commissioning a varian -...

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Corey Bridger a , Alexandre Santos a,b , Paul Reich b a) School of Physical Science, University of Adelaide, South Australia b) Department of Medical Physics, Royal Adelaide Hospital, South Australia COMMISSIONING A VARIAN LEIPZIG-STYLE APPLICATOR FOR HDR BRACHYTHERAPY 1

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C o r e y B r i d g e r a , A l e x a n d r e S a n t o s a , b , P a u l R e i c h b

a ) S c h o o l o f P h y s i c a l S c i e n c e , U n i v e r s i t y o f A d e l a i d e , S o u t h A u s t r a l i ab ) D e p a r t m e n t o f M e d i c a l P h y s i c s , R o y a l A d e l a i d e H o s p i t a l , S o u t h A u s t r a l i a

COMMISSIONING A VARIAN LEIPZIG-STYLE

APPLICATOR FOR HDR BRACHYTHERAPY

1

Geometric integrity check Determination of optimal source position inside applicator Validation of the TPS dose engine (Acuros) Treatment planning procedure

OUTLINE

EQUIPMENT

Leipzig-style applicator

30 mm 35 mm 40 mm 45 mm

GammaMedplus iXBrachyVision V 13.7

LENGTH CHECK

Length gauge (1300 mm)Leipzig connected to source guide tube

Results: 1300 1 mm

Dimension check

Results: diameters within 0.5 mm of manufacturer

OPTIMAL SOURCE POSITION INSIDE APPLICATOR

Films (30 mm insert)

VALIDATING ACUROS

Water (blue)

Air (white)

MEASUREMENTS (FILM)

(a) Profiles (2, 3, 5 & 10 mm depths) (b) PDDs

GafchromicEBT3 film in Solid Water

PROFILE COMPARISONS (3 MM DEPTH)

40 mm insert

0

0.5

1

1.5

2

2.5

3

3.5

-45 -25 -5 15 35Distance (mm)

Dose

(Gy)

TPS (Acuros) Film MC

45 mm insert

00.5

11.5

22.5

33.5

-30 -20 -10 0 10 20 30Distance (mm)

Do

se (

Gy)

TPS (Acuros) Film MC data

35 mm insert

0

0.5

1

1.5

2

2.5

3

3.5

-40 -20 0 20 40Distance (mm)

Dose

(Gy)

TPS (Acuros) Film MC

30 mm insert

00.5

11.5

22.5

33.5

-20 -10 0 10 20

Distance (mm)

Dose

(Gy)

MC

TPS (Acuros)

