischal, L. MacKeen, E Heon Ultrasound biomicroscopy of the eye in cystinosis Arch Ophthalmol. 2000 Oct; 118(10): 1329-33.

14 Karia N, Doran J, Watson SL, Nischal K Surgically induced necrotizing scleritis in a patient with ankylosing

spondylitis. J Cataract Refract Surg. 1999 Apr; 25(4): 597-600

15 Browning AC, Reck AC, Chisholm IH, Nischal KK. Acute angle closure glaucoma presenting in a young patient after administration of paroxetine.

Eye. 2000 Jun; 14 (3a): 406-8.

16 Cassidy L, Rahi J, Nischal K, Russell-Eggitt I, Taylor D. Outcome of lens aspiration and intraocular lens implantation in children aged 5 years and under. Br J Ophthalmol. 2001 May; 85(5): 540-2

17 Taylor D. Wright KW. Amaya L. Cassidy L. Nischal K. Russell-Eggitt I.

Should `we aggressively treat unilateral congenital cataracts?: View 1. British Journal of Ophthalmology. Vol. 85(9) (pp. 1120-1125), 2001.

18 Clinicopathologic correlation of congenital corneal opacification using

ultrasound biomicroscopy. KK Nischal, J Naor, V. Jay, LD MacKeen, DS Rootman. Br J Ophthalmol 2002;86: 62-69

19 Westall CA. Dhaliwal HS. Panton CM. Sigesmund D. Levin AV. Nischal

KK. Heon E. Values of electroretinogram responses according to axial length. Documenta Ophthalmologica. Vol. 102(2) (pp. 115-130), 2001

20 L Amaya, D Taylor, I Russell-Eggitt, KK Nischal. Phacoaspiration not

phacoemulsification for paediatric cataract extraction. ( Letter ). J Cat Refr Surgery 2001:27(10) :

21 Kushner BJ, Stevens JL, Nischal KK, Karr DJ, Davis JS, Christiansen SP,

Brown SM. Grand Rounds #65: a case of a left hypertropia which decreases markedly in both upgaze and downgaze. Binocul Vis Strabismus Q. 2002 Spring;17(1):36-42

22 Nischal KK. Two-incision push-pull capsulorhexis for pediatric cataract

surgery. J Cataract Refract Surg. 2002 Apr; 28(4):593-5

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23 Nischal KK. Ocular Aspects of Craniofacial Disorders. The John Pratt Johnson Lecture 2001. American Orthoptic Journal; 52: 58-68

24 Ong T, Chia A, Nischal KK. Efficacy of Latanoprost in Portwine Stain

Related Paediatric Glaucoma. Br J Ophthalmol. 2003 Sep;87(9):1091-3.

25 Khan S, Nischal KK, Dean F, Hayward R, Walker J. Visual Morbidity in

Craniosymostoses – review of 141 cases. Br J Ophthalmol. 2003 Aug;87(8):999-1003.

26 Morris S, Geh V, Ahmed, Nischal KK. Metabolic Acidosis and Topical Ddorzolamide 2%. Br J Ophthalmol. 2003 Aug;87(8):1052-3

27 Rattigan S, Nischal KK. Foster Modification of Knapp Procedure for Anomalous Superior Rectus Muscles in Craniosynostoses.

J AAPOS. 2003 Aug;7(4):279-82

28 Liasis A, Dorothy Thompson, Hayward R, Nischal KK. Sustained raised intracranial pressure implicated only by pattern reversal visual evoked potentials after cranial vault expansion surgery. Pediatr Neurosurg. 2003 Aug;39(2):75-80.

29 Luis Amaya MD, David Taylor FRCOph Isabelle Russell-Eggitt FRCOph, Ken K. Nischal FRCOph and Dora Lengyel MD . The Morphology and Natural History of Childhood Cataracts. Survey of Ophthalmology Volume 48, Issue 2 , March-April 2003, Pages 125-144

30 Mungan NK, Wilson TW, Nischal KK, Koren G, Levin AV. Hypotension

and bradycardia in infants after the use of topical brimonidine and beta- blockers. J AAPOS. 2003 Feb;7(1):69-70

31 Speedwell L., Stanton F., Nischal KK. Informing parents of visually

impaired children:who should do it and when? Child: Care,Health and Development.29,3,219-224.

32 al-Khaier A, Nischal KK. The eye in metabolic disease.

Hosp Med. 2003 Oct;64(10):609-12.

33 Nischal KK. Pediatric Keratoplasty. Techniques in Ophthalmol. 2003. 1(2):119-126

34 Vishwanath M, Nischal KK, Carr L. Juvenile Myasthenia Gravis

Mimicking Recurrent VI Nerve Palsy of Childhood. Archives of Diseases in Childhood 2004. 89(1): 90

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35 Bowman RJ, Cope J, Nischal KK. Ocular and systemic side effects of

brimonidine 0.2% eye drops (Alphagan((R))) in children. Eye. 2004 Jan;18(1):24-6.

