Curriculum Vitae

David Atkinson, Ph.D.

Professor and Acting ChairDepartment of Physiology and Biophysics

Research Professor of Biochemistry

Boston University School of Medicine715 Albany StreetBoston, MA 02118

Phone: (617) 638-4015e-mail: atkinson@bu.edu

Nationality: British, U.S. Permanent Resident

Education1965-69 The City University, London, England

B.Sc.(Hons.) Applied Physics with specialization in x-ray crystallography and solid state physics

1970-75 Council for National Academic Awards, England Ph.D. Biophysics - “X-ray Studies of the Structure of Natural and

Reassembled Plasma High Density Lipoproteins”.

Positions 1969-73 Senior Research Assistant, Biophysics Division, Unilever Research,

Welwyn, England 1973-75 Scientist, Biophysics Division, Unilever Research, Welwyn, England 1975-78 Research Associate, Department of Medicine, Boston University School of

Medicine1977-81 Guest Assistant Biophysicist, Brookhaven National Laboratory 1979-82 Assistant Research Professor of Medicine, Department of Medicine, Boston

University School of Medicine 1979-82 Assistant Professor of Biochemistry, Department of Biochemistry, Boston

University School of Medicine 1980-85 Established Investigator of the American Heart Association 1980-2006 Director, Physical Equipment Core Facility, Department of Biophysics,

Boston University School of Medicine 1981-2000 Guest Associate Scientist, Brookhaven National Laboratory 1982-1990 Associate Research Professor of Medicine, Department of Medicine, Boston

University School of Medicine 1982-1989 Associate Research Professor of Biochemistry, Department of Biochemistry,

Boston University School of Medicine 1987-1988 Visiting Scholar, Division of Structural Studies, Medical Research Council

Laboratory of Molecular Biology, Cambridge, England 1989-2000 Professor of Biophysics, Department of Biophysics, Boston University

School of Medicine 1989-to date Research Professor of Biochemistry, Department of Biochemistry, Boston

University School of Medicine

1999-2000 Acting Chairman, Department of Biophysics, Boston University School of Medicine

2000-to date Professor, Department of Physiology and Biophysics, Boston University School of Medicine

2005-to date Acting Chairman, Department of Physiology and Biophysics, Boston University School of Medicine

Appointments1980-1983 Associate Editor, Journal of Lipid Research 1983-1987 Editorial Board Member, Journal of Lipid Research 1983-1985 Member, American Heart Association, New England Regional

Research Review Advisory Committee 1985-1987 Member, U.S. National Committee on Crystallography 1991- 1995 Member, Advisory Committee HFBR Brookhaven National

Laboratory 1993-1994 Selection Committee, Irvine H. Page Young Investigator

Award, American Heart Association 1995-2000 Editorial Board Member, Journal of Lipid Research 1998-2000 Member, Group on Graduate Research, Education, and

Training (GREAT), Association American Medical Colleges 2004-to date Editorial Board Member, BioMed Central, Biochemistry

Committee Appointments1982-1985 Admissions Committee for M.D./Ph.D. Applicants, School of

Medicine, Boston University School of Medicine. 1982-1985 Graduate Admissions Committee, Division of Medical and Dental Sciences,

Boston University School of Medicine. 1987-1988 Working Committee on Medical Campus Computer Networking Boston

University School of Medicine 1987-to date X-Ray Radiation Safety Committee Boston University School of

Medicine 1987-1990 Biophysics Degree Program Development Committee, Boston University

School of Medicine 1988-1989 Chairman, Department of Biophysics Faculty Search Committee, Boston

University School of Medicine 1988-2000 Executive Committee, Department of Biophysics, Boston University School

of Medicine 1988-1996 Chairman, Faculty Affairs Committee, Department of Biophysics, Boston

University School of Medicine 1989-1991 Chairman, Committee on Standard Operating Procedures, Boston University

School of Medicine 1989-1996 Computer Policy Committee, Boston University School of Medicine 1989-1992 Natural Sciences Curriculum Committee, Boston University 1995-2000 Steering Committee, Graduate Division of Medical Sciences, Boston

University School of Medicine 1996-2000 Faculty Affairs Committee, Department of Biophysics, Boston University

School of Medicine 1996-1998 BUSM 2000 Task Force on Information Technology, Boston University

School of Medicine

1996-1998 Research Administration Technology Team, Boston University School of Medicine

1996 Search Committee, Chief Information Officer, Boston University School of Medicine

1996 Member, Special Committee into Scientific Misconduct, Boston University School of Dental Medicine

1998-1999 Committee to Consider the Reorganization of Basic Sciences, Boston University School of Medicine

1999- to date Information Technology Advisory Committee, Boston University School of Medicine

2000- 2005 Admissions Committee for M.D./Ph.D. Applicants, School of Medicine, Boston University School of Medicine

2000- to date Executive Committee, M.D./Ph.D. Program, Boston University School of Medicine

2000- to date Student Executive Committee, Department of Physiology and Biophysics, Boston University School of Medicine

2005-to date Core Implementation and Oversight Committee, Boston University School of Medicine

2005- to date Executive Committee, Boston University School of Medicine

Society MembershipBritish Biophysical Society American Association for the Advancement of Science American Heart Association American Crystallographic Association Biophysical Society

Consultation and ReviewingGrant Application Reviewer for: NIH National Heart Lung and Blood Institute

National Science Foundation American Heart Association Canadian Heart Association

External Advisory Board, Program Project Grant – Jere Segrest PI, University of Alabama, Birmingham

Manuscript Reviewer for Journals: Acta Crystallographica Biochemistry Biochimica et Biophysica Acta Biophysical Journal Gastroenterology Journal of Lipid Research Journal of Biological Chemistry Nature Science

Research Support and Funding

1980 Research Career Development Award NIH (declined in favor of AHAAward)

1980-1985 Established Investigator, American Heart Association 1980-1997 Preceptor, Training Grant N.I.H/NHLBI 1980-to date Project Leader, Project 3: Lipoprotein Structure and Apoprotein

Conformation, Program Project: Structural and Cell Biology in Cardiovascular Disease N.I.H/NHLBI

1980-to date Director Physical Equipment Core Facility, Program Project: Structural and Cell Biology in Cardiovascular Disease, N.I.H/NHLBI

1984-1985 Whitaker Foundation Collaborative Award 1985 Co-investigator, Molecular Modeling Resource SIG, N.I.H/NDDR 1994-to date Co-Investigator, Molecular and functional analysis of human apoA-1

NIH/NHLBI 1994-1998 Preceptor, Predoctoral Training in Molecular Biophysics NIH/NIGMS 1995-to date Co-Investigator, Molecular and functional analysis of human apoA-1

NIH/NHLBI 1996-to date Preceptor, Basic Sciences Cardiovascular Postdoctoral Training Program

NIH/NHLBI1997-to date Preceptor, Structural and Cell Biology in Cardiovascular Systems, Training