Film

Chart2

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2.06679

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2.23354

2.31691

2.40028

2.48365

2.56702

2.6504

2.73377

2.81714

2.90051

2.98389

3.06726

3.15063

3.234

3.31737

3.40075

3.48412

3.56749

3.65086

3.73423

3.81761

3.90098

3.98435

4.06772

4.1511

4.23447

4.31784

4.40121

4.48458

4.56796

4.65133

4.7347

4.81807

4.90144

4.98482

5.06819

5.15156

5.23493

5.31831

5.40168

5.48505

5.56842

5.65179

5.73517

5.81854

5.90191

5.98528

6.06865

6.15203

6.2354

6.31877

6.40214

6.48552

6.56889

6.65226

6.73563

6.819

6.90238

6.98575

7.06912

7.15249

7.23586

7.31924

7.40261

7.48598

7.56935

7.65273

7.7361

7.81947

7.90284

7.98621

8.06959

8.15296

8.23633

8.3197

8.40307

8.48645

8.56982

8.65319

8.73656

8.81994

8.90331

8.98668

9.07005

9.15342

9.2368

9.32017

9.40354

9.48691

9.57028

9.65366

9.73703

9.8204

9.90377

9.98715

10.07052

10.15389

10.23726

10.32063

10.40401

10.48738

10.57075

10.65412

10.7375

10.82087

10.90424

10.98761

11.07098

11.15436

11.23773

11.3211

11.40447

11.48784

11.57122

11.65459

11.73796

11.82133

11.90471

11.98808

12.07145

12.15482

12.23819

12.32157

12.40494

12.48831

12.57168

12.65505

12.73843

12.8218

12.90517

12.98854

13.07192

13.15529

13.23866

13.32203

13.4054

13.48878

13.57215

13.65552

13.73889

13.82226

13.90564

13.98901

14.07238

14.15575

14.23913

14.3225

14.40587

14.48924

14.57261

14.65599

14.73936

14.82273

14.9061

14.98947

15.07285

15.15622

15.23959

15.32296

15.40634

15.48971

15.57308

15.65645

15.73982

15.8232

15.90657

15.98994

16.07331

16.15668

16.24006

16.32343

16.4068

16.49017

16.57355

16.65692

16.74029

16.82366

16.90703

16.99041

17.07378

17.15715

17.24052

17.32389

17.40727

17.49064

17.57401

17.65738

17.74076

17.82413

17.9075

17.99087

18.07424

18.15762

18.24099

18.32436

18.40773

18.4911

18.57448

18.65785

18.74122

18.82459

18.90797

18.99134

19.07471

19.15808

19.24145

19.32483

19.4082

19.49157

19.57494

19.65831

19.74169

19.82506

19.90843

19.9918

20.07518

20.15855

20.24192

20.32529

20.40866

20.49204

20.57541

20.65878

20.74215

20.82552

20.9089

20.99227

21.07564

21.15901

21.24239

21.32576

21.40913

21.4925

21.57587

21.65925

21.74262

21.82599

21.90936

21.99274

22.07611

22.15948

22.24285

22.32622

22.4096

22.49297

22.57634

22.65971

22.74308

22.82646

22.90983

22.9932

23.07657

23.15995

23.24332

23.32669

23.41006

23.49343

23.57681

23.66018

23.74355

23.82692

23.91029

23.99367

24.07704

24.16041

24.24378

24.32716

24.41053

24.4939

24.57727

24.66064

24.74402

24.82739

24.91076

24.99413

25.0775

25.16088

25.24425

25.32762

25.41099

25.49437

25.57774

25.66111

25.74448

25.82785

25.91123

25.9946

26.07797

26.16134

26.24471

26.32809

26.41146

26.49483

26.5782

26.66158

26.74495

26.82832

26.91169

26.99506

27.07844

27.16181

27.24518

27.32855

27.41192

27.4953

27.57867

27.66204

27.74541

27.82879

27.91216

27.99553

28.0789

28.16227

28.24565

28.32902

28.41239

28.49576

28.57913

28.66251

28.74588

28.82925

28.91262

28.996

29.07937

29.16274

29.24611

29.32948

29.41286

29.49623

29.5796

29.66297

29.74634

29.82972

29.91309

29.99646

30.07983

30.16321

30.24658

30.32995

30.41332

30.49669

30.58007

30.66344

30.74681

30.83018

30.91355

30.99693

31.0803

31.16367

31.24704

31.33042