36 Indelman M, Hamel CP, Bergman R, Nischal KK, Thompson D, Surget MO, Ramon M, Ganthos H, Miller B, Richard G, Lurie R, Leibu R, Russell-Eggitt I, Sprecher E. Phenotypic diversity and mutation spectrum

in hypotrichosis with juvenile macular dystrophy. J Invest Dermatol. 2003 Nov;121(5):1217-20.

37 Clement R., Nischal KK. Simulation of oculomotility in Craniosynostosis

patients. Strabismus. 2003 Dec; 11(4): 239-42.

38 Bowman RJ, Patel K, Harper J, Nischal KK. An Ultrasound Based Classification of Peri-ocular Haemangiomas. Br J Ophthalmol. 2004 Nov;88(11):1419-21.

39 Crow YJ, Massey RF, Innes JR, Pairaudeau PW, Rowland Hill CA,

Woods CG, Ali M, Livingston JH, Lebon P, Nischall K, McEntagart M, Hindocha N, Winter RM.Congenital glaucoma and brain stem atrophy as features of Aicardi-Goutières syndrome. Am J Med Genet. 2004 Sep 1;129A(3):303-7.

40 Ioannidis A, Davies G, Veys P, Nischal KK. Chickenpox Keratitis in a

Child with Severe Combined Immunodeficiency; A Case of Immune Recovery Disease. Br J Ophthalmol 2004; 88: 1601-1602

41 Ioannidis A, Speedwell L, Nischal KK. Keratoconus in a child with

chronic rubbing. Am J Ophthalmol. Vol 139/2 pp 356-357 42 Pinches E, Thompson D, Noordeen H, Nischal KK. Cranial Nerve Injury

Following Halo Traction in Children. J AAPOS. 2004 Dec;8(6):580-5.

43 Vishwanath MR, Taylor DSI, Thompson DA, Nischal KK. Achiasmia – a Review. Brainchild 2004.5(1):10-13

44 Hill VA, Nischal KK, Collin JR, Harper JI. An unusual ectodermal

dysplasia with unique eye defects. Br J Dermatol. 2005 Feb;152(2):365-7.

45 Liasis A.,Nischal K.K.,Leighton S.,Yap S.,Hayward R., Dunaway, D. Adenoid-tonsillectomy to treat visual dysfunction in a child with craniosynostosis" Pediatric Neurosurgery, Vol. 41, No. 4, pp 197 - 200, 2005

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46 Ioannidis AS, Liasis A, Syed S, Harper J, Nischal KK.The value of visual evoked potentials in the evaluation of periorbital hemangiomas. Am J Ophthalmol. 2005 Aug;140(2):314-6.

47 Dansingani K, Al-Khaier A, Russell-Eggitt IM, Nischal KK. Intrastromal

Corneal Bleb; An Unusual Complication following Trabeculectomy for Congenital Glaucoma. Management of Intracorneal Bleb After Trabeculectomy for Congenital Glaucoma. Cornea. 2005 May;24(4):486-488.

PEER REVIEWED PAPERS CONT’D

48 DeSilva J, Nischal KK, Packard RB. Preoperative assessment of secondary intraocular lens implantation for aphakia: A comparison of 2 techniques J Cat Refr Surg 2005 31(7):1351-1356

49 Sami DA, Saunders D, Thompson DA, Russell-Eggitt IM, Nischal KK,

Jeffrey G, Dattani M, Clement RA, Liasis A, Taylor DS.The achiasmia spectrum: congenitally reduced chiasmal decussation. Br J Ophthalmol. 2005 Oct;89(10):1311-7

50 Ioannidis A, Liasis A, Sheldrick J, Snead M, Nischal KK. Lamellar

macular hole as the presenting feature in a child with Coats' disease. J Pediatr Ophthalmol Strabismus. 2005 Nov-Dec;42(6):378-9.

51 Khan SH, Britto JA, Evans RD, Nischal KK.Expression of FGFR-2 and

FGFR-3 in the normal human fetal orbit. Br J Ophthalmol. 2005 Dec;89(12):1643-5.

52 Cleary G, Nischal KK, Jones CA.Penetrating orbital trauma by stiletto

causing complex cranial neuropathies. Emerg Med J. 2006 Apr;23(4):e28.

53 Thompson DA, Liasis A, Hardy S, Hagan R, Hayward RD, Evans RD,

Nischal KK. Prevalence of Abnormal Pattern Reversal Visual Evoked Potentials in Craniosynostosis. Plast Reconstr Surg. 2006 Jul;118(1):184-192.

