crohn’s disease stjepan ĆuriĆ mentor: a. Žmegač horvat
TRANSCRIPT
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CROHN’S DISEASESTJEPAN ĆURIĆMentor: A. Žmegač Horvat
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Dr. Burrill Bernard Crohn
in 1932 he described a series of patients with inflammation of the terminal ileum, the area most commonly affected by the illness
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What is Crohn’s?
inflammatory disease of the intestines that may affect any part of the gastrointestinal tract from mouth to anus
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Symptoms
abdominal pain diarrhea (which may be bloody) vomiting weight loss skin rashes arthritis inflammation of the eye
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Causes
genetics (mutations in CARD15)
environmental factors
immune system
microbes (Mycobacterium avium subspecies paratuberculosis)
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endoscopy radiologic tests blood tests comparison with ulcerative colitis
Diagnosis
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Treatment
medication (corticosteroids, 5-aminosalicyilic acid, azathioprine, mercaptopurine, methotrexate, infliximab)
lifestyle changes (hydration)
surgery
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References:
Mayo Clinic: Crohn's Disease
National Digestive Diseases Information Clearinghouse
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THANK YOU FOR YOUR ATTENTION!