31.41379

31.49716

31.58053

31.6639

31.74728

31.83065

31.91402

31.99739

32.08076

32.16414

32.24751

32.33088

32.41425

32.49763

32.581

32.66437

32.74774

32.83111

32.91449

32.99786

33.08123

33.1646

33.24798

33.33135

33.41472

33.49809

33.58146

33.66484

33.74821

33.83158

33.91495

33.99832

34.0817

34.16507

34.24844

34.33181

34.41519

34.49856

34.58193

34.6653

34.74867

34.83205

34.91542

34.99879

35.08216

35.16553

35.24891

35.33228

35.41565

35.49902

35.5824

35.66577

35.74914

35.83251

35.91588

35.99926

36.08263

36.166

36.24937

36.33274

36.41612

36.49949

36.58286

36.66623

36.74961

36.83298

36.91635

36.99972

37.08309

37.16647

37.24984

37.33321

37.41658

37.49995

37.58333

37.6667

37.75007

37.83344

37.91682

38.00019

38.08356

38.16693

38.2503

38.33368

38.41705

38.50042

38.58379

38.66716

38.75054

38.83391

38.91728

39.00065

39.08403

39.1674

39.25077

39.33414

39.41751

39.50089

39.58426

39.66763

39.751

39.83437

39.91775

40.00112

40.08449

40.16786

40.25124

40.33461

40.41798

40.50135

40.58472

40.6681

40.75147

40.83484

40.91821

41.00158

41.08496

41.16833

41.2517

41.33507

41.41845

41.50182

41.58519

41.66856

41.75193

41.83531

41.91868

42.00205

42.08542

42.16879

42.25217

42.33554

42.41891

42.50228

42.58566

42.66903

42.7524

42.83577

42.91914

43.00252

43.08589

43.16926

43.25263

43.336

43.41938

43.50275

43.58612

43.66949

43.75287

43.83624

43.91961

44.00298

44.08635

44.16973

44.2531

44.33647

44.41984

44.50321

44.58659

44.66996

44.75333

44.8367

44.92008

45.00345

45.08682

45.17019

45.25356

45.33694

45.42031

45.50368

45.58705

45.67043

45.7538

45.83717

45.92054

46.00391

46.08729

46.17066

46.25403

46.3374

46.42077

46.50415

46.58752

46.67089

46.75426

46.83764

46.92101

47.00438

47.08775

47.17112

47.2545

47.33787

47.42124

47.50461

47.58798

47.67136

47.75473

47.8381

47.92147

48.00485

48.08822

48.17159

48.25496

48.33833

48.42171

48.50508

48.58845

48.67182

48.75519

48.83857

48.92194

49.00531

49.08868

49.17206

49.25543

49.3388

49.42217

49.50554

49.58892

49.67229

49.75566

49.83903

49.9224

50.00578

50.08915

50.17252

50.25589

50.33927

50.42264

50.50601

50.58938

50.67275

50.75613

50.8395

50.92287

51.00624

51.08961

51.17299

51.25636

51.33973

51.4231

51.50648

51.58985

51.67322

51.75659

51.83996

51.92334

52.00671

52.09008

52.17345

52.25682

52.3402

52.42357

52.50694

52.59031

52.67369

52.75706

52.84043

52.9238

53.00717

53.09055

53.17392

53.25729

53.34066

53.42403

53.50741

53.59078

53.67415

53.75752

53.8409

53.92427

54.00764

54.09101

54.17438

54.25776

54.34113

54.4245

54.50787

54.59124

54.67462

54.75799

54.84136

54.92473

55.00811

55.09148

55.17485

55.25822

55.34159

55.42497

55.50834

55.59171

55.67508

55.75845

55.84183

55.9252

56.00857

56.09194

56.17532

56.25869

56.34206

56.42543

56.5088

56.59218

56.67555

56.75892

56.84229

56.92567

57.00904

57.09241

57.17578

57.25915

57.34253

57.4259

57.50927

57.59264

57.67601

57.75939

57.84276

57.92613

58.0095

58.09288

58.17625

58.25962

58.34299

58.42636

58.50974

58.59311

58.67648

58.75985

58.84322

58.9266

59.00997

59.09334

59.17671

59.26009

59.34346

59.42683

59.5102

59.59357

59.67695

59.76032

59.84369

59.92706

60.01043

60.09381

60.17718

60.26055

60.34392

60.4273

60.51067

60.59404

60.67741

60.76078