54 Hamada S, Low S, Walters BC, Nischal KK. Five-year experience of the 2-incision push-pull technique for anterior and posterior capsulorrhexis in pediatric cataract surgery. Ophthalmology. 2006 Aug;113(8):1309-14.

55 Alki Liasis; Ken K. Nischal; Bronwen Walters; Dorothy Thompson; Sharon Hardy; Anthony Towell; David Dunaway; Barry Jones; Robert Evans; Richard Hayward. Monitoring Visual Function in Children With

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Syndromic Craniosynostosis: A Comparison of 3 Methods Arch Ophthalmol. 2006;124:1119-1126.

56 Raina Goyal, FRCS; Sophie M. Jones, MRCSEd, MRCOphth; Marcela Espinosa, FRCS; Vanessa Green, RGN; Ken K. Nischal, FRCOphth. Amniotic Membrane Transplantation in Children With Symblepharon and Massive Pannus Arch Ophthalmol. 2006;124:1435-1440

57 Mezer E, Nischal KK, Nahjawan N, Mackeen LD, Buncic JR. Hemifacial spasm as the initial manifestation of childhood cerebellar astrocytoma.. J AAPOS. 2006 Oct;10(5):489-90. PEER REVIEWED PAPERS CONT’D 58 Strauss RM, Bate J, Nischal KK, Clayton T, Gooi J, Darling JC, Newton- Bishop JA.A child with laryngo-onychocutaneous syndrome partially responsive to treatment with thalidomide. Br J Dermatol. 2006 Dec;155(6):1283-1286. 59 Moore W, Nischal KK .Pharmacologic management of glaucoma in childhood. Paediatr Drugs. 2007;9(2):71-9. 60 Geh JL, Geh VS, Jemec B, Liasis A, Harper J, Nischal KK, Dunaway D. Surgical treatment of periocular hemangiomas: a single-center experience. Plast Reconstr Surg. 2007 Apr 15;119(5):1553-62. 61 Nischal KK. Who needs a reversibly adjustable intraocular lens? Arch Ophthalmol. 2007 Jul;125(7):961-2 62 Nischal K.Is non-syndromic single suture craniosynostosis purely an aesthetic problem? Dev Med Child Neurol. 2007 Jul;49(8):565. 63 Nischal KK Congenital corneal opacities - a surgical approach to nomenclature and classification.Eye. 2007 Oct;21(10):1326-37. 64 Rice G, Patrick T, Parmar R, Taylor CF, Aeby A, Aicardi J, Artuch R,

Montalto SA, Bacino CA, Barroso B, Baxter P, Benko WS, Bergmann C, Bertini E, Biancheri R, Blair EM,

Blau N, Bonthron DT, Briggs T, Brueton LA, Brunner HG, Burke CJ, Carr IM, Carvalho DR, Chandler KE, Christen HJ, Corry PC, Cowan FM,

Cox H, D'Arrigo S, Dean J, De Laet C, De Praeter C, Dery C, Ferrie CD, Flintoff K, Frints SG, Garcia-

Cazorla A, Gener B, Goizet C, Goutieres F, Green AJ, Guet A, Hamel BC, Hayward BE, Heiberg A,

Hennekam RC, Husson M, Jackson AP, Jayatunga R, Jiang YH, Kant SG, Kao A, King MD, Kingston HM,

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Klepper J, van der Knaap MS, Kornberg AJ, Kotzot D, Kratzer W, Lacombe D, Lagae L, Landrieu PG, Lanzi

G, Leitch A, Lim MJ, Livingston JH, Lourenco CM, Lyall EG, Lynch SA, Lyons MJ, Marom D,

McClure JP, McWilliam R, Melancon SB, Mewasingh LD, Moutard ML, Nischal KK, Ostergaard JR, Prendiville J, Rasmussen M, Rogers RC, Roland D, Rosser EM, Rostasy K, Roubertie A, Sanchis A,

Schiffmann R, Scholl-Burgi S, Seal S, Shalev SA, Corcoles CS, Sinha GP, Soler D, Spiegel R, Stephenson JB,

Tacke U, Tan TY, Till M, Tolmie JL, Tomlin P, Vagnarelli F, Valente EM, Van Coster RN, Van der Aa N,

PEER REVIEWED PAPERS CONT’D

Vanderver A, Vles JS, Voit T, Wassmer E, Weschke B, Whiteford ML, Willemsen MA, Zankl A, Zuberi SM, Orcesi S, Fazzi E, Lebon P, Crow YJ.Clinical and molecular phenotype of Aicardi-Goutieres syndrome.Am J Hum Genet. 2007 Oct;81(4):713-25. Epub 2007 Sep 4

65 Jones SM, Weinstein JM, Cumberland P, Klein N, Nischal KK.

Visual outcome and corneal changes in children with chronic blepharokeratoconjunctivitis.Ophthalmology. 2007 Dec;114(12):2271-80.