Grant NIH./NHLBI1997-to date Preceptor, Predoctoral Training in Biomolecular Pharmacology

NIH/NIGMS1998 Co-investigator, Electron Microscopy Facility SIG, NIH/NDDR 2000 Co-investigator, Electron Microscopy Facility SIG, NIH/NDDR 2001 Co-investigator, X-ray Crystallography SIG, NIH/NDDR 2001-to date Principle Investigator, Program Project Grant: Structural and Cell Biology

In Cardiovascular Disease. NIH/NHLBI

Supervision and Teaching General

Teaching (didactic) and supervision of graduate students, Boston University School of Medicine Teaching (lecturer) Preclinical Biochemistry - School Dental MedicineGraduate Qualifying Examination CommitteesPh.D. Dissertation Committees

Teaching

Foundations of Biophysics and Structural BiologyGMS BY 760 – Department of Physiology and Biophysics Course Director and Lecturer 14 Lecture hours, Spring Semester

Biophysics of Macromolecular AssembliesGMS BY 771 – Department of Physiology and BiophysicsLecturer 10 Lecture hours, Fall Semester

Experimental Methods in Physiology GMS PH 741 – Department of Physiology and Biophysics Lecturer 4 Lecture hours, Fall Semester

Biochemistry - Lipid and lipoprotein metabolism and Biological Membranes SDM MD 512 - School Dental Medicine: Lecturer 10 Lecture hours, Fall Semester

The Excel Program Biochemistry, School of Dental Medicine Summer Program Lecturer 19 Lecture hours / 2 weeks (July)Endocrinology GMS PH 748 - Graduate Medical Sciences and School of MedicineLecturer1 lecture hour, Spring Semester

Physiology/Endocrinology/Neurophysiology SDM MD 514, School Dental MedicineLecturer3 Lecture hours, Spring Semester

Graduate Student Supervision, Boston University School of Medicine:

Graduated Students Geoffrey Ginsburg, M.D./Ph.D 1985 "Lipid-Lipid and Lipid-Protein

Interactions in Model Systems of Low Density Lipoprotein"

Robert Reisinger

Joan Richmond, Ph.D 1994 "The Conformation of Apolipoproteins A-1 and B-100 on Native, Modified, and Model Lipoprotein Probed byMonoclonal Antibody Epitope Expression"

Robert Nolte, Ph.D. 1993 "Structural Analysis of the Human Apolipoproteins: An Integrated Approach utilizing Physical and Computational Methods"

Victoria Ziemba, M.A 1987 "Properties of Mixed Phosphadidylycholines"

Joshua. Spin, M.D./Ph.D. 1997 "Cryo-electron Microscopy Studies of Low Density Lipoprotein in Vitreous Ice"

George Poulos, M.A. 1995 "Computerized Simulated Annealing Structure Determination of Apolipoprotein Consensus Sequence Peptides"

George Poulos, M.D./Ph.D. 2000 "The Three-Dimensional Structureof Low Density Lipoprotein via Cryo-electron Microscopy"

Yang Chao, Ph.D. 2002 "Conformational Studies of a Consensus Sequence Peptide (CSP) and a Real Sequence Peptide (RSP) ofApolipoproteins by Circular Dichroism and X-ray Crystallography"

Yiling Fang, Ph.D. 2002 "Structural Studies of N and C terminally Truncated Human Apolipoprotein A-1"

Hassan Khafche, Ph.D. 2002 "Spectroscopic and CalorimetricStudies of the 17% N-Terminal Domain of Apolipoprotein B-100"

Jeremy Wally, Ph.D. 2004 “Conformation and Lipid BindingProperties of Peptide Models of Exchangeable Apolipoproteins”

Hongli Zhu, Ph.D 2006 “Structure, Interaction and LipidBinding of Sub-Domains of Human Apolipoprotein A-1”

Current Ph.D. Students Dong LuoXiahu Mei Yuhang Liu

Post Doctoral (Research Associate) Supervision

Mary Walsh, Ph.D 1980-1984 Darhma Kodali, Ph.D 1982-1985 Olga Gursky, Ph.D 1994-1996 Irina Gorshkova, Ph.D. 1998- to date

Bibliography

Original Articles

1. Small-angle x-ray scattering of human serum high density lipoproteins. G.G. Shipley, D. Atkinson and A.M. Scanu. Journal of Supramolecular Structure (1972) 1:98:104.

2. The structure of a high-density lipoprotein (HDL3) from porcine plasma. D. Atkinson, M.A.F. Davis and R.B. Leslie. Proceedings of the Royal Society, London, B. (1974) 186:165-180.

3. Structure and morphology of phosphatidylserine dispersions. D. Atkinson, H. Hauser, G.G. Shipley and J.M. Stubbs. Biochimica Et Biophysica Acta (1974) 339:10-29.

4. The structure, physical and chemical properties of the soy bean protein glycinin. R.A. Badley, D. Atkinson, H. Hauser, D. Oldani, J.P. Green and J.B. Stubbs. Biochimica et Biophysica Acta (1975) 42:214-228.

5. X-ray studies of the structure of natural and reassembled plasma high density lipoproteins. D. Atkinson, Ph.D. Thesis. Council for National Academic Awards, England (1975).

6. Interaction of apoprotein from porcine high density lipoprotein with dimyristoyl lecithin, 1 - The structure of The complexes. D. Atkinson, H.M. Smith, J. Dickson and J.P. Austin. European Journal of Biochemistry (1976) 64:549-563.

7. Interaction of apoprotein from porcine high density lipoprotein with dimyristoyl lecithin, 2 - Nature of lipid-protein interactions. A.L. Andrews, D. Atkinson, M.D. Barratt, E.G. Finer, H. Hauser, R. Henry,R.B. Leslie, N.L. Owens, M.C. Phillips and R.N. Robertson. European Journal of Biochemistry (1976) 64:549-563.

8. The structure of plasma low-density lipoproteins: The molecular organization of the central core. D. Atkinson, R.J. Deckelbaum, G.G. Shipley and D.M. Small. Proceedings of the National Academy of Sciences (1977) 74:1042-1046.

9. The conformation and aggregation of bovine B-casein A. Part I. Molecular aspects of thermal aggregation. A.L. Andrews, D. Atkinson, M.T.A. Evans, E.G. Finer, J.P. Green, M.C. Phillips And R.N. Robertson. Biopolymers (1979) 18:1105-1121.

10. Characterization of the lipoproteins of atherosclerotic swine. A.R. Tall, D. Atkinson, D.M. Small and R.W.Mahley. Journal of Biological Chemistry (1977) 252:7288-7293.

11 The structural organization of the lipoprotein HDLc from atherosclerotic swine. Structural features relating the particle surface and core. D. Atkinson, A.R. Tall, D.M. Small And R.W. Mahley. Biochemistry (1978) 17:3930-3933.

12. Structure of atherogenic low density lipoproteins from Macacca Fasicularis. A.R. Tall, L.L. Rudel, D.M. Small and D. Atkinson . Journal of Clinical Investigation (1978) 62:1354-1363.