60.84416

60.92753

61.0109

61.09427

61.17764

61.26102

61.34439

61.42776

61.51113

61.59451

61.67788

61.76125

61.84462

61.92799

62.01137

62.09474

62.17811

62.26148

62.34485

62.42823

62.5116

62.59497

62.67834

62.76172

62.84509

62.92846

63.01183

63.0952

63.17858

63.26195

63.34532

63.42869

63.51206

63.59544

63.67881

63.76218

63.84555

63.92893

64.0123

64.09567

64.17904

64.26241

64.34579

64.42916

64.51253

64.5959

64.67927

64.76265

64.84602

64.92939

65.01276

65.09614

65.17951

65.26288

65.34625

65.42962

65.513

65.59637

65.67974

65.76311

65.84648

65.92986

66.01323

66.0966

66.17997

66.26335

66.34672

66.43009

66.51346

66.59683

66.68021

66.76358

66.84695

66.93032

67.01369

67.09707

67.18044

67.26381

67.34718

67.43056

67.51393

67.5973

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67.76404

67.84742

67.93079

68.01416

68.09753

68.18091

68.26428

68.34765

68.43102

68.51439

68.59777

68.68114

68.76451

68.84788

68.93125

69.01463

69.098

69.18137

69.26474

69.34812

69.43149

69.51486

69.59823

69.6816

69.76498

69.84835

69.93172

70.01509

70.09846

70.18184

70.26521

70.34858

70.43195

70.51533

70.5987

70.68207

70.76544

70.84881

70.93219

71.01556

71.09893

71.1823

71.26567

71.34905

71.43242

71.51579

71.59916

71.68254

71.76591

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71.93265

72.01602

72.0994

72.18277

72.26614

72.34951

72.43288

72.51626

72.59963

72.683

72.76637

72.84975

72.93312

73.01649

73.09986

73.18323

73.26661

73.34998

73.43335

73.51672

73.60009

73.68347

73.76684

73.85021

73.93358

74.01696

74.10033

74.1837

74.26707

74.35044

74.43382

74.51719

74.60056

74.68393

74.7673

74.85068

74.93405

75.01742

75.10079

75.18417

75.26754

75.35091

75.43428

75.51765

75.60103

75.6844

75.76777

75.85114

75.93451

76.01789

76.10126

76.18463

76.268

76.35138

76.43475

76.51812

76.60149

76.68486

76.76824

76.85161

76.93498

77.01835

77.10172

77.1851

77.26847

77.35184

77.43521

77.51859

77.60196

77.68533

77.7687

77.85207

77.93545

78.01882

78.10219

78.18556

78.26893

78.35231

78.43568

78.51905

78.60242

78.6858

78.76917

78.85254

78.93591

79.01928

79.10266

79.18603

79.2694

79.35277

79.43615

79.51952

79.60289

79.68626

79.76963

79.85301

79.93638

80.01975

80.10312

80.18649

80.26987

80.35324

80.43661

80.51998

80.60336

80.68673

80.7701

80.85347

80.93684

81.02022

81.10359

81.18696

81.27033

81.3537

81.43708

81.52045

81.60382

81.68719

81.77057

81.85394

81.93731

82.02068

82.10405

82.18743

82.2708

82.35417

82.43754

82.52091

82.60429

82.68766

82.77103

82.8544

82.93778

83.02115

83.10452

83.18789

83.27126

83.35464

83.43801

83.52138

83.60475

83.68812

83.7715

83.85487

83.93824

84.02161

84.10499

84.18836

84.27173

84.3551

84.43847

84.52185

84.60522

84.68859

84.77196

84.85533

84.93871

85.02208

85.10545

85.18882

85.2722

85.35557

85.43894

85.52231

85.60568

85.68906

85.77243

85.8558

85.93917

86.02254

86.10592

86.18929

86.27266

86.35603

86.43941

86.52278

86.60615

86.68952

86.77289

86.85627

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87.02301

87.10638

87.18975

87.27313

87.3565

87.43987

87.52324

87.60662

87.68999

87.77336

87.85673

87.9401

88.02348

88.10685

88.19022

88.27359

88.35696

88.44034

88.52371

88.60708

88.69045

TPS (Acuros)

Film

MC

Distance (mm)

Dose (Gy)