66 Briggs TA, Abdel-Salam GM, Balicki M, Baxter P, Bertini E, Bishop N,

Browne BH, Chitayat D, Chong WK, Eid MM, Halliday W, Hughes I, Klusmann-Koy A, Kurian M, Nischal KK, Rice GI, Stephenson JB, Surtees R, Talbot JF, Tehrani NN, Tolmie JL, Toomes C, van der Knaap MS, Crow YJ.Cerebroretinal microangiopathy with calcifications and cysts (CRMCC).Am J Med Genet A. 2008 Jan 15;146A(2):182-90.

67 Low S, Hamada S, Nischal KK.Antimetabolite and releasable suture

augmented filtration surgery in refractory pediatric glaucomas. J AAPOS. 2008 Apr;12(2):166-72.

68 Witherow H, Dunaway D, Evans R, Nischal KK, Shipster C, Pereira V,

Hearst D, White M, Jones BM, Hayward R.Functional outcomes in monobloc advancement by distraction using the rigid external distractor device.Plast Reconstr Surg. 2008 Apr;121(4):1311-22.

69 Gore DM, Thyagarajan S, Liasis A, Nischal KK.Functioning avascular

retinae-a report of two siblings.Eye (Lond). 2009 Feb;23(2):491-3

70 Nischal KK. Full or partial hypermetropic correction for accommodative esotropia: does it matter?Br J Ophthalmol. 2008 Oct;92(10):1303

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71 Wong IB, Sukthankar VD, Cortina-Borja M, Nischal KK. Incidence of early-onset glaucoma after infant cataract extraction with and without intraocular lens implantation.Br J Ophthalmol. 2009 Sep;93(9):1200-3.

72 Smith KA, Nischal KK.Consecutive exotropia: does one size fit all?

Br J Ophthalmol. 2009 Jun;93(6):706-7 PEER REVIEWED PAPERS CONT’D

73 Solebo AL, Russell-Eggitt I, Nischal KK, Moore AT, Cumberland P, Rahi JS; British Isles Congenital Cataract Interest Group. Cataract surgery and primary intraocular lens implantation in children < or = 2 years old in the UK and Ireland: finding of national surveys. Br J Ophthalmol. 2009 Nov;93(11):1495-8. Epub 2009 Jun 16.

74 Nischal KK Amblyopia: what does the future hold? . Br J Ophthalmol. 2009 Oct;93(10):1271-2

75 Nischal KK, Solebo L, Russell-Eggitt I. Paediatric IOL implantation and postoperative refractive state: what role do study methodology and surgical technique play?Br J Ophthalmol. 2010 May;94(5):529-31.

76 Wong IB, Nischal KK.Managing a child with an external ocular disease.

J AAPOS. 2010 Feb;14(1):68-77.

77 Aragon-Martin JA, Ahnood D, Charteris DG, Saggar A, Nischal KK, Comeglio P, Chandra A, Child AH, Arno G. Role of ADAMTSL4 mutations in FBN1 mutation-negative ectopia lentis patients. Hum Mutat. 2010 Jun 17.

78 Absoud M, Cummins C, Desai N, Gika A, McSweeney N, Munot P,

Hemingway C, Lim M, Nischal KK, Wassmer E. Childhood optic neuritis clinical features and outcome. Arch Dis Child. 2010 Jun 16.

79 Nischal KK. Maternal drug abuse and ocular morbidity: more than meets

the eye? Br J Ophthalmol. 2010 Jun;94(6):671. NON PEER-REVIEWED PAPERS

1 Uveitis in Juvenile Rheumatoid Arthritis. Canadian J Rheumatology Spring 1999

2. Goniotomy. MORinformation- Family Association of Children with

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Congenital Glaucoma ( Canada) 1999 3 Ultrasound in the Child’s Eye. BMUS August 2001

BOOKS 1 J.J.Kanski, K.K. Nischal.

PICTURE TESTS IN OPHTHALMOLOGY Churchill Livingstone 1994 2 J.J. Kanski, K.K. Nischal

CLINICAL OPHTHALMOLOGY - A TEST YOURSELF ATLAS Butterworth-Heinemann 1995

3 J.J. Kanski, K.K.Nischal.

OPHTHALMOLOGY – SIGNS AND DIFFERENTIAL DIAGNOSIS Mosby 1998

CHAPTERS 1 K.K. Nischal, J. S. Elston

Ophthalmic Care : Advanced Trauma Care BMJ Publishing 1999 2 K.K.Nischal

Ultrasound of the Eye: Key Topics in Ophthalmology 2nd Ed. RH Taylor et al BIOS Publishing 2001

3 K.K. Nischal

Iris Abnormalities: Pediatric Ophthalmology and Strabismus 2nd Ed. Wright and Spiegel Ed. Springer Verlag Publishing 2002