13. X-ray and neutron scattering studies of plasma lipoproteins. D. Atkinson, D.M. Small and G.G. Shipley. Annals of New York Academy of Sciences - Lipoprotein Structure (1980) 348:284-288.

14. Organization of the core lipids of high density lipoproteins in the lactating bovine. A.R. Tall, D.L. Puppione, S.T. Kunitake, D. Atkinson, D.M. Small and D. Waugh. Journal of Biological Chemistry (1981) 256:170-174.

15. X-ray diffraction and calorimetric study of anhydrous and hydrated N-palmitoyl galactosylceramide (cerebroside). M.J. Ruocco, D. Atkinson, D.M. Small, R.P. Skarjune, E. Oldfield and G.G. Shipley. Biochemistry (1981) 20:5957-5966.

16. Physical studies of d>1.006 g/ml lymph lipoproteins from rats fed palmitate-rich diets. S.B. Clark, D. Atkinson, J.A. Hamilton, T. Forte, B. Russell, E.B. Feldman and D.M. Small. Journal of Lipid Research (1982) 23:28-41.

17. Physical characterization of lymph chylomicrons and very low density lipoprotein from non-human primates fed saturated dietary fat. J.S. Parks, D. Atkinson, D.M. Small and L.L. Rudel. Journal of Biological Chemistry (1982) 256:12992-12999.

18. Microemulsions of Phospholipids and Cholesterol Esters: Protein-free models of low density lipoprotein. G.S. Ginsburg, D.M. Small and D. Atkinson. J. Biol. Chem. (1982) 257:8216-8227.

19. Solubilization of Low Density Lipoprotein with Sodium Deoxycholate and recombination of apoB with Dimyristoyl Lecithin. M. Walsh and D. Atkinson. Biochemistry (1983) 22:3170-3178.

20. Models of plasma low density lipoprotein: Phospholipid-cholesterol ester-apoprotein B complexes. G.S. Ginsburg, M.T. Walsh, D.M. Small and D. Atkinson. J. Biol. Chem. (1984) 259:6668-6673.

21. Thermal transitions and structural properties of synthetic cholesterol alkyl esters: Analogues of biological cholesterol esters. R.J. Deckelbaum, G. Halperin and D. Atkinson. J. Lipid Res. (1983) 24:657-661.

22. Physical properties of apoprotein B in mixed micelles with sodium deoxycholate and in a vesicle with dimyristoyl phosphatidylcholine. M.T Walsh and D. Atkinson. J. Lipid Res. (1986) 27:316-325.

23. Synthesis and polymorphism of 3-acyl-sn-glycerols. D.R. Kodali, T.G. Redgrave, D. Atkinson and D.M. Small. Biochemistry (1984) 24:519-525.

24. Synthesis and polymorphism of 1,2-dipalmitoyl-3-acyl-sn-glycerols. D.R. Kodali, D. Atkinson, T.G. Redgrave and D.M. Small. J.A.O.C.S. (1984) 61(6):1078-1084.

25. Physical properties of cholesterol esters. G.S. Ginsburg, D. Atkinson and D.M. Small. In Progress in Lipid Research (1984) 23:135-167.

26. Structure and polymorphism of 1,2-dioleoyl-3-acyl-sn-glycerols three- and six-layered structures. D. Fahey, D.M. Small, D. Atkinson, D.R. Kodali and T.G. Redgrave. Biochemistry (1985) 24:3757-3764.

27. The phase behavior and bilayer properties of fatty acids: hydrated 1:1 acid soaps. D.P. Cistola, D. Atkinson, J.A. Hamilton and D.M. Small. Biochemistry (1986) 25:2804-2812.

28. X-ray scattering of vesicles of N-acyl sphingomyelins: Determination of bilayer thickness. P.R. Maulik, D. Atkinson and G.G. Shipley. Biophys. J. (1986) 50:1071-1077.

29. Structure and polymorphism of 18-carbon fatty acyl triacylglycerols: The effect of unsaturation and substitution in the 2-position. D.R. Kodali, D. Atkinson and D.M. Small. J. Lipid Res. (1987) 28: 403-413.

30. Synthetic high density lipoprotein particles: Application to studies of the apoprotein specificity for selective uptake of cholesterol esters. R.C. Pittman, C.A. Glass, D. Atkinson and D.M. Small. J. Biol. Chem. (1987) 262:6 2435-2442.

31. The complete sequence and structural analysis of human apolipoprotein B: Relationship between apoB-100 and apoB-48 forms. C. Cladaras, M. Cladaras, R.T. Nolte, D. Atkinson and V. Zannis. The EMBO Journal (1987) 15:3495-3507.

32. Influence of different molecular species of phosphatidylcholine on cholesterol transport from lipoproteins in the rat. R. Leduc, G.M. Patton, D. Atkinson, and S. Robins. J. Biol. Chem (1987) 262:16 7680-7685.

33. Influences of acyl chain length and unsaturation on the molecular packing of fats. D.R. Kodali, D. Atkinson, and D.M. Small. (1988) J. Disp. Sci. Tech. 10:393-440.

34. Molecular packing of 1,2-dipalmitoyl-3-decanoyl-_sn_-glycerol (PP10): Bilayer, Trilayer and hexalayer structures. D.R. Kodali, D. Atkinson, and D.M. Small. (1989) J. Phys. Chem. 93(11):4683-4691.

35. Molecular properties of glycerol derivatives. D.R. Kodali, D. Atkinson, and D.M. Small. (Proceedings 15th Scandinavian Symposium on Lipids, Rebild Bakker, Denmark, 11-15 June, 1989) Lipidforum pp. 86-102.

36. Influences of acyl chain length and unsaturation on the molecular packing of fats. D.R. Kodali, D. Atkinson, and D.M. Small. (1988) Proceedings of the 1988 Nara Workshop on Functional Fats and Lipids, Oct. 4-6, 1988, Nara, Japan. The Society of Fats and Lipids Research and the Japan Oil Chemist's Society, pp. 95-121.

37. Polymorphic behavior of 1,2-dipalmitoyl-3-lauroyl (PP12) and myristoyl (PP14)-_sn_-glycerols. D.R. Kodali, D. Atkinson and D.M. Small. (1990) J. Lipid Res. 31(10):1853-1864.

38. Phospholipid/cholesteryl ester microemulsions containing unesterified cholesterol: A protein free model system for low density lipoproteins. R.E. Reisinger and D. Atkinson. (1990) J. Lipid Res. 31(5):849-858.

39. Calorimetric and spectroscopic investigation of the unfolding of human apolipoprotein B. M.T. Walsh and D. Atkinson. (1990) J. Lipid Res. 31(6):1051-1062.

40. Conformational analysis of apolipoprotein A-I and E-3 based on primary sequence and circular dichroism. R.T. Nolte and D.A tkinson. (1992) Biophys. J. 63:1221-1239.

