Cover Picture

Sridhar Narayan, John Muldoon, M. G. Finn, Valery V. Fokin,Hartmuth C. Kolb, and K. Barry Sharpless*

Reactions “on water” offer ease of product isolation and may be substantially fasterthan the same reactions performed in organic solvents. The cover picture shows thetime course of an ene reaction between (S)-b-pinene and diethyl azodicarboxylateperformed on water. The insoluble reactants float on water, whereas the productdescends under the water layer and is isolated as a colorless oil. For more details onthese reactions, see the Communication by K. B. Sharpless and co-workers onpage 3275 ff.

EpigeneticsA. Giannis and co-workers delve into the secrets of the histone code in their Reviewon page 3186. What influence do histones have on the activation and inactivation ofgene sequences?

Crystal GrowthTwo growth processes, habit formation and branching growth, determine the crystalshape of electrochemically generated Cu2O crystals. In their Communication onpage 3218 ff., K.-S. Choi and M. J. Siegfried explain how these processes can becontrolled.

Mesoporous MaterialsThe mesoporous silica superstructure SBA-1 was studied to obtain a formulation interms of curvature, which is important for surfactant structures and the mechanism offormation of inorganic replicas. The results are presented by M. W. Anderson and co-workers on page 3243 ff.