4 K.K. Nischal

Corneal Abnormalities Pediatric Ophthalmology and Strabismus 2nd Ed. Wright and Spiegel Ed Springer Verlag Publishing 2002

5 K.K.Nischal

Developmental anomalies of the anterior segment and globe Pediatric Ophthalmology and Strabismus 2nd Ed. Wright and Spiegel Ed Springer Verlag Publishing 2002

6 K.K.Nischal

Paediatric Ophthalmology Great Ormond St Hospital Handbook of Pediatric Medicine

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7 KK Nischal Ocular Ultrasound Pediatric Ophthalmology and Strabismus 2004 Elsevier ; Eds. Taylor DSI and Hoyt C

8 KK Nischal , J Sowden Anterior Segment Developmental Anomalies Pediatric Ophthalmology and Strabismus 2004 Elsevier; Eds. Taylor DSI and Hoyt C

9 KK Nischal

Ocular Features of Craniosynostoses in The Clinical Management of Craniosynostosis. Clinics in Developmental Medicine (Mac Keith Press) 2004 Eds. Hayward R, Jones B, Dunaway D, Evans R

10 R Hayward, KK Nischal

Raised Intracranial Pressure in The Clinical Management of Craniosynostosis. Clinics in Developmental Medicine (Mac Keith Press) 2004 Eds. Hayward R, Jones B, Dunaway D, Evans R

11 Anthony J.Bron, Anthony Aldave, Saeed Akhtar, Helen S. Stewart Ken

K.Nischal (2007) Inherited Dystrophies and Developmental Anomalies of the Cornea; in Duane's Ophthalmology : edited by William Tasman MD; Edward A Jaeger MD; Source: Lippincott Williams & Wilkins (LWW) ISBN-13: 9780781768559

12 KK Nischal The Child’s Eye in ‘Paediatric Ultrasound; 2nd Ed. Rose DeBruyn How,Why and When’ Chruchill Livingstone,Elsevier 2010

13 BCSC American Academy of Ophthalmology : Section 6

Pediatric Ophthalmology and Strabismus Part Of Editorial team responsible for MAJOR revision 2009-2010

14 Part of AAO Committee to write COMPASS evaluation papers for

revalidation. 2008-9 15 KK Nischal

Pediatric Cataract Surgery in Ophthalmic Surgery, 4/e Edited by Spaeth, Danesh-Meyer and Kampik Benjamin, Damato, Goldberg, Hintschich, Kohnen, Lambert, Traverso Elsevier, in press

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INVITED SPEAKER PAPERS 1 Emmetropisation British Chapter of the American Academy of Optometrists, Oxford 1995 2 Extraocular movements in Craniofacial disorders Paediatric study day - Children's Hospital, Warsaw. Poland. March 1997 3 Prediction of post-op diplopia in the management of unilateral traumatic cataract. UKISCRS (United Kingdom and Ireland Society of Cataract and Refractive Surgeons) Chester 1997

4 Paediatric Glaucomas

Royal College of Ophthalmologists Seminar: The Secondary Glaucomas Sept 25th 1998

5 Ocular Features of Moebius Syndrome International Moebius Conference Toronto - August 1998 6 Uveitis in Children British Council Course for Paediatric Ophthalmologists. Sept. 21st 1998 7 Craniosynostoses and facial development

Genes and Development Royal Society of Medicine London March 1999

8 Paediatric Cataract Surgery

Leeds Symposium on Cataract Surgery November 1999

9 Ophthalmic Aspects of Craniofacial Disorders

Paediatric Ophthalmology and Strabismus Meeting London Jan 2000

10 Ocular Ultrasound

Polish Vitreoretinal Meeting Posnan Apr 1999

11 Assessment of Strabismus

Paediatric Ophthalmology Meeting Warsaw May 1999

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12 Nystagmus Oxford Motility Day Oxford Eye Hospital October 1999

13 Practical Paediatric Neurology

Institute of Child Health November 1999, 2000

14 Congenital Corneal Opacification

British Orthoptic Society Meeting November 1999

15 Difficult Paediatric Ophthalmology Problems

AAPOS Meeting, San Diego April 2000

16 Capillary Haemangiomas and Laser Treatment Institute of Child Health Nov 2000 ‘Management of periocular haemangiomas ‘

17 Ophthalmic Society of Pakistan and Lahore Ophthalmo

Joint Meeting Nov 2000. Visiting Professor ‘Diagnosis of Paediatric Glaucoma’ ‘Surgical Techniques in Paediatric Glaucoma ‘ ‘Surgical Aspects of Paediatric Cataract Management’