41. Cryoelectron microscopy of low density lipoprotein in vitreous ice. J.M. Spin and D. Atkinson. (1995) Biophys. J. 68:2115-2123.

42. Thermal unfolding of human plasma apolipoprotein A-1: Implications for a physiological molten globular state. O. Gursky and D. Atkinson. (1995) Proc. Natl. Acad. Sci. USA 93:2991-2995.

43. High-and-low-temperature unfolding of human high-density apolipoprotein A-2. O. Gursky and D. Atkinson. (1996) Protein Science. 5:1874-1882.

44. Irina N. Gorshkova, Kalliopi Liadaki, Olga Gursky, David Atkinson, and Vassilis I. Zannis. Probing the lipid-free structure and stability of apolipoprotein A-I by mutation. Biochemistry, 39(51): 15910-15919, 2000.

45. Irina N. Gorshkova, Tong Liu, Vassilis I. Zannis, and David Atkinson. Lipid-Free Structure and Stability of Apolipoprotein A-1: Probing the Central Region by Mutation. Biochemistry, 41(33): 10529-10539, 2002.

46. Fang Y, Gursky O, Atkinson D . Structural studies of N- and C-terminally truncated human apolipoprotein A-I. Biochemistry. 2003, 42(22):6881-90.

47. Fang Y, Gursky O, Atkinson D . Lipid-Binding Studies of Human Apolipoprotein A-I and Its Terminally Truncated Mutants. Biochemistry. 2003, 42(45), 13260-13268.

48.Libo Wang, David Atkinson and Donald M. Small. Interfacial Properties of an Amphipathic -Helix Consensus Peptide of Exchangeable Apolipoproteins at Air/Water and Oil/Water Interfaces. J. Biol. Chem., Vol. 278, Issue 39, 37480-37491, September 26, 2003.

49.Hongli L. Zhu and David Atkinson. Conformation and Lipid Binding of the N-Terminal (1-44) Domain of Human Apolipoprotein A-I Biochemistry; 2004; 43(41) pp 13156 – 13164

50. Libo Wang, David Atkinson and Donald M. Small. The Interfacial Properties of ApoA-I and an Amphipathic a-Helix Consensus Peptide of Exchangeable Apolipoproteins at the Triolein/Water Interface. J. Biol. Chem., Vol. 280, Issue 6, 4154-4165, 2005

51. Irina N. Gorshkova, Tong Liu, Horng-Yuan Kan, Angeliki Chroni, Vassilis I. Zannis, and David Atkinson. Structure and Stability of Apolipoprotein A-I in Solution and in Discoidal High-Density Lipoprotein Probed by Double Charge Ablation and Deletion Mutation. Biochemistry; 2006; 45(4) pp 1242 - 1254;

Chapters and Reviews

1. Lipid organization in human plasma low density lipoproteins. G.G. Shipley, R.J. Deckelbaum, D. Atkinson and D.M. Small. Atherosclerosis IV, Proceedings of the IVth International Symposium on Atherosclerosis, Tokyo, Japan (1976) (eds. G. Schettler, Y.Goto, Y. Hata, G. Klose) Springer-Verlag, NY.

2. A biophysical approach to cholesterol transport from tissues to bile. D.M. Small, D. Atkinson, T. Redgrave, G.G. Shipley and A.R. Tall. 4th International Symposium on Gallstones, Montreal, Canada (1978) in Hepatology-Research and Clinical Issues, Vol. 4, Plenum Press.

3. Structural studies of plasma lipoproteins. D. Atkinson and G.G. Shipley. Brookhaven Symposium in Biology, 32 Neutrons in Biology. Neutron Scattering Analysis for Biological Studies. P.B. Schoenborn, ed., Plenum Publ. (1984) pp. 211-226.

4. Physicochemical studies on the position of molecules in emulsions and membranes. D.M.. Small, K. Miller, D. Cistola, G. Ginsburg, J. Parks, D. Atkinson and J.A. Hamilton. Falk Symposium 33, in Bile Acids and Cholesterol in Health and Disease (eds. G. Paumgartner, A. Stiehl and W. Gerok) MTP Press, Ltd. (1983)

5. Reassembly of low density lipoproteins. M.T. Walsh and D. Atkinson. Chapter in Methods in Enzymology - Plasma Lipoproteins, Vol. 128. (eds. J.P. Segrest and J.J. Albers) Academic Press, Inc. (1986) p. 582.

6. Recombinant lipoproteins implication for structure and assembly of native lipoproteins. D. Atkinson and D.M. Small. 1985 Annual Reviews of Biophysics and Biophysical Chemistry, Vol. 15. (eds. D.M. Engelman, C.R. Cantor and T.D. Pollard) Annual Reviews, Inc. (1986) pp. 403-450.

7. Secondary and tertiary structure of apolipoproteins. 49th International Colloquium on Atherosclerosis. M.T. Walsh, J.A. Hamilton, D. Atkinson, and D.M. Small. Eicosanoids, Apolipoproteins, Lipoprotein Particles and Atherosclerosis (ed. C. Malmendier) Plenum Publishing Co. (1988) pp. 123-132.

8. Apolipoprotein structure: crystals and models. D. Atkinson. Current Opinion in Structural Biology, Vol. 2, Current Biology, Ltd. (1992) pp. 483-500.

Works in Progress

1. The Tree-Dimensional Structure of Low Density Lipoprotein via Cryo-Electron Microscopy. Joshua Spin, George Poulos and David Atkinson.

2. Conformation and Lipid BindingProperties of Consensus Sequence Peptide Models of Exchangeable Apolipoproteins. Yang Chao, Jeremy Wally, and David Atkinson.

3. Conformation and Lipid Binding of Peptides Modeling Re-Arrangements of the Consensus Sequence Motif of Exchangeable Apolipoproteins. Dong Luo and David Atkinson

3. Conformation and Lipid Binding Properties of Overlapping Sequence Peptide Models of Exchangeable Apolipoproteins. Jeremy Wally and David Atkinson

Abstracts

1. Small-angle x-ray scattering of lipids and lipoproteins. G.G. Shipley and D. Atkinson. Abstracts: 2nd International Small Angle X-Ray Scattering Conference. Graz, Austria (1970). Journal of Applied Crystallography (1971) 4:417-418.

2. Small-angle x-ray scattering of human serum lipoprotein HDL. G.G. Shipley, D. Atkinson and A.M. Scanu. Abstracts: 16th Annual Biophysical Society Meeting, Canada (1972).

3. Small-angle x-ray scattering studies of porcine plasma lipoproteins. D. Atkinson and J.P. Green. Abstracts: 3rd International Conference on X-Ray and Neutron Small-Angle Scattering, Grenoble, France (1973). Journal of Applied Crystallography (1974) 7:179.