40 mm insert

0

0.3657372431

1.2867032012

0

0.4494567497

1.3703677591

0

0.5366348621

1.4655722561

0

0.6119442622

1.5521217988

0

0.6848323878

1.65598125

0

0.7734247387

1.762725686

0

0.8192799248

1.881010061

0

0.8443603351

1.9935244665

0

0.8688728241

2.1146938262

0

0.885726058

2.2445181402

0

0.912708628

2.3714574695

0

0.9174030129

2.5157067073

0

0.9409487717

2.6426460366

0

0.9542498317

2.7493904726

0

0.9845418362

2.8705598323

0

1.0201119238

2.9657643293

0

1.0264516431

3.0465439024

0

1.0405739965

3.1157835366

0

1.0670396709

3.1446333841

0

1.0868187375

3.1619432927

0

1.0900067563

3.1475183689

0

1.1274868634

3.1100135671

0

1.1564936654

3.0494288872

0

1.1843324247

2.957109375

0

1.2114151061

2.8705598323

0

1.2137000682

2.7609304116

0

1.2274997925

2.6311060976

0

1.250378377

2.507051753

0

1.2846805592

2.3656875

0

1.3298725048

2.258943064

0

1.3485839256

2.117578811

0

1.3850400789

1.999294436

0

1.4040748868

1.8752400915

0

1.4527021258

1.7656106707

0

1.4778025391

1.667521189

0

1.536137574

1.5578917683

0

1.5584049177

1.4569173018

0

1.5939324743

1.3732527439

0

1.6414483038

1.2867032012

0

1.6761785098

0

1.7228708627

0

1.7516190762

0

1.8019229908

0

1.8286144949

0

1.8785422721

0

1.9403328213

0

1.9863751572

0

2.0244456756

0

2.0851867415

0

2.1192525332

0

2.151795814

0

2.2281581001

0

2.2583386087

0

2.2978426351

0

2.346074891

0

2.365792049

0

2.4232826312

0

2.460279508

0

2.5274107698

0

2.5842938431

0

2.6316029282

0

2.6615443997

0

2.7112610632

0

2.7500880021

0

2.8261884549

0

2.8790494749

0

2.911860755

0

2.9292770117

0

2.9659962531

0

3.0048033605

0

3.0023693541

0

3.0452030644

0

3.0825714094

0

3.0904771615

0

3.12862292

0

3.1485703793

0

3.1610595643

0

3.1598532267

0

3.2174187198

0

3.1987110601

0

3.2120735901

0

3.2183854972

0

3.1689419387

0

3.1429415664

0

3.1621392445

0

3.1698965618

0

3.1885277018

0

3.1475578385

0

3.1206358126

0

3.1095325548

0

3.0687924482

0

3.0637778087

0

3.0062036604

0

2.9717814271

0

2.9161918392

0

2.9112085924

0

2.8958883828

0

2.7975114359

0

2.7734587238

0

2.7237408499

0

2.6795793821

0

2.5866019976

0

2.567010876

0

2.5408710129

0

2.5087190065

0

2.452103049

0

2.3763776073

0

2.3523178242

0

2.2971130908

0

2.264338432

0

2.1858715758

0

2.1313796329

0

2.1132557899

0

2.0563166717

0

2.0381489068

0

1.9864182794

0

1.925614977

0

1.8642479088

0

1.8212488329

0

1.7999716498

0

1.7353218915

0

1.7142395549

0

1.6610374929

0

1.625599004

0

1.5924864765

0

1.5818175841

0

1.5372275468

0

1.4924330414

0

1.4644322349

0

1.4495029357

0

1.4099673644

0

1.3800024149

0

1.3359516151

0

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Calibration data

Red filterEquationy = -0.000000000000479394717051473000x3 + 0.000000050699425879280600000000x2 - 0.001913429797833270000000000000x + 25.799985559117700000000000000000

TestDoseAreaminmaxGrey valuestd devk=2 std devRel. % errlinac 1% errCurve valueRel. % errsum of % errave % err

101820372693856738080.804114.99229.980.60392632471-0.01681982151.16821530792.5837467664

20.251820349503630135940.261103.025206.050.57331247540.26390945475.27054049115.3951167052

30.51820318943423033871.626138.073276.1460.81527234620.52629395644.99605896915.1599684322

411820293533093030627.715105.397210.7940.68824592370.98168145131.86603797652.2261581662

521820253232606425712.50699.939199.8780.77735713511.97055662941.49416515791.9587786078

631820193022260822343.929127.816255.6321.14407810733.0104338030.34658802291.558537126

741820194672013719848.99184.263168.5260.84904063894.04607792151.13882931571.7371822635

851820173191835118038.25777.103154.2060.85488304114.96786660520.64682483141.4660175226