18 SouthEast London Regional Study Day

Nov 2000 King’s College Hospital, London Management of Periocular Haemangiomas

19 Cornelia de Lange Syndrome Convention

The Wirral June 2000 ‘Ophthalmic Aspects of CdLS ‘

20 Congenital Corneal Opacification

Nottingham University Regional Study Day April 2000

21 Surgical Aspects of Paediatric Glaucoma

North West Thames Regional Study Day December 2000

22 Cystinosis Foundation Birmingham June 2000‘Ophthalmic Aspects of Cystinosis ‘

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23 Strabismus in Craniofacial Disorders Royal Society of Medicine Strabismus Meeting 14th Dec 2000

24 Clinico-pathologic correlation of Congenital Corneal Opacification Bowman Club Liverpool 2001

25 Visual Problems in Deaf Children

Cochlear Implants Update for Professionals May 2001 Institute of child Health

26 John Pratt Johnson Lecture Ocular Aspects of Craniosynostoses The Canadian Orthoptic Society Canadian Ophthalmic Society Meeting Toronto 2001

27 Current Concepts – Management of Peri-ocular haemangioma Canadian Ophthalmic Society Meeting

Toronto 2001

28 Management of Paediatric and Neonatal Lens Implantation Canadian Association of Paediatric Ophthalmologists Canadian Ophthalmic Society Meeting Toronto 2001

29 Emmetropisation The Canadian Orthoptic Society

Canadian Ophthalmic Society Meeting Toronto 2001

30 Cataract Through The Ages

Canadian Ophthalmic Personnel Course Canadian Ophthalmic Society Meeting Toronto 2001

31 The Eye in Epidermolysis Bullosa

Scandinavian EB Meeting, Oslo Norway April 2002

32 Paediatric Keratoplasty

Manchester Eye Hospital May 2002

33 Surgical Techniques in Paediatric Cataract Surgery Oxford Congress July 2002

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34 When to do what for Periocular Haemangiomas Children’s Eye Group meeting ICH, London July 2002

35 Visiting Professor Pediatric Ophthalmology Day St Justine Hospital, Montreal Nov 2002

36 Advances in Paediatric Anterior Segment Surgery Catalunya Ophthalmological Society Meeting Barcelona Nov 2002

37 Pediatric Cataract Surgery Cardiff Eye Unit June 2003

38 Corneal Grafting in MPS

MPS society June 2003

39 Clinical Mediators to Alter Amblyopia

9th International Paediatric Ophthalmology Meeting September 2003, Dublin.

40 Superior Rectus and Lateral Rectus Myopexy for High Myopia Related Esotropia .

9th International Paediatric Ophthalmology Meeting September 2003, Dublin

41 Congenital Glaucoma

22nd New Perspectives in Ophthalmology September 2003. Belfry.

42 Management Protocol for Periocular Haemangiomas International Pediatric Ophthalmology and Strabismus Conference Anaheim November 2003

43 Moderator – Session IV. Cataracts/Glaucoma International Pediatric Ophthalmology and Strabismus Conference

Anaheim November 2003

44 The Eye in Craniosynostoses Headlines Conference Coventry May 2004

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45 The Eye in Cystinosis CLIMB conference Newbury May 2004

46 The Eye in epidermolysis Bullosa

DEBRA conference Stoke-on-Trent May 2004

47 Grand Rounds

Belfast Orthoptic Meeting September 2004

48 High Frequency Ultrasound in Paediatric Ophthalmology

37th Panhellenic Ophthalmological Congress 9-13th June 2004

49 Paediatric Cataract Surgery South Coast Teaching /Training Day - Brighton June 2004

50 Superior Rectus and Lateral Rectus Myopexy for High-Myopia Related

Esotropia. ‘Hot Topics in Paediatric Ophthalmology’ RANZCO /AAPOS session at the RANZCO meeting Melbourne Nov 2004

51 Ocular Pathology in Craniosynostoses Craniofacial Disorder Symposium, International Orthoptic Congress Melbourne Nov 2004

52 Visiting Professor

Paediatric Cataract Surgery: Preoperative Evaluation and Surgical Techniques. Philippine Academy of Ophthalmology Meeting

Manila Nov 2004

53 Paediatric Glaucoma: Filtration Surgery in Children. Philippine Academy of Ophthalmology Meeting Manila Nov 2004

54 Paediatric Penetrating Keratoplasty Techniques. Philippine Academy of

Ophthalmology Meeting Manila Nov 2004

55 Complex Strabismus: Surgical Techniques. Philippine Academy of Ophthalmology Meeting Manila Nov 2004

56 Neuro-ophthalmology: Visual Loss in Craniosynostoses

Philippine Academy of Ophthalmology Meeting Manila Nov 2004

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57 Paediatric Cataract Surgery Symposium Asia Pacific Academy of Ophthalmology March 2005. Kuala Lumpur