4. Solution studies of the structure and aggregation of globular proteins. D. Atkinson. Abstracts: 12th Prague Microsymposium on Macromolecules - Organized Structures in Polymer Solutions and Gels, Prague, Czechoslovakia

5. Interaction of apoprotein from porcine high-density lipoprotein with dimyristoyl lecithin: The structure of the complexes. D. Atkinson, H.M. Smith, J. Dickson and J.P. Austin. Abstracts: 20th Annual Biophysical Society Meeting, Seattle, Washington (1976) Biophysical Journal (1976) 16:192a.

6. Characterization of the lipoproteins of atherosclerotic swine. A.R. Tall, D. Atkinson, D.M. Small and R.W. Mahley. Clinical Research (1977) 25:500a.

7. Small-angle x-ray scattering studies of the cholesterol ester organization in plasma lipoproteins. D. Atkinson, A.R. Tall, R.J. Deckelbaum, G.G. Shipley and D.M. Small Abstracts: 4th International Conference on Small Angle Scattering of X-rays and Neutrons. Gatlinburg, USA (1977).

8. Structure of atherogenic low density lipoprotein. A.R. Tall, L. Rudel, D.M. Small and D. Atkinson. Abstracts: 51st American Heart Association Meeting, Dallas, Texas. Circulation (1978) 57/58, II170.

9. Structural studies of recombinant lipoproteins. D. Atkinson, G.G. Shipley and D.M. Small. Abstracts: 8th Annual ICN-UCLA Symposia Molecular and Cellular Biology, Keystone, USA (1979). Journal of Supramolecular Structure (1979) Supp. 3, 120.

10. Neutron small-angle scattering of reassembled plasma lipoproteins. D. Atkinson, D.M. Small, G.G. Shipley. Meeting of American Crystallographic Association, Boston, MA (1979)

11. Neutron scattering studies of HDL discs: Location of the apoprotein. G.G. Shipley, D.M. Small and D. Atkinson. 5th International Symposium on Atherosclerosis (1979) Houston, Texas

12. Localization of the apoprotein at the periphery of HDL disks: A model for nascent HDL. D. Atkinson, D.M. Small and G.G. Shipley. 52nd Scientific Sessions, American Heart Association (1979). Circulation 59/60, Supp. II:II-217/846a (1979).

13. X-ray and neutron scattering studies of plasma lipoproteins. D. Atkinson, D.M. Small and G.G. Shipley. Abstracts: Conference on Lipoprotein Structure, New York Academy of Sciences (1979).

14. X-ray and neutron scattering studies of plasma lipoproteins. G.G. Shipley, D.M. Small and D. Atkinson. Abstract: EMBO Meeting on Small Angle X-Ray and Neutron Scattering in Biology, Hamburg, Germany (1979).

15. Crystallization of a metastable lipoprotein. Massive change of lipoprotein properties during routine preparation. D.M. Small, D.L. Puppione, M.L. Phillips, D. Atkinson, J.A. Hamilton and D.N. Schumaker. 53rd Scientific Sessions, American Heart Association Meeting, Miami Beach Florida, November, 1980. Circulation 62, Supp. III (1980) III-118/444.

16. X-ray diffraction and calorimetric study of anhydrous and hydrated N-palmitoyl galactosylceramide. M. Ruocco, D. Atkinson, D.M. Small, R. Skarjune, E. Oldfield and G.G. Shipley. Abstracts: 25th Annual Biophysical Society Meeting, Denver, Colorado (1981). Biophysical Journal (1981).

17. Physical Studies of d1.006 g/ml lymph lipoproteins from rats fed saturated fats. S. Bennett Clark, E.B. Feldman, D. Atkinson, J.A. Hamilton, T. Forte and D.M. Small. Abstract: National A.S.C.I. Meeting, San Francisco, California (1981). Clinical Research (1981).

18. Physical Studies of chylomicra (CM) from monkeys fed saturated fat. J. Parks, J. Hamilton, D. Atkinson, D.M. Small and L. Rudel. Abstract: American Society of Biological Chemists Meeting, Atlanta, Georgia (1981) Federation Proceedings (1981).

19. Solubilization of LDL by sodium deoxycholate and recombination of apoB with dimyristoyl phosphatidylcholine. M. Walsh and D. Atkinson. Abstracts: 54th Scientific Sessions, American Heart Association, Dallas, Texas. Arteriosclerosis (1981) 396a; Circulation 1/#5:396a (1981)

20. Microemulsion of cholesterol ester and phospholipids: Protein-free models of LDL. G. Ginsburg, D.M. Small and D. Atkinson. 54th Scientific Sessions, American Heart Association, Dallas, Texas (1981) Arteriosclerosis (1981) 1:378a.

21. Solubilization of low density lipoprotein (LDL) by sodium deoxycholate (NaDC) and recombination of apoB with dimyristoyl phosphatidylcholine (DMPC): Preparative method and physical studies. M.T. Walsh and D. Atkinson. Abstracts: 1982 Biophysical SocietyMeeting, Boston, Massachusetts. Biophysical Journal (1982) 37, 2 part 2, 100g.

22. Microemulsions of cholesterol esters (CE) and phospholipids (PL): Protein-free models of low density lipoproteins (LDL). G.S. Ginsburg D.M. Small and D. Atkinson. Abstracts: 1982 Biophysical Society Meeting, Boston, Massachusetts. Biophysical Journal (1982) 37, 2 part 2, 100g.

23. Lipoprotein Models: Interaction of apolipoproteins with phospholipid (PL)/cholesterol ester (CE) microemulsions. G.S. Ginsburg, D.M. Small and D. Atkinson. Abstracts: 1982 FASEB Meetings, New Orleans, Louisiana. Federation Proc. 41:4392a/1021 (1982)

24. ApoB-Lecithin-Cholesterol Ester Complexes: Reassembly of LDL. M.T. Walsh, G.S. Ginsburg, D.M. Small and D. Atkinson. 55th Scientific Sessions of American Heart Association. November, 1982.

25. The phase behavior of anhydrous and hydrated 1:1 potassium hydrogen dioleate. D.P. Cistola, D.M. Small, D. Atkinson and J.A. Hamilton. Acid soaps. American Oil Chemists Society Meeting, Chicago, Illinois, May 8-12, 1983.

26. Synthesis and polymorphism of 1,2-dipalmitoyl 3-acyl-sn-glycerol series. D.R. Kodali, T.G. Redgrave, D.M. Small, D. Atkinson. (Indian Science Congress Association, Calcutta, India). 70th Session of Science Congress, Tirupati, January 3-8, 1983.

27. Small angle x-ray scattering (SAXRS) of dimyristoyl lecithin (DML)/cholesterol oleate (CO) microemulsions: Structural analogues of low density lipoprotein (LDL). G.S. Ginsburg and D. Atkinson . 27th Biophysical Society Annual Meeting, San Diego, California, February 13-16, 1983. Biophys. J. 41:M-PM-Pos55/50a, 1983.

28. Physicochemical Studies on the Position of Molecules in Micelles, Membranes and Emulsions. D.M. Small, K. Miller, D. Cistola, G. Ginsburg, J. Parks, D. Atkinson and J.A. Hamilton. VIIth International Bile Acid Meeting (Basel Liver Week - Bile Acids and Cholesterol in Health and Disease) Basel, Switzerland. October 12-18, 1982.

