clinical samples & disease state plasma newsflash october 2016 final

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Clinical Samples & Disease State Plasma Current Biobank Inventory & Capabilities

* Although inventory information is correct on date of publishing, many of

the materials are in high demand and stocks are limited. Custom sample

collections are possible where published inventory items are already sold.

NEWS FLASH: October 2016


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Contents

BBI Biobank – What makes our products stand out for the crowd? 3

New Products 4

Disease State Plasma Availability 5-8

Clinical Sample Availability 9-11

Depleted Serum 12-14


the materials are in high demand and stocks are limited. Custom sample collections are possible where published inventory items are already sold.


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USA: 1-800-423-8199

China: +852 2159 9666

3

BBI BIOBANK

What makes our products stand out from the

crowd?

Able to collect directly from Blood Banks and Hospitals

Comprehensive characterisation

Variety of materials available:

Early disease phase

Low, medium & high titres

Rare antibodies

Clinical data / donor demographics held for many units

IRB / Ethical approval status for most materials

Comprehensive and detailed CofA’s

Operate under ISO 13485 and ISO 9001

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NEW PRODUCTS

NEW UNITS AVAILABLE NOW

HCV Plasma New Units

HBV/HCV Co-infected Units

C Reactive Protein Positive Plasma

Anti-Mitochondrial Antibodies Positive Plasma

Serum Amyloid A Positive Plasma

Glomerular Basement Membrane Antibodies Plasma

Bilirubin Positive Plasma

Lactate Dehydrogenase Positive Plasma

Acetylcholine Receptor Antibodies Positive Plasma

p-ANCA (MPO) Ab Positive Plasma

SITE UPDATES

Heat treatment now available for

Infectious Disease

Defibrination service available

HIV, HBV, HCV and Syphilis SCIPAC

mixed viral load and genotype sample

panels now available

COMING SOON

HIV-2 Serum Clinical Specimens

NMDA Receptor Ab Positive Plasma

Place your reservation now!


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Disease State Plasma Availability

Infectious Diseases

Autoimmune/Non-Infectious Diseases

Our Capabilities


the materials are in high demand and stocks are limited. Custom sample collections are possible where published inventory items are already sold.


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INFECTIOUS DISEASES High Demand selection from current inventory:

Disease Type Product

Code

Quantitative results & other

markers tested Volume available in stock

HCV Plasma Units SH259-4 Viral load and antibodies 1.7L

HBV/HCV Co-infected Units SH332-4 Positive for HBV and HCV Ab >1.5L

HAV SH265 HAV IgM 3.4L

HBsAg SH256 Hep B Core Total Ab HBsAb

Viral Load, Genotype, AD/AY 11.5L

Hep B Core IgM SH258 Hep B Core IgM 4.5L

Toxoplasma IgM SH275 Toxo IgM 2.8L

CMV IgM SH272 CMV IgM 2L

Parvovirus B19 SH331 Parvovirus B19 1.5L

ToRCH Negative Please

Enquire

Single, multiple or full ToRCH

IgG/IgM Negative >120L

Order your evaluation sample today Minimum order 1 unit 100ml+


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AUTOIMMUNE / NON-INFECTIOUS DISEASES Selection from current inventory:

Disease Type Product Code Quantitative results &

other Markers tested

Volume available in

stock (ml)

Anti-GBM SH336 Range of titres >10L

Bilirubin Positive Plasma SH294-3 Yes 2L

p-ANCA (MPO) SH152 Range of titres >20L

SAA SH127 Range of titres 20L

Thyroid Disease SH245 / SH244 Anti-Tg and Anti-TPO Individual units or custom

pools >10L

Raised IgE High Titre SH234 Yes >10L

Lactate Dehydrogenase

Positive Plasma SH102 Range of titres

>4L

Acetylcholine Receptor

Antibodies Pos Plasma SH103 Yes 3L

Anti-Mitochondrial Ab SH431 Positive for M2 Ab >10L

CRP Elevated SH100 Range of titres >8L

Order you evaluation sample today Minimum order size 100ml


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Infectious Disease Autoimmune Inflammation / Allergy