Green filterEquationy = -0.000000000000440313875676681000x3 + 0.000000049087241938156500000000x2 - 0.002030235371619460000000000000x + 30.140219677544900000000000000000

101820355493718236621.12142.433284.8660.7778735331-0.00311360081.26692037381.9996414366

20.251820340343592935437.834133.227266.4540.75189132610.24296158532.89692491123.1555529638

30.51820315553483334146.054177.291354.5821.03842745640.51902853343.6661825233.9394448688

411820303843252132062.557134.123268.2460.83663321050.99475026140.52774438251.4065806988

521820277242900728379.038156.048312.0961.0997412951.99382836650.3095368481.5183029922

631820208332590425489.177176.813353.6261.38735746552.99136382380.28870363991.7343905352

741820226402346423071.079113.242226.4840.98167927044.02127430210.52904379311.4978589803

851820206272158921155.343113.127226.2541.06948868664.98990672830.20227375441.4780800799

Blue filterEquationy = -0.000000000009979328105292880000x3 + 0.000000617836705353640000000000x2 - 0.013572726705270300000000000000x + 104.408701667079000000000000000000

101820197442062020291.38194.53189.060.93172564250.01245415371.36678918384.9207520516

20.251820192382037520054.16888.858177.7160.88617987040.209078642219.572232405419.6177877472

30.51820183301994919648.722105.36210.721.07243616150.55013616699.11341044519.2306212825

411820181811943119157.69787.067174.1340.90895059050.97658469282.39767296912.7522766653

521820177341831118068.32684.202168.4040.9320398582.00922662230.45921262611.4420729985

631820135101746417185.189132.306264.6121.53976776162.97676141170.78066680651.9950752925

741820160251666216360.35882.079164.1581.00338880114.02519182510.62585402671.5487034413

851820152561597515698.68876.906153.8120.97977614444.99056648510.1890269351.4126898015

Calibration data

Blue channel

DP centering

2 mm depthdistdose3 mm depthdistdose5 mmdistdose10 mmdistdose

max dose3.7525825849Left 50%13.75833333331.8884921177max dose3.2183854972Left 50%13.05277777781.5939324743max dose2.4942552316Left 50%11.28888888891.2207211001max dose1.5019475742Left 50%12.70.7595252213

50% dose1.876291292550% dose1.609192748613.40555555561.641448303850% dose1.247127615811.64166666671.254229329850% dose0.7509737871

Right 50%42.68611111111.8625766605ave dose13.7583333333Right 50%43.39166666671.625599004ave dose13.2291666667Right 50%47.27222222221.2617115481ave dist11.46527777781.237475215Right 50%58.56111111110.7553702747ave dist12.70.7595252213

43.74444444441.592486476547.6251.2364668471

Distance (mm)Ave. Dose (Gy)50% doseLeft 50%Right 50%CentreFWHMDist (mm)Ave. Dose (Gy)50% doseLeft 50%Right 50%CentreFWHMDistance (mm)Ave. Dose (Gy)50% doseLeft 50%Right 50%CentreFWHMDistance (pixels)Ave. Dose (Gy)50% doseLeft 50%Right 50%CentreFWHM

00.27499814821.876291292513.658333333342.586111111128.122222222228.927777777800.36573724311.609192748613.102777777843.694444444428.398611111130.591666666701.247127615811.541666666747.52529.533333333335.983333333300.750973787112.558.521111111135.510555555646.0211111111

0.35277777780.29822223121.876291292513.658333333342.586111111128.12222222220.35277777780.44945674971.609192748613.102777777843.694444444428.39861111110.35277777781.247127615811.541666666747.52529.53333333330.35277777780.750973787112.558.521111111135.5105555556

0.70555555560.32633939241.876291292513.658333333342.586111111128.12222222220.70555555560.53663486211.609192748613.102777777843.694444444428.39861111110.70555555561.247127615811.541666666747.52529.53333333330.70555555560.750973787112.558.521111111135.5105555556

1.05833333330.38592381781.876291292513.658333333342.586111111128.12222222221.05833333330.61194426221.609192748613.102777777843.694444444428.39861111111.05833333331.247127615811.541666666747.52529.53333333331.05833333330.47714348420.750973787112.558.521111111135.5105555556