29. ApoB-lecithin (L)-cholesterol ester complexes: Reassembly of LDL. M.T. Walsh, G.S. Ginsburg, D.M. Small and D. Atkinson. 55th Scientific Session, American Heart Association Meeting, Dallas, Texas , November 15-18, 1982. Arteriosclerosis 2(5)445a.

30. Human gallbladder mucin enhances in vitro nucleation of cholesterol monohydrate crystals. P. Levy, B.F. Smith, D. Atkinson and J.T. LaMont. AASLD Meeting, Washington, DC, May 23-25, 1983.

31. Lipid composition and physical state influence the binding and conformation of apoproteins. M.T. Walsh, G. Ginsburg, D. Atkinson. 57th Scientific Session, American Heart Association Meeting. Miami, Florida, November 12-15, 1984. Circulation 70, Supp. II 315/1250.

32. Bilayer-bilayer and bilayer-trilayer transitions of 1,2-dipalmitoyl-3-decanoyl-sn-glycerol (PPD). D.R. Kodali, D. Atkinson, T.G. Redgrave and D.M. Small. ASPET-ACS-DMS Meeting, Boston, Massachusetts. May 3, 1985.

33. The phase behavior and bilayer properties of fatty acids: Hydrated 1:1 acid-soaps. D.P. Cistola, D. Atkinson and J.A. Hamilton. 29th Biophysical Society Annual Meeting, Baltimore, Maryland, February 24-28, 1985. Biophys. J. 47:M-PM-C6/45a, 1985.

34. X-ray scattering of N-acyl sphingomyelin vesicles. Determination of lipid thickness. P.R. Maulik, D. Atkinson and G.G. Shipley. 30th Annual Meeting of the Biophysical Society, San Francisco, California, February 9-13, 1986.

35. Influence of acyl chain length on the molecular packing of 1,2-dipalmitoyl-3 short acyl chain sn-glycerols in a and b'-phases. D.R. Kodali, D.M. Small and D. Atkinson. 30th Annual Meeting of the Biophysical Society, San Francisco, California, February 9-13, 1986. Biophys. J. 49:T-POS-220/324a.

36. Stability of the trilayer vs. bilayer structure in 18 carbon FA triacylglycerols: The effect of unsaturation and substitution in the 2-position. D.R. Kodali, D. Atkinson and D.M. Small. 30th Annual Meeting of the Biophysical Society, San Francisco, California, February 9-13, 1986. Biophys. J. 49:T-POS-221/324a.

37. Protein-free models for low density lipoproteins (LDL): Phospholipid/cholesteryl ester microemulsions containing esterified cholesterol. R.E. Reisinger and D. Atkinson. 59th Scientific Session, American Heart Association Meeting, Dallas, Texas, November 17-20, 1986. Atherosclerosis 6:5 522a.

38. Surface phospholipid composition of microemulsions influences the binding and stoichiometry of apoprotein B on reassembled LDL complexes. M.T. Walsh and D. Atkinson. 59th Scientific Session, American Heart Association Meeting, Dallas, Texas, November 17-20, 1986. Atherosclerosis 6:5 522a.

39. Effect of 3-acyl chain length on the molecular packing of 1,2-dipalmitoyl-3-acyl-sn-glycerols. D.R. Kodali, D. Atkinson and D.M. Small. 77th Annual Meeting of the American Oil Chemists Society, Honolulu, Hawaii, May 14-18, 1986, J.A.O.C.S. 63(4):314.

40. The physical behavior of fatty acids, acid-soaps and soaps. D.M. Small, J.A. Hamilton, D. Cistola and D. Atkinson. 5th International Conference on Surface and Colloid Science, and 59th Colloid and Surface Science Symposium, Potsdam, New York, June 24-28, 1985. 1985/124a.

41. X-ray scattering of N-acyl sphingomyelin vesicles. Determination of lipid thickness. P.R. Maulik, D. Atkinson and G.G. Shipley. American Crystallographic Association Annual Meeting. McMaster University, Hamilton, Ontario, Canada, June 22-27, 1986. 14(2): K3/44.

42. Structure of plasma lipoproteins and lipoprotein models. D. Atkinson and G.S. Ginsburg. American Crystallographic Association Annual Meeting. McMaster University, Hamilton, Ontario, Canada, June 22-27, 1986. 14(2):K7/45.

43. Protein-free model systems for low density lipoproteins: Phospholipid/cholesterol ester/cholesterol microemulsions. R.E. Reisinger and D. Atkinson. 60th Scientific Sessions, American Heart Association Meeting, Anaheim, CA, November 16-19, 1987.

44. Microemulsion model systems for low density lipoproteins: A 13C NMR study. R.E. Reisinger, D. Atkinson and J.A. Hamilton. 32nd Annual Meeting of the Biophysical Society, Phoenix, AZ, February 28-March 3, 1988. Biophys. J. 53:M-POS-32/78a.

45. Rat apolipoprotein A-I (A-I) epitope expression is influenced by lipid environment. J.F. Richmond, M.T. Walsh, C. Glass and D. Atkinson. 61st Scientific Sessions, American Heart Association Meetings, Washington, DC, November 14-17, 1988.

46. Secondary and tertiary structure of apolipoproteins. M.T. Walsh, J.A. Hamilton, D. Atkinson and D.M. Small. (1988) 49th International Colloquium on Atherosclerosis.

47. Electron microscopy of unstained, frozen hydrated low density lipoprotein. D. Atkinson 61st Scientific Sessions, American Heart Association Meetings, Washington, DC, November 14-17, (1988) Arteriosclerosis 8(5) 598a. Circulation 78(4) Part II, II-287/1143a.

48. Electron microscopy of unstained, frozen hydrated low density lipoprotein. D. Atkinson (1989), 33rd Annual Biophysical Society Meeting, Cincinnati Ohio.

49. Phospholipid/cholesterol ester/cholesterol/apoprotein A-1 microemulsions: Lipid-protein model systems for human serum lipoproteins. (1989), R.E. Reisinger, and D. Atkinson. 33rd Annual Biophysical Society Meeting, Cincinnati Ohio.

50. Influences of acyl chain length and unsaturation on the molecular packing of fats. D.R. Kodali, D. Atkinson, and D.M. Small. (1988) Proceedings of the 1988 NARA workshop on functional fats and lipids, Japan. The Society of Fats and Lipids Research and The Japan Oil Chemists' Society.

51. Calorimetric and spectroscopic studies of the unfolding of apolipoprotein B (apoB). M.T. Walsh and D. Atkinson. (1989) 34th Annual Biophysical Society Meeting, Baltimore, Maryland. Biophys. J. 57/415a.

52. Molecular properties of glycerol derivatives. D.R. Kodali, D. Atkinson, and D.M. Small. (1989) 15th Scandinavian Symposium on Lipids, Jutland, Denmark B2/11.