CMV IgG / IgM / Negative Anti-GBM CRP

EBV IgG / Negative Anti-RNP / Anti-SSA SAA

H. Pylori ANCA (Anti-MPO / Anti-PR3) IgE Raised Plasma

HAV Intrinsic Factor

HCV dsDNA Biochemistry

HBsAg HAMA Vitamin D

HBc IgM / Total Ab

Anti-HBs Rheumatoid Factor

HIV-1 Anti-Tg Organ Failure / Impairment

Lyme IgG / IgM Anti-TPO Renal Failure

Malaria TRAb

HSV IgG / Negative ANA Negative Pregnancy

Rubella IgG / Negative Anti-CCP Negative Pregnancy Serum / Plasma

Synthetic Rubella IgM Anti-Voltage Gated K Channel

Syphilis Anti-Mitochondrial Ab

Toxoplasma IgG / IgM / Negative

Parvovirus

HTLV-1

ToRCH IgG / IgM Negative

Conifection HIV / HBV / HCV / Syphilis

OUR CAPABILITIES Bulk Disease State Plasma


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Clinical Sample Availability

Infectious Disease SCIPAC Panels

Our Capabilities





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INFECTIOUS DISEASE SCIPAC PANELS Panel specifications

Citrated plasma

Extensive donor demographics

Tested for HIV1 & 2 Abs, HBsAg, HCV Ab, HIV-1 / HBV / HCV PCR and Syphilis

Individual donors (no duplicates)

Donor consent

Code no. Description Type Characteristics

SHK315-4V HIV-1 Plasma

Panel Mixed Viral Load

102->600,000 Copies/ml

9 Positive members 1 negative 2x1ml per panel

SHK256-4V HBsAg Plasma


149->600000000 IU/ml


SHK256-4G HBsAg Plasma

Panel Genotype Panel

Genotypes A-F


SHK259-4V HCV Plasma


70->10000000 IU/ml


SHK259-4G HCV Plasma

Panel Genotype Panel

Genotypes 1-6


SHK266-4M Syphilis Plasma

Panel Mixed Titre

1:4 to 1:256 RPR



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Infectious Disease Autoimmune Inflammation / Allergy

CMV IgG / IgM HAMA PCT

H. Pylori Rheumatoid Factor IgE

HAV Anti-Tg CRP

HCV Anti-TPO

HBsAg Centromere Ab Biochemistry

HIV-1 Type 1 Diabetes Vitamin D

Lyme IgG Diagnosis D-Dimer

Malaria

HSV IgG / IgM Cardiac / Cardiovascular Endocrine

Malaria Troponin I/T Free T3 / T4

Rubella IgG Myoglobin PTH

Syphilis CK-MB TSH

Toxoplasma IgG / IgM NT-Pro BNP Testosterone

Parvovirus Triglycerides Progesterone

Chagas Cholesterol LH

Bilirubin Oestrogen

Organ Failure / Impairment

Cancer Renal Failure

CA125 Type 2 Diabetes

CA19-9 C-Peptide

CA15-3

AFP Pregnancy

CEA Pregnancy Serum / Plasma

Subject to Availability.

Please enquire to set up a prospective

collection.

Check out our product brochure for our

collection capabilities.

Not on this list? BBI Biobank can look to collect any

other marker of interest, just ask. OUR CAPABILITIES Clinical Specimens


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Depleted Serum

An introduction to our standard products and custom services





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WHY USE OUR DEPLETED SERUMS?

“BBI have been manufacturing depleted serum for over 10 years. Our experience in this field has produced

a core range of high quality depleted serum products manufactured to ISO 9001 and ISO 13485 standards.”

Subject to lead time, volume requirement and specifications

Product Description Product Code Analyte Typical Batch

Volume

Vitamin D SF504 Vitamin D, Vitamin D3+D2 3-60L

Immunoglobulins SF505 IgG, IgA, IgM, IgE IgD 3-15L

IgG SF142 IgG, IgA, IgM 12-25L

Steroid SF236 Progesterone, Testosterone, Cortisol,

Estradiol 12-25L

Hormones SF512 Progesterone, Testosterone, Cortisol,

Estradiol, FSH, LH, Prolactin 6L

TSH SF219 TSH (Optional Triglycerides and

Cholesterol) 6-9L

TBG SF125 TBG 12-30L

T3 / T4 SF231 T3, T4, Free T3, Free T4 3L

CRP SF100 CRP 3L

Testosterone SF518 Testosterone 3-60L

Not on this list? Check out our next slide for more

information on our custom depletion service.


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CUSTOM DEPLETION SERVICE

“BBI offers a custom depletion service to our customers

when our standard product range does not meet their

requirements. Using our many years of experience,

working with our customers on custom depletion

products, BBI will work with you to scope, source and

manufacture the product(s) you need.”

Benefits:

Quick response time on project feasibility

Full and comprehensive scoping process

Raw materials required, sourced by BBI

Can be converted into a standard product and

potentially up-scaled* with long term commitment

Matrixes Considered for Custom Depletion

OTC Serum

Delipidated Defibrinated Plasma

*Subject to process used and specifications.

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clinical samples & disease state plasma newsflash october 2016 final

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