1.41111111110.46464969491.876291292513.658333333342.586111111128.12222222221.41111111110.68483238781.609192748613.102777777843.694444444428.39861111111.41111111111.247127615811.541666666747.52529.53333333331.41111111110.48084465680.750973787112.558.521111111135.5105555556

1.76388888890.5644915961.876291292513.658333333342.586111111128.12222222221.76388888890.77342473871.609192748613.102777777843.694444444428.39861111111.76388888891.247127615811.541666666747.52529.53333333331.76388888890.49810806020.750973787112.558.521111111135.5105555556

2.11666666670.671033931.876291292513.658333333342.586111111128.12222222222.11666666670.81927992481.609192748613.102777777843.694444444428.39861111112.11666666671.247127615811.541666666747.52529.53333333332.11666666670.48655019530.750973787112.558.521111111135.5105555556

2.46944444440.76785079791.876291292513.658333333342.586111111128.12222222222.46944444440.84436033511.609192748613.102777777843.694444444428.39861111112.46944444441.247127615811.541666666747.52529.53333333332.46944444440.50105510740.750973787112.558.521111111135.5105555556

2.82222222220.86366117441.876291292513.658333333342.586111111128.12222222222.82222222220.86887282411.609192748613.102777777843.694444444428.39861111112.82222222220.77137991681.247127615811.541666666747.52529.53333333332.82222222220.50947917740.750973787112.558.521111111135.5105555556

3.1750.92728719371.876291292513.658333333342.586111111128.12222222223.1750.8857260581.609192748613.102777777843.694444444428.39861111113.1750.77919364531.247127615811.541666666747.52529.53333333333.1750.51809028030.750973787112.558.521111111135.5105555556

3.52777777780.9657991791.876291292513.658333333342.586111111128.12222222223.52777777780.9127086281.609192748613.102777777843.694444444428.39861111113.52777777780.79148995971.247127615811.541666666747.52529.53333333333.52777777780.52762084950.750973787112.558.521111111135.5105555556

3.88055555560.99573928141.876291292513.658333333342.586111111128.12222222223.88055555560.91740301291.609192748613.102777777843.694444444428.39861111113.88055555560.81692572151.247127615811.541666666747.52529.53333333333.88055555560.53605339960.750973787112.558.521111111135.5105555556

4.23333333331.01880892761.876291292513.658333333342.586111111128.12222222224.23333333330.94094877171.609192748613.102777777843.694444444428.39861111114.23333333330.83331746781.247127615811.541666666747.52529.53333333334.23333333330.54687844760.750973787112.558.521111111135.5105555556

4.58611111111.04101550881.876291292513.658333333342.586111111128.12222222224.58611111110.95424983171.609192748613.102777777843.694444444428.39861111114.58611111110.85316549841.247127615811.541666666747.52529.53333333334.58611111110.55288642850.750973787112.558.521111111135.5105555556

4.93888888891.06452995281.876291292513.658333333342.586111111128.12222222224.93888888890.98454183621.609192748613.102777777843.694444444428.39861111114.93888888890.85404572191.247127615811.541666666747.52529.53333333334.93888888890.55461714630.750973787112.558.521111111135.5105555556

5.29166666671.07755351411.876291292513.658333333342.586111111128.12222222225.29166666671.02011192381.609192748613.102777777843.694444444428.39861111115.29166666670.88515446611.247127615811.541666666747.52529.53333333335.29166666670.57218790390.750973787112.558.521111111135.5105555556

5.64444444441.10450968751.876291292513.658333333342.586111111128.12222222225.64444444441.02645164311.609192748613.102777777843.694444444428.39861111115.64444444440.88386279341.247127615811.541666666747.52529.53333333335.64444444440.5802438830.750973787112.558.521111111135.5105555556

5.99722222221.13443677311.876291292513.658333333342.586111111128.12222222225.99722222221.04057399651.609192748613.102777777843.694444444428.39861111115.99722222220.89486964111.247127615811.541666666747.52529.53333333335.99722222220.59177417610.750973787112.558.521111111135.5105555556