53. Physicochemical, homology, CD, and secondary structure analysis of human apolipoproteins A-I, A-IV, and E-3. R.T. Nolte and D. Atkinson. (1990) 35th Annual Biophysical Society Meeting, San Francisco California.

54. Conformational analysis of a peptide model of the human apolipoproteins. R.T. Nolte and D. Atkinson. (1992) 37th Annual Biophysical Society Meeting, Washington D.C. Biophys. J. 64(2):W-POS200/A285.

55. Structure of low density lipoprotein in vitreous ice. J.M. Spin and D. Atkinson. (1992) 37th Annual Biophysical Society Meeting, Washington D.C. Biophys. J. 64(2):W-POS202/A286.

56. Solution structure of a 44 residue consensus peptide of apolipoproteins by NMR. F. Zhang, G. Poulos, J.A. Hamilton and D. Atkinson. (1995) Biophysical Society Meetings.Biophys. J. 68(2):Th-POS308/A420.

57. Gursky O. and D. Atkinson. Thermal unfolding of human high-density apolipoproteins A-I and A-2: Implications for a physiological molten globular state.(1996) 40-th Annual Biophysical Society Meeting, Baltimore, MD, Feb. 17-21. Abstract: Biophys. J. 1996 70(2):A26.

58. Thermal unfolding of human plasma apolipoprotein A-1: Implications for molten globular state. Olga Gursky and D. Atkinson. (1995) 50th Calorimetry Conference, National Institute of Standards and Technology - U.S. Department of Commerce, Technology Administration, Gaithersburg, MD.

59. Chao Y., O. Gursky, and D. Atkinson. Conformational study of a consensus sequence peptide (CSP) of apolipoproteins by CD and x-ray crystallography.(1998) 42-nd Annual Biophys. Society Meeting, Kansas City, Feb. 13-16. Abstract: Biophys. J. 1998, 74(2):A279

60. Chao Y., O. Gursky, and D. Atkinson. Conformational study of a consensus sequence peptide (CSP) of apolipoproteins by CD and x-ray crystallography.(2000) 44-th Annual Biophys. Society Meeting, New Orleans, LA, Feb. 12-16. Abstract: Biophys. J. 2000, 78(1/2):484A, #2848.

61. Fang Y., O. Gursky, V. I. Zannis, and D. Atkinson. Structural studies of the N- and C-terminal truncated human apolipoprotein A-I. (2000) 44-th Annual Biophys. Society Meeting, New Orleans, LA, Feb. 12-16. Abstract: Biophys. J. 2000, 78(1/2):163A, #960.

62. Gorshkova I.N., K. Liadaki, O. Gursky, V.I. Zannis, and D. Atkinson. Probing the solution structure of apolipoprotein A-I by mutations, circular dichroism, and fluorescence spectroscopy. (2000) 44-th Annual Biophys. Society Meeting, New Orleans, LA, Feb. 12-16. Abstract: Biophys. J. 78(1/2):421A, #2482.

63. Poulos G. W. and D. Atkinson. Three-dimensional structure of low-density lipoprotein via cryo-electron microscopy. (2000) 44-th Annual Biophys. Society Meeting, New Orleans, LA, Feb. 12-16. Abstract: Biophys. J. 2000, 78(1/2):485A, #2855.

64. Irina Gorshkova, Tong Liu, Vassilis I. Zannis, and David Atkinson . Small changes in the length of the N-terminal deletion of apolipoprotein A-I induce a significantly different protein folding. (2001) Abstracts of 45th Biophysical Society Meeting, Biophysical J., 80 (1): p. 557a. 2001.

65. Yang Chao, Olga Gursky and David Atkinson. Conformational Studies of a Consensus Sequence Peptide (CSP) of Apolipoproteins by CD and X-ray Crystallography. (2001) Abstracts of 45th Biophysical Society Meeting, Biophysical J., 80 (1): p. 59a. 2001.

66. Yiling Fang, Olga Gursky and David Atkinson. Structural Studies of Terminally Truncated apolipoprotein A-1. (2001) Abstracts of 45th Biophysical Society Meeting, Biophysical J., 80 (1): p. 61a. 2001.

67. Hassan Khachfe and David Atkinson . Structural Analysis and Characterization of the 17% N-terminal Domain of Apolipoprotein B-100 using CD Spectroscopy . (2001) Abstracts of 45th Biophysical Society Meeting, Biophysical J., 80 (1): p. 62a. 2001.

68. Gorshkova I. N., Horng Y. K., Zannis V. I., and Atkinson D. Effects of Mutations in Apolipoprotein A-I Suggest the Presence of Disordered Structure in the Region 121-142 of the Lipid-Free Protein. Seventeenth Symposium of the Protein Society, Boston, MA. 2003. Protein Science 12(suppl. 3) 157.

69. Wally J., Chao Y., and Atkinson D . Overlapping Apolipoprotein A-I Peptides Suggest a Variably Folded AB Repeat in Lipid-Free and Lipid Bound Forms. Seventeenth Symposium of the Protein Society, Boston, MA. 2003 Protein Science 12(suppl. 3) 112.

70. Luo D. and Atkinson D . Structure and stability of a consensus sequence (CSP-BABA) of apolipoproteins. Seventeenth Symposium of the Protein Society, Boston, MA. 2003. Protein Science 12(suppl. 3) 114.

71. Zhu H. and Atkinson D . Conformation and Lipid Binding of the N-Terminal (1-44) Domain of Human Apolipoprotein A-I (apoA-I). Seventeenth Symposium of the Protein Society, Boston, MA. 2003. Protein Science 12(suppl. 3) 113.

72. Lipid-Induced Secondary Structural Changes in an Apolipoprotein A-I Peptide. Wally J. and Atkinson D . 47th Annual Meeting, Biophysical Society, San Antonio TX. 2003. Biophysical J.84:2 1853-Pos 380a.

73. Structure, stability and lipid interactions of a peptide model for the N-terminal domain of human Apolipoprotein A-I (apoA-I). Hongli Zhu and David Atkinson. 48th Annual Meeting, Biophysical Society, Baltimore MD. 2004. Biophysical J.86:1 1954-pos 376a.

74. Differential lipid affinity of overlapping apolipoprotein A-I peptides. Jeremy Wally and David Atkinson. 48th Annual Meeting, Biophysical Society, Baltimore MD. 2004. Biophysical J.86:1 1955-pos 376a.

Lectures, Seminars and Presentations

Lectures and Seminars Given in Universities, National and International Scientific Meetings, Industry, etc

1. Small angle x-ray scattering. Annual meeting Nation Cement and Concrete Association, England (1973)

2. Small-angle x-ray scattering studies of porcine plasma lipoproteins.3rd International Conference on X-Ray and Neutron Small-Angle Scattering, Grenoble, France (1973).

3. Solution studies of the structure and aggregation of globular proteins. 12th Prague Microsymposium on Macromolecules – Organized Structures in Polymer Solutions and Gels, Prague, Czechoslovakia (1973).