58 Anterior Segment Diseases in Children

Asia Pacific Academy of Ophthalmology March 2005. Kuala Lumpur

59 Paediatric Cataract Surgery Instruction Course

Asia Pacific Academy of Ophthalmology March 2005. Kuala Lumpur

60 Paediatric Glaucoma Instruction Course

Asia Pacific Academy of Ophthalmology March 2005. Kuala Lumpur

61 Visiting Professor

Kellogg’s Eye Centre University of Michigan Ann Arbor, Michigan. March 2005

62 Paediatric Cataract Surgery Panel

Jack Crawford Day Hospital for Sick Children, Toronto. March 2005

63 Paediatric Cataract Instruction Course

American Association of Paediatric Ophthalmology and Strabismus Orlando March 2005

64 ECLOSA/MCLOSA Meeting London 23-26th June 2005

Interactive Head to Head Debate: Pediatric Refractive Correction. Intraocular lenses

65 Visiting Professor Peking Eye University, Beijing, China September 2005

66 Pediatric Subspecialty Day AAO Two Incision Push-Pull Rhexis for Pediatric Cataract Surgery Nov 2005.

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67 World Ophthalmology Congress February 2006 i. Pediatric Cataract Surgery Symposium : Anterior Capsulotomy

Techniques ii. Pediatric Glaucoma Symposium: Goniotomy

iii. AAPOS symposium: Pediatric Penetrating Keratoplasty iv. EPOS symposium : Surgical Aspects of Pediatric Glaucoma

68 Midland Ophthalmic Society Meeting

Common Pediatric External Disease Problems June 2006

69 Frimley Park Hospital Pediatric Ophthalmology Study Day HFU in Pediatric Ophthalmology September 2006

70 Pediatric Glaucoma Surgery HFU in Pediatric Ophthalmology Turkish Ophthalmological Society Antalya October 2006

71 Visual Morbidity in Children with Blepharokeratoconjunctivitis Pediatric Ophthalmology Subspecialty Day Pre-AAO Meeting Las Vegas Nov. 2006

72 Visiting Professor

Children’s Hospital of Philadelphia December 2006

73 National Omani Congress of Ophthalmology 2007 March 2007

74 5th Arab Regional and 8th National Jordanian Congress of Ophthalmology 2007 April 2007 Guest Lecturer

75 Royal College of Ophthalmologists Annual Meeting, May 2007

Cataract Symposium

76 International Irish Paediatric Ophthalmology Conference Dublin Sept 2007

77 Shanxi Province Ophthalmological Congress, Taiyuan City October 2007

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78 ‘Eye on the Future’ LV Prasad Eye Institute Eye Health and Disorders of Children Dec 1-2 2007 Paediatric IOL’s Paediatric PKP

79 19th Annual Jack Crawford Lecturer The Hospital for Sick Children and University of Toronto, Dept. of Ophthalmology and Vision Sciences

April 18th 2008 ‘Paediatric PKP – A Hard Graft’ 80 The Eye in Gastroenterology

Gastroenterology for General Paediatrics Institute of Child Health Oct 2-3 2008

81 Paediatric Glaucoma New Perspectives in Ophthalmology Nov 3, 2008

82 Paediatric Cataract Surgery Kuwait International Ophthalmic Congress Dec 2008

83 Visiting Expert National University of Singapore Dec 2008

84 Invited Speaker: ASIA ARVO January 2009

85 Expert Opinion in Paediatric Ophthalmology Pediatric Ophthalmology Symposium – Zurich February 2010

86 Section Head Congress of Controversies in Ophthalmology – Prague March 2010

87 Diagnosis & Treatment of Paediatric Dystrophies and Degeneration World Cornea Congress VI - Boston April 2010

88 Congenital Corneal Opacification – time for a re-think of classification 43rd Panhellenic Congress of Ophthalmology - Greece

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EPONYMOUS LECTURES 1 John Pratt Johnson Lecture Ocular Aspects of Craniosynostoses The Canadian Orthoptic Society Canadian Ophthalmic Society Meeting Toronto 2001 2 The 19TH Jack Crawford Lecturer Anterior Segment Disease and Surgery in Children The Hospital for Sick Children, Toronto April 2008 LECTURES ON COURSES 1 Institute of Child Health: MRCP Course. Paediatric Ophthalmology

May 1999,2000 2 Institute of Child Health : Practical Paediatric Neurology

January 2000,2001 3 Institute of Optometry, City University – MSc in Profound Learning Difficulties

April 2002 4 Birmingham Ophthalmic Nurses Course- Surgical Aspects of Paediatric

Ophthalmology. November 2001 5 American Association of Certified Orthoptists Course. AAO New Orleans Nov 2001. Ophthalmic Features of the Craniosynostoses 6 American Academy of Ophthalmology. Pediatric Neuro-ophthalmology Course. New Orleans November 2001 7 Institute of Child Health – Paediatric Ophthalmology and Strabismus Modules