6.351.16842616871.876291292513.658333333342.586111111128.12222222226.351.06703967091.609192748613.102777777843.694444444428.39861111116.350.96886655311.247127615811.541666666747.52529.53333333336.350.58923747620.750973787112.558.521111111135.5105555556

6.70277777781.20042118731.876291292513.658333333342.586111111128.12222222226.70277777781.08681873751.609192748613.102777777843.694444444428.39861111116.70277777780.94245900321.247127615811.541666666747.52529.53333333336.70277777780.5981248350.750973787112.558.521111111135.5105555556

7.05555555561.22820286141.876291292513.658333333342.586111111128.12222222227.05555555561.09000675631.609192748613.102777777843.694444444428.39861111117.05555555560.96305787671.247127615811.541666666747.52529.53333333337.05555555560.60360995250.750973787112.558.521111111135.5105555556

7.40833333331.26147749871.876291292513.658333333342.586111111128.12222222227.40833333331.12748686341.609192748613.102777777843.694444444428.39861111117.40833333330.99760568341.247127615811.541666666747.52529.53333333337.40833333330.6155358240.750973787112.558.521111111135.5105555556

7.76111111111.2791722391.876291292513.658333333342.586111111128.12222222227.76111111111.15649366541.609192748613.102777777843.694444444428.39861111117.76111111111.01249052811.247127615811.541666666747.52529.53333333337.76111111110.61774140180.750973787112.558.521111111135.5105555556

8.11388888891.30044139331.876291292513.658333333342.586111111128.12222222228.11388888891.18433242471.609192748613.102777777843.694444444428.39861111118.11388888891.00675540251.247127615811.541666666747.52529.53333333338.11388888890.62034612360.750973787112.558.521111111135.5105555556

8.46666666671.33810337591.876291292513.658333333342.586111111128.12222222228.46666666671.21141510611.609192748613.102777777843.694444444428.39861111118.46666666671.02824786921.247127615811.541666666747.52529.53333333338.46666666670.64764029930.750973787112.558.521111111135.5105555556

8.81944444441.37356901411.876291292513.658333333342.586111111128.12222222228.81944444441.21370006821.609192748613.102777777843.694444444428.39861111118.81944444441.05195097231.247127615811.541666666747.52529.53333333338.81944444440.64429731310.750973787112.558.521111111135.5105555556

9.17222222221.39653505911.876291292513.658333333342.586111111128.12222222229.17222222221.22749979251.609192748613.102777777843.694444444428.39861111119.17222222221.06937002471.247127615811.541666666747.52529.53333333339.17222222220.65205939630.750973787112.558.521111111135.5105555556

9.5251.4238342841.876291292513.658333333342.586111111128.12222222229.5251.2503783771.609192748613.102777777843.694444444428.39861111119.5251.10315032261.247127615811.541666666747.52529.53333333339.5250.6729154920.750973787112.558.521111111135.5105555556

9.87777777781.44990392791.876291292513.658333333342.586111111128.12222222229.87777777781.28468055921.609192748613.102777777843.694444444428.39861111119.87777777781.13876627261.247127615811.541666666747.52529.53333333339.87777777780.67688152110.750973787112.558.521111111135.5105555556

10.23055555561.48618919651.876291292513.658333333342.586111111128.122222222210.23055555561.32987250481.609192748613.102777777843.694444444428.398611111110.23055555561.1416184881.247127615811.541666666747.52529.533333333310.23055555560.68071827340.750973787112.558.521111111135.5105555556

10.58333333331.52951235041.876291292513.658333333342.586111111128.122222222210.58333333331.34858392561.609192748613.102777777843.694444444428.398611111110.58333333331.17404645291.247127615811.541666666747.52529.533333333310.58333333330.70737879650.750973787112.558.521111111135.5105555556

10.93611111111.56928423381.876291292513.658333333342.586111111128.122222222210.93611111111.38504007891.609192748613.102777777843.694444444428.398611111110.93611111111.1996791741.247127615811.541666666747.52529.533333333310.93611111110.71781455720.750973787112.558.521111111135.5105555556

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