4. Small angle x-ray scattering studies of native and reassembled lipoproteins - I and II. Biophysics Institute, Boston University School of Medicine (1975).

5. Interaction of apoprotein from porcine high-density lipoprotein with dimyristoyl lecithin: The structure of the complexes. 20th Annual Biophysical Society Meeting, Seattle, Washington (1976)

6. The structure of the complexes formed from dimyristoyl lecithin and the apoproteins of high density lipoproteins. Departments of Medicine and Biochemistry, University of Chicago. (1976)

7. The structure of plasma lipoproteins. Gordon Conference on Lipid Metabolism, (1976).

8. Small angle x-ray scattering studies of plasma lipoproteins. Gordon Conference on Diffraction Methods in Molecular Biology (1976)

9. Small-angle x-ray scattering studies of the cholesterol ester organization in plasma lipoproteins. 4th International Conference on Small Angle Scattering of X-rays and Neutrons. Gatlinburg, USA (1977).

10. The molecular organization of Plasma Lipoproteins; Symposium on The Genetics of Atherosclerosis. The Children's Hospital, Philadelphia (1977)

11. Structural studies on Low Density Lipoprotein, Department of Physiology and Biochemistry, Medical College of Philadelphia (1977)

12. Structural studies of recombinant lipoproteins. 8th Annual ICN-UCLA Symposia Molecular and Cellular Biology, Keystone, USA (1979).

13. Neutron small-angle scattering of reassembled plasma lipoproteins. Meeting of American Crystallographic Association, Boston, MA (1979)

14. Localization of the apoprotein at the periphery of HDL disks: A model for nascent HDL. 52nd Scientific Sessions, American Heart Association (1979).

15. X-ray and neutron scattering studies of plasma lipoproteins. Conference on Lipoprotein Structure, New York Academy of Sciences (1979).

16. The Structure of Plasma Lipoproteins. Gordon Conference on Micelles and Macromolecular Catalysis (1981).

17. Structural studies of plasma lipoproteins. Department of Chemistry, Massachusetts Institute of Technology (1981).

18. The molecular organization of plasma lipoproteins. D. Atkinson. Established Investigators Meeting, AHA Research Committee Meeting (1982).

19. The reassembly of plasma lipoproteins. Department of Comparative Medicine, Bowman Gray School of Medicine (1982).

20. The structure and reassembly of plasma lipoproteins. Gladstone Foundation Laboratories (1982).

21. Structural studies of plasma lipoproteins. 32nd Brookhaven Symposium in Biology; Neutrons in Biology (1982).

22. The molecular organization of plasma lipoproteins and lipoprotein models. Gordon Conference on Lipid Metabolism (1982).

23. Plasma lipoproteins and model systems, Department of Biophysical Chemistry, University of Cologne, Germany (1982).

24. The structure and reassembly of plasma lipoproteins. 5th Annual Meeting Of the European Lipoprotein Club, Tutzing, Germany (1982).

25. Neutron scattering studies of plasma lipoproteins. Neutron Scattering Symposium, Biophysical Society Meeting, San Diego (1983).

26. The molecular organization of plasma lipoproteins. Gastroenterology Department, Harvard University School of Medicine (1984)

27. Reassembly of low density lipoprotein. Gordon Conference on Lipid Metabolism (1984).

28. Structure of plasma lipoproteins and lipoprotein models. American Crystallographic Association Annual Meeting. McMaster University, Hamilton, Ontario, Canada, (1986).

29. The plasma lipoproteins, Structural Studies Colloquia, Medical Research Council Laboratory for Molecular Biology, Cambridge, England(1988).

30. Electron microscopy of unstained, frozen hydrated low density lipoprotein. D. Atkinson 61st Scientific Sessions, American Heart Association Meetings, Washington, DC, November 14-17, (1988).

31. The structure of low density lipoprotein from electron microscopy. Duel Conference on Lipids, Sonoma, California (1989).

32. Electron microscopy of unstained, frozen hydrated low density lipoprotein. 33rd Annual Biophysical Society Meeting, Cincinnati, Ohio(1989)

33. Electron microscopy of low density lipoprotein. Department of Physics, Boston University (1989).

34. Electron microscopy of LDL. Seminar, Beth Israel Hospital (1989).

35. Structure of plasma lipoproteins. Seminar, Human Nutrition Research Center, Tufts University (1989).

36. The molecular Organization of Plasma Lipoproteins. Department of Chemistry, University of Massachusetts, Boston (1990).

37. The molecular organization of the plasma lipoprotein. Department of Biochemistry, Simon Fraser University (1990).

38. The molecular organization of the plasma lipoprotein. Department of Biochemistry, University at U Mass. Boston (1990).

39. The molecular structure of the plasma lipoprotein. Department of Pharmacology, Boston University School of Medicine (1993).

40. The structure of LDL from cryoelectron microscopy. University of Alabama, Birmingham (1994).

41. The conformation and structure of plasma apolipoproteins. Gordon Conference on Lipid Metabolism, New Hampshire (1994)

42. Plasma Lipoprotein Structure and Function. Department of Biophysics, Boston University School of Medicine (1995).

43. Departmental Computer Resources. Department of Biophysics, Boston University School of Medicine (1996).

44. Plasma Lipoprotein Structure and Function. Department of Biophysics, Boston University School of Medicine (1996).

45. Plasma Lipoprotein Structure and Function. Department of Biophysics, Boston University School of Medicine (1997).

46. Apolipoprotein A-1: Conformation and Stability. HDL Workshop, Atlanta.(1998)

47. Departmental Computer Resources. Department of Biophysics, Boston University School of Medicine (1999).

48. Plasma Lipoprotein Structure and Function. Department of Medicinal Chemistry, University of Connecticut. (1999)

49. Apolipoprotein A-1: Conformation, Structure and Stability, University Of Alabama, Birmingham (1999)

50. Plasma Lipoprotein Structure and Function. Department of Physiology and Biophysics Retreat, Sargent Camp. (2000)

51. Fat(Triglycerides), Cholesterol and the Molecular Basis of Lipid Transport and Metabolism Newton North High School, Advanced Placement Biology Course (2000)

52. Plasma Lipoprotein Structure and Function. Department of Physiology and Biophysics Retreat, Sargent Camp. (2001)

53. Plasma Lipoprotein Structure and Function. Department of Physiology and Biophysics Retreat, Sargent Camp. (2002)

54. Plasma Lipoprotein Structure and Function. Department of Physiology and Biophysics Retreat, Sargent Camp. (2003)

55. Structure of Low Density Lipoprotein via Cryo-Electron Microscopy. University Of Alabama, Birmingham (2003)

56. Plasma Lipoprotein Structure and Function. Department of Physiology and Biophysics, Retreat. Woods Hole (2004)

57. The Conformation, Structure and Stability of Apolipoprotein A-I and Peptide Models. The 2004 HDL Workshop Crete, Greece, (2004)