2 Day Course. Course Founder and Co-Organiser 1999,2000,2001,20002,2003,2004

8 Institute of Child Health – Hot Topics in Paediatrics The World through the Child’s Eyes Nov 2002 9 Royal College of Ophthalmologists Higher Surgical Study Days Pediatric Cataract Surgery The Child Who Appears not to See July 2004, 2005, 2006,2007,2008,2009

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10 AAPOS WORKSHOPS 2004, 2005, 2006 Controversies in Pediatric Cataract Surgery 2003 Pediatric Corneal and External Diseases 2006 Pediatric Glaucomas 2007 The eye in metabolic disease 2008 Pediatric Cataract 2008, 2009 Managing a child with external eye disease 2010 Surgical Secrets 2010 Difficult Problems Non-Strabismus 11 AAO WORKSHOPS 2002, 2005 Pediatric Neuroophthalmology 2004 Pediatric Glaucomas 2008, 2009 Paediatric Cataract Management 12 ESCRS 2006,2007,2008,2009 Pediatric keratoplasty 2006 HSV infection in children

7 1st WORLD CONGRESS OF PAEDIATRIC OPHTHALMOLOGY AND STRABISMUS Co-founder and Organiser. Sept 2009, Barcelona.

REVIEWER FOR FOLLOWING JOURNALS 1 EYE 1999-2009 2 British Journal of Ophthalmology 2000-2010 3 Clinical Dysmorphology 2000-2002 4 Journal of AAPOS 2002-2010 5 Lancet 2000 6 Investigative Ophthalmology 2001

and Visual Science 7 American Orthoptic Journal 2004,2006,2007,2009 8 American Journal of Ophthalmology 2004, 2006,2007,2008,2009, 9 International Ophthalmology 2007 10 Clinical And Experimental Ophthalmology 2006, 2007, 2009 11 Ophthalmic Genetics 2006

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TEACHING My role as fellowship director allows me to teach both resident level and fellow level doctors. There is a fellowship education program which involves orthoptics, electrophysiology and my colleagues. There are fellows’ nights for informal discussion about one subject, regular journal clubs and Socratic style teaching seminars with weekly grand rounds. Teaching is also done for paediatricians and for nursing staff ORBIS I have been privileged to be involved with ORBIS since December 2003 I found teaching the local faculty extremely challenging and very satisfying. I am committed to the vision of Dr Helveston as regards telemedicine and its use as an educator. December 2004 Hospital Based Programme in Kunming, China. October 2005 Hospital Based Programme in Atushi, China September 2006 Hospital Based Programme in Wuhan, China September 2007 Hospital based Programme Xanjii, China September 2008 Hospital Based Shanxi Eye Hospital, China PROFESSIONAL RESPONSIBILITIES 1 International Member of the Editorial Board of the

American Orthoptic Journal 2 Member of the Scientific Advisory Committee of the International Cornelia de

Lange Foundation 3 Member of the Scientific Advisory Committee of the Cystinosis Foundation 4 Member of the Scientific Advisory Committee of the Pediatric Glaucoma and

Cataract Family Association 5 Section Editor for Paediatric Ophthalmology, British Journal of

Ophthalmology 6 International Editor Journal of Pediatric Ophthalmology and Strabismus

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7 Unit Training Supervisor, Dept. of Ophthalmology, Great Ormond St. Hospital for Children, London, England

8 Fellowship Director, Dept. of Ophthalmology, Great Ormond St. Hospital for

Children, London, England 9 BEES Committee Representative for Medicine/ Urology Directorate , Great

Ormond St. Hospital for Children, London, England 9 Member of the Council of the Section of Ophthalmology, Royal Society of

Medicine 10 Vice Chairman of the Standing Medical Advisory Committee to the

Department of Health, Government of the United Kingdom This has been one of the most satisfying non-clinical activities that I have had the privilege to undertake and participate in. Our advice is communicated directly to the Minister for Health. The subjects are varied but of great interest recently has been advice regarding the unlicensed use of medication for the paediatric population.

11 Member of the Ocular Tissues Standards and Audit Group 12 College Tutor 13 Consultation Advisor for Section on Craniopharyngioma in ‘Paediatric

Endocrine Tumours Ed. Helen Spoudeas. Oct 2005.UKCCSG and BSPED 12 Lead, Dept. of Clinical and Academic Ophthalmology, Great Ormond St Hospital for Children OTHER INTERESTS I enjoy live music immensely and golf has superceded squash as my favourite sport. Although I do not speak any African languages I have developed a great enthusiasm for African music especially from Mali, Senegal, the Ivory Coast and South Africa. I also enjoy a game of Charom (oriental game similar to billiards but played with discs on a specially constructed board).